Details for: FLG2

Gene ID: 388698

Symbol: FLG2

Ensembl ID: ENSG00000143520

Description: filaggrin 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 3.3862
    Cell Significance Index: 7.6300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.3505
    Cell Significance Index: -0.7700
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.3265
    Cell Significance Index: 5.1800
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.2167
    Cell Significance Index: 2.8000
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.1748
    Cell Significance Index: 1.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0858
    Cell Significance Index: 1.1700
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.0751
    Cell Significance Index: 0.8500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0685
    Cell Significance Index: 4.3200
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.0677
    Cell Significance Index: 0.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0442
    Cell Significance Index: 3.3900
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 0.0374
    Cell Significance Index: 0.4700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0154
    Cell Significance Index: 3.0800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: 0.0099
    Cell Significance Index: 0.1400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.0087
    Cell Significance Index: 0.1700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0062
    Cell Significance Index: 0.3100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0041
    Cell Significance Index: 6.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0028
    Cell Significance Index: 1.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0017
    Cell Significance Index: 3.1600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.0012
    Cell Significance Index: 0.0300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0011
    Cell Significance Index: 0.3100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0008
    Cell Significance Index: 1.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0005
    Cell Significance Index: -0.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0019
    Cell Significance Index: -2.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0020
    Cell Significance Index: -1.3000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0023
    Cell Significance Index: -1.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0034
    Cell Significance Index: -2.5300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0036
    Cell Significance Index: -1.9600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0044
    Cell Significance Index: -2.4900
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0044
    Cell Significance Index: -0.1100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0053
    Cell Significance Index: -2.4000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0054
    Cell Significance Index: -0.3300
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0059
    Cell Significance Index: -0.1000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0071
    Cell Significance Index: -0.3300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0077
    Cell Significance Index: -1.5200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0079
    Cell Significance Index: -1.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0081
    Cell Significance Index: -0.4200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0082
    Cell Significance Index: -1.4700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0088
    Cell Significance Index: -0.4000
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.0097
    Cell Significance Index: -0.0600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0107
    Cell Significance Index: -2.2600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0122
    Cell Significance Index: -2.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0126
    Cell Significance Index: -1.7300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0133
    Cell Significance Index: -1.6300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0160
    Cell Significance Index: -0.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0163
    Cell Significance Index: -1.6600
  • Cell Name: CD8-positive, alpha-beta memory T cell, CD45RO-positive (CL0001203)
    Fold Change: -0.0183
    Cell Significance Index: -0.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0209
    Cell Significance Index: -2.4000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0218
    Cell Significance Index: -0.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0223
    Cell Significance Index: -2.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0241
    Cell Significance Index: -1.3500
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.0241
    Cell Significance Index: -0.1900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0263
    Cell Significance Index: -0.9200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0269
    Cell Significance Index: -1.8100
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0272
    Cell Significance Index: -0.6600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0292
    Cell Significance Index: -1.2900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0303
    Cell Significance Index: -0.7800
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0318
    Cell Significance Index: -0.5100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0327
    Cell Significance Index: -0.9100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0330
    Cell Significance Index: -0.6900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0367
    Cell Significance Index: -1.3900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0400
    Cell Significance Index: -0.5900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0412
    Cell Significance Index: -0.8800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0434
    Cell Significance Index: -1.4200
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0444
    Cell Significance Index: -0.5300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0452
    Cell Significance Index: -1.2100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0458
    Cell Significance Index: -1.4600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0459
    Cell Significance Index: -2.4100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0475
    Cell Significance Index: -1.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0494
    Cell Significance Index: -2.3200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0498
    Cell Significance Index: -1.7300
  • Cell Name: tendon cell (CL0000388)
    Fold Change: -0.0500
    Cell Significance Index: -0.6800
  • Cell Name: neuroplacodal cell (CL0000032)
    Fold Change: -0.0528
    Cell Significance Index: -0.6500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0530
    Cell Significance Index: -1.2700
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.0534
    Cell Significance Index: -0.7600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0545
    Cell Significance Index: -0.6800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0569
    Cell Significance Index: -1.4500
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.0570
    Cell Significance Index: -0.7300
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0576
    Cell Significance Index: -0.7500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.0598
    Cell Significance Index: -0.6500
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0600
    Cell Significance Index: -1.2200
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0601
    Cell Significance Index: -0.8100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0608
    Cell Significance Index: -1.7900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0613
    Cell Significance Index: -1.3000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0637
    Cell Significance Index: -2.3400
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: -0.0643
    Cell Significance Index: -0.6800
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0644
    Cell Significance Index: -1.1100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0648
    Cell Significance Index: -1.3000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0649
    Cell Significance Index: -0.9300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0653
    Cell Significance Index: -1.4100
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0657
    Cell Significance Index: -0.7600
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0659
    Cell Significance Index: -0.9600
  • Cell Name: myoblast (CL0000056)
    Fold Change: -0.0672
    Cell Significance Index: -0.6600
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0678
    Cell Significance Index: -0.8700
  • Cell Name: type G enteroendocrine cell (CL0000508)
    Fold Change: -0.0680
    Cell Significance Index: -0.7200
  • Cell Name: pulmonary artery endothelial cell (CL1001568)
    Fold Change: -0.0683
    Cell Significance Index: -0.7300
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0696
    Cell Significance Index: -1.1900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0700
    Cell Significance Index: -1.3900
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: -0.0706
    Cell Significance Index: -0.7900
  • Cell Name: osteoblast (CL0000062)
    Fold Change: -0.0711
    Cell Significance Index: -0.6900
  • Cell Name: CD141-positive myeloid dendritic cell (CL0002394)
    Fold Change: -0.0712
    Cell Significance Index: -0.7700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure and Function:** Filaggrin 2 is a member of the filaggrin family, characterized by its ability to bind calcium ions and participate in the formation of the cornified envelope, a critical component of the skin barrier. 2. **Cellular Expression:** FLG2 is expressed in various cell types, including erythrocytes, goblet cells, and intestinal crypt stem cells, highlighting its broad role in maintaining skin and mucosal homeostasis. 3. **Protein Interactions:** Filaggrin 2 interacts with other proteins, such as filaggrin 1, to form a complex that regulates the structure and function of the skin barrier. **Pathways and Functions:** 1. **Skin Barrier Formation:** Filaggrin 2 plays a crucial role in the formation of the cornified envelope, a hydrophobic lipid layer that prevents water loss and protects against environmental stressors. 2. **Immune Regulation:** FLG2 is involved in the regulation of immune responses, particularly in the innate immune system, where it interacts with neutrophils and other immune cells to modulate inflammation. 3. **Epidermal Morphogenesis:** Filaggrin 2 contributes to the development and maintenance of the epidermis, a critical process in skin homeostasis. 4. **Neutrophil Degranulation:** FLG2 interacts with neutrophils to regulate degranulation, a process involved in the clearance of pathogens and the resolution of inflammation. **Clinical Significance:** 1. **Atopic Dermatitis:** Mutations in the FLG gene, which encodes filaggrin 1, have been associated with atopic dermatitis, a chronic skin disorder characterized by dry, itchy skin. 2. **Psoriasis:** FLG2 has been implicated in the development of psoriasis, a skin disorder characterized by thick, scaly skin. 3. **Skin Barrier Disruption:** FLG2 dysregulation can lead to skin barrier disruption, resulting in increased susceptibility to infections and other skin disorders. 4. **Therapeutic Targets:** FLG2 has emerged as a potential therapeutic target for the treatment of skin disorders, particularly those associated with skin barrier dysfunction. In conclusion, FLG2 is a critical component of the skin barrier, regulating immune responses, epidermal morphogenesis, and skin homeostasis. Its dysregulation has been implicated in various skin disorders, underscoring its importance as a therapeutic target. Further research is needed to fully elucidate the functions of FLG2 and its role in maintaining skin health.

Genular Protein ID: 349781976

Symbol: FILA2_HUMAN

Name: Filaggrin-2

UniProtKB Accession Codes:

Q5D862 Q9H4U1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 5 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 19384417

Title: Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family.

PubMed ID: 19384417

DOI: 10.1371/journal.pone.0005227

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21531719

Title: Deimination of human filaggrin-2 promotes its proteolysis by calpain 1.

PubMed ID: 21531719

DOI: 10.1074/jbc.m110.197400

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28884927

Title: Peeling skin syndrome associated with novel variant in FLG2 gene.

PubMed ID: 28884927

DOI: 10.1002/ajmg.a.38468

PubMed ID: 29758285

Title: Filaggrin 2 Deficiency Results in Abnormal Cell-Cell Adhesion in the Cornified Cell Layers and Causes Peeling Skin Syndrome Type A.

PubMed ID: 29758285

DOI: 10.1016/j.jid.2018.04.032

PubMed ID: 29505760

Title: Generalized Ichthyotic Peeling Skin Syndrome due to FLG2 Mutations.

PubMed ID: 29505760

DOI: 10.1016/j.jid.2018.01.038

PubMed ID: 32341456

Title: De novo variants in CUL3 are associated with global developmental delays with or without infantile spasms.

PubMed ID: 32341456

DOI: 10.1038/s10038-020-0758-2

Sequence Information:

  • Length: 2391
  • Mass: 248073
  • Checksum: 8BC74DE89E0DDC05
  • Sequence:
    • MTDLLRSVVT VIDVFYKYTK QDGECGTLSK GELKELLEKE LHPVLKNPDD PDTVDVIMHM 
LDRDHDRRLD FTEFLLMIFK LTMACNKVLS KEYCKASGSK KHRRGHRHQE EESETEEDEE 
DTPGHKSGYR HSSWSEGEEH GYSSGHSRGT VKCRHGSNSR RLGRQGNLSS SGNQEGSQKR 
YHRSSCGHSW SGGKDRHGSS SVELRERINK SHISPSRESG EEYESGSGSN SWERKGHGGL 
SCGLETSGHE SNSTQSRIRE QKLGSSCSGS GDSGRRSHAC GYSNSSGCGR PQNASSSCQS 
HRFGGQGNQF SYIQSGCQSG IKGGQGHGCV SGGQPSGCGQ PESNPCSQSY SQRGYGAREN 
GQPQNCGGQW RTGSSQSSCC GQYGSGGSQS CSNGQHEYGS CGRFSNSSSS NEFSKCDQYG 
SGSSQSTSFE QHGTGLSQSS GFEQHVCGSG QTCGQHESTS SQSLGYDQHG SSSGKTSGFG 
QHGSGSGQSS GFGQCGSGSG QSSGFGQHGS VSGQSSGFGQ HGSVSGQSSG FGQHESRSRQ 
SSYGQHGSGS SQSSGYGQYG SRETSGFGQH GLGSGQSTGF GQYGSGSGQS SGFGQHGSGS 
GQSSGFGQHE SRSGQSSYGQ HSSGSSQSSG YGQHGSRQTS GFGQHGSGSS QSTGFGQYGS 
GSGQSSGFGQ HVSGSGQSSG FGQHESRSGH SSYGQHGFGS SQSSGYGQHG SSSGQTSGFG 
QHELSSGQSS SFGQHGSGSG QSSGFGQHGS GSGQSSGFGQ HESRSGQSSY GQHSSGSSQS 
SGYGQHGSRQ TSGFGQHGSG SSQSTGFGQY GSGSGQSAGF GQHGSGSGQS SGFGQHESRS 
HQSSYGQHGS GSSQSSGYGQ HGSSSGQTSG FGQHRSSSGQ YSGFGQHGSG SGQSSGFGQH 
GTGSGQYSGF GQHESRSHQS SYGQHGSGSS QSSGYGQHGS SSGQTFGFGQ HRSGSGQSSG 
FGQHGSGSGQ SSGFGQHESG SGKSSGFGQH ESRSSQSNYG QHGSGSSQSS GYGQHGSSSG 
QTTGFGQHRS SSGQYSGFGQ HGSGSDQSSG FGQHGTGSGQ SSGFGQYESR SRQSSYGQHG 
SGSSQSSGYG QHGSNSGQTS GFGQHRPGSG QSSGFGQYGS GSGQSSGFGQ HGSGTGKSSG 
FAQHEYRSGQ SSYGQHGTGS SQSSGCGQHE SGSGPTTSFG QHVSGSDNFS SSGQHISDSG 
QSTGFGQYGS GSGQSTGLGQ GESQQVESGS TVHGRQETTH GQTINTTRHS QSGQGQSTQT 
GSRVTRRRRS SQSENSDSEV HSKVSHRHSE HIHTQAGSHY PKSGSTVRRR QGTTHGQRGD 
TTRHGHSGHG QSTQTGSRTS GRQRFSHSDA TDSEVHSGVS HRPHSQEQTH SQAGSQHGES 
ESTVHERHET TYGQTGEATG HGHSGHGQST QRGSRTTGRR GSGHSESSDS EVHSGGSHRP 
QSQEQTHGQA GSQHGESGST VHGRHGTTHG QTGDTTRHAH YHHGKSTQRG SSTTGRRGSG 
HSESSDSEVH SGGSHTHSGH THGQSGSQHG ESESIIHDRH RITHGQTGDT TRHSYSGHEQ 
TTQTGSRTTG RQRTSHSEST DSEVHSGGSH RPHSREHTYG QAGSQHEEPE FTVHERHGTT 
HGQIGDTTGH SHSGHGQSTQ RGSRTTGRQR SSHSESSDSE VHSGVSHTHT GHTHGQAGSQ 
HGQSESIVPE RHGTTHGQTG DTTRHAHYHH GLTTQTGSRT TGRRGSGHSE YSDSEGYSGV 
SHTHSGHTHG QARSQHGESE SIVHERHGTI HGQTGDTTRH AHSGHGQSTQ TGSRTTGRRS 
SGHSEYSDSE GHSGFSQRPH SRGHTHGQAG SQHGESESIV DERHGTTHGQ TGDTSGHSQS 
GHGQSTQSGS STTGRRRSGH SESSDSEVHS GGSHTHSGHT HSQARSQHGE SESTVHKRHQ 
TTHGQTGDTT EHGHPSHGQT IQTGSRTTGR RGSGHSEYSD SEGPSGVSHT HSGHTHGQAG 
SHYPESGSSV HERHGTTHGQ TADTTRHGHS GHGQSTQRGS RTTGRRASGH SEYSDSEGHS 
GVSHTHSGHA HGQAGSQHGE SGSSVHERHG TTHGQTGDTT RHAHSGHGQS TQRGSRTAGR 
RGSGHSESSD SEVHSGVSHT HSGHTYGQAR SQHGESGSAI HGRQGTIHGQ TGDTTRHGQS 
GHGQSTQTGS RTTGRQRSSH SESSDSEVHS EASPTHSGHT HSQAGSRHGQ SGSSGHGRQG 
TTHGQTGDTT RHAHYGYGQS TQRGSRTTGR RGSGHSESSD SEVHSWGSHT HSGHIQGQAG 
SQQRQPGSTV HGRLETTHGQ TGDTTRHGHS GYGQSTQTGS RSSRASHFQS HSSERQRHGS 
SQVWKHGSYG PAEYDYGHTG YGPSGGSRKS ISNSHLSWST DSTANKQLSR H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.