Details for: OAS3

Gene ID: 4940

Symbol: OAS3

Ensembl ID: ENSG00000111331

Description: 2'-5'-oligoadenylate synthetase 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 67.8902
    Cell Significance Index: -10.5600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 37.4542
    Cell Significance Index: -9.5000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 24.1719
    Cell Significance Index: -9.8200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 21.3264
    Cell Significance Index: -10.9700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 10.3274
    Cell Significance Index: -9.8600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.6783
    Cell Significance Index: -10.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.8822
    Cell Significance Index: -10.4000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.7141
    Cell Significance Index: -10.7100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 2.0447
    Cell Significance Index: 106.2200
  • Cell Name: oral mucosa squamous cell (CL1001576)
    Fold Change: 1.7084
    Cell Significance Index: 14.6800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 1.4589
    Cell Significance Index: 75.9900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.0484
    Cell Significance Index: 16.2200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.9763
    Cell Significance Index: 13.3200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.8050
    Cell Significance Index: 93.8100
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.7753
    Cell Significance Index: 14.3300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5777
    Cell Significance Index: 34.6800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5730
    Cell Significance Index: 517.3400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5438
    Cell Significance Index: 59.1500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5333
    Cell Significance Index: 52.7600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4740
    Cell Significance Index: 77.1000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.3995
    Cell Significance Index: 6.0200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3491
    Cell Significance Index: 62.9400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.3346
    Cell Significance Index: 9.3500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3083
    Cell Significance Index: 6.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2659
    Cell Significance Index: 18.3900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2496
    Cell Significance Index: 30.7000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2137
    Cell Significance Index: 40.6600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2108
    Cell Significance Index: 27.0200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1911
    Cell Significance Index: 5.1200
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.1815
    Cell Significance Index: 1.4800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0893
    Cell Significance Index: 12.2600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.0860
    Cell Significance Index: 1.5200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0847
    Cell Significance Index: 16.8100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0714
    Cell Significance Index: 2.5100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0708
    Cell Significance Index: 2.0400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0512
    Cell Significance Index: 1.2800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0431
    Cell Significance Index: 19.0600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.0199
    Cell Significance Index: 0.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0194
    Cell Significance Index: 10.5800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0174
    Cell Significance Index: 0.3700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0110
    Cell Significance Index: 0.5000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0069
    Cell Significance Index: 0.4500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0048
    Cell Significance Index: -9.0100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0078
    Cell Significance Index: -14.4600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0083
    Cell Significance Index: -5.7600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0092
    Cell Significance Index: -14.1700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0101
    Cell Significance Index: -7.6600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0111
    Cell Significance Index: -15.0300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0117
    Cell Significance Index: -1.2000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0140
    Cell Significance Index: -10.2400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0151
    Cell Significance Index: -9.6100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0156
    Cell Significance Index: -5.5900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0172
    Cell Significance Index: -12.7400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0204
    Cell Significance Index: -0.9500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0218
    Cell Significance Index: -12.2900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0246
    Cell Significance Index: -0.2800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0247
    Cell Significance Index: -4.9500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0255
    Cell Significance Index: -0.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0256
    Cell Significance Index: -11.6200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0323
    Cell Significance Index: -9.3100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0323
    Cell Significance Index: -1.6300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0386
    Cell Significance Index: -0.5500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0404
    Cell Significance Index: -4.6300
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0430
    Cell Significance Index: -0.2600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0449
    Cell Significance Index: -1.1800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0456
    Cell Significance Index: -2.0200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0536
    Cell Significance Index: -1.4600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0577
    Cell Significance Index: -7.4500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0595
    Cell Significance Index: -10.1600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0614
    Cell Significance Index: -12.9400
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0644
    Cell Significance Index: -0.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0660
    Cell Significance Index: -7.7800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0670
    Cell Significance Index: -9.7400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0747
    Cell Significance Index: -5.2800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0864
    Cell Significance Index: -3.2700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0921
    Cell Significance Index: -2.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0940
    Cell Significance Index: -3.0100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1001
    Cell Significance Index: -7.4600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1026
    Cell Significance Index: -10.6800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1128
    Cell Significance Index: -5.3000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1303
    Cell Significance Index: -1.2000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1327
    Cell Significance Index: -3.3900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1402
    Cell Significance Index: -3.7500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1441
    Cell Significance Index: -9.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1504
    Cell Significance Index: -11.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1577
    Cell Significance Index: -10.6100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1652
    Cell Significance Index: -2.7700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1669
    Cell Significance Index: -4.2900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1703
    Cell Significance Index: -10.4700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1714
    Cell Significance Index: -10.5100
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.1771
    Cell Significance Index: -2.6900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1796
    Cell Significance Index: -7.3600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1838
    Cell Significance Index: -10.3200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1843
    Cell Significance Index: -2.6500
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.2012
    Cell Significance Index: -1.2500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2182
    Cell Significance Index: -4.6700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2301
    Cell Significance Index: -12.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2676
    Cell Significance Index: -8.7600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2681
    Cell Significance Index: -9.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2714
    Cell Significance Index: -9.4300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** OAS3 is a member of the 2'-5'-oligoadenylate synthetase family, which consists of three isoforms: OAS1, OAS2, and OAS3. OAS3 is the largest isoform and is responsible for the production of 2'-5'-oligoadenylates. The gene is highly conserved across species, suggesting its importance in the innate immune response. OAS3 is a cytoplasmic enzyme that requires a metal ion cofactor for its activity. It is also a negative regulator of chemokine production, which is essential for the prevention of excessive inflammation during viral infections. **Pathways and Functions** OAS3 is involved in several pathways that are crucial for the antiviral defense: 1. **Interferon signaling pathway**: OAS3 is a key component of the interferon signaling pathway, which is activated in response to viral infections. It produces 2'-5'-oligoadenylates, which activate PKR and induce the expression of ISGs. 2. **Antiviral response**: OAS3 is essential for the antiviral response, as it produces 2'-5'-oligoadenylates that inhibit viral replication. 3. **Cytokine signaling**: OAS3 is also involved in cytokine signaling, particularly in the production of interferon-alpha (IFN-α) and interferon-beta (IFN-β). 4. **Immune system**: OAS3 is highly expressed in immune cells, including macrophages and dendritic cells, where it plays a critical role in the regulation of immune responses. **Clinical Significance** OAS3 has significant clinical implications, particularly in the treatment of viral infections: 1. **Viral infections**: OAS3 is essential for the antiviral defense against viral infections, such as influenza, herpes simplex virus, and HIV. 2. **Antiviral therapy**: OAS3 inhibitors, such as ribavirin, have been used to treat viral infections, including hepatitis C and respiratory syncytial virus (RSV) infections. 3. **Cancer therapy**: OAS3 has been shown to have antitumor activity, and its inhibitors are being explored as potential cancer therapies. 4. **Autoimmune diseases**: OAS3 is also involved in the regulation of immune responses in autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. In conclusion, OAS3 is a crucial gene involved in the innate immune response, specifically in the antiviral defense mechanism. Its dysregulation has significant clinical implications, particularly in the treatment of viral infections and autoimmune diseases. Further research is needed to fully understand the mechanisms of OAS3 and its role in human disease.

Genular Protein ID: 4057756274

Symbol: OAS3_HUMAN

Name: 2'-5'-oligoadenylate synthase 3

UniProtKB Accession Codes:

Q9Y6K5 Q2HJ14 Q9H3P5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 11 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 28 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 1 Rhea 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9880533

Title: The 100-kDa 2',5'-oligoadenylate synthetase catalyzing preferentially the synthesis of dimeric pppA2'p5'A molecules is composed of three homologous domains.

PubMed ID: 9880533

DOI: 10.1074/jbc.274.3.1557

PubMed ID: 11280764

Title: Molecular basis of T cell-mediated recognition of pancreatic cancer cells.

PubMed ID: 11280764

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11112351

Title: Characterization of the gene encoding the 100-kDa form of human 2', 5'oligoadenylate synthetase.

PubMed ID: 11112351

DOI: 10.1006/geno.2000.6382

PubMed ID: 17408844

Title: The human 2'-5'oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation.

PubMed ID: 17408844

DOI: 10.1016/j.biochi.2007.02.003

PubMed ID: 19923450

Title: Distinct antiviral roles for human 2',5'-oligoadenylate synthetase family members against dengue virus infection.

PubMed ID: 19923450

DOI: 10.4049/jimmunol.0902728

PubMed ID: 19904482

Title: Evolution of the 2'-5'-oligoadenylate synthetase family in eukaryotes and bacteria.

PubMed ID: 19904482

DOI: 10.1007/s00239-009-9299-1

PubMed ID: 19056102

Title: The large form of human 2',5'-Oligoadenylate Synthetase (OAS3) exerts antiviral effect against Chikungunya virus.

PubMed ID: 19056102

DOI: 10.1016/j.virol.2008.10.021

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21142819

Title: The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities.

PubMed ID: 21142819

DOI: 10.1089/jir.2010.0107

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 25775560

Title: Structural mechanism of sensing long dsRNA via a noncatalytic domain in human oligoadenylate synthetase 3.

PubMed ID: 25775560

DOI: 10.1073/pnas.1419409112

Sequence Information:

  • Length: 1087
  • Mass: 121170
  • Checksum: 36DAADE4574DE961
  • Sequence:
    • MDLYSTPAAA LDRFVARRLQ PRKEFVEKAR RALGALAAAL RERGGRLGAA APRVLKTVKG 
GSSGRGTALK GGCDSELVIF LDCFKSYVDQ RARRAEILSE MRASLESWWQ NPVPGLRLTF 
PEQSVPGALQ FRLTSVDLED WMDVSLVPAF NVLGQAGSGV KPKPQVYSTL LNSGCQGGEH 
AACFTELRRN FVNIRPAKLK NLILLVKHWY HQVCLQGLWK ETLPPVYALE LLTIFAWEQG 
CKKDAFSLAE GLRTVLGLIQ QHQHLCVFWT VNYGFEDPAV GQFLQRQLKR PRPVILDPAD 
PTWDLGNGAA WHWDLLAQEA ASCYDHPCFL RGMGDPVQSW KGPGLPRAGC SGLGHPIQLD 
PNQKTPENSK SLNAVYPRAG SKPPSCPAPG PTGAASIVPS VPGMALDLSQ IPTKELDRFI 
QDHLKPSPQF QEQVKKAIDI ILRCLHENCV HKASRVSKGG SFGRGTDLRD GCDVELIIFL 
NCFTDYKDQG PRRAEILDEM RAQLESWWQD QVPSLSLQFP EQNVPEALQF QLVSTALKSW 
TDVSLLPAFD AVGQLSSGTK PNPQVYSRLL TSGCQEGEHK ACFAELRRNF MNIRPVKLKN 
LILLVKHWYR QVAAQNKGKG PAPASLPPAY ALELLTIFAW EQGCRQDCFN MAQGFRTVLG 
LVQQHQQLCV YWTVNYSTED PAMRMHLLGQ LRKPRPLVLD PADPTWNVGH GSWELLAQEA 
AALGMQACFL SRDGTSVQPW DVMPALLYQT PAGDLDKFIS EFLQPNRQFL AQVNKAVDTI 
CSFLKENCFR NSPIKVIKVV KGGSSAKGTA LRGRSDADLV VFLSCFSQFT EQGNKRAEII 
SEIRAQLEAC QQERQFEVKF EVSKWENPRV LSFSLTSQTM LDQSVDFDVL PAFDALGQLV 
SGSRPSSQVY VDLIHSYSNA GEYSTCFTEL QRDFIISRPT KLKSLIRLVK HWYQQCTKIS 
KGRGSLPPQH GLELLTVYAW EQGGKDSQFN MAEGFRTVLE LVTQYRQLCI YWTINYNAKD 
KTVGDFLKQQ LQKPRPIILD PADPTGNLGH NARWDLLAKE AAACTSALCC MGRNGIPIQP 
WPVKAAV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.