Details for: IL2RA

Gene ID: 3559

Symbol: IL2RA

Ensembl ID: ENSG00000134460

Description: interleukin 2 receptor subunit alpha

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 65.1900
    Cell Significance Index: -10.1400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 38.7552
    Cell Significance Index: -9.8300
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 21.7350
    Cell Significance Index: -8.8300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.2079
    Cell Significance Index: -10.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 4.5327
    Cell Significance Index: 133.1200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.7935
    Cell Significance Index: -8.5800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.7864
    Cell Significance Index: 43.1100
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 1.2277
    Cell Significance Index: 12.3100
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: 1.0122
    Cell Significance Index: 17.3900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.2391
    Cell Significance Index: 5.1100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1972
    Cell Significance Index: 3.3800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0477
    Cell Significance Index: 32.9700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0035
    Cell Significance Index: -6.6400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0061
    Cell Significance Index: -11.3000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0066
    Cell Significance Index: -0.1700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0070
    Cell Significance Index: -10.7900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0080
    Cell Significance Index: -1.3600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0099
    Cell Significance Index: -13.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0114
    Cell Significance Index: -7.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0143
    Cell Significance Index: -10.6000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0156
    Cell Significance Index: -11.8100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0175
    Cell Significance Index: -9.8500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0188
    Cell Significance Index: -6.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0198
    Cell Significance Index: -10.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0204
    Cell Significance Index: -9.2500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0249
    Cell Significance Index: -4.9500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0253
    Cell Significance Index: -5.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0304
    Cell Significance Index: -8.7500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0367
    Cell Significance Index: -5.3300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0379
    Cell Significance Index: -6.8300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0399
    Cell Significance Index: -5.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0418
    Cell Significance Index: -4.9300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0505
    Cell Significance Index: -10.6400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0655
    Cell Significance Index: -2.8500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0663
    Cell Significance Index: -8.1600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0665
    Cell Significance Index: -6.8000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0770
    Cell Significance Index: -10.5800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0779
    Cell Significance Index: -10.0600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0873
    Cell Significance Index: -10.0000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0969
    Cell Significance Index: -10.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1073
    Cell Significance Index: -3.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1248
    Cell Significance Index: -9.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1374
    Cell Significance Index: -10.2400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1420
    Cell Significance Index: -9.1600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1530
    Cell Significance Index: -10.2900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1562
    Cell Significance Index: -7.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1642
    Cell Significance Index: -10.3500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1716
    Cell Significance Index: -8.9400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1723
    Cell Significance Index: -10.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1793
    Cell Significance Index: -8.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1965
    Cell Significance Index: -12.0500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2124
    Cell Significance Index: -11.9200
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: -0.2170
    Cell Significance Index: -2.2500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2216
    Cell Significance Index: -11.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2353
    Cell Significance Index: -10.4100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2597
    Cell Significance Index: -9.1000
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2673
    Cell Significance Index: -2.1800
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.2705
    Cell Significance Index: -3.6500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.2765
    Cell Significance Index: -11.3300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2773
    Cell Significance Index: -10.5000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2850
    Cell Significance Index: -9.3300
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.2910
    Cell Significance Index: -3.1900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.2923
    Cell Significance Index: -7.0800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2931
    Cell Significance Index: -9.3400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3064
    Cell Significance Index: -8.2000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3090
    Cell Significance Index: -9.1000
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.3118
    Cell Significance Index: -4.5600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3157
    Cell Significance Index: -8.4600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.3203
    Cell Significance Index: -4.2700
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.3228
    Cell Significance Index: -1.7600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3285
    Cell Significance Index: -4.7100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3339
    Cell Significance Index: -15.5700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3401
    Cell Significance Index: -9.7500
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.3420
    Cell Significance Index: -4.2300
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.3428
    Cell Significance Index: -5.9100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3435
    Cell Significance Index: -12.0700
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.3456
    Cell Significance Index: -5.8700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3544
    Cell Significance Index: -13.0100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3593
    Cell Significance Index: -9.7800
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3645
    Cell Significance Index: -9.0900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3652
    Cell Significance Index: -9.3300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3719
    Cell Significance Index: -9.9300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3785
    Cell Significance Index: -10.8000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3791
    Cell Significance Index: -11.9900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3820
    Cell Significance Index: -9.5300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3980
    Cell Significance Index: -10.1400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4087
    Cell Significance Index: -8.9500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.4168
    Cell Significance Index: -12.0100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4288
    Cell Significance Index: -9.1000
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.4341
    Cell Significance Index: -5.1200
  • Cell Name: CD4-positive, alpha-beta memory T cell (CL0000897)
    Fold Change: -0.4354
    Cell Significance Index: -4.1900
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.4370
    Cell Significance Index: -3.7800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4374
    Cell Significance Index: -9.4500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4581
    Cell Significance Index: -9.5600
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.4635
    Cell Significance Index: -5.4500
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.4651
    Cell Significance Index: -6.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4710
    Cell Significance Index: -9.4600
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.4749
    Cell Significance Index: -5.4400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4783
    Cell Significance Index: -11.4700
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.4804
    Cell Significance Index: -9.7800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IL2RA is a non-covalently associated subunit of the IL-2 receptor complex, which is composed of three subunits: alpha, beta, and gamma. The alpha subunit is the most relevant for this discussion, as it is the primary binding site for IL-2. IL2RA is a type I transmembrane protein, with a hydrophobic transmembrane domain and a cytoplasmic tail that interacts with the IL-2 receptor gamma chain. The alpha subunit is also capable of dimerization, which can modulate its activity and affinity for IL-2. IL2RA is expressed on the surface of various cell types, including CD4+ T cells, CD45RO+ memory T cells, and other immune cells such as dendritic cells, natural killer cells, and epithelial cells. The expression of IL2RA is tightly regulated and is often restricted to the early stages of T cell development, where it plays a critical role in the activation and proliferation of naive T cells. **Pathways and Functions** IL2RA plays a central role in the regulation of T cell responses, particularly in the activation and proliferation of CD4+ T cells. The IL-2 receptor complex formed by IL2RA, IL-2 receptor beta, and IL-2 receptor gamma chains is activated by binding of IL-2 to the alpha subunit. This binding triggers a cascade of signaling events that ultimately lead to the activation of transcription factors, such as NF-κB and STAT5, which drive the expression of genes involved in T cell proliferation, differentiation, and survival. IL2RA also plays a role in the regulation of T cell homeostasis, tolerance, and differentiation. The IL-2 receptor complex is involved in the regulation of T cell proliferation and differentiation, particularly in the early stages of T cell development. IL2RA is also required for the induction of regulatory T cells (Tregs), which play a crucial role in maintaining immune tolerance and preventing autoimmune disease. **Clinical Significance** Dysregulation of IL2RA has been implicated in various immune-related disorders, including autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, and type 1 diabetes. Elevated levels of IL2RA have been observed in patients with chronic inflammatory diseases, such as psoriasis and Crohn's disease. Additionally, IL2RA has been targeted as a potential therapeutic strategy for the treatment of cancer, where it is involved in the regulation of T cell responses and tumor immunity. Furthermore, IL2RA has been used as a biomarker for monitoring the efficacy of immunosuppressive therapies in patients with autoimmune diseases. The expression of IL2RA is often reduced in patients with chronic immune activation, and elevated levels of IL2RA have been correlated with disease activity and poor treatment outcomes. In conclusion, IL2RA is a critical component of the IL-2 receptor complex, which plays a pivotal role in the regulation of T cell responses. Its dysregulation has been implicated in various immune-related disorders, and it has potential therapeutic applications in the treatment of autoimmune diseases and cancer.

Genular Protein ID: 2323127

Symbol: IL2RA_HUMAN

Name: Interleukin-2 receptor subunit alpha

UniProtKB Accession Codes:

P01589 Q5W007

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 6 DrugCentral 1 EMBL 24 EMDB 1 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 4 RefSeq 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 6090949

Title: Molecular cloning of cDNA encoding human interleukin-2 receptor.

PubMed ID: 6090949

DOI: 10.1038/311631a0

PubMed ID: 6090948

Title: Molecular cloning and expression of cDNAs for the human interleukin-2 receptor.

PubMed ID: 6090948

DOI: 10.1038/311626a0

PubMed ID: 2999698

Title: Molecular cloning and structure of the human interleukin 2 receptor gene.

PubMed ID: 2999698

DOI: 10.1093/nar/13.21.7579

PubMed ID: 2996141

Title: Structure of the human interleukin-2 receptor gene.

PubMed ID: 2996141

DOI: 10.1126/science.2996141

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 3030566

Title: Regulation of the human interleukin-2 receptor alpha chain promoter: activation of a nonfunctional promoter by the transactivator gene of HTLV-I.

PubMed ID: 3030566

DOI: 10.1016/0092-8674(87)90754-9

PubMed ID: 3134887

Title: Structural analysis of recombinant soluble human interleukin-2 receptor. Primary structure, assignment of disulfide bonds and core IL-2 binding structure.

PubMed ID: 3134887

DOI: 10.1016/0006-291x(88)90695-x

PubMed ID: 7529123

Title: The interleukin-2 and interleukin-4 receptors studied by molecular modelling.

PubMed ID: 7529123

DOI: 10.1016/s0969-2126(94)00085-9

PubMed ID: 16293754

Title: Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors.

PubMed ID: 16293754

DOI: 10.1126/science.1117893

PubMed ID: 16477002

Title: Crystal structure of the IL-2 signaling complex: paradigm for a heterotrimeric cytokine receptor.

PubMed ID: 16477002

DOI: 10.1073/pnas.0511161103

PubMed ID: 17676041

Title: Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

PubMed ID: 17676041

DOI: 10.1038/ng2102

PubMed ID: 23416241

Title: Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity.

PubMed ID: 23416241

DOI: 10.1016/j.clim.2013.01.004

PubMed ID: 24116927

Title: Follicular bronchiolitis as phenotype associated with CD25 deficiency.

PubMed ID: 24116927

DOI: 10.1111/cei.12214

Sequence Information:

  • Length: 272
  • Mass: 30819
  • Checksum: 83D907C8C81D2C0E
  • Sequence:
    • MDSYLLMWGL LTFIMVPGCQ AELCDDDPPE IPHATFKAMA YKEGTMLNCE CKRGFRRIKS 
GSLYMLCTGN SSHSSWDNQC QCTSSATRNT TKQVTPQPEE QKERKTTEMQ SPMQPVDQAS 
LPGHCREPPP WENEATERIY HFVVGQMVYY QCVQGYRALH RGPAESVCKM THGKTRWTQP 
QLICTGEMET SQFPGEEKPQ ASPEGRPESE TSCLVTTTDF QIQTEMAATM ETSIFTTEYQ 
VAVAGCVFLL ISVLLLSGLT WQRRQRKSRR TI

Genular Protein ID: 785125499

Symbol: H0Y5Z0_HUMAN

Name: N/A

UniProtKB Accession Codes:

H0Y5Z0

Database IDs:

ARBA 12 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 2 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 176
  • Mass: 19938
  • Checksum: 436F64DF08882879
  • Sequence:
    • MDSYLLMWGL LTFIMVPGCQ AELCDDDPPE IPHATFKAMA YKEGTMLNCE CKRGFRRIKS 
GSLYMLCTGN SSHSSWDNQC QCTSSATRNT TKQVTPQPEE QKERKTTEMQ SPMQPVDQAS 
LPDFQIQTEM AATMETSIFT TEYQVAVAGC VFLLISVLLL SGLTWQRRQR KSRRTI

Genular Protein ID: 1715763074

Symbol: Q5W005_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5W005

Database IDs:

ARBA 12 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 3 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 Proteomes 2 RefSeq 1 SAM 3 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 200
  • Mass: 22454
  • Checksum: 7793254ABA60CEB6
  • Sequence:
    • MDSYLLMWGL LTFIMVPGCQ AELCDDDPPE IPHATFKAMA YKEGTMLNCE CKRGFRRIKS 
GSLYMLCTGN SSHSSWDNQC QCTSSATRNT TKQVTPQPEE QKERKTTEMQ SPMQPVDQAS 
LPGEEKPQAS PEGRPESETS CLVTTTDFQI QTEMAATMET SIFTTEYQVA VAGCVFLLIS 
VLLLSGLTWQ RRQRKSRRTI

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.