Details for: HLA DQB2

Gene ID: 3120

Symbol: HLA DQB2

Ensembl ID: ENSG00000232629

Description: major histocompatibility complex, class II, DQ beta 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 29.4448
    Cell Significance Index: -4.5800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 17.1501
    Cell Significance Index: -4.3500
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 4.5896
    Cell Significance Index: 66.6400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 3.7147
    Cell Significance Index: -4.5800
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 1.5757
    Cell Significance Index: 27.0700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.3428
    Cell Significance Index: 9.1700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0837
    Cell Significance Index: 9.8700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0181
    Cell Significance Index: 0.2800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.0163
    Cell Significance Index: 0.4800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0035
    Cell Significance Index: 1.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0001
    Cell Significance Index: -0.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0013
    Cell Significance Index: -0.9400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0018
    Cell Significance Index: -1.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0023
    Cell Significance Index: -4.3100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0027
    Cell Significance Index: -2.0400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0033
    Cell Significance Index: -0.1300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0054
    Cell Significance Index: -0.5500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0068
    Cell Significance Index: -4.2900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0075
    Cell Significance Index: -4.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0104
    Cell Significance Index: -4.7100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0106
    Cell Significance Index: -1.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0107
    Cell Significance Index: -1.9200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0114
    Cell Significance Index: -4.1000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0137
    Cell Significance Index: -2.7500
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.0140
    Cell Significance Index: -0.1500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0157
    Cell Significance Index: -1.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0213
    Cell Significance Index: -4.2200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0228
    Cell Significance Index: -3.8900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0285
    Cell Significance Index: -4.1500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0304
    Cell Significance Index: -4.1700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0368
    Cell Significance Index: -4.7500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0382
    Cell Significance Index: -1.7800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0436
    Cell Significance Index: -4.9900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0445
    Cell Significance Index: -2.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0460
    Cell Significance Index: -1.2900
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0557
    Cell Significance Index: -1.1100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0572
    Cell Significance Index: -3.6900
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.0605
    Cell Significance Index: -0.5000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0613
    Cell Significance Index: -1.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0624
    Cell Significance Index: -4.6500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0687
    Cell Significance Index: -0.7800
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0706
    Cell Significance Index: -3.0700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0720
    Cell Significance Index: -5.5300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0726
    Cell Significance Index: -2.5500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0747
    Cell Significance Index: -1.5200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0822
    Cell Significance Index: -5.0400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0832
    Cell Significance Index: -4.3200
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.0832
    Cell Significance Index: -0.8700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0880
    Cell Significance Index: -4.9400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0912
    Cell Significance Index: -1.9100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0963
    Cell Significance Index: -1.7800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0970
    Cell Significance Index: -3.1800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1080
    Cell Significance Index: -3.4400
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: -0.1099
    Cell Significance Index: -1.4400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1117
    Cell Significance Index: -2.7900
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.1168
    Cell Significance Index: -1.2800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1171
    Cell Significance Index: -4.0700
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1215
    Cell Significance Index: -3.5800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1245
    Cell Significance Index: -4.5700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1281
    Cell Significance Index: -4.8500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1312
    Cell Significance Index: -4.6100
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.1339
    Cell Significance Index: -1.1800
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.1344
    Cell Significance Index: -2.0100
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: -0.1344
    Cell Significance Index: -1.3300
  • Cell Name: medullary thymic epithelial cell (CL0002365)
    Fold Change: -0.1403
    Cell Significance Index: -1.5400
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: -0.1466
    Cell Significance Index: -0.6100
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.1488
    Cell Significance Index: -1.8400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1555
    Cell Significance Index: -4.4800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1559
    Cell Significance Index: -3.8900
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1565
    Cell Significance Index: -2.0800
  • Cell Name: myoepithelial cell (CL0000185)
    Fold Change: -0.1569
    Cell Significance Index: -1.7800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1667
    Cell Significance Index: -4.4500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.1668
    Cell Significance Index: -4.1600
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1685
    Cell Significance Index: -3.3000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1685
    Cell Significance Index: -4.8300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1719
    Cell Significance Index: -4.5200
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.1719
    Cell Significance Index: -0.9000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1723
    Cell Significance Index: -3.4600
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.1727
    Cell Significance Index: -1.6900
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1731
    Cell Significance Index: -2.9400
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1763
    Cell Significance Index: -3.6800
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.1764
    Cell Significance Index: -2.5800
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1773
    Cell Significance Index: -4.5300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1805
    Cell Significance Index: -4.6000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1827
    Cell Significance Index: -4.4300
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1856
    Cell Significance Index: -3.9400
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.1858
    Cell Significance Index: -1.5700
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.1859
    Cell Significance Index: -1.7800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.1865
    Cell Significance Index: -3.6700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1866
    Cell Significance Index: -3.6900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1880
    Cell Significance Index: -4.0600
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.1914
    Cell Significance Index: -1.5500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1924
    Cell Significance Index: -4.8100
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1994
    Cell Significance Index: -3.2300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2058
    Cell Significance Index: -4.2700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2112
    Cell Significance Index: -3.5400
  • Cell Name: myeloid dendritic cell, human (CL0001057)
    Fold Change: -0.2148
    Cell Significance Index: -1.1800
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.2180
    Cell Significance Index: -1.6800
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.2212
    Cell Significance Index: -2.6700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2227
    Cell Significance Index: -3.8500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The HLA DQB2 gene is a member of the MHC class II gene family, which is located on chromosome 6 in humans. It is one of the 15 MHC class II genes that encode proteins responsible for presenting peptide antigens to CD4+ T cells. The HLA DQB2 protein is a heterodimeric molecule, consisting of two polypeptide chains: the alpha chain (HLA-DQB1) and the beta chain (HLA-DQB2). The beta chain is encoded by the HLA DQB2 gene and is responsible for binding peptide antigens. **Pathways and Functions** The HLA DQB2 protein plays a critical role in the adaptive immune response by presenting peptide antigens to CD4+ T cells, which are a type of T-helper cell. This process involves the following steps: 1. **Peptide antigen processing**: Peptide antigens are generated from proteins that have been degraded by proteasomes. 2. **Antigen loading**: The peptide antigens are loaded onto the HLA DQB2 protein through a process involving the endoplasmic reticulum and the Golgi apparatus. 3. **MHC class II presentation**: The loaded HLA DQB2 protein is presented on the surface of antigen-presenting cells (APCs), such as dendritic cells and macrophages. 4. **T-cell activation**: CD4+ T cells recognize the HLA DQB2 protein and become activated, leading to the production of cytokines and the initiation of an immune response. **Clinical Significance** Dysfunction of the HLA DQB2 gene has been linked to several autoimmune and inflammatory diseases, including: 1. **Type 1 diabetes**: A autoimmune disease characterized by the destruction of pancreatic beta cells. 2. **Rheumatoid arthritis**: An autoimmune disease characterized by inflammation and joint damage. 3. **Multiple sclerosis**: An autoimmune disease characterized by demyelination and axonal damage in the central nervous system. 4. **Inflammatory bowel disease**: A chronic inflammatory disease characterized by inflammation of the gastrointestinal tract. In addition, the HLA DQB2 gene has been used as a marker for susceptibility to certain diseases, and genetic variants of the gene have been associated with an increased risk of developing these conditions. In conclusion, the HLA DQB2 gene plays a critical role in the adaptive immune response, and its dysfunction has been linked to several autoimmune and inflammatory diseases. Further research is needed to fully understand the mechanisms by which the HLA DQB2 gene contributes to disease susceptibility and to develop effective therapeutic strategies for treating these conditions.

Genular Protein ID: 817666625

Symbol: DQB2_HUMAN

Name: HLA class II histocompatibility antigen, DQ beta 2 chain

UniProtKB Accession Codes:

P05538 A6NIA5 Q29826 Q29870 Q29871 Q29872 Q29873 Q5SR06

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 8 ExpressionAtlas 1 GO 20 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 2 PathwayCommons 1 PeptideAtlas 1 Pfam 2 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 7 RefSeq 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3036828

Title: Class II genes of the human major histocompatibility complex. Comparisons of the DQ and DX alpha and beta genes.

PubMed ID: 3036828

DOI: 10.1016/s0021-9258(18)47482-0

PubMed ID: 8568858

Title: Evolutionary dynamics of non-coding sequences within the class II region of the human MHC.

PubMed ID: 8568858

DOI: 10.1006/jmbi.1996.0001

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3858830

Title: Gene organization of DC and DX subregions of the human major histocompatibility complex.

PubMed ID: 3858830

DOI: 10.1073/pnas.82.10.3410

PubMed ID: 2564844

Title: Remarkable sequence conservation of the HLA-DQB2 locus (DX beta) within the highly polymorphic DQ subregion of the human MHC.

PubMed ID: 2564844

DOI: 10.1007/bf00717908

PubMed ID: 9036956

Title: The nonpolymorphic MHC class II isotype, HLA-DQA2, is expressed on the surface of B lymphoblastoid cells.

PubMed ID: 9036956

PubMed ID: 11334674

Title: Absence of in vivo DNA-protein interactions in the DQA2 and DQB2 promoter regions.

PubMed ID: 11334674

DOI: 10.1016/s0198-8859(01)00236-1

PubMed ID: 8598037

Title: Invariant chain structure and MHC class II function.

PubMed ID: 8598037

DOI: 10.1016/s0092-8674(00)81025-9

PubMed ID: 11684289

Title: Presentation of antigens by MHC class II molecules: getting the most out of them.

PubMed ID: 11684289

DOI: 10.1016/s0161-5890(01)00069-4

PubMed ID: 18046453

Title: MHC class II molecules on the move for successful antigen presentation.

PubMed ID: 18046453

DOI: 10.1038/sj.emboj.7601945

PubMed ID: 17241953

Title: Autophagy in MHC class II presentation: sampling from within.

PubMed ID: 17241953

DOI: 10.1016/j.immuni.2007.01.005

PubMed ID: 19092054

Title: MHC class II transport at a glance.

PubMed ID: 19092054

DOI: 10.1242/jcs.035089

PubMed ID: 19533806

Title: CD74 in antigen presentation, inflammation, and cancers of the gastrointestinal tract.

PubMed ID: 19533806

DOI: 10.3748/wjg.15.2855

PubMed ID: 22407913

Title: HLA-DQA2 and HLA-DQB2 genes are specifically expressed in human Langerhans cells and encode a new HLA class II molecule.

PubMed ID: 22407913

DOI: 10.4049/jimmunol.1103048

Sequence Information:

  • Length: 268
  • Mass: 30387
  • Checksum: 2746ED6CC5D44AF2
  • Sequence:
    • MSWKMALQIP GGFWAAAVTV MLVMLSTPVA EARDFPKDFL VQFKGMCYFT NGTERVRGVA 
RYIYNREEYG RFDSDVGEFQ AVTELGRSIE DWNNYKDFLE QERAAVDKVC RHNYEAELRT 
TLQRQVEPTV TISPSRTEAL NHHNLLVCSV TDFYPAQIKV RWFRNDQEET AGVVSTSLIR 
NGDWTFQILV MLEITPQRGD IYTCQVEHPS LQSPITVEWR AQSESAQSKM LSGIGGFVLG 
LIFLGLGLII RHRGQKGPRG PPPAGLLH

Genular Protein ID: 1080849774

Symbol: Q5SR05_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5SR05

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 5 GO 5 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 9 MANE-Select 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 264
  • Mass: 29854
  • Checksum: 26E9B8B769A9D55A
  • Sequence:
    • MALQIPGGFW AAAVTVMLVM LSTPVAEARD FPKDFLVQFK GMCYFTNGTE RVRGVARYIY 
NREEYGRFDS DVGEFQAVTE LGRSIEDWNN YKDFLEQERA AVDKVCRHNY EAELRTTLQR 
QVEPTVTISP SRTEALNHHN LLVCSVTDFY PAQIKVRWFR NDQEETAGVV STSLIRNGDW 
TFQILVMLEI TPQRGDIYTC QVEHPSLQSP ITVEWRAQSE SAQSKMLSGI GGFVLGLIFL 
GLGLIIRHRG QKGPRGPPPA GLLH

Genular Protein ID: 2918179020

Symbol: A0A2H4Z4R5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2H4Z4R5

Database IDs:

ARBA 11 AlphaFoldDB 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 15 GO 5 Gene3D 1 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 Pfam 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 219
  • Mass: 25302
  • Checksum: 76F9BEF894C6AAED
  • Sequence:
    • MALQIPGGFW AAAVTVMLVM LSTPVAEARD FPKDFLVQFK GMCYFTNGTE RVRGVARYIY 
NREEYGRFDS DVGEFQAVTE LGRSIEDWNN YKDFLEQERA AVDKVCRHNY EAELRTTLQR 
QVEPTVTISP SRTEALNHHN LLVCSVTDFY PAQIKVRWFR NDQEETAGVV STSLIRNGDW 
TFQILVMLEI TPQRGDIYTC QVEHPSLQSP ITVEWRLLH

Genular Protein ID: 807657653

Symbol: A2ADX3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A2ADX3

Database IDs:

ARBA 11 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 5 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 9 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 3 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 275
  • Mass: 30948
  • Checksum: 6E1A385D96839EE0
  • Sequence:
    • MALQIPGGFW AAAVTVMLVM LSTPVAEARD FPKDFLVQFK GMCYFTNGTE RVRGVARYIY 
NREEYGRFDS DVGEFQAVTE LGRSIEDWNN YKDFLEQERA AVDKVCRHNY EAELRTTLQR 
QVEPTVTISP SRTEALNHHN LLVCSVTDFY PAQIKVRWFR NDQEETAGVV STSLIRNGDW 
TFQILVMLEI TPQRGDIYTC QVEHPSLQSP ITVEWRAQSE SAQSKMLSGI GGFVLGLIFL 
GLGLIIRHRG QKGPRGPPPA GNISAMIQSG ERAQA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.