Details for: LETM1

Gene ID: 3954

Symbol: LETM1

Ensembl ID: ENSG00000168924

Description: leucine zipper and EF-hand containing transmembrane protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 128.1299
    Cell Significance Index: -19.9300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 87.2091
    Cell Significance Index: -22.1200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 51.0760
    Cell Significance Index: -20.7500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 46.6771
    Cell Significance Index: -24.0100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 21.7650
    Cell Significance Index: -20.7800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 19.2545
    Cell Significance Index: -23.7400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 8.5260
    Cell Significance Index: -22.8400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.1961
    Cell Significance Index: -24.4500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.0330
    Cell Significance Index: -18.5300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.2454
    Cell Significance Index: -11.4800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4001
    Cell Significance Index: 38.1100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0760
    Cell Significance Index: 64.6000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8926
    Cell Significance Index: 97.0900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7731
    Cell Significance Index: 90.1000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7725
    Cell Significance Index: 16.7400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7085
    Cell Significance Index: 115.2300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7010
    Cell Significance Index: 31.7800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6721
    Cell Significance Index: 19.3700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6546
    Cell Significance Index: 591.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6541
    Cell Significance Index: 131.2100
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.6427
    Cell Significance Index: 9.6300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5918
    Cell Significance Index: 16.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5329
    Cell Significance Index: 27.6800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.5223
    Cell Significance Index: 38.9300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4673
    Cell Significance Index: 32.3200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.4520
    Cell Significance Index: 29.1600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4497
    Cell Significance Index: 81.0700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4296
    Cell Significance Index: 85.2500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4283
    Cell Significance Index: 58.8200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4193
    Cell Significance Index: 54.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3793
    Cell Significance Index: 23.9100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3785
    Cell Significance Index: 46.5400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2965
    Cell Significance Index: 106.3500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2826
    Cell Significance Index: 124.9500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2479
    Cell Significance Index: 11.6500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.2171
    Cell Significance Index: 10.1200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2043
    Cell Significance Index: 14.4500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.1821
    Cell Significance Index: 5.2200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1781
    Cell Significance Index: 13.6700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1628
    Cell Significance Index: 88.9100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1386
    Cell Significance Index: 95.8500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0920
    Cell Significance Index: 1.9600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0766
    Cell Significance Index: 7.5800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0545
    Cell Significance Index: 6.9900
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.0437
    Cell Significance Index: 0.2900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0305
    Cell Significance Index: 5.8000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0298
    Cell Significance Index: 0.5100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0293
    Cell Significance Index: 3.4600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0230
    Cell Significance Index: 3.9400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0136
    Cell Significance Index: 9.9800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0091
    Cell Significance Index: 17.1800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0049
    Cell Significance Index: 7.4800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0004
    Cell Significance Index: -0.8100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0059
    Cell Significance Index: -3.7300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0091
    Cell Significance Index: -12.3800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0107
    Cell Significance Index: -8.1100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0271
    Cell Significance Index: -1.8200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0292
    Cell Significance Index: -13.2500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0292
    Cell Significance Index: -21.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0398
    Cell Significance Index: -1.7600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0408
    Cell Significance Index: -2.5100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0415
    Cell Significance Index: -23.3900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0426
    Cell Significance Index: -4.3500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0487
    Cell Significance Index: -30.3900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0504
    Cell Significance Index: -1.7700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0520
    Cell Significance Index: -1.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0634
    Cell Significance Index: -18.2300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0669
    Cell Significance Index: -1.7900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0994
    Cell Significance Index: -14.4500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1097
    Cell Significance Index: -2.9400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1159
    Cell Significance Index: -1.9400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1160
    Cell Significance Index: -13.3000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1209
    Cell Significance Index: -1.6500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1293
    Cell Significance Index: -27.2300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1334
    Cell Significance Index: -3.4300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1376
    Cell Significance Index: -1.6400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1413
    Cell Significance Index: -7.4200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1781
    Cell Significance Index: -6.1900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1936
    Cell Significance Index: -4.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2140
    Cell Significance Index: -6.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2170
    Cell Significance Index: -22.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2181
    Cell Significance Index: -11.3600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.2325
    Cell Significance Index: -5.9400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2373
    Cell Significance Index: -2.1900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2395
    Cell Significance Index: -18.9700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2400
    Cell Significance Index: -13.4700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2808
    Cell Significance Index: -7.0200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3452
    Cell Significance Index: -21.1700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.3500
    Cell Significance Index: -10.2800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3683
    Cell Significance Index: -5.5500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3977
    Cell Significance Index: -11.3500
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.4039
    Cell Significance Index: -5.7500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4067
    Cell Significance Index: -10.8800
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.4099
    Cell Significance Index: -9.4700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4113
    Cell Significance Index: -8.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4286
    Cell Significance Index: -11.2700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4308
    Cell Significance Index: -6.3600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4895
    Cell Significance Index: -15.5900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4957
    Cell Significance Index: -16.2300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4958
    Cell Significance Index: -18.2000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** LETM1 is a transmembrane protein with a unique combination of leucine zipper and EF-hand domains, which confer its ability to interact with calcium ions. Its expression is widespread across various cell types, suggesting its importance in maintaining cellular homeostasis. LETM1 is also involved in regulating cellular responses to hyperosmotic salinity and signaling by rho GTPases, further highlighting its complex role in cellular regulation. **Pathways and Functions:** LETM1 is involved in several pathways that regulate mitochondrial calcium homeostasis, including: 1. **Calcium export from the mitochondrion:** LETM1 acts as a calcium exporter, regulating the concentration of calcium ions within the mitochondria. 2. **Mitochondrial calcium ion homeostasis:** LETM1 maintains the balance of calcium ions within the mitochondria, preventing excessive accumulation or depletion. 3. **Inner mitochondrial membrane organization:** LETM1 contributes to the organization of the inner mitochondrial membrane, ensuring proper calcium ion transport. 4. **Regulation of cellular hyperosmotic salinity response:** LETM1 plays a role in regulating cellular responses to hyperosmotic salinity, which is essential for maintaining cellular homeostasis. 5. **Signaling by rho GTPases:** LETM1 interacts with rho GTPases, regulating signaling pathways involved in cellular regulation. **Clinical Significance:** Dysregulation of LETM1 has been implicated in various diseases, including: 1. **Mitochondrial disorders:** Abnormal expression of LETM1 has been linked to mitochondrial disorders, such as mitochondrial myopathies and encephalopathy. 2. **Cancer:** LETM1 has been identified as a potential biomarker for cancer diagnosis and prognosis. 3. **Neurodegenerative diseases:** LETM1 has been implicated in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. In conclusion, LETM1 is a critical transmembrane protein that regulates mitochondrial calcium homeostasis, maintaining cellular homeostasis and preventing oxidative stress. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms and clinical significance of LETM1.

Genular Protein ID: 2565376657

Symbol: LETM1_HUMAN

Name: Leucine zipper-EF-hand-containing transmembrane protein 1

UniProtKB Accession Codes:

O95202 B4DED2 Q9UF65

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 9 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 Ensembl 1 GO 17 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 1 Rhea 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10486213

Title: LETM1, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, flanks the Wolf-Hirschhorn syndrome (WHS) critical region and is deleted in most WHS patients.

PubMed ID: 10486213

DOI: 10.1006/geno.1999.5881

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14706454

Title: LETM1, a gene deleted in Wolf-Hirschhorn syndrome, encodes an evolutionarily conserved mitochondrial protein.

PubMed ID: 14706454

DOI: 10.1016/j.ygeno.2003.08.013

PubMed ID: 15138253

Title: The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome.

PubMed ID: 15138253

DOI: 10.1074/jbc.m403607200

PubMed ID: 18628306

Title: Characterization of the mitochondrial protein LETM1, which maintains the mitochondrial tubular shapes and interacts with the AAA-ATPase BCS1L.

PubMed ID: 18628306

DOI: 10.1242/jcs.026625

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 19797662

Title: Genome-wide RNAi screen identifies Letm1 as a mitochondrial Ca2+/H+ antiporter.

PubMed ID: 19797662

DOI: 10.1126/science.1175145

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 24898248

Title: NCLX protein, but not LETM1, mediates mitochondrial Ca2+ extrusion, thereby limiting Ca2+-induced NAD(P)H production and modulating matrix redox state.

PubMed ID: 24898248

DOI: 10.1074/jbc.m113.540898

PubMed ID: 24344246

Title: Functional reconstitution of the mitochondrial Ca2+/H+ antiporter Letm1.

PubMed ID: 24344246

DOI: 10.1085/jgp.201311096

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 29123128

Title: PINK1-mediated phosphorylation of LETM1 regulates mitochondrial calcium transport and protects neurons against mitochondrial stress.

PubMed ID: 29123128

DOI: 10.1038/s41467-017-01435-1

PubMed ID: 32139798

Title: The mitochondrial inner membrane protein LETM1 modulates cristae organization through its LETM domain.

PubMed ID: 32139798

DOI: 10.1038/s42003-020-0832-5

PubMed ID: 36321428

Title: TMBIM5 is the Ca2+ /H+ antiporter of mammalian mitochondria.

PubMed ID: 36321428

DOI: 10.15252/embr.202254978

PubMed ID: 36055214

Title: Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement.

PubMed ID: 36055214

DOI: 10.1016/j.ajhg.2022.07.007

Sequence Information:

  • Length: 739
  • Mass: 83354
  • Checksum: 942E9138F299D94F
  • Sequence:
    • MASILLRSCR GRAPARLPPP PRYTVPRGSP GDPAHLSCAS TLGLRNCLNV PFGCCTPIHP 
VYTSSRGDHL GCWALRPECL RIVSRAPWTS TSVGFVAVGP QCLPVRGWHS SRPVRDDSVV 
EKSLKSLKDK NKKLEEGGPV YSPPAEVVVK KSLGQRVLDE LKHYYHGFRL LWIDTKIAAR 
MLWRILNGHS LTRRERRQFL RICADLFRLV PFLVFVVVPF MEFLLPVAVK LFPNMLPSTF 
ETQSLKEERL KKELRVKLEL AKFLQDTIEE MALKNKAAKG SATKDFSVFF QKIRETGERP 
SNEEIMRFSK LFEDELTLDN LTRPQLVALC KLLELQSIGT NNFLRFQLTM RLRSIKADDK 
LIAEEGVDSL NVKELQAACR ARGMRALGVT EDRLRGQLKQ WLDLHLHQEI PTSLLILSRA 
MYLPDTLSPA DQLKSTLQTL PEIVAKEAQV KVAEVEGEQV DNKAKLEATL QEEAAIQQEH 
REKELQKRSE VAKDFEPERV VAAPQRPGTE PQPEMPDTVL QSETLKDTAP VLEGLKEEEI 
TKEEIDILSD ACSKLQEQKK SLTKEKEELE LLKEDVQDYS EDLQEIKKEL SKTGEEKYVE 
ESKASKRLTK RVQQMIGQID GLISQLEMDQ QAGKLAPANG MPTGENVISV AELINAMKQV 
KHIPESKLTS LAAALDENKD GKVNIDDLVK VIELVDKEDV HISTSQVAEI VATLEKEEKV 
EEKEKAKEKA EKEVAEVKS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.