Details for: IMPA1

Gene ID: 3612

Symbol: IMPA1

Ensembl ID: ENSG00000133731

Description: inositol monophosphatase 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 153.5245
    Cell Significance Index: -23.8800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 87.2879
    Cell Significance Index: -22.1400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 54.9010
    Cell Significance Index: -25.9200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 52.2822
    Cell Significance Index: -21.2400
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 38.5680
    Cell Significance Index: -25.8800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 22.3411
    Cell Significance Index: -21.3300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.8628
    Cell Significance Index: -24.4900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.9810
    Cell Significance Index: -21.3800
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.2804
    Cell Significance Index: -19.2900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.2658
    Cell Significance Index: -24.7300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.8335
    Cell Significance Index: -8.3900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.8346
    Cell Significance Index: 27.4900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.3486
    Cell Significance Index: 18.4000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1569
    Cell Significance Index: 52.4400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.8170
    Cell Significance Index: 162.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.7701
    Cell Significance Index: 53.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7517
    Cell Significance Index: 150.7900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7408
    Cell Significance Index: 73.2800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7398
    Cell Significance Index: 668.0300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.6711
    Cell Significance Index: 14.5400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.6034
    Cell Significance Index: 9.6800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5628
    Cell Significance Index: 16.2200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.5324
    Cell Significance Index: 95.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4867
    Cell Significance Index: 59.8500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4187
    Cell Significance Index: 26.3900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4123
    Cell Significance Index: 21.4200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2526
    Cell Significance Index: 48.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2370
    Cell Significance Index: 129.4400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.2337
    Cell Significance Index: 6.3600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2276
    Cell Significance Index: 31.2600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.2036
    Cell Significance Index: 3.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1939
    Cell Significance Index: 14.8800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1861
    Cell Significance Index: 21.9400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1825
    Cell Significance Index: 65.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1707
    Cell Significance Index: 118.0800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.1591
    Cell Significance Index: 20.4000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1167
    Cell Significance Index: 4.1000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0968
    Cell Significance Index: 42.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0809
    Cell Significance Index: 3.7700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0702
    Cell Significance Index: 31.8800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0592
    Cell Significance Index: 1.2600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0380
    Cell Significance Index: 1.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0265
    Cell Significance Index: 4.5300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0235
    Cell Significance Index: 0.6300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0219
    Cell Significance Index: 41.1900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0215
    Cell Significance Index: 13.6600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0084
    Cell Significance Index: 0.5400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0030
    Cell Significance Index: 0.4300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0023
    Cell Significance Index: -1.7200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0040
    Cell Significance Index: -5.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0050
    Cell Significance Index: -9.1900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0054
    Cell Significance Index: -3.9600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0069
    Cell Significance Index: -10.6300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.0107
    Cell Significance Index: -1.7400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0158
    Cell Significance Index: -9.8800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0195
    Cell Significance Index: -11.0000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0207
    Cell Significance Index: -1.1600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0208
    Cell Significance Index: -15.7300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0432
    Cell Significance Index: -1.2700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0446
    Cell Significance Index: -5.0900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0595
    Cell Significance Index: -6.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0615
    Cell Significance Index: -12.9600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0684
    Cell Significance Index: -3.5900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0726
    Cell Significance Index: -20.8800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0828
    Cell Significance Index: -9.6500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1058
    Cell Significance Index: -7.4800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1068
    Cell Significance Index: -12.2300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1084
    Cell Significance Index: -3.0300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1108
    Cell Significance Index: -5.6000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1157
    Cell Significance Index: -14.9500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1330
    Cell Significance Index: -6.2500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1347
    Cell Significance Index: -9.0600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1479
    Cell Significance Index: -6.5400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1661
    Cell Significance Index: -10.2100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1701
    Cell Significance Index: -12.6800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1766
    Cell Significance Index: -9.2000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2004
    Cell Significance Index: -5.2700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2062
    Cell Significance Index: -21.4700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2193
    Cell Significance Index: -8.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2221
    Cell Significance Index: -17.5900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2276
    Cell Significance Index: -5.8200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2331
    Cell Significance Index: -8.1000
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2433
    Cell Significance Index: -2.9000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2453
    Cell Significance Index: -3.6200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2584
    Cell Significance Index: -6.9000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2591
    Cell Significance Index: -6.9300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.2612
    Cell Significance Index: -2.1300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2755
    Cell Significance Index: -4.6100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2843
    Cell Significance Index: -4.2000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3483
    Cell Significance Index: -9.9400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3592
    Cell Significance Index: -7.0100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3925
    Cell Significance Index: -12.5000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3969
    Cell Significance Index: -8.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4080
    Cell Significance Index: -10.2000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4193
    Cell Significance Index: -25.7100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4386
    Cell Significance Index: -2.6500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.4444
    Cell Significance Index: -4.6000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4534
    Cell Significance Index: -14.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4766
    Cell Significance Index: -12.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4877
    Cell Significance Index: -15.6200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Enzymatic activity:** IMPA1 is a phosphatase enzyme that catalyzes the hydrolysis of inositol monophosphates to inositol and phosphate. 2. **Subcellular localization:** IMPA1 is primarily found in the cytosol, where it regulates inositol phosphate metabolism. 3. **Cellular expression:** IMPA1 is highly expressed in neurons, particularly in corticothalamic-projecting glutamatergic cortical neurons, L6b glutamatergic cortical neurons, and dopaminergic neurons. 4. **Protein-protein interactions:** IMPA1 interacts with various proteins, including other enzymes and signaling molecules, to regulate inositol phosphate metabolism. **Pathways and Functions:** 1. **Inositol biosynthetic process:** IMPA1 is involved in the regulation of inositol biosynthesis, which is essential for neuronal signaling and cell growth. 2. **Inositol metabolic process:** IMPA1 plays a crucial role in the breakdown of inositol phosphates, which are involved in various cellular processes, including cell signaling, growth, and differentiation. 3. **Signal transduction:** IMPA1 is involved in the regulation of signal transduction pathways, including the phosphoinositide 3-kinase (PI3K) pathway and the mitogen-activated protein kinase (MAPK) pathway. 4. **Neurotransmitter regulation:** IMPA1 regulates the levels of neurotransmitters, such as glutamate and dopamine, which are essential for neuronal communication. **Clinical Significance:** 1. **Neurological disorders:** IMPA1 has been implicated in various neurological disorders, including schizophrenia, bipolar disorder, and autism spectrum disorder. 2. **Lithium therapy:** IMPA1 has been shown to interact with lithium, a commonly used medication for treating bipolar disorder, and may contribute to the therapeutic effects of lithium. 3. **Cancer research:** IMPA1 has been found to be overexpressed in certain types of cancer, including colon cancer, and may play a role in cancer progression. 4. **Neurodegenerative diseases:** IMPA1 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, and may contribute to disease progression. In conclusion, IMPA1 is a critical enzyme involved in inositol metabolism and neuronal signaling. Its dysregulation has been implicated in various neurological disorders and may contribute to disease progression. Further research is needed to fully understand the role of IMPA1 in human health and disease.

Genular Protein ID: 682577318

Symbol: IMPA1_HUMAN

Name: Inositol monophosphatase 1

UniProtKB Accession Codes:

P29218 B2R733 B4DLN3 B7Z6Q4 J3KQT7 Q9UK71

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 15 ChEMBL 1 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 DrugCentral 1 EC 2 EMBL 18 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 13 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 REPRODUCTION-2DPAGE 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 2 SABIO-RK 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1377913

Title: cDNA cloning of human and rat brain myo-inositol monophosphatase. Expression and characterization of the human recombinant enzyme.

PubMed ID: 1377913

DOI: 10.1042/bj2840749

PubMed ID: 9339367

Title: Genomic structure and chromosomal localization of a human myo-inositol monophosphatase gene (IMPA).

PubMed ID: 9339367

DOI: 10.1006/geno.1997.4862

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9462881

Title: Brain inositol monophosphatase identified as a galactose 1-phosphatase.

PubMed ID: 9462881

DOI: 10.1016/s0006-8993(97)01042-1

PubMed ID: 17068342

Title: Spatial expression patterns and biochemical properties distinguish a second myo-inositol monophosphatase IMPA2 from IMPA1.

PubMed ID: 17068342

DOI: 10.1074/jbc.m604474200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26416544

Title: A homozygous loss-of-function mutation in inositol monophosphatase 1 (IMPA1) causes severe intellectual disability.

PubMed ID: 26416544

DOI: 10.1038/mp.2015.150

PubMed ID: 1332026

Title: Structure of inositol monophosphatase, the putative target of lithium therapy.

PubMed ID: 1332026

DOI: 10.1073/pnas.89.21.10031

PubMed ID: 8068620

Title: Structural analysis of inositol monophosphatase complexes with substrates.

PubMed ID: 8068620

DOI: 10.1021/bi00198a011

PubMed ID: 8068621

Title: Structural studies of metal binding by inositol monophosphatase: evidence for two-metal ion catalysis.

PubMed ID: 8068621

DOI: 10.1021/bi00198a012

PubMed ID: 8718889

Title: The contribution of lysine-36 to catalysis by human myo-inositol monophosphatase.

PubMed ID: 8718889

DOI: 10.1021/bi9603837

PubMed ID: 23027737

Title: Cloning, expression, purification, crystallization and X-ray analysis of inositol monophosphatase from Mus musculus and Homo sapiens.

PubMed ID: 23027737

DOI: 10.1107/s1744309112035191

Sequence Information:

  • Length: 277
  • Mass: 30189
  • Checksum: 861D5617E1C04627
  • Sequence:
    • MADPWQECMD YAVTLARQAG EVVCEAIKNE MNVMLKSSPV DLVTATDQKV EKMLISSIKE 
KYPSHSFIGE ESVAAGEKSI LTDNPTWIID PIDGTTNFVH RFPFVAVSIG FAVNKKIEFG 
VVYSCVEGKM YTARKGKGAF CNGQKLQVSQ QEDITKSLLV TELGSSRTPE TVRMVLSNME 
KLFCIPVHGI RSVGTAAVNM CLVATGGADA YYEMGIHCWD VAGAGIIVTE AGGVLMDVTG 
GPFDLMSRRV IAANNRILAE RIAKEIQVIP LQRDDED

Genular Protein ID: 2797699337

Symbol: A0A140VJL8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A140VJL8

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 14 DNASU 1 DisGeNET 1 EC 2 EMBL 2 ExpressionAtlas 1 GO 8 Gene3D 2 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 2 PROSITE 2 Pfam 1 PhylomeDB 1 RefSeq 1 Rhea 2 RuleBase 1 SMR 1 SUPFAM 1 UniPathway 1 VEuPathDB 1

Sequence Information:

  • Length: 336
  • Mass: 36695
  • Checksum: 5838EB952D0C2FA6
  • Sequence:
    • MGQRPGPVLP AVAVLGQVAK RKVAWLLRWK AVTRTETAGN SSGVYGFGKM KIFVKYFQKM 
ADPWQECMDY AVTLARQAGE VVCEAIKNEM NVMLKSSPVD LVTATDQKVE KMLISSIKEK 
YPSHSFIGEE SVAAGEKSIL TDNPTWIIDP IDGTTNFVHR FPFVAVSIGF AVNKKIEFGV 
VYSCVEGKMY TARKGKGAFC NGQKLQVSQQ EDITKSLLVT ELGSSRTPET VRMVLSNMEK 
LFCIPVHGIR SVGTAAVNMC LVATGGADAY YEMGIHCWDV AGAGIIVTEA GGVLMDVTGG 
PFDLMSRRVI AANNRILAER IAKEIQVIPL QRDDED

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.