Details for: LBP
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 3.5625
Cell Significance Index: 60.0100 - Cell Name: hepatoblast (CL0005026)
Fold Change: 2.7885
Cell Significance Index: 46.9000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 2.3683
Cell Significance Index: -2.9200 - Cell Name: chorionic trophoblast cell (CL0011101)
Fold Change: 2.2486
Cell Significance Index: 6.9800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.4291
Cell Significance Index: 283.6000 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 1.3779
Cell Significance Index: 7.9400 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.9239
Cell Significance Index: 23.0400 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.8963
Cell Significance Index: 21.8700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 0.6766
Cell Significance Index: -2.6700 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: 0.3080
Cell Significance Index: 1.1600 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.2898
Cell Significance Index: 3.6400 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.2861
Cell Significance Index: 29.2300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.1809
Cell Significance Index: 2.6700 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1676
Cell Significance Index: 2.4000 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.1351
Cell Significance Index: 2.0900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1319
Cell Significance Index: 2.2600 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 0.1008
Cell Significance Index: 0.2700 - Cell Name: liver dendritic cell (CL2000055)
Fold Change: 0.0531
Cell Significance Index: 0.1400 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.0168
Cell Significance Index: 0.1600 - Cell Name: cholangiocyte (CL1000488)
Fold Change: 0.0162
Cell Significance Index: 0.1600 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0139
Cell Significance Index: 9.5800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0073
Cell Significance Index: 1.4700 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 0.0069
Cell Significance Index: 0.0300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0052
Cell Significance Index: 0.8900 - Cell Name: slow muscle cell (CL0000189)
Fold Change: 0.0040
Cell Significance Index: 0.0600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0003
Cell Significance Index: 0.5400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0005
Cell Significance Index: -0.9600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0012
Cell Significance Index: -1.8000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0013
Cell Significance Index: -0.7200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0020
Cell Significance Index: -2.6600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0022
Cell Significance Index: -0.8000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0029
Cell Significance Index: -0.8400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0035
Cell Significance Index: -2.6000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0037
Cell Significance Index: -2.3300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0038
Cell Significance Index: -2.9100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0049
Cell Significance Index: -2.7900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0050
Cell Significance Index: -0.7200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0050
Cell Significance Index: -3.1500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0065
Cell Significance Index: -2.9600 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.0079
Cell Significance Index: -0.1100 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0142
Cell Significance Index: -1.0600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0149
Cell Significance Index: -2.6900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0151
Cell Significance Index: -3.1800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0173
Cell Significance Index: -2.0200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0181
Cell Significance Index: -2.3400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0184
Cell Significance Index: -2.5300 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0189
Cell Significance Index: -0.4900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0193
Cell Significance Index: -0.9100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0219
Cell Significance Index: -2.5100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0220
Cell Significance Index: -2.7100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0271
Cell Significance Index: -2.8200 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: -0.0287
Cell Significance Index: -0.1000 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.0321
Cell Significance Index: -0.2700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0340
Cell Significance Index: -0.9500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0376
Cell Significance Index: -2.5300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0394
Cell Significance Index: -3.0200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0409
Cell Significance Index: -3.2400 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0437
Cell Significance Index: -1.1700 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: -0.0450
Cell Significance Index: -0.3600 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0485
Cell Significance Index: -1.4300 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0524
Cell Significance Index: -3.2200 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0535
Cell Significance Index: -1.1200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0564
Cell Significance Index: -1.5400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0567
Cell Significance Index: -2.5100 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.0580
Cell Significance Index: -1.0000 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0597
Cell Significance Index: -1.4900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0598
Cell Significance Index: -1.3100 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.0602
Cell Significance Index: -0.5800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0605
Cell Significance Index: -2.2900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0660
Cell Significance Index: -3.4400 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0666
Cell Significance Index: -1.3000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0674
Cell Significance Index: -3.7800 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0681
Cell Significance Index: -1.0800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0691
Cell Significance Index: -3.1300 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.0698
Cell Significance Index: -0.7200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0737
Cell Significance Index: -3.8300 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0759
Cell Significance Index: -2.6600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0791
Cell Significance Index: -2.5900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0794
Cell Significance Index: -2.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0920
Cell Significance Index: -4.2900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0954
Cell Significance Index: -3.3200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0965
Cell Significance Index: -3.3900 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0985
Cell Significance Index: -4.2800 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -0.0992
Cell Significance Index: -1.3900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0997
Cell Significance Index: -2.6600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0999
Cell Significance Index: -2.8500 - Cell Name: skeletal muscle myoblast (CL0000515)
Fold Change: -0.1021
Cell Significance Index: -1.1100 - Cell Name: Kupffer cell (CL0000091)
Fold Change: -0.1027
Cell Significance Index: -0.9400 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1042
Cell Significance Index: -2.1200 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.1050
Cell Significance Index: -1.5300 - Cell Name: ependymal cell (CL0000065)
Fold Change: -0.1057
Cell Significance Index: -1.2500 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1061
Cell Significance Index: -3.0400 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: -0.1064
Cell Significance Index: -1.2100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1079
Cell Significance Index: -5.4500 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1086
Cell Significance Index: -2.7100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1121
Cell Significance Index: -3.2300 - Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
Fold Change: -0.1124
Cell Significance Index: -1.0400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1131
Cell Significance Index: -2.8900 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: -0.1136
Cell Significance Index: -1.1300 - Cell Name: epicardial adipocyte (CL1000309)
Fold Change: -0.1138
Cell Significance Index: -1.3300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3623877261
Symbol: LBP_HUMAN
Name: Lipopolysaccharide-binding protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2402637
Title: Structure and function of lipopolysaccharide binding protein.
PubMed ID: 2402637
PubMed ID: 7517398
Title: Bactericidal/permeability-increasing protein and lipopolysaccharide (LPS)-binding protein. LPS binding properties and effects on LPS-mediated cell activation.
PubMed ID: 7517398
PubMed ID: 9240454
Title: The genomic organization of the genes for human lipopolysaccharide binding protein (LBP) and bactericidal permeability increasing protein (BPI) is highly conserved.
PubMed ID: 9240454
PubMed ID: 9441745
Title: Similar organization of the lipopolysaccharide-binding protein (LBP) and phospholipid transfer protein (PLTP) genes suggests a common gene family of lipid-binding proteins.
PubMed ID: 9441745
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 11780052
Title: The DNA sequence and comparative analysis of human chromosome 20.
PubMed ID: 11780052
DOI: 10.1038/414865a
PubMed ID: 1698311
Title: CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein.
PubMed ID: 1698311
PubMed ID: 17481951
Title: Structural biology of the LPS recognition.
PubMed ID: 17481951
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 20133493
Title: Lipopolysaccharide-binding protein-mediated Toll-like receptor 4 dimerization enables rapid signal transduction against lipopolysaccharide stimulation on membrane-associated CD14-expressing cells.
PubMed ID: 20133493
PubMed ID: 24120359
Title: The crystal structure of lipopolysaccharide binding protein reveals the location of a frequent mutation that impairs innate immunity.
PubMed ID: 24120359
Sequence Information:
- Length: 481
- Mass: 53384
- Checksum: 5A0E4B9E5E604C72
- Sequence:
MGALARALPS ILLALLLTST PEALGANPGL VARITDKGLQ YAAQEGLLAL QSELLRITLP DFTGDLRIPH VGRGRYEFHS LNIHSCELLH SALRPVPGQG LSLSISDSSI RVQGRWKVRK SFFKLQGSFD VSVKGISISV NLLLGSESSG RPTVTASSCS SDIADVEVDM SGDLGWLLNL FHNQIESKFQ KVLESRICEM IQKSVSSDLQ PYLQTLPVTT EIDSFADIDY SLVEAPRATA QMLEVMFKGE IFHRNHRSPV TLLAAVMSLP EEHNKMVYFA ISDYVFNTAS LVYHEEGYLN FSITDDMIPP DSNIRLTTKS FRPFVPRLAR LYPNMNLELQ GSVPSAPLLN FSPGNLSVDP YMEIDAFVLL PSSSKEPVFR LSVATNVSAT LTFNTSKITG FLKPGKVKVE LKESKVGLFN AELLEALLNY YILNTFYPKF NDKLAEGFPL PLLKRVQLYD LGLQIHKDFL FLGANVQYMR V
Genular Protein ID: 1681281381
Symbol: Q8TCF0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 477
- Mass: 52934
- Checksum: 03D5E9D55A3BA6D0
- Sequence:
MGALARALPS ILLALLLTST PEALGANPGL VARITDKGLQ YAAQEGLLAL QSELLRITLP DFTGDLRIPH VGRGRYEFHS LNIHSCELLH SALRPVPGQG LSLSISDSSI RVQGRWKVRK SFFKLQGSFD VSVKGISISV NLLLGSESSG RPTVTASSCS SDIADVEVDM SGDLGWLLNL FHNQIESKFQ KVLESRICEM IQKSVSSDLQ PYLQTLPVTT EIDSFADIDY SLVEAPRATA QMLEVMFKGE IFHRNHRSPV TLLAAVMSLP EEHNKMVYFA ISDYVFNTAS LVYHEEGYLN FSITDDMIPP DSNIRLTTKS FRPFVPRLAR LYPNMNLELQ GSVPSAPLLN FSPGNLSVDP YMEIDAFVLL PSSSKEPVFR LSVATNVSAT LTFNTSKITG FLKPGKVKVE LKESKVGLFN AELLEALLNY YILNTFYPKF NDKLAEGFPL PLLKRVQLYD LGLQIHKDFP SRRDHPP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.