Details for: ITGAX

Gene ID: 3687

Symbol: ITGAX

Ensembl ID: ENSG00000140678

Description: integrin subunit alpha X

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 60.9469
    Cell Significance Index: -9.4800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 37.2767
    Cell Significance Index: -9.4600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 25.5134
    Cell Significance Index: -10.3700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 20.4322
    Cell Significance Index: -10.5100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.7051
    Cell Significance Index: -9.5000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.8719
    Cell Significance Index: 53.0800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 2.6830
    Cell Significance Index: 41.5100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.9009
    Cell Significance Index: 24.1400
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.8901
    Cell Significance Index: 11.0100
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.2641
    Cell Significance Index: 2.8100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1545
    Cell Significance Index: 1.2600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0566
    Cell Significance Index: 35.3400
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: 0.0343
    Cell Significance Index: 0.2900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0067
    Cell Significance Index: 1.3300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0034
    Cell Significance Index: -0.3500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0040
    Cell Significance Index: -7.6000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0047
    Cell Significance Index: -3.4900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0064
    Cell Significance Index: -3.6000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0094
    Cell Significance Index: -17.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0100
    Cell Significance Index: -2.1100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0102
    Cell Significance Index: -7.6900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0102
    Cell Significance Index: -15.7000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0127
    Cell Significance Index: -17.2400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0138
    Cell Significance Index: -8.7700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0139
    Cell Significance Index: -10.2300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0179
    Cell Significance Index: -9.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0215
    Cell Significance Index: -7.7100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0222
    Cell Significance Index: -9.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0228
    Cell Significance Index: -10.3300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0274
    Cell Significance Index: -7.8900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0307
    Cell Significance Index: -5.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0336
    Cell Significance Index: -6.7500
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.0366
    Cell Significance Index: -0.4000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0379
    Cell Significance Index: -6.8400
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.0508
    Cell Significance Index: -0.6100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0566
    Cell Significance Index: -3.6500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0579
    Cell Significance Index: -8.4200
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0613
    Cell Significance Index: -7.0000
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0615
    Cell Significance Index: -0.9000
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.0617
    Cell Significance Index: -0.8200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0648
    Cell Significance Index: -8.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0669
    Cell Significance Index: -8.5700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0683
    Cell Significance Index: -8.0600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0686
    Cell Significance Index: -8.4400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0755
    Cell Significance Index: -2.0200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0757
    Cell Significance Index: -3.8300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0774
    Cell Significance Index: -10.0100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0877
    Cell Significance Index: -3.5900
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0891
    Cell Significance Index: -1.2500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0895
    Cell Significance Index: -10.4300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0898
    Cell Significance Index: -9.3500
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0984
    Cell Significance Index: -0.8600
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0998
    Cell Significance Index: -1.7000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1042
    Cell Significance Index: -4.9000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1102
    Cell Significance Index: -4.7900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1102
    Cell Significance Index: -3.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1119
    Cell Significance Index: -8.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1205
    Cell Significance Index: -13.8100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1331
    Cell Significance Index: -9.9200
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1360
    Cell Significance Index: -2.6600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1476
    Cell Significance Index: -10.4400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1533
    Cell Significance Index: -10.3100
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: -0.1630
    Cell Significance Index: -0.4300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1645
    Cell Significance Index: -10.1100
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.1654
    Cell Significance Index: -1.3400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1775
    Cell Significance Index: -4.3000
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.1783
    Cell Significance Index: -1.8200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1865
    Cell Significance Index: -9.6900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1960
    Cell Significance Index: -10.2100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1969
    Cell Significance Index: -11.0500
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.2071
    Cell Significance Index: -2.4400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2306
    Cell Significance Index: -10.2000
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.2311
    Cell Significance Index: -3.5100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.2329
    Cell Significance Index: -10.5600
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.2411
    Cell Significance Index: -3.3800
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.2497
    Cell Significance Index: -2.2000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2513
    Cell Significance Index: -7.3800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2565
    Cell Significance Index: -8.9900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2576
    Cell Significance Index: -3.7400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2594
    Cell Significance Index: -16.3500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2654
    Cell Significance Index: -10.0500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2801
    Cell Significance Index: -9.1700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2840
    Cell Significance Index: -13.2400
  • Cell Name: classical monocyte (CL0000860)
    Fold Change: -0.2857
    Cell Significance Index: -2.6600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2933
    Cell Significance Index: -9.3400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2945
    Cell Significance Index: -10.8100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.3259
    Cell Significance Index: -11.4500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3299
    Cell Significance Index: -8.4800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.3395
    Cell Significance Index: -4.8700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.3464
    Cell Significance Index: -9.9300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.3513
    Cell Significance Index: -9.3800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3555
    Cell Significance Index: -10.4700
  • Cell Name: CD16-positive, CD56-dim natural killer cell, human (CL0000939)
    Fold Change: -0.3572
    Cell Significance Index: -3.1800
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3616
    Cell Significance Index: -3.3300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3634
    Cell Significance Index: -10.3700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.3677
    Cell Significance Index: -9.1700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3680
    Cell Significance Index: -7.8100
  • Cell Name: monocyte-derived dendritic cell (CL0011031)
    Fold Change: -0.3749
    Cell Significance Index: -6.4400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3784
    Cell Significance Index: -9.4400
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.3807
    Cell Significance Index: -9.7000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Expression Pattern**: ITGAX is highly expressed in immune cells, including decidual natural killer cells, CD56-positive and CD161-positive immature natural killer cells, and CD14-positive and CD16-positive monocytes. 2. **Cellular Localization**: The ITGAX protein is primarily associated with the plasma membrane, where it interacts with its beta2 subunit to form the integrin alphax-beta2 complex. 3. **Function**: The integrin alphax-beta2 complex mediates cell-cell and cell-matrix adhesion, and plays a critical role in signaling pathways that regulate immune responses, angiogenesis, and tissue morphogenesis. **Pathways and Functions** 1. **Integrin-Mediated Signaling Pathway**: The integrin alphax-beta2 complex interacts with various ligands, including fibrinogen, vitronectin, and ICAM-1, to trigger signaling cascades that regulate immune responses, cell migration, and tissue morphogenesis. 2. **Angiogenesis**: The ITGAX gene is involved in the regulation of angiogenesis, a process critical for tissue development and wound healing. 3. **Immune System**: The integrin alphax-beta2 complex plays a key role in immune system function, including cell-cell adhesion, cytokine signaling, and neutrophil degranulation. 4. **Cell Migration**: The ITGAX gene is involved in regulating cell migration, a process critical for tissue development, immune responses, and cancer metastasis. 5. **Gene Expression**: The ITGAX protein regulates gene expression through the activation of transcription factors and signaling pathways. **Clinical Significance** 1. **Immunodeficiency Disorders**: Mutations in the ITGAX gene have been associated with immunodeficiency disorders, including leukocyte adhesion deficiency (LAD) type 1. 2. **Cancer Metastasis**: The integrin alphax-beta2 complex plays a role in cancer metastasis, highlighting the potential for ITGAX as a therapeutic target. 3. **Angiogenesis-Related Disorders**: The ITGAX gene is involved in angiogenesis, a process critical in various diseases, including cancer, cardiovascular disease, and diabetic retinopathy. 4. **Neurological Disorders**: The ITGAX protein is expressed in the central nervous system, and alterations in its expression have been associated with neurological disorders, including multiple sclerosis and Alzheimer's disease. In conclusion, the ITGAX gene plays a critical role in regulating immune responses, angiogenesis, and tissue morphogenesis. Its dysregulation has been implicated in various diseases, highlighting the potential for therapeutic targeting of this gene in the treatment of immunodeficiency disorders, cancer metastasis, and angiogenesis-related diseases.

Genular Protein ID: 376676123

Symbol: ITAX_HUMAN

Name: Integrin alpha-X

UniProtKB Accession Codes:

P20702 Q8IVA6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTC 1 CTD 1 ChEBI 15 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 27 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 5 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3327687

Title: cDNA cloning and complete primary structure of the alpha subunit of a leukocyte adhesion glycoprotein, p150,95.

PubMed ID: 3327687

DOI: 10.1002/j.1460-2075.1987.tb02746.x

PubMed ID: 2303426

Title: Genomic structure of an integrin alpha subunit, the leukocyte p150,95 molecule.

PubMed ID: 2303426

DOI: 10.1016/s0021-9258(19)39870-9

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3549901

Title: Purification and alpha subunit N-terminal sequences of human Mac-1 and p150,95 leukocyte adhesion proteins.

PubMed ID: 3549901

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20033057

Title: Structure of an integrin with an alphaI domain, complement receptor type 4.

PubMed ID: 20033057

DOI: 10.1038/emboj.2009.367

PubMed ID: 22844534

Title: Structure and binding interface of the cytosolic tails of alphaXbeta2 integrin.

PubMed ID: 22844534

DOI: 10.1371/journal.pone.0041924

PubMed ID: 21763482

Title: VPS35 mutations in Parkinson disease.

PubMed ID: 21763482

DOI: 10.1016/j.ajhg.2011.06.001

Sequence Information:

  • Length: 1163
  • Mass: 127829
  • Checksum: 8947288C43E76BE2
  • Sequence:
    • MTRTRAALLL FTALATSLGF NLDTEELTAF RVDSAGFGDS VVQYANSWVV VGAPQKITAA 
NQTGGLYQCG YSTGACEPIG LQVPPEAVNM SLGLSLASTT SPSQLLACGP TVHHECGRNM 
YLTGLCFLLG PTQLTQRLPV SRQECPRQEQ DIVFLIDGSG SISSRNFATM MNFVRAVISQ 
FQRPSTQFSL MQFSNKFQTH FTFEEFRRSS NPLSLLASVH QLQGFTYTAT AIQNVVHRLF 
HASYGARRDA AKILIVITDG KKEGDSLDYK DVIPMADAAG IIRYAIGVGL AFQNRNSWKE 
LNDIASKPSQ EHIFKVEDFD ALKDIQNQLK EKIFAIEGTE TTSSSSFELE MAQEGFSAVF 
TPDGPVLGAV GSFTWSGGAF LYPPNMSPTF INMSQENVDM RDSYLGYSTE LALWKGVQSL 
VLGAPRYQHT GKAVIFTQVS RQWRMKAEVT GTQIGSYFGA SLCSVDVDSD GSTDLVLIGA 
PHYYEQTRGG QVSVCPLPRG WRRWWCDAVL YGEQGHPWGR FGAALTVLGD VNGDKLTDVV 
IGAPGEEENR GAVYLFHGVL GPSISPSHSQ RIAGSQLSSR LQYFGQALSG GQDLTQDGLV 
DLAVGARGQV LLLRTRPVLW VGVSMQFIPA EIPRSAFECR EQVVSEQTLV QSNICLYIDK 
RSKNLLGSRD LQSSVTLDLA LDPGRLSPRA TFQETKNRSL SRVRVLGLKA HCENFNLLLP 
SCVEDSVTPI TLRLNFTLVG KPLLAFRNLR PMLAADAQRY FTASLPFEKN CGADHICQDN 
LGISFSFPGL KSLLVGSNLE LNAEVMVWND GEDSYGTTIT FSHPAGLSYR YVAEGQKQGQ 
LRSLHLTCDS APVGSQGTWS TSCRINHLIF RGGAQITFLA TFDVSPKAVL GDRLLLTANV 
SSENNTPRTS KTTFQLELPV KYAVYTVVSS HEQFTKYLNF SESEEKESHV AMHRYQVNNL 
GQRDLPVSIN FWVPVELNQE AVWMDVEVSH PQNPSLRCSS EKIAPPASDF LAHIQKNPVL 
DCSIAGCLRF RCDVPSFSVQ EELDFTLKGN LSFGWVRQIL QKKVSVVSVA EITFDTSVYS 
QLPGQEAFMR AQTTTVLEKY KVHNPTPLIV GSSIGGLLLL ALITAVLYKV GFFKRQYKEM 
MEEANGQIAP ENGTQTPSPP SEK

Genular Protein ID: 2292553503

Symbol: H3BN02_HUMAN

Name: N/A

UniProtKB Accession Codes:

H3BN02

Database IDs:

ARBA 15 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 5 GeneTree 1 HGNC 1 InterPro 11 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 6 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

Sequence Information:

  • Length: 1169
  • Mass: 128537
  • Checksum: 0E4C64E082AADB8B
  • Sequence:
    • MTRTRAALLL FTALATSLGF NLDTEELTAF RVDSAGFGDS VVQYANSWVV VGAPQKITAA 
NQTGGLYQCG YSTGACEPIG LQVPPEAVNM SLGLSLASTT SPSQLLACGP TVHHECGRNM 
YLTGLCFLLG PTQLTQRLPV SRQECPRQEQ DIVFLIDGSG SISSRNFATM MNFVRAVISQ 
FQRPSTQFSL MQFSNKFQTH FTFEEFRRSS NPLSLLASVH QLQGFTYTAT AIQNVVHRLF 
HASYGARRDA AKILIVITDG KKEGDSLDYK DVIPMADAAG IIRYAIGVGL AFQNRNSWKE 
LNDIASKPSQ EHIFKVEDFD ALKDIQNQLK EKIFAIEGTE TTSSSSFELE MAQEGFSAVF 
TPDGPVLGAV GSFTWSGGAF LYPPNMSPTF INMSQENVDM RDSYLGYSTE LALWKGVQSL 
VLGAPRYQHT GKAVIFTQVS RQWRMKAEVT GTQIGSYFGA SLCSVDVDSD GSTDLVLIGA 
PHYYEQTRGG QVSVCPLPRG WRRWWCDAVL YGEQGHPWGR FGAALTVLGD VNGDKLTDVV 
IGAPGEEENR GAVYLFHGVL GPSISPSHSQ RIAGSQLSSR LQYFGQALSG GQDLTQDGLV 
DLAVGARGQV LLLRTRPVLW VGVSMQFIPA EIPRSAFECR EQVVSEQTLV QSNICLYIDK 
RSKNLLGSRD LQSSVTLDLA LDPGRLSPRA TFQETKNRSL SRVRVLGLKA HCENFNLLLP 
SCVEDSVTPI TLRLNFTLVG KPLLAFRNLR PMLAADAQRY FTASLPFEKN CGADHICQDN 
LGISFSFPGL KSLLVGSNLE LNAEVMVWND GEDSYGTTIT FSHPAGLSYR YVAEGQKQGQ 
LRSLHLTCDS APVGSQGTWS TSCRINHLIF RGGAQITFLA TFDVSPKAVL GDRLLLTANV 
SSENNTPRTS KTTFQLELPV KYAVYTVVSS HEQFTKYLNF SESEEKESHV AMHRYQVNNL 
GQRDLPVSIN FWVPVELNQE AVWMDVEVSH PQNPSLRCSS EKIAPPASDF LAHIQKNPVL 
DCSIAGCLRF RCDVPSFSVQ EELDFTLKGN LSFGWVRQIL QKKVSVVSVA EITFDTSVYS 
QLPGQEAFMR AQTTTVLEKY KVHNPTPLIV GSSIGGLLLL ALITAVLYKV GFFKRQYKEM 
MEEANGQIAP ENGTQTPSPP TPHYPQDNV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.