Details for: HRH2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 105.6284
Cell Significance Index: -16.4300 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 64.1452
Cell Significance Index: -16.2700 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 34.7132
Cell Significance Index: -14.1000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 33.6518
Cell Significance Index: -17.3100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 14.8679
Cell Significance Index: -14.2000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.3338
Cell Significance Index: -16.4400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 3.6058
Cell Significance Index: 115.4900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 3.3344
Cell Significance Index: 147.4900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 2.8756
Cell Significance Index: 108.8900 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.9895
Cell Significance Index: 30.7800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 1.9072
Cell Significance Index: 16.0200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 1.8642
Cell Significance Index: -4.0800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.8346
Cell Significance Index: 368.0100 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 1.7576
Cell Significance Index: 47.0200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.2772
Cell Significance Index: 243.0500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.2672
Cell Significance Index: 57.4400 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.9295
Cell Significance Index: 17.1800 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.7694
Cell Significance Index: 59.0400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6968
Cell Significance Index: 41.8300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.5988
Cell Significance Index: 414.1300 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 0.5956
Cell Significance Index: 7.9500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4719
Cell Significance Index: 46.6900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4487
Cell Significance Index: 48.8100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4442
Cell Significance Index: 401.1100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4187
Cell Significance Index: 150.2000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.3205
Cell Significance Index: 19.7000 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.3188
Cell Significance Index: 6.9800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2786
Cell Significance Index: 45.3100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2454
Cell Significance Index: 7.0700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2429
Cell Significance Index: 16.8000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.1798
Cell Significance Index: 11.6000 - Cell Name: pro-T cell (CL0000827)
Fold Change: 0.1648
Cell Significance Index: 4.2100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.1374
Cell Significance Index: 3.9200 - Cell Name: myometrial cell (CL0002366)
Fold Change: 0.1302
Cell Significance Index: 1.5000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0624
Cell Significance Index: 1.5600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0324
Cell Significance Index: 6.4200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0208
Cell Significance Index: 0.7300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0188
Cell Significance Index: 8.5200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0042
Cell Significance Index: 0.1000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.0041
Cell Significance Index: 0.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0072
Cell Significance Index: -13.6000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0085
Cell Significance Index: -15.7400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0100
Cell Significance Index: -13.5800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0116
Cell Significance Index: -17.7900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0142
Cell Significance Index: -1.4500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0166
Cell Significance Index: -0.3600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0187
Cell Significance Index: -13.7400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0192
Cell Significance Index: -8.4800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0237
Cell Significance Index: -15.0800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0238
Cell Significance Index: -18.0400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0253
Cell Significance Index: -18.7700 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0270
Cell Significance Index: -0.2200 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0283
Cell Significance Index: -15.4300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0293
Cell Significance Index: -0.8200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0320
Cell Significance Index: -20.0100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0330
Cell Significance Index: -18.6200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0364
Cell Significance Index: -2.2300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0519
Cell Significance Index: -14.9400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0628
Cell Significance Index: -1.2600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0736
Cell Significance Index: -13.2600 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.0743
Cell Significance Index: -0.8200 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0754
Cell Significance Index: -1.8800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0788
Cell Significance Index: -5.3000 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0798
Cell Significance Index: -2.5400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0821
Cell Significance Index: -11.2800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0870
Cell Significance Index: -11.1500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0888
Cell Significance Index: -18.7000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0889
Cell Significance Index: -2.9100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0907
Cell Significance Index: -13.1900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1082
Cell Significance Index: -13.3000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1117
Cell Significance Index: -19.0700 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1205
Cell Significance Index: -5.2400 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.1248
Cell Significance Index: -1.6000 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1345
Cell Significance Index: -2.6600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1350
Cell Significance Index: -17.4400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1399
Cell Significance Index: -16.3000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1454
Cell Significance Index: -10.2800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1457
Cell Significance Index: -17.1800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1564
Cell Significance Index: -16.2900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1609
Cell Significance Index: -18.4300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.1844
Cell Significance Index: -9.5800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1850
Cell Significance Index: -3.9400 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1914
Cell Significance Index: -10.0500 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1997
Cell Significance Index: -2.8600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2005
Cell Significance Index: -15.8800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.2166
Cell Significance Index: -4.6800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2232
Cell Significance Index: -7.8200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2315
Cell Significance Index: -17.2500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2436
Cell Significance Index: -13.6700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2502
Cell Significance Index: -13.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2575
Cell Significance Index: -12.1000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.2674
Cell Significance Index: -4.0300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.2677
Cell Significance Index: -3.3200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2758
Cell Significance Index: -17.3800 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.2974
Cell Significance Index: -3.2400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3443
Cell Significance Index: -8.8500 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: -0.3610
Cell Significance Index: -3.6200 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.3628
Cell Significance Index: -7.1400 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.3647
Cell Significance Index: -7.1300 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.3743
Cell Significance Index: -4.9900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2963209348
Symbol: HRH2_HUMAN
Name: Histamine H2 receptor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1714721
Title: Molecular cloning of the human histamine H2 receptor.
PubMed ID: 1714721
PubMed ID: 7755641
Title: Identification of the promoter region of the human histamine H2-receptor gene.
PubMed ID: 7755641
PubMed ID: 10371214
Title: Human histamine H2 receptor gene: multiple transcription initiation and tissue-specific expression.
PubMed ID: 10371214
PubMed ID: 15014171
Title: Human-specific amino acid changes found in 103 protein-coding genes.
PubMed ID: 15014171
PubMed ID: 19054851
Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.
PubMed ID: 19054851
DOI: 10.1038/nmeth.1273
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8817552
Title: Allelic variations of the human histamine H2 receptor gene.
PubMed ID: 8817552
PubMed ID: 9374694
Title: Novel insights into histamine H2 receptor biology.
PubMed ID: 9374694
Sequence Information:
- Length: 359
- Mass: 40098
- Checksum: 9835AE2BA60B9B0F
- Sequence:
MAPNGTASSF CLDSTACKIT ITVVLAVLIL ITVAGNVVVC LAVGLNRRLR NLTNCFIVSL AITDLLLGLL VLPFSAIYQL SCKWSFGKVF CNIYTSLDVM LCTASILNLF MISLDRYCAV MDPLRYPVLV TPVRVAISLV LIWVISITLS FLSIHLGWNS RNETSKGNHT TSKCKVQVNE VYGLVDGLVT FYLPLLIMCI TYYRIFKVAR DQAKRINHIS SWKAATIREH KATVTLAAVM GAFIICWFPY FTAFVYRGLR GDDAINEVLE AIVLWLGYAN SALNPILYAA LNRDFRTGYQ QLFCCRLANR NSHKTSLRSN ASQLSRTQSR EPRQQEEKPL KLQVWSGTEV TAPQGATDR
Genular Protein ID: 2166581906
Symbol: A0A1B0GTK7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 422
- Mass: 46948
- Checksum: 838678E91AB412D1
- Sequence:
MAPNGTASSF CLDSTACKIT ITVVLAVLIL ITVAGNVVVC LAVGLNRRLR NLTNCFIVSL AITDLLLGLL VLPFSAIYQL SCKWSFGKVF CNIYTSLDVM LCTASILNLF MISLDRYCAV MDPLRYPVLV TPVRVAISLV LIWVISITLS FLSIHLGWNS RNETSKGNHT TSKCKVQVNE VYGLVDGLVT FYLPLLIMCI TYYRIFKVAR DQAKRINHIS SWKAATIREH KATVTLAAVM GAFIICWFPY FTAFVYRGLR GDDAINEVLE AIVLWLGYAN SALNPILYAA LNRDFRTGYQ QLFCCRLANR NSHKTSLRSN ASQLSRTQSR EPRQQEEKPL KLQVWSGTEV TAPQGATDRK PALSCTTCSS NLLSCCKSLW GLRFLQRHMG GPSEELSGEP LSEEPQKRPP QKAVRTLPSE AV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.