Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: liver dendritic cell (CL2000055)
Fold Change: 183.6047
Cell Significance Index: 484.3400 - Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 55.3537
Cell Significance Index: -8.6100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 7.5203
Cell Significance Index: 126.6800 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 6.9913
Cell Significance Index: -8.6200 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 5.4612
Cell Significance Index: 14.6300 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 3.0886
Cell Significance Index: 10.7500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 3.0612
Cell Significance Index: 98.0500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 2.9058
Cell Significance Index: 42.8900 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 2.3697
Cell Significance Index: 25.9200 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.1211
Cell Significance Index: -8.3700 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 1.9489
Cell Significance Index: 7.3400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.9306
Cell Significance Index: 41.8300 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 1.7657
Cell Significance Index: 13.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.7203
Cell Significance Index: 341.3900 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.6523
Cell Significance Index: 9.5200 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 1.6329
Cell Significance Index: 16.1100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 1.2677
Cell Significance Index: 959.5400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5398
Cell Significance Index: 102.7300 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.3454
Cell Significance Index: 5.8100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.3038
Cell Significance Index: 6.4700 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.2735
Cell Significance Index: 2.6000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2723
Cell Significance Index: 26.9400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2670
Cell Significance Index: 16.0300 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2252
Cell Significance Index: 24.4900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2175
Cell Significance Index: 196.3900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1611
Cell Significance Index: 26.2000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0737
Cell Significance Index: 5.1000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0366
Cell Significance Index: 1.0200 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0103
Cell Significance Index: 0.1600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0021
Cell Significance Index: 1.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0044
Cell Significance Index: -8.2000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0060
Cell Significance Index: -0.3700 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.0068
Cell Significance Index: -0.1300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0069
Cell Significance Index: -12.7900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0084
Cell Significance Index: -12.9400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0096
Cell Significance Index: -13.0100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0102
Cell Significance Index: -0.3600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0115
Cell Significance Index: -0.3300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0142
Cell Significance Index: -10.4300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0160
Cell Significance Index: -10.1900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0170
Cell Significance Index: -12.6200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0190
Cell Significance Index: -10.6900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0204
Cell Significance Index: -2.6100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0208
Cell Significance Index: -0.5200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0225
Cell Significance Index: -1.1400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0228
Cell Significance Index: -10.3500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0231
Cell Significance Index: -8.3000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0254
Cell Significance Index: -7.3000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0280
Cell Significance Index: -1.2700 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0281
Cell Significance Index: -1.1500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0284
Cell Significance Index: -3.3100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0322
Cell Significance Index: -0.8300 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.0352
Cell Significance Index: -0.5000 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0426
Cell Significance Index: -8.5400 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.0476
Cell Significance Index: -0.6600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0537
Cell Significance Index: -11.3200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0541
Cell Significance Index: -9.7600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0628
Cell Significance Index: -6.4200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0636
Cell Significance Index: -8.7400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0699
Cell Significance Index: -10.1600 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.0708
Cell Significance Index: -0.7300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0715
Cell Significance Index: -5.4900 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0737
Cell Significance Index: -1.5000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0748
Cell Significance Index: -12.7700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0765
Cell Significance Index: -9.8800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0818
Cell Significance Index: -10.0600 - Cell Name: inflammatory macrophage (CL0000863)
Fold Change: -0.0833
Cell Significance Index: -0.6400 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0836
Cell Significance Index: -1.2600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0883
Cell Significance Index: -10.1200 - Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0994
Cell Significance Index: -1.0900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1052
Cell Significance Index: -4.9100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1143
Cell Significance Index: -5.3700 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1147
Cell Significance Index: -2.4000 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1224
Cell Significance Index: -1.3900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1265
Cell Significance Index: -7.9700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1322
Cell Significance Index: -8.1300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1394
Cell Significance Index: -10.3900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1419
Cell Significance Index: -9.5400 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.1508
Cell Significance Index: -2.1900 - Cell Name: alveolar macrophage (CL0000583)
Fold Change: -0.1521
Cell Significance Index: -1.3400 - Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
Fold Change: -0.1539
Cell Significance Index: -2.1600 - Cell Name: stromal cell of endometrium (CL0002255)
Fold Change: -0.1582
Cell Significance Index: -2.2500 - Cell Name: pulmonary alveolar type 2 cell (CL0002063)
Fold Change: -0.1608
Cell Significance Index: -1.3300 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.1693
Cell Significance Index: -9.5000 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1706
Cell Significance Index: -3.3300 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.1718
Cell Significance Index: -1.1600 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1810
Cell Significance Index: -11.6800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1899
Cell Significance Index: -9.9700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.1956
Cell Significance Index: -7.1800 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.1981
Cell Significance Index: -2.5400 - Cell Name: Kupffer cell (CL0000091)
Fold Change: -0.1989
Cell Significance Index: -1.8200 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.2024
Cell Significance Index: -1.0600 - Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
Fold Change: -0.2100
Cell Significance Index: -2.1800 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.2180
Cell Significance Index: -2.3700 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.2192
Cell Significance Index: -5.3100 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.2327
Cell Significance Index: -2.9800 - Cell Name: retinal astrocyte (CL4033015)
Fold Change: -0.2340
Cell Significance Index: -2.2900 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.2351
Cell Significance Index: -3.1700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2450
Cell Significance Index: -10.8400 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.2550
Cell Significance Index: -3.7300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 963343575
Symbol: HPT_HUMAN
Name: Haptoglobin
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 6688992
Title: Molecular cloning of human haptoglobin cDNA: evidence for a single mRNA coding for alpha 2 and beta chains.
PubMed ID: 6688992
PubMed ID: 6310599
Title: Identification and characterization of human haptoglobin cDNA.
PubMed ID: 6310599
PubMed ID: 6546723
Title: Characterization of human haptoglobin cDNAs coding for alpha 2FS beta and alpha 1S beta variants.
PubMed ID: 6546723
PubMed ID: 6330675
Title: Evolution of haptoglobin: comparison of complementary DNA encoding Hp alpha 1S and Hp alpha 2FS.
PubMed ID: 6330675
PubMed ID: 4018023
Title: Structure and expression of the human haptoglobin locus.
PubMed ID: 4018023
PubMed ID: 2987228
Title: Nucleotide sequence of the haptoglobin and haptoglobin-related gene pair. The haptoglobin-related gene contains a retrovirus-like element.
PubMed ID: 2987228
PubMed ID: 1478675
Title: Junctions between genes in the haptoglobin gene cluster of primates.
PubMed ID: 1478675
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3519135
Title: Expression of cloned human haptoglobin and alpha 1-antitrypsin complementary DNAs in Saccharomyces cerevisiae.
PubMed ID: 3519135
PubMed ID: 6310515
Title: Sequence of human haptoglobin cDNA: evidence that the alpha and beta subunits are coded by the same mRNA.
PubMed ID: 6310515
PubMed ID: 10493829
Title: Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.
PubMed ID: 10493829
PubMed ID: 6325933
PubMed ID: 6997877
Title: Covalent structure of human haptoglobin: a serine protease homolog.
PubMed ID: 6997877
PubMed ID: 7637327
Title: Protein analysis of human maculae in relation to age-related maculopathy.
PubMed ID: 7637327
PubMed ID: 4573324
Title: Studies on the interchain disulfides of human haptoglobins.
PubMed ID: 4573324
DOI: 10.1139/o73-032
PubMed ID: 12754519
Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.
PubMed ID: 12754519
DOI: 10.1038/nbt827
PubMed ID: 14760718
Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
PubMed ID: 14760718
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 16740002
Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.
PubMed ID: 16740002
DOI: 10.1021/pr050492k
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 19838169
Title: Enrichment of glycopeptides for glycan structure and attachment site identification.
PubMed ID: 19838169
DOI: 10.1038/nmeth.1392
PubMed ID: 19805376
Title: Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2.
PubMed ID: 19805376
PubMed ID: 19659435
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21248165
Title: Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer.
PubMed ID: 21248165
PubMed ID: 22905912
Title: Resveratrol-induced changes of the human adipocyte secretion profile.
PubMed ID: 22905912
DOI: 10.1021/pr300539b
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 31142615
Title: The E3 ubiquitin ligase MARCH2 regulates ERGIC3-dependent trafficking of secretory proteins.
PubMed ID: 31142615
PubMed ID: 14999562
Title: A novel I247T missense mutation in the haptoglobin 2 beta-chain decreases the expression of the protein and is associated with ahaptoglobinemia.
PubMed ID: 14999562
Sequence Information:
- Length: 406
- Mass: 45205
- Checksum: A98B56B2B1BE891E
- Sequence:
MSALGAVIAL LLWGQLFAVD SGNDVTDIAD DGCPKPPEIA HGYVEHSVRY QCKNYYKLRT EGDGVYTLND KKQWINKAVG DKLPECEADD GCPKPPEIAH GYVEHSVRYQ CKNYYKLRTE GDGVYTLNNE KQWINKAVGD KLPECEAVCG KPKNPANPVQ RILGGHLDAK GSFPWQAKMV SHHNLTTGAT LINEQWLLTT AKNLFLNHSE NATAKDIAPT LTLYVGKKQL VEIEKVVLHP NYSQVDIGLI KLKQKVSVNE RVMPICLPSK DYAEVGRVGY VSGWGRNANF KFTDHLKYVM LPVADQDQCI RHYEGSTVPE KKTPKSPVGV QPILNEHTFC AGMSKYQEDT CYGDAGSAFA VHDLEEDTWY ATGILSFDKS CAVAEYGVYV KVTSIQDWVQ KTIAEN
Genular Protein ID: 653375965
Symbol: A0A0C4DGL8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 347
- Mass: 38452
- Checksum: C3A92A17BD401718
- Sequence:
MSALGAVIAL LLWGQLFAVD SGNDVTDIAD DGCPKPPEIA HGYVEHSVRY QCKNYYKLRT EGDGVYTLND KKQWINKAVG DKLPECEAVC GKPKNPANPV QRILGGHLDA KGSFPWQAKM VSHHNLTTGA TLINEQWLLT TAKNLFLNHS ENATAKDIAP TLTLYVGKKQ LVEIEKVVLH PNYSQVDIGL IKLKQKVSVN ERVMPICLPS KDYAEVGRVG YVSGWGRNAN FKFTDHLKYV MLPVADQDQC IRHYEGSTVP EKKTPKSPVG VQPILNEHTF CAGMSKYQED TCYGDAGSAF AVHDLEEDTW YATGILSFDK SCAVAEYGVY VKVTSIQDWV QKTIAEN
Genular Protein ID: 1625413079
Symbol: Q6PEJ8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 228
- Mass: 25458
- Checksum: 82D0E68C4584E8E9
- Sequence:
MVSHHNLTTG ATLINEQWLL TTAKNLFLNH SENATAKDIA PTLTLYVGKK QLVEIEKVVL HPNYSQVDIG LIKLKQKVSV NERVMPICLP SKDYAEVGRV GYVSGWGRNA NFKFTDHLKY VMLPVADQDQ CIRHYEGSTV PEKKTPKSPV GVQPILNEHT FCAGMSKYQE DTCYGDAGSA FAVHDLEEDT WYATGILSFD KSCAVAEYGV YVKVTSIQDW VQKTIAEN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.