Details for: HP

Gene ID: 3240

Symbol: HP

Ensembl ID: ENSG00000257017

Description: haptoglobin

Associated with

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 4.71
    Marker Score: 5,049
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 4.21
    Marker Score: 22,610
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 2.74
    Marker Score: 850
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 2.51
    Marker Score: 10,851
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 2.42
    Marker Score: 530
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 2.42
    Marker Score: 15,535
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 2.04
    Marker Score: 770
  • Cell Name: serous secreting cell (CL0000313)
    Fold Change: 2.03
    Marker Score: 809
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 1.85
    Marker Score: 594
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.81
    Marker Score: 498
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: 1.79
    Marker Score: 4,469
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.56
    Marker Score: 2,513
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.39
    Marker Score: 1,395
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 1.35
    Marker Score: 920
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.25
    Marker Score: 849
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 1.22
    Marker Score: 488
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.21
    Marker Score: 878
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 1.16
    Marker Score: 483
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.15
    Marker Score: 4,806
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,812
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,037
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 0.99
    Marker Score: 6,434
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,407
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 505
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 459
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 0.96
    Marker Score: 859
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,412
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.94
    Marker Score: 595
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5,328
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 371
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,740
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 324
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.89
    Marker Score: 11,869
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,296
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.87
    Marker Score: 401
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.78
    Marker Score: 599
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1,266
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 705
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 394
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 458
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 177
  • Cell Name: macrophage (CL0000235)
    Fold Change: 0.67
    Marker Score: 749
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.64
    Marker Score: 1,032
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 0.64
    Marker Score: 16,370
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.56
    Marker Score: 1,999
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.54
    Marker Score: 172
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: 0.54
    Marker Score: 407
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.48
    Marker Score: 745
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.46
    Marker Score: 275
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.45
    Marker Score: 220
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.43
    Marker Score: 24,126
  • Cell Name: myelocyte (CL0002193)
    Fold Change: 0.43
    Marker Score: 186
  • Cell Name: blood cell (CL0000081)
    Fold Change: 0.41
    Marker Score: 4,712
  • Cell Name: promonocyte (CL0000559)
    Fold Change: 0.41
    Marker Score: 261
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.39
    Marker Score: 145
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.39
    Marker Score: 158
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.38
    Marker Score: 93
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.37
    Marker Score: 97
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.35
    Marker Score: 147
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.34
    Marker Score: 239
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: 0.34
    Marker Score: 1,402
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.33
    Marker Score: 425
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.31
    Marker Score: 500
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.31
    Marker Score: 137
  • Cell Name: promyelocyte (CL0000836)
    Fold Change: 0.3
    Marker Score: 150
  • Cell Name: mast cell (CL0000097)
    Fold Change: 0.3
    Marker Score: 175
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: 0.3
    Marker Score: 153
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 0.29
    Marker Score: 6,565
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.29
    Marker Score: 275
  • Cell Name: neutrophil (CL0000775)
    Fold Change: 0.28
    Marker Score: 173
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.28
    Marker Score: 85
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.28
    Marker Score: 362
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.27
    Marker Score: 272
  • Cell Name: Unknown (CL0000003)
    Fold Change: 0.27
    Marker Score: 837
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: 0.27
    Marker Score: 125
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.27
    Marker Score: 134
  • Cell Name: bronchial goblet cell (CL1000312)
    Fold Change: 0.26
    Marker Score: 130
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.26
    Marker Score: 67
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.26
    Marker Score: 178
  • Cell Name: endothelial cell of lymphatic vessel (CL0002138)
    Fold Change: 0.26
    Marker Score: 161
  • Cell Name: tracheobronchial serous cell (CL0019001)
    Fold Change: 0.25
    Marker Score: 91
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.25
    Marker Score: 239
  • Cell Name: intermediate monocyte (CL0002393)
    Fold Change: 0.25
    Marker Score: 85
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.24
    Marker Score: 216
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.24
    Marker Score: 235
  • Cell Name: granulocyte (CL0000094)
    Fold Change: 0.23
    Marker Score: 105
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.23
    Marker Score: 97
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.23
    Marker Score: 3,077
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.23
    Marker Score: 65
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: 0.23
    Marker Score: 227
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.23
    Marker Score: 450
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.22
    Marker Score: 148
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.22
    Marker Score: 75
  • Cell Name: vein endothelial cell (CL0002543)
    Fold Change: 0.21
    Marker Score: 194
  • Cell Name: CD8-positive, alpha-beta T cell (CL0000625)
    Fold Change: 0.21
    Marker Score: 347
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 0.21
    Marker Score: 105
  • Cell Name: innate lymphoid cell (CL0001065)
    Fold Change: 0.2
    Marker Score: 73
  • Cell Name: CD4-positive, alpha-beta T cell (CL0000624)
    Fold Change: 0.2
    Marker Score: 440
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 0.19
    Marker Score: 985

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure and Function:** HP consists of two identical subunits, each with a molecular weight of approximately 15 kDa. It binds to free hemoglobin, forming a 1:1 complex that sequesters it from oxidative damage. 2. **Expression and Regulation:** HP is primarily expressed in the liver, but also in endothelial cells, macrophages, and other cell types involved in immune responses. 3. **Scavenging Mechanism:** HP binds to free hemoglobin through its N-terminal domain, preventing its interaction with oxidative enzymes and subsequent oxidative damage to tissues. 4. **Antioxidant Activity:** HP has been shown to have antioxidant properties, neutralizing reactive oxygen species (ROS) and reducing oxidative stress in tissues. **Pathways and Functions:** 1. **Acute-Phase Response:** HP is upregulated in response to inflammation, serving as a marker of acute-phase response and oxidative stress. 2. **Antioxidant Activity:** HP's antioxidant properties help protect tissues from oxidative damage, modulating the activity of ROS-reducing enzymes. 3. **Immune Response:** HP interacts with scavenger receptors on macrophages, influencing their phagocytic activity and cytokine production. 4. **Hemoglobin Binding:** HP binds to free hemoglobin, preventing its interaction with oxidative enzymes and subsequent oxidative damage to tissues. 5. **Negative Regulation of Oxidative Stress:** HP's binding to hemoglobin reduces oxidative stress, modulating the activity of ROS-reducing enzymes. **Clinical Significance:** Dysregulation of HP has been implicated in various diseases, including: 1. **Hemolytic Uremic Syndrome (HUS):** HP's inability to bind free hemoglobin leads to oxidative damage and inflammation, contributing to HUS. 2. **Cancer:** Altered HP expression and function have been linked to cancer progression and metastasis. 3. **Cardiovascular Disease:** HP's antioxidant properties may protect against cardiovascular disease by reducing oxidative stress and inflammation. 4. **Neurodegenerative Diseases:** HP's role in oxidative stress and inflammation may contribute to the pathogenesis of neurodegenerative diseases, such as Alzheimer's and Parkinson's. In conclusion, haptoglobin plays a multifaceted role in regulating oxidative stress and immune response, making it an important gene in the context of disease pathology. Further research into the mechanisms of HP's function and dysregulation is essential for understanding its clinical significance and developing therapeutic strategies to modulate its activity.

Genular Protein ID: 963343575

Symbol: HPT_HUMAN

Name: Haptoglobin

UniProtKB Accession Codes:

P00738 B0AZL5 P00737 Q0VAC4 Q0VAC5 Q2PP15 Q3B7J0 Q6LBY9 Q9UC67

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CPTAC 3 CTD 1 CarbonylDB 1 ChiTaRS 1 DMDM 1 DNASU 1 DOSAC-COBS-2DPAGE 1 DisGeNET 1 DrugBank 2 EMBL 20 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 4 PIR 2 PRIDE 1 PRINTS 1 PRO 1 PROSITE 2 PROSITE-ProRule 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 2 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SWISS-2DPAGE 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 6688992

Title: Molecular cloning of human haptoglobin cDNA: evidence for a single mRNA coding for alpha 2 and beta chains.

PubMed ID: 6688992

DOI: 10.1002/j.1460-2075.1983.tb01534.x

PubMed ID: 6310599

Title: Identification and characterization of human haptoglobin cDNA.

PubMed ID: 6310599

DOI: 10.1073/pnas.80.19.5875

PubMed ID: 6546723

Title: Characterization of human haptoglobin cDNAs coding for alpha 2FS beta and alpha 1S beta variants.

PubMed ID: 6546723

DOI: 10.1016/0014-5793(84)80215-x

PubMed ID: 6330675

Title: Evolution of haptoglobin: comparison of complementary DNA encoding Hp alpha 1S and Hp alpha 2FS.

PubMed ID: 6330675

DOI: 10.1093/nar/12.11.4531

PubMed ID: 4018023

Title: Structure and expression of the human haptoglobin locus.

PubMed ID: 4018023

DOI: 10.1002/j.1460-2075.1985.tb02325.x

PubMed ID: 2987228

Title: Nucleotide sequence of the haptoglobin and haptoglobin-related gene pair. The haptoglobin-related gene contains a retrovirus-like element.

PubMed ID: 2987228

DOI: 10.1016/s0021-9258(18)88836-6

PubMed ID: 1478675

Title: Junctions between genes in the haptoglobin gene cluster of primates.

PubMed ID: 1478675

DOI: 10.1016/s0888-7543(05)80116-8

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3519135

Title: Expression of cloned human haptoglobin and alpha 1-antitrypsin complementary DNAs in Saccharomyces cerevisiae.

PubMed ID: 3519135

DOI: 10.1089/dna.1986.5.129

PubMed ID: 6310515

Title: Sequence of human haptoglobin cDNA: evidence that the alpha and beta subunits are coded by the same mRNA.

PubMed ID: 6310515

DOI: 10.1093/nar/11.17.5811

PubMed ID: 10493829

Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

PubMed ID: 10493829

DOI: 10.1006/geno.1999.5927

PubMed ID: 6325933

Title: Duplication within the haptoglobin Hp2 gene.

PubMed ID: 6325933

DOI: 10.1038/309131a0

PubMed ID: 6997877

Title: Covalent structure of human haptoglobin: a serine protease homolog.

PubMed ID: 6997877

DOI: 10.1073/pnas.77.6.3388

PubMed ID: 7637327

Title: Protein analysis of human maculae in relation to age-related maculopathy.

PubMed ID: 7637327

PubMed ID: 4573324

Title: Studies on the interchain disulfides of human haptoglobins.

PubMed ID: 4573324

DOI: 10.1139/o73-032

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 14760718

Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.

PubMed ID: 14760718

DOI: 10.1002/pmic.200300556

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19838169

Title: Enrichment of glycopeptides for glycan structure and attachment site identification.

PubMed ID: 19838169

DOI: 10.1038/nmeth.1392

PubMed ID: 19805376

Title: Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2.

PubMed ID: 19805376

DOI: 10.1073/pnas.0906773106

PubMed ID: 19659435

Title: Haptoglobin: basic and clinical aspects.

PubMed ID: 19659435

DOI: 10.1089/ars.2009.2793

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21248165

Title: Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.

PubMed ID: 21248165

DOI: 10.1152/physrev.00003.2008

PubMed ID: 22905912

Title: Resveratrol-induced changes of the human adipocyte secretion profile.

PubMed ID: 22905912

DOI: 10.1021/pr300539b

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 31142615

Title: The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins.

PubMed ID: 31142615

DOI: 10.1074/jbc.ra119.007435

PubMed ID: 14999562

Title: A novel I247T missense mutation in the haptoglobin 2 beta-chain decreases the expression of the protein and is associated with ahaptoglobinemia.

PubMed ID: 14999562

DOI: 10.1007/s00439-004-1098-6

Sequence Information:

  • Length: 406
  • Mass: 45205
  • Checksum: A98B56B2B1BE891E
  • Sequence:
    • MSALGAVIAL LLWGQLFAVD SGNDVTDIAD DGCPKPPEIA HGYVEHSVRY QCKNYYKLRT 
EGDGVYTLND KKQWINKAVG DKLPECEADD GCPKPPEIAH GYVEHSVRYQ CKNYYKLRTE 
GDGVYTLNNE KQWINKAVGD KLPECEAVCG KPKNPANPVQ RILGGHLDAK GSFPWQAKMV 
SHHNLTTGAT LINEQWLLTT AKNLFLNHSE NATAKDIAPT LTLYVGKKQL VEIEKVVLHP 
NYSQVDIGLI KLKQKVSVNE RVMPICLPSK DYAEVGRVGY VSGWGRNANF KFTDHLKYVM 
LPVADQDQCI RHYEGSTVPE KKTPKSPVGV QPILNEHTFC AGMSKYQEDT CYGDAGSAFA 
VHDLEEDTWY ATGILSFDKS CAVAEYGVYV KVTSIQDWVQ KTIAEN

Genular Protein ID: 653375965

Symbol: A0A0C4DGL8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DGL8

Database IDs:

ARBA 3 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 2 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 7 MEROPS 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 347
  • Mass: 38452
  • Checksum: C3A92A17BD401718
  • Sequence:
    • MSALGAVIAL LLWGQLFAVD SGNDVTDIAD DGCPKPPEIA HGYVEHSVRY QCKNYYKLRT 
EGDGVYTLND KKQWINKAVG DKLPECEAVC GKPKNPANPV QRILGGHLDA KGSFPWQAKM 
VSHHNLTTGA TLINEQWLLT TAKNLFLNHS ENATAKDIAP TLTLYVGKKQ LVEIEKVVLH 
PNYSQVDIGL IKLKQKVSVN ERVMPICLPS KDYAEVGRVG YVSGWGRNAN FKFTDHLKYV 
MLPVADQDQC IRHYEGSTVP EKKTPKSPVG VQPILNEHTF CAGMSKYQED TCYGDAGSAF 
AVHDLEEDTW YATGILSFDK SCAVAEYGVY VKVTSIQDWV QKTIAEN

Genular Protein ID: 1625413079

Symbol: Q6PEJ8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6PEJ8

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 GO 2 Gene3D 1 GenomeRNAi 1 InterPro 4 KEGG 1 MEROPS 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 3 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 228
  • Mass: 25458
  • Checksum: 82D0E68C4584E8E9
  • Sequence:
    • MVSHHNLTTG ATLINEQWLL TTAKNLFLNH SENATAKDIA PTLTLYVGKK QLVEIEKVVL 
HPNYSQVDIG LIKLKQKVSV NERVMPICLP SKDYAEVGRV GYVSGWGRNA NFKFTDHLKY 
VMLPVADQDQ CIRHYEGSTV PEKKTPKSPV GVQPILNEHT FCAGMSKYQE DTCYGDAGSA 
FAVHDLEEDT WYATGILSFD KSCAVAEYGV YVKVTSIQDW VQKTIAEN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.