Details for: OPRL1

Gene ID: 4987

Symbol: OPRL1

Ensembl ID: ENSG00000125510

Description: opioid related nociceptin receptor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 10.1323
    Cell Significance Index: -2.5700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 2.7756
    Cell Significance Index: -2.6500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 2.4981
    Cell Significance Index: -3.0800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7001
    Cell Significance Index: 15.3300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.3290
    Cell Significance Index: -0.7200
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.2779
    Cell Significance Index: 3.9000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.2669
    Cell Significance Index: 3.5600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2606
    Cell Significance Index: 6.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2324
    Cell Significance Index: 46.6200
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1169
    Cell Significance Index: 1.4500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0985
    Cell Significance Index: 68.1400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0761
    Cell Significance Index: 2.8800
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: 0.0731
    Cell Significance Index: 0.9800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0661
    Cell Significance Index: 3.4700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0629
    Cell Significance Index: 22.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0579
    Cell Significance Index: 2.5600
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: 0.0420
    Cell Significance Index: 0.4600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: 0.0390
    Cell Significance Index: 0.4300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0265
    Cell Significance Index: 1.7100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0237
    Cell Significance Index: 1.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0086
    Cell Significance Index: 0.2300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0043
    Cell Significance Index: 0.1100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0043
    Cell Significance Index: 0.8500
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.0040
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0003
    Cell Significance Index: 0.5200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0009
    Cell Significance Index: -0.0400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0013
    Cell Significance Index: -2.3800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0016
    Cell Significance Index: -0.1900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0016
    Cell Significance Index: -2.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0023
    Cell Significance Index: -3.1700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0025
    Cell Significance Index: -0.3500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0036
    Cell Significance Index: -0.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0038
    Cell Significance Index: -2.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0041
    Cell Significance Index: -2.9800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0043
    Cell Significance Index: -3.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0044
    Cell Significance Index: -3.3000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0048
    Cell Significance Index: -2.6300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0053
    Cell Significance Index: -2.9700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0057
    Cell Significance Index: -1.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0066
    Cell Significance Index: -3.0000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0076
    Cell Significance Index: -2.1800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0082
    Cell Significance Index: -1.0500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0095
    Cell Significance Index: -0.1900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0110
    Cell Significance Index: -1.1200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0133
    Cell Significance Index: -1.9400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0137
    Cell Significance Index: -2.3400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0142
    Cell Significance Index: -0.7200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0150
    Cell Significance Index: -0.4900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0152
    Cell Significance Index: -1.7700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0159
    Cell Significance Index: -3.3500
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0168
    Cell Significance Index: -0.3100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0185
    Cell Significance Index: -0.5900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0202
    Cell Significance Index: -2.4800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0216
    Cell Significance Index: -2.4800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0222
    Cell Significance Index: -2.8700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0247
    Cell Significance Index: -0.6900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0290
    Cell Significance Index: -3.0200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0304
    Cell Significance Index: -1.2500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0321
    Cell Significance Index: -1.6700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0326
    Cell Significance Index: -0.7100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0326
    Cell Significance Index: -2.4300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0327
    Cell Significance Index: -0.8400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0330
    Cell Significance Index: -2.5300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0353
    Cell Significance Index: -0.9600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0354
    Cell Significance Index: -0.7000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0368
    Cell Significance Index: -1.2900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0373
    Cell Significance Index: -2.6400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0413
    Cell Significance Index: -1.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0424
    Cell Significance Index: -1.9200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0451
    Cell Significance Index: -2.5300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0481
    Cell Significance Index: -1.2000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0496
    Cell Significance Index: -0.8500
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0512
    Cell Significance Index: -0.6700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0565
    Cell Significance Index: -0.9500
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0638
    Cell Significance Index: -0.6100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0687
    Cell Significance Index: -0.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0734
    Cell Significance Index: -2.5800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0745
    Cell Significance Index: -1.9600
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0767
    Cell Significance Index: -1.0600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0772
    Cell Significance Index: -1.5700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0789
    Cell Significance Index: -0.8600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0794
    Cell Significance Index: -2.7600
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0805
    Cell Significance Index: -1.0200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0810
    Cell Significance Index: -1.7200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0812
    Cell Significance Index: -2.9800
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0813
    Cell Significance Index: -1.1800
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0828
    Cell Significance Index: -1.6300
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0879
    Cell Significance Index: -1.5200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0898
    Cell Significance Index: -2.2400
  • Cell Name: granule cell (CL0000120)
    Fold Change: -0.0905
    Cell Significance Index: -1.0300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0926
    Cell Significance Index: -1.9800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0930
    Cell Significance Index: -2.7400
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0935
    Cell Significance Index: -1.5400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0951
    Cell Significance Index: -2.7400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0964
    Cell Significance Index: -2.8300
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0967
    Cell Significance Index: -1.8900
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0972
    Cell Significance Index: -1.5600
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0987
    Cell Significance Index: -1.1800
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1008
    Cell Significance Index: -2.1100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The NOP receptor exhibits several key characteristics that distinguish it from other G protein-coupled receptors. These include: * **High affinity for nociceptin/orphanin FQ**: The NOP receptor has a high affinity for its endogenous ligand, nociceptin/orphanin FQ, which modulates its activity. * **Inverse agonist activity**: The NOP receptor can act as an inverse agonist for other opioid receptors, such as the mu and delta receptors, which can lead to the activation of these receptors and the subsequent modulation of pain and other physiological responses. * **Modulation of adenylate cyclase activity**: The NOP receptor inhibits adenylate cyclase activity, which can lead to the suppression of cAMP production and the subsequent modulation of downstream signaling pathways. * **Regulation of pain perception**: The NOP receptor plays a critical role in the regulation of pain perception, particularly in the context of chronic pain and cancer. **Pathways and Functions** The NOP receptor is involved in several signaling pathways, including: * **Adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway**: The NOP receptor inhibits adenylate cyclase activity, which can lead to the suppression of cAMP production and the subsequent modulation of downstream signaling pathways. * **Calcium-mediated signaling**: The NOP receptor can activate calcium channels and modulate calcium-mediated signaling pathways, which can lead to the activation of various cellular responses. * **Neuropeptide signaling pathway**: The NOP receptor is involved in the regulation of neuropeptide signaling pathways, which can lead to the modulation of pain, mood, and other physiological responses. * **G protein-coupled opioid receptor signaling pathway**: The NOP receptor can modulate the activity of other opioid receptors, such as the mu and delta receptors, which can lead to the activation of these receptors and the subsequent modulation of pain and other physiological responses. **Clinical Significance** The NOP receptor has been implicated in several diseases, including: * **Chronic pain**: The NOP receptor plays a critical role in the regulation of pain perception, particularly in the context of chronic pain. * **Cancer**: The NOP receptor is overexpressed in various types of cancer, including breast, lung, and colon cancer, and its dysfunction has been implicated in the development of cancer. * **Addiction**: The NOP receptor is involved in the regulation of reward and addiction behaviors, and its dysfunction has been implicated in the development of addiction. * **Mood disorders**: The NOP receptor is involved in the regulation of mood and emotional responses, and its dysfunction has been implicated in the development of mood disorders, such as depression and anxiety. In conclusion, the OPRL1 gene encodes for the opioid-related nociceptin receptor 1 (NOP), a G protein-coupled receptor that plays a crucial role in the regulation of various physiological and pathological processes. The NOP receptor is widely expressed in various tissues, including the brain, gut, and kidneys, and its dysfunction has been implicated in several diseases, including pain, addiction, and cancer. Further research is needed to fully understand the mechanisms of the NOP receptor and its role in human disease.

Genular Protein ID: 1103394130

Symbol: OPRX_HUMAN

Name: Nociceptin receptor

UniProtKB Accession Codes:

P41146 Q8TD34 Q8WYH9 Q9H4K4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 DrugCentral 1 EMBL 10 EMDB 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 21 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 2 RefSeq 8 SIGNOR 1 SMART 1 SMR 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8137918

Title: ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization.

PubMed ID: 8137918

DOI: 10.1016/0014-5793(94)80235-1

PubMed ID: 11238602

Title: Nociceptin stimulates neutrophil chemotaxis and recruitment: Inhibition by aspirin-triggered-15-Epi-lipoxin A4.

PubMed ID: 11238602

DOI: 10.4049/jimmunol.166.6.3650

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7500847

Title: Expression of alternate forms of brain opioid 'orphan' receptor mRNA in activated human peripheral blood lymphocytes and lymphocytic cell lines.

PubMed ID: 7500847

DOI: 10.1016/0169-328x(95)00096-b

PubMed ID: 12568343

Title: Agonist-induced internalization and desensitization of the human nociceptin receptor expressed in CHO cells.

PubMed ID: 12568343

DOI: 10.1007/s000180200016

PubMed ID: 23086955

Title: Serine 363 is required for nociceptin/orphanin FQ opioid receptor (NOPR) desensitization, internalization, and arrestin signaling.

PubMed ID: 23086955

DOI: 10.1074/jbc.m112.405696

PubMed ID: 22596163

Title: Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic.

PubMed ID: 22596163

DOI: 10.1038/nature11085

Sequence Information:

  • Length: 370
  • Mass: 40693
  • Checksum: 613700C0B4D093BA
  • Sequence:
    • MEPLFPAPFW EVIYGSHLQG NLSLLSPNHS LLPPHLLLNA SHGAFLPLGL KVTIVGLYLA 
VCVGGLLGNC LVMYVILRHT KMKTATNIYI FNLALADTLV LLTLPFQGTD ILLGFWPFGN 
ALCKTVIAID YYNMFTSTFT LTAMSVDRYV AICHPIRALD VRTSSKAQAV NVAIWALASV 
VGVPVAIMGS AQVEDEEIEC LVEIPTPQDY WGPVFAICIF LFSFIVPVLV ISVCYSLMIR 
RLRGVRLLSG SREKDRNLRR ITRLVLVVVA VFVGCWTPVQ VFVLAQGLGV QPSSETAVAI 
LRFCTALGYV NSCLNPILYA FLDENFKACF RKFCCASALR RDVQVSDRVR SIAKDVALAC 
KTSETVPRPA

Genular Protein ID: 3622843563

Symbol: Q8IXB0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8IXB0

Database IDs:

ARBA 17 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 Pfam 1 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 341
  • Mass: 37255
  • Checksum: A614F13BD595C2F1
  • Sequence:
    • MPATAPSCPS GSRSPSWGST WPCVSEGSWG TALSCTSSSG RLGPKVPVWH TKMKTATNIY 
IFNLALADTL VLLTLPFQGT DILLGFWPFG NALCKTVIAI DYYNMFTSTF TLTAMSVDRY 
VAICHPIRAL DVRTSSKAQA VNVAIWALAS VVGVPVAIMG SAQVEDEEIE CLVEIPTPQD 
YWGPVFAICI FLFSFIVPVL VISVCYSLMI RRLRGVRLLS GSREKDRNLR RITRLVLVVV 
AVFVGCWTPV QVFVLAQGLG VQPSSETAVA ILRFCTALGY VNSCLNPILY AFLDENFKAC 
FRKFCCASAL RRDVQVSDRV RSIAKDVALA CKTSETVPRP A

Genular Protein ID: 1159252529

Symbol: A0A5F9ZI64_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A5F9ZI64

Database IDs:

ARBA 17 Antibodypedia 1 Bgee 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 3 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 399
  • Mass: 43679
  • Checksum: D22F6FC046D8833D
  • Sequence:
    • MEPLFPAPFW EVIYGSHLQG NLSLLSPNHS LLPPHLLLNA SHGAFLPLGL KVTIVGLYLA 
VCVGGLLGNC LVMYVILRHT KMKTATNIYI FNLALADTLV LLTLPFQGTD ILLGFWPFGN 
ALCKTVIAID YYNMFTSTFT LTAMSVDRYV AICHPIRALD VRTSSKAQAV NVAIWALASV 
VGVPVAIMGS AQVEDEEIEC LVEIPTPQDY WGPVFAICIF LFSFIVPVLV ISVCYSLMIR 
RLRGVRLLSG SREKDRNLRR ITRLVLVVVA VFVGCWTPVQ VFVLAQGLGV QPSSETAVAI 
LRFCTALGYV NSCLNPILYA FLDENFKACF RKFCCASALR RDVQVSDRVR SIAKDVALAC 
KTSETVPRPA XLGVDLPMVP VSPQSPSTPN TELTQVTAL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.