Details for: IL6R

Gene ID: 3570

Symbol: IL6R

Ensembl ID: ENSG00000160712

Description: interleukin 6 receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 133.2088
    Cell Significance Index: -20.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 71.1235
    Cell Significance Index: -18.0400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 48.0238
    Cell Significance Index: -19.5100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 46.4498
    Cell Significance Index: -21.9300
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 42.2057
    Cell Significance Index: -21.7100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.8700
    Cell Significance Index: -20.8000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.1274
    Cell Significance Index: -18.8200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.6155
    Cell Significance Index: -12.2900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 5.5859
    Cell Significance Index: 94.1000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.3218
    Cell Significance Index: -21.0000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.4070
    Cell Significance Index: 32.8400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 2.1830
    Cell Significance Index: 53.2700
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 1.9267
    Cell Significance Index: 35.6100
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 1.9113
    Cell Significance Index: 12.6800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3950
    Cell Significance Index: 37.9700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.2460
    Cell Significance Index: 10.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1965
    Cell Significance Index: 237.4500
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 1.1776
    Cell Significance Index: 19.0000
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.0502
    Cell Significance Index: 12.9900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.9220
    Cell Significance Index: 23.7000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.8294
    Cell Significance Index: 13.9500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.6789
    Cell Significance Index: 87.7100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.6767
    Cell Significance Index: 50.4400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6506
    Cell Significance Index: 18.7500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6155
    Cell Significance Index: 27.9000
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.5788
    Cell Significance Index: 5.9900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5635
    Cell Significance Index: 43.2400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5449
    Cell Significance Index: 32.7100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4514
    Cell Significance Index: 407.5400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.4393
    Cell Significance Index: 9.3900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.4282
    Cell Significance Index: 21.6400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.3997
    Cell Significance Index: 5.9000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3925
    Cell Significance Index: 7.6600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3854
    Cell Significance Index: 8.3500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3737
    Cell Significance Index: 36.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3251
    Cell Significance Index: 35.3600
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 0.3123
    Cell Significance Index: 4.3800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2440
    Cell Significance Index: 11.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.2413
    Cell Significance Index: 5.5800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2275
    Cell Significance Index: 37.0000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2100
    Cell Significance Index: 5.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2020
    Cell Significance Index: 40.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1997
    Cell Significance Index: 13.8100
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 0.1997
    Cell Significance Index: 1.2800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.1849
    Cell Significance Index: 4.9500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.1752
    Cell Significance Index: 2.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1442
    Cell Significance Index: 16.8100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1241
    Cell Significance Index: 67.7600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1232
    Cell Significance Index: 4.3300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1172
    Cell Significance Index: 74.4500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1096
    Cell Significance Index: 20.8600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.1040
    Cell Significance Index: 1.4800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0936
    Cell Significance Index: 2.3400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0650
    Cell Significance Index: 8.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0568
    Cell Significance Index: 107.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0422
    Cell Significance Index: 15.1300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0390
    Cell Significance Index: 6.6600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0313
    Cell Significance Index: 21.6600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0306
    Cell Significance Index: 13.9000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0118
    Cell Significance Index: 0.3100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0003
    Cell Significance Index: 0.0600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.0000
    Cell Significance Index: -0.0200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0036
    Cell Significance Index: -2.7000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0040
    Cell Significance Index: -3.0000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0061
    Cell Significance Index: -3.7900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0095
    Cell Significance Index: -17.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0099
    Cell Significance Index: -4.3600
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0111
    Cell Significance Index: -0.1600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0112
    Cell Significance Index: -17.2800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0143
    Cell Significance Index: -19.4400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0233
    Cell Significance Index: -17.0800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0295
    Cell Significance Index: -3.0100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0329
    Cell Significance Index: -4.5200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0391
    Cell Significance Index: -8.2300
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0400
    Cell Significance Index: -2.0800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0429
    Cell Significance Index: -1.2300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0576
    Cell Significance Index: -2.6900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0650
    Cell Significance Index: -18.6900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0720
    Cell Significance Index: -10.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0933
    Cell Significance Index: -10.6900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1255
    Cell Significance Index: -3.9700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1295
    Cell Significance Index: -14.7900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1360
    Cell Significance Index: -17.4400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1384
    Cell Significance Index: -16.3200
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.1655
    Cell Significance Index: -1.3900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1823
    Cell Significance Index: -18.9900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1883
    Cell Significance Index: -4.0100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2137
    Cell Significance Index: -14.3700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2272
    Cell Significance Index: -14.6600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2448
    Cell Significance Index: -19.3900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2466
    Cell Significance Index: -17.4400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.2504
    Cell Significance Index: -4.4300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2832
    Cell Significance Index: -17.3600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3046
    Cell Significance Index: -8.9500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3444
    Cell Significance Index: -21.1700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3634
    Cell Significance Index: -22.9100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3703
    Cell Significance Index: -19.2900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3850
    Cell Significance Index: -7.7300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3921
    Cell Significance Index: -22.0000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3935
    Cell Significance Index: -20.6600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The IL6R gene exhibits several key characteristics that contribute to its functional importance: 1. **Transmembrane localization**: The IL6R gene encodes a transmembrane receptor, which allows it to interact with IL-6 and transmit signals across the cell membrane. 2. **High expression in immune cells**: The IL6R gene is highly expressed in immune cells, such as monocytes and T-helper 17 cells, indicating its critical role in immune responses. 3. **Tissue-specific expression**: The IL6R gene is expressed in various tissues, including the liver, kidney, and pancreas, highlighting its involvement in multiple organ systems. 4. **Signal transduction**: The IL6R gene is involved in signal transduction pathways, including the JAK/STAT pathway, which regulates gene expression in response to IL-6. **Pathways and Functions** The IL6R gene is involved in several signaling pathways, including: 1. **Acute-phase response**: The IL6R gene plays a key role in the acute-phase response, a systemic response to inflammation and tissue damage. 2. **Cytokine-mediated signaling pathway**: The IL6R gene is involved in cytokine-mediated signaling pathways, including the IL-6/IL-6R/JAK/STAT pathway. 3. **Immune system**: The IL6R gene is critical for the regulation of immune responses, including the activation of T-helper 17 cells and the production of cytokines. 4. **Hematopoiesis**: The IL6R gene is involved in hematopoiesis, the process of blood cell formation. **Clinical Significance** The IL6R gene has significant clinical implications: 1. **Inflammatory disorders**: The IL6R gene is involved in the pathogenesis of inflammatory disorders, including rheumatoid arthritis, lupus, and multiple sclerosis. 2. **Cancer**: The IL6R gene is overexpressed in certain types of cancer, including breast cancer and colon cancer, and is associated with poor prognosis. 3. **Autoimmune diseases**: The IL6R gene is involved in autoimmune diseases, including type 1 diabetes and autoimmune hepatitis. 4. **Viral infections**: The IL6R gene is involved in the regulation of immune responses to viral infections, including SARS-CoV and influenza. In conclusion, the IL6R gene plays a critical role in the regulation of various physiological and pathological processes, including inflammation, immune response, and hematopoiesis. Its clinical significance is evident in the pathogenesis of inflammatory disorders, cancer, autoimmune diseases, and viral infections. Further research is needed to fully elucidate the functions of the IL6R gene and its clinical implications.

Genular Protein ID: 548217405

Symbol: IL6RA_HUMAN

Name: IL-6R 1

UniProtKB Accession Codes:

P08887 A8KAE8 B2R6V4 Q16202 Q53EQ7 Q5FWG2 Q5VZ23

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 4 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 ELM 1 EMBL 9 EMDB 5 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 43 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 6 RefSeq 3 SASBDB 1 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3136546

Title: Cloning and expression of the human interleukin-6 (BSF-2/IFN beta 2) receptor.

PubMed ID: 3136546

DOI: 10.1126/science.3136546

PubMed ID: 1872801

Title: Structural and functional studies on the human hepatic interleukin-6 receptor. Molecular cloning and overexpression in HepG2 cells.

PubMed ID: 1872801

DOI: 10.1042/bj2770659

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8056053

Title: Soluble interleukin-6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism.

PubMed ID: 8056053

DOI: 10.1002/eji.1830240837

PubMed ID: 10066782

Title: Disulfide bond structure and N-glycosylation sites of the extracellular domain of the human interleukin-6 receptor.

PubMed ID: 10066782

DOI: 10.1074/jbc.274.11.7207

PubMed ID: 2529343

Title: Soluble cytokine receptors are present in normal human urine.

PubMed ID: 2529343

DOI: 10.1084/jem.170.4.1409

PubMed ID: 8467812

Title: Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130.

PubMed ID: 8467812

DOI: 10.1002/j.1460-2075.1993.tb05815.x

PubMed ID: 11017875

Title: The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized Madin-Darby canine kidney cells.

PubMed ID: 11017875

DOI: 10.1242/jcs.113.20.3593

PubMed ID: 12794819

Title: Anti-interleukin-6 receptor antibody therapy reduces vascular endothelial growth factor production in rheumatoid arthritis.

PubMed ID: 12794819

DOI: 10.1002/art.11143

PubMed ID: 16270750

Title: Increased association with detergent-resistant membranes/lipid rafts of apically targeted mutants of the interleukin-6 receptor gp80.

PubMed ID: 16270750

DOI: 10.1016/j.ejcb.2005.06.001

PubMed ID: 21990364

Title: Inhibition of classic signaling is a novel function of soluble glycoprotein 130 (sgp130), which is controlled by the ratio of interleukin 6 and soluble interleukin 6 receptor.

PubMed ID: 21990364

DOI: 10.1074/jbc.m111.295758

PubMed ID: 26876177

Title: Proteolytic Cleavage Governs Interleukin-11 Trans-signaling.

PubMed ID: 26876177

DOI: 10.1016/j.celrep.2016.01.053

PubMed ID: 28265003

Title: SorLA in Interleukin-6 Signaling and Turnover.

PubMed ID: 28265003

DOI: 10.1128/mcb.00641-16

PubMed ID: 28060820

Title: Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation.

PubMed ID: 28060820

DOI: 10.1371/journal.pbio.2000080

PubMed ID: 30995492

Title: Targeting Interleukin-6 Signaling in Clinic.

PubMed ID: 30995492

DOI: 10.1016/j.immuni.2019.03.026

PubMed ID: 12461182

Title: Structure of the extracellular domains of the human interleukin-6 receptor alpha-chain.

PubMed ID: 12461182

DOI: 10.1073/pnas.232432399

PubMed ID: 12829785

Title: Hexameric structure and assembly of the interleukin-6/IL-6 alpha-receptor/gp130 complex.

PubMed ID: 12829785

DOI: 10.1126/science.1083901

PubMed ID: 17357077

Title: Admixture mapping of an allele affecting interleukin 6 soluble receptor and interleukin 6 levels.

PubMed ID: 17357077

DOI: 10.1086/513206

PubMed ID: 31235509

Title: Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses.

PubMed ID: 31235509

DOI: 10.1084/jem.20190344

Sequence Information:

  • Length: 468
  • Mass: 51548
  • Checksum: 62AA239FA14F1B8B
  • Sequence:
    • MLAVGCALLA ALLAAPGAAL APRRCPAQEV ARGVLTSLPG DSVTLTCPGV EPEDNATVHW 
VLRKPAAGSH PSRWAGMGRR LLLRSVQLHD SGNYSCYRAG RPAGTVHLLV DVPPEEPQLS 
CFRKSPLSNV VCEWGPRSTP SLTTKAVLLV RKFQNSPAED FQEPCQYSQE SQKFSCQLAV 
PEGDSSFYIV SMCVASSVGS KFSKTQTFQG CGILQPDPPA NITVTAVARN PRWLSVTWQD 
PHSWNSSFYR LRFELRYRAE RSKTFTTWMV KDLQHHCVIH DAWSGLRHVV QLRAQEEFGQ 
GEWSEWSPEA MGTPWTESRS PPAENEVSTP MQALTTNKDD DNILFRDSAN ATSLPVQDSS 
SVPLPTFLVA GGSLAFGTLL CIAIVLRFKK TWKLRALKEG KTSMHPPYSL GQLVPERPRP 
TPVLVPLISP PVSPSSLGSD NTSSHNRPDA RDPRSPYDIS NTDYFFPR

Genular Protein ID: 557958099

Symbol: A0A087WTB5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WTB5

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 11 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 3 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

Sequence Information:

  • Length: 352
  • Mass: 38849
  • Checksum: 7145908AEB117878
  • Sequence:
    • MLAVGCALLA ALLAAPGAAL APRRCPAQEV ARGVLTSLPG DSVTLTCPGV EPEDNATVHW 
VLRKPAAGSH PSRWAGMGRR LLLRSVQLHD SGNYSCYRAG RPAGTVHLLV DVPPEEPQLS 
CFRKSPLSNV VCEWGPRSTP SLTTKAVLLV RKFQNSPAED FQEPCQYSQE SQKFSCQLAV 
PEGDSSFYIV SMCVASSVGS KFSKTQTFQG CGILQPDPPA NITVTAVARN PRWLSVTWQD 
PHSWNSSFYR LRFELRYRAE RSKTFTTWMV KDLQHHCVIH DAWSGLRHVV QLRAQEEFGQ 
GEWSEWSPEA MGTPWTDRLS PRCPGWSTAV QSQLTATSAS WVQAILPPQP PK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.