Details for: STS
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 106.5928
Cell Significance Index: -16.5800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 65.6433
Cell Significance Index: -16.6500 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 42.4326
Cell Significance Index: -17.4800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 33.5994
Cell Significance Index: -13.6500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 14.2447
Cell Significance Index: -13.6000 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.4392
Cell Significance Index: -16.5700 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 5.3993
Cell Significance Index: 144.1700 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.2270
Cell Significance Index: -16.6800 - Cell Name: trophoblast giant cell (CL0002488)
Fold Change: 1.6559
Cell Significance Index: 11.9300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.5126
Cell Significance Index: 66.9100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.3790
Cell Significance Index: 52.2200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.1820
Cell Significance Index: 224.9500 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.1458
Cell Significance Index: 59.5200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 1.0416
Cell Significance Index: 373.6100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.9399
Cell Significance Index: 188.5400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.9339
Cell Significance Index: 8.6000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6258
Cell Significance Index: 61.9100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.5915
Cell Significance Index: 33.1900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5413
Cell Significance Index: 88.0400 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.5035
Cell Significance Index: 6.2500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4892
Cell Significance Index: 441.7300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2777
Cell Significance Index: 6.0800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2740
Cell Significance Index: 29.8100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.2252
Cell Significance Index: 13.8400 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1780
Cell Significance Index: 4.2700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1753
Cell Significance Index: 11.7900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1681
Cell Significance Index: 10.0900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1556
Cell Significance Index: 3.8900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1352
Cell Significance Index: 2.9300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.1325
Cell Significance Index: 244.3000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1322
Cell Significance Index: 10.1500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1040
Cell Significance Index: 7.2000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0989
Cell Significance Index: 17.8300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0743
Cell Significance Index: 114.4500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0709
Cell Significance Index: 14.0700 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0708
Cell Significance Index: 38.6800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0611
Cell Significance Index: 7.5200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0604
Cell Significance Index: 82.0700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0593
Cell Significance Index: 37.0400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0558
Cell Significance Index: 38.6000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0448
Cell Significance Index: 2.0300 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.0433
Cell Significance Index: 0.5400 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0405
Cell Significance Index: 76.2200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0363
Cell Significance Index: 23.0700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0361
Cell Significance Index: 2.3300 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0273
Cell Significance Index: 12.3800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0183
Cell Significance Index: 3.1200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0026
Cell Significance Index: 0.0800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0052
Cell Significance Index: -0.5900 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0060
Cell Significance Index: -0.2800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0073
Cell Significance Index: -5.3900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0136
Cell Significance Index: -1.9800 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0165
Cell Significance Index: -9.3000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0182
Cell Significance Index: -13.8000 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0190
Cell Significance Index: -13.9200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0195
Cell Significance Index: -0.6900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0203
Cell Significance Index: -0.4300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0214
Cell Significance Index: -9.4700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0305
Cell Significance Index: -4.1900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0309
Cell Significance Index: -3.5400 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0392
Cell Significance Index: -1.1200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0433
Cell Significance Index: -9.1300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0463
Cell Significance Index: -13.3300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0541
Cell Significance Index: -6.9400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0584
Cell Significance Index: -6.8100 - Cell Name: syncytiotrophoblast cell (CL0000525)
Fold Change: -0.0684
Cell Significance Index: -0.6500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0789
Cell Significance Index: -4.8400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0888
Cell Significance Index: -10.4700 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.1022
Cell Significance Index: -1.2900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1055
Cell Significance Index: -10.7800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1191
Cell Significance Index: -15.3900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.1271
Cell Significance Index: -1.8200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1366
Cell Significance Index: -2.9100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1445
Cell Significance Index: -15.0500 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.1626
Cell Significance Index: -2.4500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1639
Cell Significance Index: -3.2400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1658
Cell Significance Index: -3.4400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1889
Cell Significance Index: -6.0500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1893
Cell Significance Index: -14.1100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1898
Cell Significance Index: -8.9200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1910
Cell Significance Index: -15.1300 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2025
Cell Significance Index: -12.7600 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.2052
Cell Significance Index: -4.1200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2104
Cell Significance Index: -2.8700 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.2211
Cell Significance Index: -7.2400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2217
Cell Significance Index: -5.7000 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -0.2275
Cell Significance Index: -2.3700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2316
Cell Significance Index: -16.3800 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.2354
Cell Significance Index: -2.2400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2430
Cell Significance Index: -6.7900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2469
Cell Significance Index: -12.8600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2491
Cell Significance Index: -13.0800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.2619
Cell Significance Index: -8.3400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2940
Cell Significance Index: -14.8600 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.3147
Cell Significance Index: -7.8500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3231
Cell Significance Index: -6.9800 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3266
Cell Significance Index: -11.4400 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.3664
Cell Significance Index: -3.8300 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.3985
Cell Significance Index: -17.3300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4004
Cell Significance Index: -14.7000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3140493300
Symbol: STS_HUMAN
Name: Steryl-sulfatase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2668275
Title: Cloning and expression of human steroid-sulfatase. Membrane topology, glycosylation, and subcellular distribution in BHK-21 cells.
PubMed ID: 2668275
PubMed ID: 3032454
Title: Cloning and expression of steroid sulfatase cDNA and the frequent occurrence of deletions in STS deficiency: implications for X-Y interchange.
PubMed ID: 3032454
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3203382
Title: The human X-linked steroid sulfatase gene and a Y-encoded pseudogene: evidence for an inversion of the Y chromosome during primate evolution.
PubMed ID: 3203382
PubMed ID: 2765556
Title: Characterization of rat and human steroid sulfatases.
PubMed ID: 2765556
PubMed ID: 12657638
Title: Structure of human estrone sulfatase suggests functional roles of membrane association.
PubMed ID: 12657638
PubMed ID: 1539590
Title: Identification of point mutations in the steroid sulfatase gene of three patients with X-linked ichthyosis.
PubMed ID: 1539590
PubMed ID: 9252398
Title: Characterization of point mutations in patients with X-linked ichthyosis. Effects on the structure and function of the steroid sulfatase protein.
PubMed ID: 9252398
PubMed ID: 10679952
Title: PCR diagnosis of X-linked ichthyosis: identification of a novel mutation (E560P) of the steroid sulfatase gene.
PubMed ID: 10679952
DOI: 10.1002/(sici)1098-1004(200003)15:3<296::aid-humu17>3.0.co;2-#
PubMed ID: 10844566
Title: Novel point mutations in the steroid sulfatase gene in patients with X-linked ichthyosis: transfection analysis using the mutated genes.
PubMed ID: 10844566
PubMed ID: 23466819
Title: Functional characterization of seven single-nucleotide polymorphisms of the steroid sulfatase gene found in a Japanese population.
PubMed ID: 23466819
DOI: 10.1038/jhg.2013.12
Sequence Information:
- Length: 583
- Mass: 65492
- Checksum: 74746AFA9D21A0A6
- Sequence:
MPLRKMKIPF LLLFFLWEAE SHAASRPNII LVMADDLGIG DPGCYGNKTI RTPNIDRLAS GGVKLTQHLA ASPLCTPSRA AFMTGRYPVR SGMASWSRTG VFLFTASSGG LPTDEITFAK LLKDQGYSTA LIGKWHLGMS CHSKTDFCHH PLHHGFNYFY GISLTNLRDC KPGEGSVFTT GFKRLVFLPL QIVGVTLLTL AALNCLGLLH VPLGVFFSLL FLAALILTLF LGFLHYFRPL NCFMMRNYEI IQQPMSYDNL TQRLTVEAAQ FIQRNTETPF LLVLSYLHVH TALFSSKDFA GKSQHGVYGD AVEEMDWSVG QILNLLDELR LANDTLIYFT SDQGAHVEEV SSKGEIHGGS NGIYKGGKAN NWEGGIRVPG ILRWPRVIQA GQKIDEPTSN MDIFPTVAKL AGAPLPEDRI IDGRDLMPLL EGKSQRSDHE FLFHYCNAYL NAVRWHPQNS TSIWKAFFFT PNFNPVGSNG CFATHVCFCF GSYVTHHDPP LLFDISKDPR ERNPLTPASE PRFYEILKVM QEAADRHTQT LPEVPDQFSW NNFLWKPWLQ LCCPSTGLSC QCDREKQDKR LSR
Genular Protein ID: 1705756864
Symbol: A6PYA4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 17601726
Title: The expression of the human steroid sulfatase-encoding gene is driven by alternative first exons.
PubMed ID: 17601726
Sequence Information:
- Length: 8
- Mass: 974
- Checksum: FE272729D7605336
- Sequence:
MKIPFLLL
Genular Protein ID: 1091401694
Symbol: Q0W975_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16837617
Title: Tissue-specific transcriptional initiation and activity of steroid sulfatase complementing dehydroepiandrosterone sulfate uptake and intracrine steroid activations in human adipose tissue.
PubMed ID: 16837617
DOI: 10.1677/joe.1.06811
PubMed ID: 17601726
Title: The expression of the human steroid sulfatase-encoding gene is driven by alternative first exons.
PubMed ID: 17601726
PubMed ID: 19429462
Title: Transcriptional control of human steroid sulfatase.
PubMed ID: 19429462
Sequence Information:
- Length: 20
- Mass: 2390
- Checksum: 1AEB7F5B9668580D
- Sequence:
MAQDRLQLFI AKMKIPFLLL
Genular Protein ID: 1356757835
Symbol: A0A590UJL0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15772651
Sequence Information:
- Length: 578
- Mass: 64866
- Checksum: A07431F8A5E7C6CC
- Sequence:
MKIPFLLLFF LWEAESHAAS RPNIILVMAD DLGIGDPGCY GNKTIRTPNI DRLASGGVKL TQHLAASPLC TPSRAAFMTG RYPVRSGMAS WSRTGVFLFT ASSGGLPTDE ITFAKLLKDQ GYSTALIGKW HLGMSCHSKT DFCHHPLHHG FNYFYGISLT NLRDCKPGEG SVFTTGFKRL VFLPLQIVGV TLLTLAALNC LGLLHVPLGV FFSLLFLAAL ILTLFLGFLH YFRPLNCFMM RNYEIIQQPM SYDNLTQRLT VEAAQFIQRN TETPFLLVLS YLHVHTALFS SKDFAGKSQH GVYGDAVEEM DWSVGQILNL LDELRLANDT LIYFTSDQGA HVEEVSSKGE IHGGSNGIYK GGKANNWEGG IRVPGILRWP RVIQAGQKID EPTSNMDIFP TVAKLAGAPL PEDRIIDGRD LMPLLEGKSQ RSDHEFLFHY CNAYLNAVRW HPQNSTSIWK AFFFTPNFNP VGSNGCFATH VCFCFGSYVT HHDPPLLFDI SKDPRERNPL TPASEPRFYE ILKVMQEAAD RHTQTLPEVP DQFSWNNFLW KPWLQLCCPS TGLSCQCDRE KQDKRLSR
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.