Details for: RND3
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 32.33rCSI 27.1%PRS 67.05
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CSI 28.36rCSI 36.38%PRS 67.61
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CSI 27.58rCSI 23.78%PRS 68.04
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CSI 23.08rCSI 66.01%PRS 74.73
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CSI 21.83rCSI 18.1%PRS 62.04
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CSI 21.59rCSI 51.23%PRS 66.29
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CSI 20.95rCSI 32%PRS 63.36
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CSI 20.69rCSI 36.49%PRS 70.85
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CSI 18.37rCSI 25.11%PRS 64.37
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CSI 17.92rCSI 20.7%PRS 55.75
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CSI 17.8rCSI 17.14%PRS 62.65
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CSI 14.54rCSI 16.87%PRS 70.29
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CSI 14.19rCSI 34.11%PRS 69.98
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CSI 14.15rCSI 10.97%PRS 64.72
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CSI 12.62rCSI 16.2%PRS 59.84
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CSI 12.3rCSI 9.72%PRS 49.49
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CSI 12.13rCSI 25.17%PRS 59.77
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CSI 10.6rCSI 24.47%PRS 51.65
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CSI 10.36rCSI 10.85%PRS 59.09
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CSI 10.11rCSI 16.28%PRS 52.14
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CSI 9.09rCSI 12.89%PRS 58.93
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CSI 8.68rCSI 12.45%PRS 52.16
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CSI 8.62rCSI 29.14%PRS 66.46
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CSI 8.47rCSI 27.11%PRS 59.71
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CSI 8.38rCSI 23.83%PRS 60.63
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CSI 8.29rCSI 7.71%PRS 63.27
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CSI 7.76rCSI 16.5%PRS 61.83
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CSI 7.47rCSI 8.18%PRS 66.49
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CSI 7.46rCSI 43.42%PRS 71.54
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CSI 7.37rCSI 9.16%PRS 64.36
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CSI 7.33rCSI 11.65%PRS 55
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CSI 7.2rCSI 27.17%PRS 48.83
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CSI 7.11rCSI 10.5%PRS 78.15
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CSI 7.11rCSI 18.47%PRS 78.04
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CSI 7.06rCSI 5.73%PRS 63.13
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CSI 7.02rCSI 29.5%PRS 75.09
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CSI 6.97rCSI 16.35%PRS 67.06
-
CSI 6.94rCSI 18.11%PRS 65.95
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CSI 6.88rCSI 6.35%PRS 64.04
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CSI 6.87rCSI 11.88%PRS 52.73
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CSI 6.82rCSI 12.33%PRS 76.08
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CSI 6.76rCSI 24.02%PRS 71.13
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CSI 6.71rCSI 9.3%PRS 63.63
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CSI 6.71rCSI 10.31%PRS 58.36
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CSI 6.62rCSI 18.62%PRS 59.28
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CSI 6.5rCSI 8.17%PRS 74.54
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CSI 6.48rCSI 6.71%PRS 68.4
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CSI 6.41rCSI 40.02%PRS 54.33
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CSI 6.17rCSI 10.16%PRS 67.89
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CSI 6.01rCSI 7.18%PRS 44.02
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CSI 5.95rCSI 13.61%PRS 62.57
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CSI 5.74rCSI 9.23%PRS 46.29
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CSI 5.69rCSI 5.38%PRS 62.17
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CSI 5.66rCSI 22.6%PRS 78.17
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CSI 5.62rCSI 18.23%PRS 62.86
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CSI 5.53rCSI 20.72%PRS 54.57
-
CSI 5.49rCSI 10.9%PRS 60.29
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CSI 5.48rCSI 8.88%PRS 59.27
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CSI 5.39rCSI 7.49%PRS 61.24
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CSI 5.19rCSI 3.85%PRS 55.13
-
CSI 5.15rCSI 7.01%PRS 54.4
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CSI 5.08rCSI 26.7%PRS 67.84
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CSI 5.04rCSI 10.12%PRS 51.67
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CSI 4.94rCSI 14.59%PRS 65.71
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CSI 4.91rCSI 9.56%PRS 65.67
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CSI 4.83rCSI 20.88%PRS 75.23
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CSI 4.67rCSI 7.45%PRS 55.17
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CSI 4.65rCSI 18.09%PRS 67.19
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CSI 4.46rCSI 6.37%PRS 64.92
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CSI 4.42rCSI 11.63%PRS 80.62
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CSI 4.41rCSI 5.1%PRS 52.85
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CSI 4.36rCSI 4.36%PRS 56.01
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CSI 4.31rCSI 5.76%PRS 62.99
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CSI 4.3rCSI 7.6%PRS 43.35
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CSI 4.28rCSI 3.77%PRS 50.56
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CSI 4.26rCSI 5.43%PRS 69.09
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CSI 4.21rCSI 6.25%PRS 64
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CSI 4.13rCSI 3.67%PRS 60.56
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CSI 4.12rCSI 6.5%PRS 64.99
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CSI 4.09rCSI 10.79%PRS 71.46
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CSI 4.08rCSI 5.07%PRS 42.37
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CSI 4.04rCSI 7.08%PRS 54.48
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CSI 4rCSI 3.86%PRS 53.33
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CSI 4rCSI 18.72%PRS 78.63
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CSI 3.96rCSI 6.12%PRS 60.94
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CSI 3.96rCSI 9.46%PRS 71.04
-
CSI 3.96rCSI 18.97%PRS 62.59
-
CSI 3.96rCSI 4.24%PRS 62.26
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CSI 3.95rCSI 8.12%PRS 52.82
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CSI 3.92rCSI 5.74%PRS 58.67
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CSI 3.88rCSI 4.05%PRS 62.98
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CSI 3.78rCSI 5.17%PRS 55.89
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CSI 3.77rCSI 9.75%PRS 57.56
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CSI 3.73rCSI 8.51%PRS 58.99
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CSI 3.64rCSI 9.73%PRS 53.56
-
CSI 3.64rCSI 6.88%PRS 80.69
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CSI 3.61rCSI 5.76%PRS 66.86
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CSI 3.6rCSI 6.42%PRS 76.11
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CSI 3.59rCSI 5.79%PRS 66.13
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CSI 3.35rCSI 4.14%PRS 59.32
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CSI 0.4rCSI 3.7%PRS 79.3%
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CSI 0.4rCSI 1.3%PRS 51.3%
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CSI 0.4rCSI 2.0%PRS 72.1%
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CSI 0.4rCSI 5.3%PRS 74.2%
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CSI 0.4rCSI 4.1%PRS 79.4%
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CSI 0.5rCSI 3.7%PRS 80.5%
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CSI 0.5rCSI 7.9%PRS 79.1%
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CSI 0.7rCSI 4.0%PRS 76.9%
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CSI 0.7rCSI 2.0%PRS 73.8%
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CSI 0.7rCSI 4.9%PRS 57.9%
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CSI 0.8rCSI 19.7%PRS 79.0%
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CSI 0.8rCSI 14.0%PRS 84.0%
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CSI 0.8rCSI 2.0%PRS 71.5%
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CSI 0.9rCSI 3.4%PRS 75.0%
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CSI 0.9rCSI 5.4%PRS 88.6%
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CSI 0.9rCSI 4.0%PRS 78.9%
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CSI 0.9rCSI 2.5%PRS 69.7%
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CSI 1.0rCSI 6.8%PRS 76.7%
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CSI 1.0rCSI 7.4%PRS 69.3%
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CSI 1.0rCSI 8.1%PRS 55.9%
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CSI 1.0rCSI 7.3%PRS 78.6%
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CSI 1.1rCSI 3.1%PRS 75.1%
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CSI 1.2rCSI 7.6%PRS 81.1%
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CSI 1.2rCSI 1.8%PRS 66.9%
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CSI 1.2rCSI 2.1%PRS 36.8%
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CSI 1.2rCSI 1.8%PRS 75.9%
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CSI 1.2rCSI 8.0%PRS 64.2%
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CSI 1.3rCSI 7.9%PRS 80.8%
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CSI 1.3rCSI 4.2%PRS 62.5%
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CSI 1.3rCSI 3.8%PRS 63.9%
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CSI 1.4rCSI 2.6%PRS 73.0%
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CSI 1.5rCSI 2.9%PRS 78.8%
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CSI 1.5rCSI 7.3%PRS 73.7%
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CSI 1.5rCSI 2.7%PRS 77.6%
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CSI 1.5rCSI 2.8%PRS 77.3%
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CSI 1.5rCSI 2.4%PRS 73.8%
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CSI 1.5rCSI 3.4%PRS 70.6%
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CSI 1.5rCSI 1.6%PRS 72.7%
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CSI 1.6rCSI 3.4%PRS 73.7%
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CSI 1.6rCSI 2.7%PRS 44.3%
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CSI 1.7rCSI 15.3%PRS 72.6%
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CSI 1.7rCSI 18.6%PRS 82.6%
-
CSI 1.7rCSI 10.7%PRS 72.1%
-
CSI 1.7rCSI 5.4%PRS 67.6%
-
CSI 1.7rCSI 2.3%PRS 69.2%
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CSI 1.7rCSI 6.5%PRS 45.0%
-
CSI 1.7rCSI 1.8%PRS 60.6%
-
CSI 1.7rCSI 3.3%PRS 82.2%
-
CSI 1.8rCSI 9.8%PRS 71.9%
-
CSI 1.8rCSI 10.4%PRS 77.2%
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CSI 1.8rCSI 2.3%PRS 45.6%
-
CSI 1.8rCSI 2.2%PRS 60.7%
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CSI 1.9rCSI 4.0%PRS 80.5%
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CSI 2.0rCSI 3.6%PRS 61.7%
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CSI 2.1rCSI 4.5%PRS 76.1%
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CSI 2.1rCSI 5.0%PRS 72.5%
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CSI 2.1rCSI 3.0%PRS 66.0%
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CSI 2.3rCSI 6.6%PRS 75.7%
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CSI 2.3rCSI 7.3%PRS 48.4%
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CSI 2.4rCSI 53.3%PRS 82.8%
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CSI 2.4rCSI 26.5%PRS 74.8%
-
CSI 2.5rCSI 3.3%PRS 71.6%
-
CSI 2.5rCSI 9.5%PRS 53.3%
-
CSI 2.5rCSI 7.2%PRS 52.3%
-
CSI 2.6rCSI 3.8%PRS 67.6%
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CSI 2.6rCSI 5.4%PRS 41.9%
-
CSI 2.7rCSI 4.8%PRS 55.7%
-
CSI 2.7rCSI 6.9%PRS 70.6%
-
CSI 2.7rCSI 6.9%PRS 56.9%
-
CSI 2.9rCSI 10.1%PRS 75.2%
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CSI 3.0rCSI 7.4%PRS 61.1%
-
CSI 3.0rCSI 4.1%PRS 68.8%
-
CSI 3.0rCSI 13.2%PRS 52.8%
-
CSI 3.0rCSI 4.4%PRS 74.3%
-
CSI 3.1rCSI 7.0%PRS 70.4%
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CSI 3.2rCSI 9.1%PRS 74.7%
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CSI 3.2rCSI 4.1%PRS 55.0%
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CSI 3.2rCSI 7.1%PRS 67.0%
-
CSI 3.2rCSI 18.7%PRS 61.1%
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CSI 3.4rCSI 4.1%PRS 59.3%
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CSI 3.6rCSI 5.8%PRS 66.1%
-
CSI 3.6rCSI 6.4%PRS 76.1%
-
CSI 3.6rCSI 5.8%PRS 66.9%
-
CSI 3.6rCSI 6.9%PRS 80.7%
-
CSI 3.6rCSI 9.7%PRS 53.6%
-
CSI 3.7rCSI 8.5%PRS 59.0%
-
CSI 3.8rCSI 9.8%PRS 57.6%
-
CSI 3.8rCSI 5.2%PRS 55.9%
-
CSI 3.9rCSI 4.1%PRS 63.0%
-
CSI 3.9rCSI 5.7%PRS 58.7%
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CSI 4.0rCSI 8.1%PRS 52.8%
-
CSI 4.0rCSI 4.2%PRS 62.3%
-
CSI 4.0rCSI 19.0%PRS 62.6%
-
CSI 4.0rCSI 9.5%PRS 71.0%
-
CSI 4.0rCSI 6.1%PRS 60.9%
-
CSI 4.0rCSI 18.7%PRS 78.6%
-
CSI 4.0rCSI 3.9%PRS 53.3%
-
CSI 4.0rCSI 7.1%PRS 54.5%
-
CSI 4.1rCSI 5.1%PRS 42.4%
-
CSI 4.1rCSI 10.8%PRS 71.5%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 3991818285
Symbol: RND3_HUMAN
Name: Rho-related GTP-binding protein RhoE
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9531558
Title: A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.
PubMed ID: 9531558
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8649376
Title: Identification of a novel human Rho protein with unusual properties: GTPase deficiency and in vivo farnesylation.
PubMed ID: 8649376
PubMed ID: 11940653
Title: Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.
PubMed ID: 11940653
PubMed ID: 12163169
Title: Crystal structure of Rnd3/RhoE: functional implications.
PubMed ID: 12163169
Sequence Information:
- Length: 244
- Mass: 27368
- Checksum: DD2D4021CD42BACC
- Sequence:
MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVNK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS CTVM
Genular Protein ID: 1870712514
Symbol: B2R838_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 244
- Mass: 27341
- Checksum: 241D4021CD5930E4
- Sequence:
MKERRASQKL SSKSIMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL QSENSVRDIF HVATLACVSK TNKNVKRNKS QRATKRISHM PSRPELSAVA TDLRKDKAKS CTVM