Details for: IL15RA

Gene ID: 3601

Symbol: IL15RA

Ensembl ID: ENSG00000134470

Description: interleukin 15 receptor subunit alpha

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 56.8323
    Cell Significance Index: -8.8400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 41.3179
    Cell Significance Index: -10.4800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 24.9596
    Cell Significance Index: -10.1400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.8487
    Cell Significance Index: -10.9100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.6103
    Cell Significance Index: -10.0900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.7516
    Cell Significance Index: -10.0500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.8636
    Cell Significance Index: -11.3000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.3442
    Cell Significance Index: -7.2000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.6396
    Cell Significance Index: 312.0300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.3720
    Cell Significance Index: 39.3300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.1527
    Cell Significance Index: 7.8100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.8698
    Cell Significance Index: 12.5100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.7857
    Cell Significance Index: 11.8400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7653
    Cell Significance Index: 45.9500
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.7085
    Cell Significance Index: 6.8300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6790
    Cell Significance Index: 73.8600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.6112
    Cell Significance Index: 30.8900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.5836
    Cell Significance Index: 11.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5376
    Cell Significance Index: 87.4400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.5355
    Cell Significance Index: 9.0200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4145
    Cell Significance Index: 48.3000
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.4060
    Cell Significance Index: 5.8300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3299
    Cell Significance Index: 9.2200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2567
    Cell Significance Index: 17.7500
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.2186
    Cell Significance Index: 1.5700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.2170
    Cell Significance Index: 3.1100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1978
    Cell Significance Index: 19.5700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1972
    Cell Significance Index: 2.6900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1850
    Cell Significance Index: 5.3300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1468
    Cell Significance Index: 4.3100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1434
    Cell Significance Index: 6.7400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1292
    Cell Significance Index: 3.2300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1279
    Cell Significance Index: 16.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0867
    Cell Significance Index: 12.6000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0834
    Cell Significance Index: 2.2700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0810
    Cell Significance Index: 44.2600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0777
    Cell Significance Index: 34.3400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0764
    Cell Significance Index: 13.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0614
    Cell Significance Index: 1.3300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0591
    Cell Significance Index: 11.8700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0537
    Cell Significance Index: 37.1400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0490
    Cell Significance Index: 2.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0468
    Cell Significance Index: 6.4300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0463
    Cell Significance Index: 0.2800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0164
    Cell Significance Index: 0.3500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0152
    Cell Significance Index: 1.8700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0088
    Cell Significance Index: 0.3100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0069
    Cell Significance Index: 0.3200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.0043
    Cell Significance Index: 0.0800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0038
    Cell Significance Index: 3.4100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0024
    Cell Significance Index: 0.2800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0014
    Cell Significance Index: -0.0400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0016
    Cell Significance Index: -0.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0027
    Cell Significance Index: -4.2000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0030
    Cell Significance Index: -5.5700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0044
    Cell Significance Index: -8.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0076
    Cell Significance Index: -10.3900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0093
    Cell Significance Index: -7.0700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0114
    Cell Significance Index: -2.0500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0116
    Cell Significance Index: -4.1500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0130
    Cell Significance Index: -8.2600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0147
    Cell Significance Index: -10.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0200
    Cell Significance Index: -11.2900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0203
    Cell Significance Index: -12.6900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0214
    Cell Significance Index: -9.7100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0243
    Cell Significance Index: -2.4800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0243
    Cell Significance Index: -2.8700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0282
    Cell Significance Index: -8.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0390
    Cell Significance Index: -7.7300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0393
    Cell Significance Index: -5.0400
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0434
    Cell Significance Index: -0.6400
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.0434
    Cell Significance Index: -0.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0528
    Cell Significance Index: -2.7500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0593
    Cell Significance Index: -12.4800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0607
    Cell Significance Index: -1.2600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0699
    Cell Significance Index: -1.8700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0725
    Cell Significance Index: -5.1300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0792
    Cell Significance Index: -6.0800
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.0894
    Cell Significance Index: -1.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0959
    Cell Significance Index: -7.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1091
    Cell Significance Index: -11.3700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1212
    Cell Significance Index: -7.8200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1317
    Cell Significance Index: -2.0900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1398
    Cell Significance Index: -11.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1593
    Cell Significance Index: -10.7100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1680
    Cell Significance Index: -1.3700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1737
    Cell Significance Index: -9.0500
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.1779
    Cell Significance Index: -0.6700
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.1837
    Cell Significance Index: -2.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1895
    Cell Significance Index: -11.6500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1939
    Cell Significance Index: -11.8900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1944
    Cell Significance Index: -10.9100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1978
    Cell Significance Index: -5.3000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2032
    Cell Significance Index: -5.1900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2244
    Cell Significance Index: -11.7800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.2285
    Cell Significance Index: -5.2800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2347
    Cell Significance Index: -7.6900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2391
    Cell Significance Index: -4.9900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2458
    Cell Significance Index: -7.8300
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2502
    Cell Significance Index: -10.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** IL15RA is a transmembrane receptor with a cytoplasmic tail, which is essential for its function. The receptor is composed of two subunits, alpha and gamma, which are encoded by separate genes (IL15RA and IL15RG, respectively). IL15RA is primarily expressed on the surface of cells, where it interacts with the IL-15 ligand to activate the receptor complex. The IL-15 receptor complex is composed of three subunits: IL15RA, IL15RG, and the common gamma chain (γc). IL15RA is responsible for transmitting signals from the IL-15 ligand to downstream signaling pathways, which regulate various cellular processes. **Pathways and Functions** IL15RA is involved in several signaling pathways, including: 1. **JAK-STAT pathway**: IL15RA interacts with the IL-15 ligand to activate the JAK-STAT signaling pathway, which regulates gene expression and cellular responses. 2. **Cytokine signaling**: IL15RA is involved in the regulation of cytokine production, including the production of interferon-gamma (IFN-γ) and interleukin-12 (IL-12) by NK cells. 3. **Natural killer cell differentiation**: IL15RA is essential for the differentiation and activation of NK cells, which play a critical role in the innate immune response. 4. **Phagocytosis**: IL15RA is involved in the regulation of phagocytosis, a process by which immune cells engulf and eliminate pathogens. **Clinical Significance** IL15RA plays a crucial role in various diseases, including: 1. **Cancer**: IL15RA is overexpressed in certain types of cancer, including multiple myeloma and chronic lymphocytic leukemia (CLL), suggesting its potential as a therapeutic target. 2. **Autoimmune diseases**: IL15RA is involved in the regulation of immune responses, and its dysregulation is implicated in autoimmune diseases such as rheumatoid arthritis and lupus. 3. **Infectious diseases**: IL15RA is involved in the regulation of immune responses to infections, and its dysregulation is implicated in the pathogenesis of diseases such as tuberculosis and HIV. 4. **Neurological disorders**: IL15RA is expressed in the central nervous system, and its dysregulation is implicated in neurological disorders such as Alzheimer's disease and Parkinson's disease. In conclusion, IL15RA is a critical component of the IL-15 receptor complex, playing a vital role in the regulation of immune responses and tissue homeostasis. Its dysregulation is implicated in various diseases, including cancer, autoimmune diseases, infectious diseases, and neurological disorders. Further research is needed to fully understand the functions of IL15RA and its potential as a therapeutic target.

Genular Protein ID: 3895243729

Symbol: I15RA_HUMAN

Name: Interleukin-15 receptor subunit alpha

UniProtKB Accession Codes:

Q13261 B4E2C2 Q3B769 Q5JVA1 Q5JVA2 Q5JVA4 Q6B0J2 Q7LDR4 Q7Z609

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEMBL 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PRO 1 PROSITE 1 PathwayCommons 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 RNAct 1 Reactome 1 RefSeq 4 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8530383

Title: Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.

PubMed ID: 8530383

DOI: 10.1074/jbc.270.50.29862

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9110174

Title: Large-scale concatenation cDNA sequencing.

PubMed ID: 9110174

DOI: 10.1101/gr.7.4.353

PubMed ID: 10480910

Title: Natural splicing of exon 2 of human interleukin-15 receptor alpha-chain mRNA results in a shortened form with a distinct pattern of expression.

PubMed ID: 10480910

DOI: 10.1074/jbc.274.38.26978

PubMed ID: 11714793

Title: The IL-15R alpha chain signals through association with Syk in human B cells.

PubMed ID: 11714793

DOI: 10.4049/jimmunol.167.11.6292

PubMed ID: 21289315

Title: The IL-15R alpha chain signals through association with Syk in human B cells.

PubMed ID: 21289315

DOI: 10.4049/jimmunol.1090142

PubMed ID: 12114302

Title: Expression of IL-15 and IL-15 receptor isoforms in select structures of human fetal brain.

PubMed ID: 12114302

DOI: 10.1111/j.1749-6632.2002.tb04245.x

PubMed ID: 15039446

Title: Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.

PubMed ID: 15039446

DOI: 10.1074/jbc.m312458200

PubMed ID: 15265897

Title: Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist.

PubMed ID: 15265897

DOI: 10.4049/jimmunol.173.3.1681

PubMed ID: 15123770

Title: Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain.

PubMed ID: 15123770

DOI: 10.1189/jlb.0605298

PubMed ID: 16377614

Title: The structure of the interleukin-15 alpha receptor and its implications for ligand binding.

PubMed ID: 16377614

DOI: 10.1074/jbc.m513118200

PubMed ID: 17643103

Title: Crystal structure of the IL-15-IL-15Ralpha complex, a cytokine-receptor unit presented in trans.

PubMed ID: 17643103

DOI: 10.1038/ni1492

Sequence Information:

  • Length: 267
  • Mass: 28233
  • Checksum: A9CFC885189E96BE
  • Sequence:
    • MAPRRARGCR TLGLPALLLL LLLRPPATRG ITCPPPMSVE HADIWVKSYS LYSRERYICN 
SGFKRKAGTS SLTECVLNKA TNVAHWTTPS LKCIRDPALV HQRPAPPSTV TTAGVTPQPE 
SLSPSGKEPA ASSPSSNNTA ATTAAIVPGS QLMPSKSPST GTTEISSHES SHGTPSQTTA 
KNWELTASAS HQPPGVYPQG HSDTTVAIST STVLLCGLSA VSLLACYLKS RQTPPLASVE 
MEAMEALPVT WGTSSRDEDL ENCSHHL

Genular Protein ID: 57499220

Symbol: G8CVM3_HUMAN

Name: N/A

UniProtKB Accession Codes:

G8CVM3

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 23074221

Title: Paracrine and Transpresentation Functions of IL-15 Are Mediated by Diverse Splice Versions of IL-15R? in Human Monocytes and Dendritic Cells.

PubMed ID: 23074221

DOI: 10.1074/jbc.M112.378612

Sequence Information:

  • Length: 318
  • Mass: 34155
  • Checksum: EF85CD8BA38DF083
  • Sequence:
    • MAPRRARGCR TLGLPALLLL LLLRPPATRD ARDRLAVLAG RSRISESFNH EVQTHEACVR 
LRTMENCPQC HHHRTSRQQA GITCPPPMSV EHADIWVKSY SLYSRERYIC NSGFKRKAGT 
SSLTECVLNK ATNVAHWTTP SLKCIRDPAL VHQRPAPPST VTTAGVTPQP ESLSPSGKEP 
AASSPSSNNT AATTAAIVPG SQLMPSKSPS TGTTEISSHE SSHGTPSQTT AKNWELTASA 
SHQPPGVYPQ GHSDTTVAIS TSTVLLCGLS AVSLLACYLK SRQTPPLASV EMEAMEALPV 
TWGTSSRDED LENCSHHL

Genular Protein ID: 3171314224

Symbol: A0A0A0MS77_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MS77

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 1 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PaxDb 1 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 353
  • Mass: 37563
  • Checksum: 27D8761E7B8783EF
  • Sequence:
    • MRLAGRQVPE QRSPPPPGLG SARPGSPAVS CGAAAMAPRR ARGCRTLGLP ALLLLLLLRP 
PATRDARDRL AVLAGRSRIS ESFNHEVQTH EACVRLRTME NCPQCHHHRT SRQQAGITCP 
PPMSVEHADI WVKSYSLYSR ERYICNSGFK RKAGTSSLTE CVLNKATNVA HWTTPSLKCI 
RDPALVHQRP APPSTVTTAG VTPQPESLSP SGKEPAASSP SSNNTAATTA AIVPGSQLMP 
SKSPSTGTTE ISSHESSHGT PSQTTAKNWE LTASASHQPP GVYPQGHSDT TVAISTSTVL 
LCGLSAVSLL ACYLKSRQTP PLASVEMEAM EALPVTWGTS SRDEDLENCS HHL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.