Details for: MIA2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 83.0928
Cell Significance Index: -39.2300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 79.7894
Cell Significance Index: -32.4200 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 72.7276
Cell Significance Index: -37.4100 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 58.4630
Cell Significance Index: -39.2300 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 34.3496
Cell Significance Index: -32.8000 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 14.1161
Cell Significance Index: -37.8200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.3057
Cell Significance Index: 457.5800 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.8260
Cell Significance Index: 109.6200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.7091
Cell Significance Index: 342.8500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.4978
Cell Significance Index: 38.5000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.3859
Cell Significance Index: 106.3600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.2864
Cell Significance Index: 27.8700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.2011
Cell Significance Index: 34.6100 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.0589
Cell Significance Index: 26.4700 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9703
Cell Significance Index: 348.0300 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.9647
Cell Significance Index: 36.5300 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.9642
Cell Significance Index: 42.6500 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.8316
Cell Significance Index: 20.2900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7826
Cell Significance Index: 706.6200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.7357
Cell Significance Index: 80.0300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.7149
Cell Significance Index: 205.7100 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.6081
Cell Significance Index: 5.6000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5997
Cell Significance Index: 108.1000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.5288
Cell Significance Index: 35.5600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5151
Cell Significance Index: 63.3400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 0.5129
Cell Significance Index: 18.8300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.5088
Cell Significance Index: 23.0600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.4809
Cell Significance Index: 22.4200 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.4746
Cell Significance Index: 8.0000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4464
Cell Significance Index: 84.9500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.4398
Cell Significance Index: 24.6800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.4068
Cell Significance Index: 21.1900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.4046
Cell Significance Index: 8.8600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.3809
Cell Significance Index: 10.8700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.3365
Cell Significance Index: 17.4800 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 0.2885
Cell Significance Index: 2.9100 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.2831
Cell Significance Index: 28.0000 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.2418
Cell Significance Index: 4.7200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.2405
Cell Significance Index: 27.5600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2228
Cell Significance Index: 38.0400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2095
Cell Significance Index: 133.0800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1991
Cell Significance Index: 7.0000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1937
Cell Significance Index: 12.2100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1644
Cell Significance Index: 72.6800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1540
Cell Significance Index: 289.9200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.1524
Cell Significance Index: 69.1500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1459
Cell Significance Index: 6.8600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1028
Cell Significance Index: 56.1600 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0963
Cell Significance Index: 12.3500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.0850
Cell Significance Index: 5.4900 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0605
Cell Significance Index: 1.6900 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0568
Cell Significance Index: 87.4500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0405
Cell Significance Index: 74.6200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0279
Cell Significance Index: 3.8300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0270
Cell Significance Index: 19.7600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0213
Cell Significance Index: 1.3100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0027
Cell Significance Index: -3.7200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0146
Cell Significance Index: -10.8200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0168
Cell Significance Index: -10.5200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0254
Cell Significance Index: -0.4400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0351
Cell Significance Index: -26.5400 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0392
Cell Significance Index: -22.1000 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.0485
Cell Significance Index: -0.6800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0757
Cell Significance Index: -11.0000 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0937
Cell Significance Index: -12.1100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0954
Cell Significance Index: -20.0900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1087
Cell Significance Index: -8.1100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1168
Cell Significance Index: -11.9300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1221
Cell Significance Index: -2.6000 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1499
Cell Significance Index: -10.6000 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1599
Cell Significance Index: -2.3600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2168
Cell Significance Index: -25.2700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.2535
Cell Significance Index: -6.9000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2564
Cell Significance Index: -26.7000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.2595
Cell Significance Index: -3.5400 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3041
Cell Significance Index: -34.7100 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.3086
Cell Significance Index: -4.9800 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.3597
Cell Significance Index: -5.1200 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: -0.3891
Cell Significance Index: -5.8300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3934
Cell Significance Index: -8.1600 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4067
Cell Significance Index: -32.2100 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.4091
Cell Significance Index: -5.8800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.4168
Cell Significance Index: -11.1500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.4307
Cell Significance Index: -11.5000 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.4426
Cell Significance Index: -8.1800 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: -0.4749
Cell Significance Index: -6.8300 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.5115
Cell Significance Index: -3.9100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.5306
Cell Significance Index: -27.8600 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.5785
Cell Significance Index: -8.7200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5866
Cell Significance Index: -18.7900 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.5980
Cell Significance Index: -7.5300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6139
Cell Significance Index: -37.6400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6565
Cell Significance Index: -20.9100 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.6629
Cell Significance Index: -19.4700 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.6953
Cell Significance Index: -19.9300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6970
Cell Significance Index: -22.8200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.7080
Cell Significance Index: -8.4400 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.7232
Cell Significance Index: -8.9700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.7458
Cell Significance Index: -7.7200 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.7473
Cell Significance Index: -15.8600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3426420081
Symbol: MIA2_HUMAN
Name: Cutaneous T-cell lymphoma-associated antigen 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9356211
Title: cDNA cloning and chromosomal mapping of a predicted coiled-coil proline-rich protein immunogenic in meningioma patients.
PubMed ID: 9356211
PubMed ID: 12839582
Title: cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.
PubMed ID: 12839582
PubMed ID: 27138255
Title: TANGO1 and Mia2/cTAGE5 (TALI) cooperate to export bulky pre-chylomicrons/VLDLs from the endoplasmic reticulum.
PubMed ID: 27138255
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 12586826
Title: Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.
PubMed ID: 12586826
PubMed ID: 21807889
Title: Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.
PubMed ID: 21807889
DOI: 10.1194/jlr.m017277
PubMed ID: 21525241
Title: cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites.
PubMed ID: 21525241
PubMed ID: 25202031
Title: Concentration of Sec12 at ER exit sites via interaction with cTAGE5 is required for collagen export.
PubMed ID: 25202031
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 27170179
Title: Dual function of cTAGE5 in collagen export from the endoplasmic reticulum.
PubMed ID: 27170179
PubMed ID: 27551091
Title: TANGO1/cTAGE5 receptor as a polyvalent template for assembly of large COPII coats.
PubMed ID: 27551091
PubMed ID: 28442536
Title: TANGO1 recruits Sec16 to coordinately organize ER exit sites for efficient secretion.
PubMed ID: 28442536
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 1412
- Mass: 159836
- Checksum: E870056BF9D5A0B2
- Sequence:
MAKFGVHRIL LLAISLTKCL ESTKLLADLK KCGDLECEAL INRVSAMRDY RGPDCRYLNF TKGEEISVYV KLAGEREDLW AGSKGKEFGY FPRDAVQIEE VFISEEIQMS TKESDFLCLL GVSYTFDNED SELNGDYGEN IYPYEEDKDE KSSIYESDFQ IEPGFYATYE STLFEDQVPA LEAPEDIGST SESKDWEEVV VESMEQDRIP EVHVPPSSAV SGVKEWFGLG GEQAEEKAFE SVIEPVQESS FRSRKIAVED ENDLEELNNG EPQTEHQQES ESEIDSVPKT QSELASESEH IPKPQSTGWF GGGFTSYLGF GDEDTGLELI AEESNPPLQD FPNSISSDKE ATVPCTEILT EKKDTITNDS LSLKPSWFDF GFAILGFAYA KEDKIMLDDR KNEEDGGADE HEHPLTSELD PEKEQEIETI KIIETEDQID KKPVSEKTDE SDTIPYLKKF LYNFDNPWNF QNIPKETELP FPKQILDQNN VIENEETGEF SIDNYPTDNT KVMIFKSSYS LSDMVSNIEL PTRIHEEVYF EPSSSKDSDE NSKPSVDTEG PALVEIDRSV ENTLLNSQMV STDNSLSSQN YISQKEDASE FQILKYLFQI DVYDFMNSAF SPIVILTERV VAALPEGMRP DSNLYGFPWE LVICAAVVGF FAVLFFLWRS FRSVRSRLYV GREKKLALML SGLIEEKSKL LEKFSLVQKE YEGYEVESSL KDASFEKEAT EAQSLEATCE KLNRSNSELE DEILCLEKEL KEEKSKHSEQ DELMADISKR IQSLEDESKS LKSQVAEAKM TFKIFQMNEE RLKIAIKDAL NENSQLQESQ KQLLQEAEVW KEQVSELNKQ KVTFEDSKVH AEQVLNDKES HIKTLTERLL KMKDWAAMLG EDITDDDNLE LEMNSESENG AYLDNPPKGA LKKLIHAAKL NASLKTLEGE RNQIYIQLSE VDKTKEELTE HIKNLQTEQA SLQSENTHFE NENQKLQQKL KVMTELYQEN EMKLHRKLTV EENYRLEKEE KLSKVDEKIS HATEELETYR KRAKDLEEEL ERTIHSYQGQ IISHEKKAHD NWLAARNAER NLNDLRKENA HNRQKLTETE LKFELLEKDP YALDVPNTAF GREHSPYGPS PLGWPSSETR AFLSPPTLLE GPLRLSPLLP GGGGRGSRGP GNPLDHQITN ERGESSCDRL TDPHRAPSDT GSLSPPWDQD RRMMFPPPGQ SYPDSALPPQ RQDRFCSNSG RLSGPAELRS FNMPSLDKMD GSMPSEMESS RNDTKDDLGN LNVPDSSLPA ENEATGPGFV PPPLAPIRGP LFPVDARGPF LRRGPPFPPP PPGAMFGASR DYFPPGDFPG PPPAPFAMRN VYPPRGFPPY LPPRPGFFPP PPHSEGRSEF PSGLIPPSNE PATEHPEPQQ ET
Genular Protein ID: 1547945710
Symbol: Q4G155_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 395
- Mass: 45539
- Checksum: 52C9724425038667
- Sequence:
MEEPGATPQP YLGLLLEELR RVVAALPEGM RPDSNLYGFP WELVICAAVV GFFAVLFFLW RSFRSVRSRL YVGREKKLAL MLSGLIEEKS KLLEKFSLVQ KEYEGYEVES SLKDASFEKE ATEAQSLEAT CEKLNRSNSE LEDEILCLEK ELKEEKSKHS EQDELMADIS KRIQSLEDES KSLKSQVAEA KMTFKIFQMN EERLKIAIKD ALNENSQLQE SQKQLLQEAE VWKEQVSELN KQKVTFEDSK VHAEQVLNDK ESHIKTLTER LLKMKDWAAM LGEDITDDDN LELEMNSESE NGAYLDNPPK GALKKLIHAA KLNASLKTLE GERNQIYIQL SEVDKTKEEL TEHIKNLQAQ QASLQSENTH FENENQKLQQ KLKVMTELYQ EKKKK
Genular Protein ID: 1257248190
Symbol: Q59FD2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 808
- Mass: 91743
- Checksum: 555D20BA2FD9365D
- Sequence:
TCTYVCNQYF YQKYIFKNLL FFILKVVAAL PEGMRPDSNL YGFPWELVIC AAVVGFFAVL FFLWRSFRSV RSRLYVGREK KLALMLSGLI EEKSKLLEKF SLVQKEYEGY EVESSLKDAS FEKEATEAQS LEATCEKLNR SNSELEDEIL CLEKELKEEK SKHSEQDELM ADISKRIQSL EDESKSLKSQ VAEAKMTFKI FQMNEERLKI AIKDALNENS QLQESQKQLL QEAEVWKEQV SELNKQKVTF EDSKVHAEQV LNDKESHIKT LTERLLKMKD WAAMLGEDIT DDDNLELEMN SESENGAYLD NPPKGALKKL IHAAKLNASL KTLEGERNQI YIQLSEVDKT KEELTEHIKN LQTEQASLQS ENTHFENENQ KLQQKLKVMT ELYQENEMKL HRKLTVEENY RLEKEEKLSK VDEKISHATE ELETYRKRAK DLEEELERTI HSYQGQIISH EKKAHDNWLA ARNAERNLND LRKENAHNRQ KLTETELKFE LLEKDPYALD VPNTAFGREH SPYGPSPLGW PSSETRAFLS PPTLLEGPLR LSPLLPGGGG RGSRGPGNPL DHQITNERGE SSCDRLTDPH RAPSDTGSLS PPWDQDRRMM FPPPGQSYPD SALPPQRQDR FCSNSGRLSG PAELRSFNMP SLDKMDGSMP SEMESSRNDT KDDLGNLNVP DSSLPAENEA TGPGFVPPPL APVRGPLFPV DARGPFLRRG PPFPPPPPGA MFGASRDYFP PGDFPGPPPA PFAMRNVYPP RGFPPYLPPR PGFFPPPPHS EGRSEFPSGL IPPSNEPATE HPEPQQET
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.