Details for: NFIL3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 179.1119
Cell Significance Index: -27.8600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 108.1242
Cell Significance Index: -27.4300 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 59.2482
Cell Significance Index: -24.0700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 42.3086
Cell Significance Index: -28.3900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 22.6042
Cell Significance Index: -27.8700 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 10.2992
Cell Significance Index: -27.5900 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 7.0539
Cell Significance Index: -27.8400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 4.0882
Cell Significance Index: 117.1900 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 3.2487
Cell Significance Index: -7.1100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.5286
Cell Significance Index: 25.7500 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 1.1689
Cell Significance Index: 9.0100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 1.1245
Cell Significance Index: 79.5300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.9701
Cell Significance Index: 428.9200 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.9279
Cell Significance Index: 22.6400 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.9171
Cell Significance Index: 47.6400 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.7716
Cell Significance Index: 105.9600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.7055
Cell Significance Index: 637.0200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.6662
Cell Significance Index: 9.0900 - Cell Name: perivascular cell (CL4033054)
Fold Change: 0.6432
Cell Significance Index: 2.9700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5407
Cell Significance Index: 32.4600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.5054
Cell Significance Index: 54.9700 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.4593
Cell Significance Index: 74.7000 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: 0.4156
Cell Significance Index: 7.3500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4132
Cell Significance Index: 18.7300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4056
Cell Significance Index: 80.5000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.3857
Cell Significance Index: 10.3000 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.3653
Cell Significance Index: 2.2700 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3608
Cell Significance Index: 23.2800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.3016
Cell Significance Index: 16.9300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.2608
Cell Significance Index: 142.4300 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.2325
Cell Significance Index: 2.4700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2253
Cell Significance Index: 4.8800 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.2112
Cell Significance Index: 134.1300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2032
Cell Significance Index: 24.9800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1926
Cell Significance Index: 9.0500 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1844
Cell Significance Index: 5.0200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1834
Cell Significance Index: 5.2900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1803
Cell Significance Index: 17.8400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1679
Cell Significance Index: 33.6800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1498
Cell Significance Index: 28.5000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1458
Cell Significance Index: 11.1900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 0.1426
Cell Significance Index: 2.6400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1259
Cell Significance Index: 22.7000 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.1240
Cell Significance Index: 3.1000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.1175
Cell Significance Index: 8.7600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0663
Cell Significance Index: 3.0900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0649
Cell Significance Index: 122.2300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0621
Cell Significance Index: 22.2900 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 0.0481
Cell Significance Index: 5.5100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0336
Cell Significance Index: 1.1800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.0241
Cell Significance Index: 4.1100 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.0228
Cell Significance Index: 2.6000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0225
Cell Significance Index: 1.3800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0189
Cell Significance Index: 13.0800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0118
Cell Significance Index: 0.8100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0118
Cell Significance Index: 1.5100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0071
Cell Significance Index: 10.8900 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0049
Cell Significance Index: 0.6300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0007
Cell Significance Index: 1.2200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0052
Cell Significance Index: -7.1000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0081
Cell Significance Index: -6.0200 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0102
Cell Significance Index: -7.5000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0123
Cell Significance Index: -7.6900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0156
Cell Significance Index: -7.0600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0219
Cell Significance Index: -16.6000 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0317
Cell Significance Index: -17.8600 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0370
Cell Significance Index: -0.8100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0399
Cell Significance Index: -4.0800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0609
Cell Significance Index: -17.5100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0674
Cell Significance Index: -14.2000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0684
Cell Significance Index: -9.9500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0803
Cell Significance Index: -9.3600 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0833
Cell Significance Index: -1.2300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0858
Cell Significance Index: -2.3000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1011
Cell Significance Index: -5.3100 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: -0.1073
Cell Significance Index: -1.1200 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.1611
Cell Significance Index: -2.6000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1841
Cell Significance Index: -3.8200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1882
Cell Significance Index: -22.2000 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.1986
Cell Significance Index: -5.5500 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2081
Cell Significance Index: -13.9900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.2139
Cell Significance Index: -2.4300 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2206
Cell Significance Index: -4.3100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.2391
Cell Significance Index: -15.0700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2471
Cell Significance Index: -25.7300 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2598
Cell Significance Index: -8.3200 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.2667
Cell Significance Index: -13.4800 - Cell Name: peg cell (CL4033014)
Fold Change: -0.2805
Cell Significance Index: -6.4800 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2852
Cell Significance Index: -22.5900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2955
Cell Significance Index: -7.7700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3185
Cell Significance Index: -16.5900 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.3303
Cell Significance Index: -8.4900 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.3494
Cell Significance Index: -2.1500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3608
Cell Significance Index: -22.1200 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3710
Cell Significance Index: -9.9300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.4268
Cell Significance Index: -9.0900 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.4348
Cell Significance Index: -6.1900 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.4738
Cell Significance Index: -3.2100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.4964
Cell Significance Index: -10.3900 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.5118
Cell Significance Index: -20.9700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 652527499
Symbol: NFIL3_HUMAN
Name: Nuclear factor interleukin-3-regulated protein
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 1620116
Title: Transcriptional repression by a novel member of the bZIP family of transcription factors.
PubMed ID: 1620116
PubMed ID: 7565758
Title: Molecular cloning and characterization of NF-IL3A, a transcriptional activator of the human interleukin-3 promoter.
PubMed ID: 7565758
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8836190
Title: Protein-protein interaction between the transcriptional repressor E4BP4 and the TBP-binding protein Dr1.
PubMed ID: 8836190
PubMed ID: 10942106
Title: Exclusion of NFIL3 as the gene causing hereditary sensory neuropathy type I by mutation analysis.
PubMed ID: 10942106
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24062447
Title: Epigenetic control of natural killer cell maturation by histone H2A deubiquitinase, MYSM1.
PubMed ID: 24062447
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25114211
Title: Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.
PubMed ID: 25114211
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
Sequence Information:
- Length: 462
- Mass: 51472
- Checksum: D19946AAC774C3E7
- Sequence:
MQLRKMQTVK KEQASLDASS NVDKMMVLNS ALTEVSEDST TGEELLLSEG SVGKNKSSAC RRKREFIPDE KKDAMYWEKR RKNNEAAKRS REKRRLNDLV LENKLIALGE ENATLKAELL SLKLKFGLIS STAYAQEIQK LSNSTAVYFQ DYQTSKSNVS SFVDEHEPSM VSSSCISVIK HSPQSSLSDV SEVSSVEHTQ ESSVQGSCRS PENKFQIIKQ EPMELESYTR EPRDDRGSYT ASIYQNYMGN SFSGYSHSPP LLQVNRSSSN SPRTSETDDG VVGKSSDGED EQQVPKGPIH SPVELKHVHA TVVKVPEVNS SALPHKLRIK AKAMQIKVEA FDNEFEATQK LSSPIDMTSK RHFELEKHSA PSMVHSSLTP FSVQVTNIQD WSLKSEHWHQ KELSGKTQNS FKTGVVEMKD SGYKVSDPEN LYLKQGIANL SAEVVSLKRL IATQPISASD SG
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.