Details for: ARHGAP6
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 186.1838
Cell Significance Index: -28.9600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 114.4915
Cell Significance Index: -29.0400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 65.8450
Cell Significance Index: -26.7500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 63.7546
Cell Significance Index: -30.1000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 58.6234
Cell Significance Index: -30.1600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 23.4802
Cell Significance Index: -28.9500 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 17.6735
Cell Significance Index: -38.6800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.3517
Cell Significance Index: -29.0100 - Cell Name: preadipocyte (CL0002334)
Fold Change: 6.6193
Cell Significance Index: 129.1900 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 6.3278
Cell Significance Index: 39.0400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 4.0417
Cell Significance Index: 103.8900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 3.2643
Cell Significance Index: 69.7800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 2.8582
Cell Significance Index: 91.5500 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: 2.8013
Cell Significance Index: 18.9800 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 2.5663
Cell Significance Index: 22.7800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: 1.8983
Cell Significance Index: 15.9500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.7384
Cell Significance Index: 623.5200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 1.4185
Cell Significance Index: 71.6900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 1.4033
Cell Significance Index: 94.3600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 1.2141
Cell Significance Index: 126.4200 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.0610
Cell Significance Index: 10.9800 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 1.0474
Cell Significance Index: 16.9000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 1.0322
Cell Significance Index: 468.4700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.6953
Cell Significance Index: 1309.1700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.6830
Cell Significance Index: 472.4200 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.6156
Cell Significance Index: 8.8400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5835
Cell Significance Index: 111.0500 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.5537
Cell Significance Index: 5.7400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.5378
Cell Significance Index: 30.1800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.4559
Cell Significance Index: 12.4100 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.3252
Cell Significance Index: 3.4000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3184
Cell Significance Index: 39.1500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2473
Cell Significance Index: 49.6100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2404
Cell Significance Index: 217.0600 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.2243
Cell Significance Index: 3.0600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2180
Cell Significance Index: 39.2900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1590
Cell Significance Index: 244.7600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1393
Cell Significance Index: 13.7800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0851
Cell Significance Index: 13.8500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0841
Cell Significance Index: 4.3700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0803
Cell Significance Index: 15.9300 - Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 0.0510
Cell Significance Index: 0.4600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0496
Cell Significance Index: 91.5400 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0176
Cell Significance Index: 12.9400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0119
Cell Significance Index: 7.5400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0066
Cell Significance Index: 0.9100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0054
Cell Significance Index: 0.5900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0031
Cell Significance Index: -4.1600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0116
Cell Significance Index: -0.7100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0182
Cell Significance Index: -0.6400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0264
Cell Significance Index: -19.5200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0418
Cell Significance Index: -6.0800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0429
Cell Significance Index: -24.1900 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0434
Cell Significance Index: -1.2500 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0441
Cell Significance Index: -33.3900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0468
Cell Significance Index: -1.1700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0470
Cell Significance Index: -4.8000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0525
Cell Significance Index: -28.6500 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0553
Cell Significance Index: -34.5500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0607
Cell Significance Index: -0.4900 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0812
Cell Significance Index: -23.3600 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0970
Cell Significance Index: -7.4500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1163
Cell Significance Index: -6.0600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1220
Cell Significance Index: -20.8400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1242
Cell Significance Index: -14.4700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.1261
Cell Significance Index: -8.7200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1306
Cell Significance Index: -5.9200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1311
Cell Significance Index: -2.8400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1452
Cell Significance Index: -30.5900 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1513
Cell Significance Index: -19.4000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.1543
Cell Significance Index: -9.2700 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1679
Cell Significance Index: -5.3100 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1740
Cell Significance Index: -3.6100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1907
Cell Significance Index: -11.7200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2387
Cell Significance Index: -30.8400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2507
Cell Significance Index: -3.5900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2741
Cell Significance Index: -32.3300 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2805
Cell Significance Index: -22.2100 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2867
Cell Significance Index: -32.8500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3036
Cell Significance Index: -13.4300 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3373
Cell Significance Index: -5.7800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3520
Cell Significance Index: -7.4700 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3839
Cell Significance Index: -28.6100 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.4119
Cell Significance Index: -6.5400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.4190
Cell Significance Index: -12.0100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4317
Cell Significance Index: -13.7500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.4354
Cell Significance Index: -8.6100 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.4448
Cell Significance Index: -3.4000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4537
Cell Significance Index: -17.1800 - Cell Name: perivascular cell (CL4033054)
Fold Change: -0.4591
Cell Significance Index: -2.1200 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.4623
Cell Significance Index: -11.2800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.4740
Cell Significance Index: -15.5200 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.4822
Cell Significance Index: -31.1100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4897
Cell Significance Index: -25.7100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.5100
Cell Significance Index: -23.9700 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.5208
Cell Significance Index: -7.4900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.5276
Cell Significance Index: -33.2600 - Cell Name: renal principal cell (CL0005009)
Fold Change: -0.5424
Cell Significance Index: -5.7400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.5533
Cell Significance Index: -13.2700 - Cell Name: mural cell (CL0008034)
Fold Change: -0.5561
Cell Significance Index: -6.7700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2971942003
Symbol: RHG06_HUMAN
Name: Rho GTPase-activating protein 6
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10699171
Title: Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA.
PubMed ID: 10699171
DOI: 10.1093/hmg/9.4.477
PubMed ID: 9417914
Title: Cloning and characterization of a novel rho-type GTPase-activating protein gene (ARHGAP6) from the critical region for microphthalmia with linear skin defects.
PubMed ID: 9417914
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 18088087
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
Sequence Information:
- Length: 974
- Mass: 105947
- Checksum: BEE22EB54F019E30
- Sequence:
MSAQSLLHSV FSCSSPASSS AASAKGFSKR KLRQTRSLDP ALIGGCGSDE AGAEGSARGA TAGRLYSPSL PAESLGPRLA SSSRGPPPRA TRLPPPGPLC SSFSTPSTPQ EKSPSGSFHF DYEVPLGRGG LKKSMAWDLP SVLAGPASSR SASSILCSSG GGPNGIFASP RRWLQQRKFQ SPPDSRGHPY VVWKSEGDFT WNSMSGRSVR LRSVPIQSLS ELERARLQEV AFYQLQQDCD LSCQITIPKD GQKRKKSLRK KLDSLGKEKN KDKEFIPQAF GMPLSQVIAN DRAYKLKQDL QRDEQKDASD FVASLLPFGN KRQNKELSSS NSSLSSTSET PNESTSPNTP EPAPRARRRG AMSVDSITDL DDNQSRLLEA LQLSLPAEAQ SKKEKARDKK LSLNPIYRQV PRLVDSCCQH LEKHGLQTVG IFRVGSSKKR VRQLREEFDR GIDVSLEEEH SVHDVAALLK EFLRDMPDPL LTRELYTAFI NTLLLEPEEQ LGTLQLLIYL LPPCNCDTLH RLLQFLSIVA RHADDNISKD GQEVTGNKMT SLNLATIFGP NLLHKQKSSD KEFSVQSSAR AEESTAIIAV VQKMIENYEA LFMVPPDLQN EVLISLLETD PDVVDYLLRR KASQSSSPDM LQSEVSFSVG GRHSSTDSNK ASSGDISPYD NNSPVLSERS LLAMQEDAAP GGSEKLYRVP GQFMLVGHLS SSKSRESSPG PRLGKDLSEE PFDIWGTWHS TLKSGSKDPG MTGSSGDIFE SSSLRAGPCS LSQGNLSPNW PRWQGSPAEL DSDTQGARRT QAAAPATEGR AHPAVSRACS TPHVQVAGKA ERPTARSEQY LTLSGAHDLS ESELDVAGLQ SRATPQCQRP HGSGRDDKRP PPPYPGPGKP AAAAAWIQGP PEGVETPTDQ GGQAAEREQQ VTQKKLSSAN SLPAGEQDSP RLGDAGWLDW QRERWQIWEL LSTDNPDALP ETLV
Genular Protein ID: 3613590312
Symbol: Q59HG6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 729
- Mass: 79761
- Checksum: 7E3F4CAA158408B2
- Sequence:
KAGDGSAAPA AAGALGAHRR RVSWALLSTA LGKPRASPAW HLCLSPFRFP TQSHQRPGRE EEVVLRCSPA EMSAQSLLHS VFSCSSPASS SAASAKGFSK RKLRQTRSLD PALIGGCGSD EAGAEGSARG ATAGRLYSPS LPAESLGPRL ASSSRGPPPR ATRLPPPGPL CSSFSTPSTP QEKSPSGSFH FDYEVPLGRG GLKKSMAWDL PSVLAGPASS RSASSILCSS GGGPNGIFAS PRRWLQQRKF QSPPDSRGHP YVVWKSEGDF TWNSMSGRSV RLRSVPIQSL SELERARLQE VAFYQLQQDC DLSCQITIPK DGQKRKKSLR KKLDSLGKEK NKDKEFIPQA FGMPLSQVIA NDRAYKLKQD LQRDEQKDAS DFVASLLPFG NKRQNKELSS SNSSLSSTSE TPNESTSPNT PEPAPRARRR GAMSVDSITD LDDNQSRLLE ALQLSLPAEA QSKKEKARDK KLSLNPIYRQ VPRLVDSCCQ HLEKHGLQTV GIFRVGSSKK RVRQLREEFD RGIDVSLEEE HSVHDVAALL KEFLRDMPDP LLTRELYTAF INTLLLEPEE QLGTLQLLIY LLPPCNCDTL HRLLQFLSIV ARHADDNISK DGQEVTGNKM TSLNLATIFG PNLLHKQKSS DKEFSVQSSA RAEESTAIIA VVQKMIENYE ALFMVPPDLQ NEVLISLLET DPDVVDYLLR RKASQSSTSS VLPAAVQACP QYPASMFTP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.