Details for: NFATC2

Gene ID: 4773

Symbol: NFATC2

Ensembl ID: ENSG00000101096

Description: nuclear factor of activated T cells 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 115.7863
    Cell Significance Index: -18.0100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 63.3961
    Cell Significance Index: -16.0800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 48.2822
    Cell Significance Index: -19.6200
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 44.3105
    Cell Significance Index: -20.9200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.2885
    Cell Significance Index: -18.8500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.8686
    Cell Significance Index: -18.4000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 6.2365
    Cell Significance Index: -19.1600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.2317
    Cell Significance Index: -11.4500
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.8542
    Cell Significance Index: -19.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.9640
    Cell Significance Index: 389.7600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.8202
    Cell Significance Index: 80.5100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.7273
    Cell Significance Index: 65.4100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.7218
    Cell Significance Index: 14.0400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0304
    Cell Significance Index: 101.9300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9853
    Cell Significance Index: 160.2600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.5937
    Cell Significance Index: 69.1900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5780
    Cell Significance Index: 62.8700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.5591
    Cell Significance Index: 16.4200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5172
    Cell Significance Index: 31.0500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.4619
    Cell Significance Index: 6.9600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.4397
    Cell Significance Index: 51.8600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.4124
    Cell Significance Index: 53.2800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.3764
    Cell Significance Index: 9.4100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3633
    Cell Significance Index: 10.4200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3322
    Cell Significance Index: 25.5000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2836
    Cell Significance Index: 19.6200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.2665
    Cell Significance Index: 1.6100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.2270
    Cell Significance Index: 4.4300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2263
    Cell Significance Index: 6.5200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.2020
    Cell Significance Index: 9.5000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.1979
    Cell Significance Index: 123.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1629
    Cell Significance Index: 73.9500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1579
    Cell Significance Index: 30.0500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1083
    Cell Significance Index: 4.9100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0901
    Cell Significance Index: 16.2500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0809
    Cell Significance Index: 55.9800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0682
    Cell Significance Index: 61.5500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0462
    Cell Significance Index: 1.0000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0257
    Cell Significance Index: 14.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0149
    Cell Significance Index: 28.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0120
    Cell Significance Index: 2.4100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0099
    Cell Significance Index: 6.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0097
    Cell Significance Index: 1.6500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0068
    Cell Significance Index: 0.2400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0055
    Cell Significance Index: 1.9700
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 0.0023
    Cell Significance Index: 0.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0054
    Cell Significance Index: -10.0400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0063
    Cell Significance Index: -0.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0079
    Cell Significance Index: -1.0900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0080
    Cell Significance Index: -12.3400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0093
    Cell Significance Index: -6.9200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0130
    Cell Significance Index: -17.7300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0139
    Cell Significance Index: -7.8200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0204
    Cell Significance Index: -2.1200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0240
    Cell Significance Index: -18.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0252
    Cell Significance Index: -18.5100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0309
    Cell Significance Index: -13.6700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0366
    Cell Significance Index: -5.3200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0435
    Cell Significance Index: -4.4400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0444
    Cell Significance Index: -2.0700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0469
    Cell Significance Index: -13.5000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0486
    Cell Significance Index: -5.9700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0502
    Cell Significance Index: -10.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0695
    Cell Significance Index: -7.9700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0710
    Cell Significance Index: -8.1100
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.0881
    Cell Significance Index: -1.1100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1091
    Cell Significance Index: -7.0400
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1111
    Cell Significance Index: -2.8600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1131
    Cell Significance Index: -14.5000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1221
    Cell Significance Index: -2.6000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1414
    Cell Significance Index: -10.5400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.1681
    Cell Significance Index: -2.9700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1923
    Cell Significance Index: -5.1400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2038
    Cell Significance Index: -2.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2194
    Cell Significance Index: -13.4500
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2209
    Cell Significance Index: -2.5100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.2231
    Cell Significance Index: -11.5900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2445
    Cell Significance Index: -13.7200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2468
    Cell Significance Index: -7.9100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2582
    Cell Significance Index: -6.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2621
    Cell Significance Index: -20.7600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2665
    Cell Significance Index: -7.1300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2669
    Cell Significance Index: -3.9400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2763
    Cell Significance Index: -18.5800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2939
    Cell Significance Index: -14.8500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.3121
    Cell Significance Index: -5.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3184
    Cell Significance Index: -4.5600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3254
    Cell Significance Index: -20.5100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3283
    Cell Significance Index: -6.8100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.3285
    Cell Significance Index: -20.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.3362
    Cell Significance Index: -9.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.3471
    Cell Significance Index: -9.7000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3544
    Cell Significance Index: -5.9700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3605
    Cell Significance Index: -12.6300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3732
    Cell Significance Index: -19.4400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3775
    Cell Significance Index: -6.4700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3904
    Cell Significance Index: -8.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4254
    Cell Significance Index: -13.5500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.4368
    Cell Significance Index: -5.9600
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.4621
    Cell Significance Index: -7.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family, which is a group of transcription factors involved in the regulation of immune responses. NFATC2 is characterized by its ability to bind to DNA and RNA polymerase II-specific transcription activators, and its expression is significantly observed in various cell types. Some key characteristics of NFATC2 include: * Transcriptional regulation by RNA polymerase II * Binding to DNA and RNA polymerase II-specific transcription activators * Expression in various cell types, including immune cells, neural cells, and endothelial cells * Role in the regulation of immune responses, cell migration, and development **Pathways and Functions** NFATC2 is involved in several cellular pathways and functions, including: * **Calcineurin-NFAT signaling cascade**: NFATC2 is activated by calcineurin, a protein phosphatase that dephosphorylates NFATC2, allowing it to bind to DNA and regulate transcription. * **Adaptive immune system**: NFATC2 regulates the expression of genes involved in the adaptive immune system, including those involved in T-cell activation and cytokine production. * **Innate immune system**: NFATC2 also regulates the expression of genes involved in the innate immune system, including those involved in the recognition of pathogens and the production of cytokines. * **Cell migration**: NFATC2 regulates the expression of genes involved in cell migration, including those involved in the movement of immune cells and neural cells. * **Development**: NFATC2 is involved in the regulation of development, including the development of immune cells and neural cells. **Clinical Significance** NFATC2 has been implicated in several diseases and disorders, including: * **Autoimmune diseases**: NFATC2 has been implicated in the regulation of autoimmune diseases, including rheumatoid arthritis and multiple sclerosis. * **Cancer**: NFATC2 has been implicated in the regulation of cancer cell growth and survival. * **Neurological disorders**: NFATC2 has been implicated in the regulation of neurological disorders, including Alzheimer's disease and Parkinson's disease. * **Infectious diseases**: NFATC2 has been implicated in the regulation of infectious diseases, including HIV and tuberculosis. In conclusion, NFATC2 is a transcription factor that plays a crucial role in the regulation of various cellular processes, including immune responses, cell migration, and development. Its expression is significantly observed in various cell types, and it has been implicated in several diseases and disorders. Further research is needed to fully understand the role of NFATC2 in human health and disease.

Genular Protein ID: 3866904036

Symbol: NFAC2_HUMAN

Name: Nuclear factor of activated T-cells, cytoplasmic 2

UniProtKB Accession Codes:

Q13469 B5B2N8 B5B2N9 B5B2P0 B5B2P2 B5B2P3 Q13468 Q5TFW7 Q5TFW8 Q9NPX6 Q9NQH3 Q9UJR2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 ELM 1 EMBL 15 Ensembl 6 EvolutionaryTrace 1 GO 35 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 4 RefSeq 6 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8668213

Title: Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes.

PubMed ID: 8668213

DOI: 10.1128/mcb.16.7.3955

PubMed ID: 18675896

Title: Alternative splicing and expression of human and mouse NFAT genes.

PubMed ID: 18675896

DOI: 10.1016/j.ygeno.2008.06.011

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10089876

Title: Generic signals and specific outcomes: signaling through Ca2+, calcineurin, and NF-AT.

PubMed ID: 10089876

DOI: 10.1016/s0092-8674(00)80571-1

PubMed ID: 15144186

Title: Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

PubMed ID: 15144186

DOI: 10.1021/ac035352d

PubMed ID: 15790681

Title: Foxp3 interacts with nuclear factor of activated T cells and NF-kappa B to repress cytokine gene expression and effector functions of T helper cells.

PubMed ID: 15790681

DOI: 10.1073/pnas.0501675102

PubMed ID: 17467953

Title: Nine-amino-acid transactivation domain: establishment and prediction utilities.

PubMed ID: 17467953

DOI: 10.1016/j.ygeno.2007.02.003

PubMed ID: 18218901

Title: NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins.

PubMed ID: 18218901

DOI: 10.1126/science.1151227

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21871017

Title: NFAT promotes carcinoma invasive migration through glypican-6.

PubMed ID: 21871017

DOI: 10.1042/bj20110530

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26248042

Title: Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization.

PubMed ID: 26248042

DOI: 10.1371/journal.pone.0134569

PubMed ID: 26766444

Title: Endothelial RSPO3 controls vascular stability and pruning through non-canonical WNT/Ca(2+)/NFAT signaling.

PubMed ID: 26766444

DOI: 10.1016/j.devcel.2015.12.015

PubMed ID: 35789258

Title: Human complete NFAT1 deficiency causes a triad of joint contractures, osteochondromas, and B-cell malignancy.

PubMed ID: 35789258

DOI: 10.1182/blood.2022015674

PubMed ID: 21458306

Title: Structure of a domain-swapped FOXP3 dimer on DNA and its function in regulatory T cells.

PubMed ID: 21458306

DOI: 10.1016/j.immuni.2011.02.017

Sequence Information:

  • Length: 925
  • Mass: 100146
  • Checksum: 8DAE86855CCB58D3
  • Sequence:
    • MNAPERQPQP DGGDAPGHEP GGSPQDELDF SILFDYEYLN PNEEEPNAHK VASPPSGPAY 
PDDVLDYGLK PYSPLASLSG EPPGRFGEPD RVGPQKFLSA AKPAGASGLS PRIEITPSHE 
LIQAVGPLRM RDAGLLVEQP PLAGVAASPR FTLPVPGFEG YREPLCLSPA SSGSSASFIS 
DTFSPYTSPC VSPNNGGPDD LCPQFQNIPA HYSPRTSPIM SPRTSLAEDS CLGRHSPVPR 
PASRSSSPGA KRRHSCAEAL VALPPGASPQ RSRSPSPQPS SHVAPQDHGS PAGYPPVAGS 
AVIMDALNSL ATDSPCGIPP KMWKTSPDPS PVSAAPSKAG LPRHIYPAVE FLGPCEQGER 
RNSAPESILL VPPTWPKPLV PAIPICSIPV TASLPPLEWP LSSQSGSYEL RIEVQPKPHH 
RAHYETEGSR GAVKAPTGGH PVVQLHGYME NKPLGLQIFI GTADERILKP HAFYQVHRIT 
GKTVTTTSYE KIVGNTKVLE IPLEPKNNMR ATIDCAGILK LRNADIELRK GETDIGRKNT 
RVRLVFRVHI PESSGRIVSL QTASNPIECS QRSAHELPMV ERQDTDSCLV YGGQQMILTG 
QNFTSESKVV FTEKTTDGQQ IWEMEATVDK DKSQPNMLFV EIPEYRNKHI RTPVKVNFYV 
INGKRKRSQP QHFTYHPVPA IKTEPTDEYD PTLICSPTHG GLGSQPYYPQ HPMVAESPSC 
LVATMAPCQQ FRTGLSSPDA RYQQQNPAAV LYQRSKSLSP SLLGYQQPAL MAAPLSLADA 
HRSVLVHAGS QGQSSALLHP SPTNQQASPV IHYSPTNQQL RCGSHQEFQH IMYCENFAPG 
TTRPGPPPVS QGQRLSPGSY PTVIQQQNAT SQRAAKNGPP VSDQKEVLPA GVTIKQEQNL 
DQTYLDDVNE IIRKEFSGPP ARNQT

Genular Protein ID: 1732163845

Symbol: B5B2P4_HUMAN

Name: N/A

UniProtKB Accession Codes:

B5B2P4

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 4 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 18675896

Title: Alternative splicing and expression of human and mouse NFAT genes.

PubMed ID: 18675896

DOI: 10.1016/j.ygeno.2008.06.011

Sequence Information:

  • Length: 706
  • Mass: 77061
  • Checksum: 69EA7AAB0EC54634
  • Sequence:
    • MSPRTSLAED SCLGRHSPVP RPASRSSSPG AKRRHSCAEA LVALPPGASP QRSRSPSPQP 
SSHVAPQDHG SPAGYPPVAG SAVIMDALNS LATDSPCGIP PKMWKTSPDP SPVSAAPSKA 
GLPRHIYPAV EFLGPCEQGE RRNSAPESIL LVPPTWPKPL VPAIPICSIP VTASLPPLEW 
PLSSQSGSYE LRIEVQPKPH HRAHYETEGS RGAVKAPTGG HPVVQLHGYM ENKPLGLQIF 
IGTADERILK PHAFYQVHRI TGKTVTTTSY EKIVGNTKVL EIPLEPKNNM RATIDCAGIL 
KLRNADIELR KGETDIGRKN TRVRLVFRVH IPESSGRIVS LQTASNPIEC SQRSAHELPM 
VERQDTDSCL VYGGQQMILT GQNFTSESKV VFTEKTTDGQ QIWEMEATVD KDKSQPNMLF 
VEIPEYRNKH IRTPVKVNFY VINGKRKRSQ PQHFTYHPVP AIKTEPTDEY DPTLICSPTH 
GGLGSQPYYP QHPMVAESPS CLVATMAPCQ QFRTGLSSPD ARYQQQNPAA VLYQRSKSLS 
PSLLGYQQPA LMAAPLSLAD AHRSVLVHAG SQGQSSALLH PSPTNQQASP VIHYSPTNQQ 
LRCGSHQEFQ HIMYCENFAP GTTRPGPPPV SQGQRLSPGS YPTVIQQQNA TSQRAAKNGP 
PVSDQKEVLP AGVTIKQEQN LDQTYLDDVN EIIRKEFSGP PARNQT

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.