Details for: GEMIN4

Gene ID: 50628

Symbol: GEMIN4

Ensembl ID: ENSG00000179409

Description: gem nuclear organelle associated protein 4

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 46.6102
    Cell Significance Index: -7.2500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 25.0943
    Cell Significance Index: -6.3700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 18.0428
    Cell Significance Index: -7.3300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 17.8132
    Cell Significance Index: -8.4100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 6.2452
    Cell Significance Index: -7.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.0610
    Cell Significance Index: -8.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 1.9843
    Cell Significance Index: -7.8300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 1.8232
    Cell Significance Index: -5.6000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.5239
    Cell Significance Index: 290.0000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.1181
    Cell Significance Index: 110.6100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9193
    Cell Significance Index: 55.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.8318
    Cell Significance Index: 22.6400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7778
    Cell Significance Index: 84.6100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7322
    Cell Significance Index: 9.9900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.6550
    Cell Significance Index: 591.4100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6077
    Cell Significance Index: 98.8400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4057
    Cell Significance Index: 47.2800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3747
    Cell Significance Index: 25.9200
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.3424
    Cell Significance Index: 5.2000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.3392
    Cell Significance Index: 17.6200
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.3057
    Cell Significance Index: 4.9100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2997
    Cell Significance Index: 8.6400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.2952
    Cell Significance Index: 7.9100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.2948
    Cell Significance Index: 7.5300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2494
    Cell Significance Index: 172.5100
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 0.2307
    Cell Significance Index: 0.5200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2159
    Cell Significance Index: 6.0400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2150
    Cell Significance Index: 5.7500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1828
    Cell Significance Index: 3.9600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1422
    Cell Significance Index: 17.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1417
    Cell Significance Index: 62.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1246
    Cell Significance Index: 24.7300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1225
    Cell Significance Index: 22.0800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1201
    Cell Significance Index: 65.5800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1127
    Cell Significance Index: 5.1100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0997
    Cell Significance Index: 7.0500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0967
    Cell Significance Index: 0.6600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0939
    Cell Significance Index: 4.3800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0862
    Cell Significance Index: 10.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0829
    Cell Significance Index: 10.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0752
    Cell Significance Index: 10.3300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0607
    Cell Significance Index: 1.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0602
    Cell Significance Index: 12.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0524
    Cell Significance Index: 1.3100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.0490
    Cell Significance Index: 0.8200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.0448
    Cell Significance Index: 0.7100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0413
    Cell Significance Index: 3.0800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0381
    Cell Significance Index: 13.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0353
    Cell Significance Index: 1.1300
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0325
    Cell Significance Index: 4.1600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0248
    Cell Significance Index: 0.8700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0244
    Cell Significance Index: 0.5200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0209
    Cell Significance Index: 1.3500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0164
    Cell Significance Index: 0.5700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0121
    Cell Significance Index: 0.6300
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.0073
    Cell Significance Index: 0.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0017
    Cell Significance Index: 3.2500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0004
    Cell Significance Index: -0.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0016
    Cell Significance Index: -0.2800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0037
    Cell Significance Index: -5.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0039
    Cell Significance Index: -7.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0057
    Cell Significance Index: -7.7400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0058
    Cell Significance Index: -4.4000
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0062
    Cell Significance Index: -4.5600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0066
    Cell Significance Index: -4.2000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0082
    Cell Significance Index: -0.2200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0115
    Cell Significance Index: -8.5100
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0133
    Cell Significance Index: -0.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0142
    Cell Significance Index: -7.9800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0153
    Cell Significance Index: -9.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0168
    Cell Significance Index: -7.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0180
    Cell Significance Index: -2.6200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0182
    Cell Significance Index: -5.2400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0281
    Cell Significance Index: -0.7400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0300
    Cell Significance Index: -3.0600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0385
    Cell Significance Index: -2.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0422
    Cell Significance Index: -2.6600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0437
    Cell Significance Index: -2.4500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0454
    Cell Significance Index: -9.5600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0455
    Cell Significance Index: -1.3400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0459
    Cell Significance Index: -2.8200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0476
    Cell Significance Index: -5.4500
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0485
    Cell Significance Index: -1.3900
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0502
    Cell Significance Index: -0.5200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0633
    Cell Significance Index: -4.8600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0685
    Cell Significance Index: -3.4600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0727
    Cell Significance Index: -7.5700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0827
    Cell Significance Index: -1.7300
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0871
    Cell Significance Index: -0.7400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0921
    Cell Significance Index: -7.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0966
    Cell Significance Index: -5.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1048
    Cell Significance Index: -7.0500
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1196
    Cell Significance Index: -1.3000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1213
    Cell Significance Index: -2.6600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1229
    Cell Significance Index: -1.7600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1307
    Cell Significance Index: -1.9700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1373
    Cell Significance Index: -2.9400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1403
    Cell Significance Index: -2.0100
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.1405
    Cell Significance Index: -1.9700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1428
    Cell Significance Index: -3.3000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** GEMIN4 is a nuclear protein that associates with geminates, a type of nuclear organelle involved in RNA metabolism and replication. It has been shown to interact with various proteins, including snRNP components, and plays a crucial role in regulating RNA processing and translation. GEMIN4 is highly expressed in hematopoietic cells, immune cells, and epithelial cells, suggesting its involvement in immune regulation and cellular homeostasis. **Pathways and Functions:** GEMIN4's involvement in RNA metabolism and protein binding pathways is well established. It has been shown to interact with snRNP components, regulating RNA processing and translation. Additionally, GEMIN4 has been implicated in modulating host translation machinery in response to viral infections. Its interaction with SARS-CoV-2 genome has been identified, suggesting a potential role in regulating viral replication and immune evasion. Furthermore, GEMIN4's expression in immune cells and epithelial cells suggests its involvement in immune regulation and cellular homeostasis. **Clinical Significance:** The study of GEMIN4 has significant implications for our understanding of viral infections and immune regulation. Its interaction with SARS-CoV-2 genome highlights the potential for GEMIN4 to serve as a therapeutic target or biomarker for COVID-19. Additionally, GEMIN4's involvement in immune regulation and cellular homeostasis suggests its potential role in the development of immunotherapies for various diseases. Further research is needed to fully elucidate the functional significance of GEMIN4 in human health and disease. **Conclusion:** GEMIN4 is a multifunctional protein that plays a crucial role in RNA metabolism, protein binding, and immune regulation. Its interaction with SARS-CoV-2 genome highlights its potential as a therapeutic target or biomarker for COVID-19. Further research is needed to fully elucidate the functional significance of GEMIN4 in human health and disease, and to explore its potential applications in immunotherapy and disease diagnosis.

Genular Protein ID: 3658030938

Symbol: GEMI4_HUMAN

Name: Gem-associated protein 4

UniProtKB Accession Codes:

P57678 Q9NZS7 Q9UG32 Q9Y4Q2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 15 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 1 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10725331

Title: Gemin4: a novel component of the SMN complex that is found in both gems and nucleoli.

PubMed ID: 10725331

DOI: 10.1083/jcb.148.6.1177

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 12668731

Title: Protein phosphatase 4 interacts with the survival of motor neurons complex and enhances the temporal localisation of snRNPs.

PubMed ID: 12668731

DOI: 10.1242/jcs.00409

PubMed ID: 16314521

Title: Specific sequence features, recognized by the SMN complex, identify snRNAs and determine their fate as snRNPs.

PubMed ID: 16314521

DOI: 10.1128/mcb.25.24.10989-11004.2005

PubMed ID: 17178713

Title: A comprehensive interaction map of the human survival of motor neuron (SMN) complex.

PubMed ID: 17178713

DOI: 10.1074/jbc.m608528200

PubMed ID: 18984161

Title: An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs.

PubMed ID: 18984161

DOI: 10.1016/j.cell.2008.09.020

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 33963192

Title: Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder.

PubMed ID: 33963192

DOI: 10.1038/s41467-021-22627-w

PubMed ID: 25558065

Title: Accelerating novel candidate gene discovery in neurogenetic disorders via whole-exome sequencing of prescreened multiplex consanguineous families.

PubMed ID: 25558065

DOI: 10.1016/j.celrep.2014.12.015

PubMed ID: 30237576

Title: Autozygome and high throughput confirmation of disease genes candidacy.

PubMed ID: 30237576

DOI: 10.1038/s41436-018-0138-x

PubMed ID: 35861185

Title: Further delineation of GEMIN4 related neurodevelopmental disorder with microcephaly, cataract, and renal abnormalities syndrome.

PubMed ID: 35861185

DOI: 10.1002/ajmg.a.62894

Sequence Information:

  • Length: 1058
  • Mass: 120037
  • Checksum: ACEC60EC19EF5081
  • Sequence:
    • MDLGPLNICE EMTILHGGFL LAEQLFHPKA LAELTKSDWE RVGRPIVEAL REISSAAAHS 
QPFAWKKKAL IIIWAKVLQP HPVTPSDTET RWQEDLFFSV GNMIPTINHT ILFELLKSLE 
ASGLFIQLLM ALPTTICHAE LERFLEHVTV DTSAEDVAFF LDVWWEVMKH KGHPQDPLLS 
QFSAMAHKYL PALDEFPHPP KRLRSDPDAC PTMPLLAMLL RGLTQIQSRI LGPGRKCCAL 
ANLADMLTVF ALTEDDPQEV SATVYLDKLA TVISVWNSDT QNPYHQQALA EKVKEAERDV 
SLTSLAKLPS ETIFVGCEFL HHLLREWGEE LQAVLRSSQG TSYDSYRLCD SLTSFSQNAT 
LYLNRTSLSK EDRQVVSELA ECVRDFLRKT STVLKNRALE DITASIAMAV IQQKMDRHME 
VCYIFASEKK WAFSDEWVAC LGSNRALFRQ PDLVLRLLET VIDVSTADRA IPESQIRQVI 
HLILECYADL SLPGKNKVLA GILRSWGRKG LSEKLLAYVE GFQEDLNTTF NQLTQSASEQ 
GLAKAVASVA RLVIVHPEVT VKKMCSLAVV NLGTHKFLAQ ILTAFPALRF VEEQGPNSSA 
TFMVSCLKET VWMKFSTPKE EKQFLELLNC LMSPVKPQGI PVAALLEPDE VLKEFVLPFL 
RLDVEEVDLS LRIFIQTLEA NACREEYWLQ TCSPFPLLFS LCQLLDRFSK YWQLPKEKRC 
LSLDRKDLAI HILELLCEIV SANAETFSPD VWIKSLSWLH RKLEQLDWTV GLRLKSFFEG 
HFKCEVPATL FEICKLSEDE WTSQAHPGYG AGTGLLAWME CCCVSSGISE RMLSLLVVDV 
GNPEEVRLFS KGFLVALVQV MPWCSPQEWQ RLHQLTRRLL EKQLLHVPYS LEYIQFVPLL 
NLKPFAQELQ LSVLFLRTFQ FLCSHSCRDW LPLEGWNHVV KLLCGSLTRL LDSVRAIQAA 
GPWVQGPEQD LTQEALFVYT QVFCHALHIM AMLHPEVCEP LYVLALETLT CYETLSKTNP 
SVSSLLQRAH EQRFLKSIAE GIGPEERRQT LLQKMSSF

Genular Protein ID: 2574977476

Symbol: Q8WUM5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8WUM5

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 IntAct 1 InterPro 1 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1058
  • Mass: 120041
  • Checksum: 0152053BF3423ADD
  • Sequence:
    • MDLGPLNICE EMTILHGGFL LAEQLFHPKA LAELTKSDWE RVGRPIVEAL REISSAAAHS 
QPFAWKKKAL IIIWAKVLQP HPVTPSDTET RWQEDLFFSV GNMIPTINHT ILFELLKSLE 
ASGLFIQLLM ALPTTICHAE LERFLEHVTV DTSAEDVAFF LDVWWEVMKH KGHPQDPLLS 
QFSAMAHKYL PALDEFPHPP KRLRSDPDAC PTMPLLAMLL RGLTQIQSRI LGPGRKCCAL 
ANLADMLTVF ALTEDDPQEV SATVYLDKLA TVISVWNSDT QNPYHQQALA EKVKEAERDV 
SLTSLAKLPS ETIFVGCEFL HHLLREWGEE LQAVLRSSQG TSYDSYRLCD SLTSFSQNAT 
LYLNRTSLSK EDRQVVSELA ECVRDFLRKT STVLKNRALE DITASIAMAV IQQKMDRHME 
VCYIFASEKK WAFSDEWVAC LGSNRALFRE PDLVLRLLET VIDVSTADRA IPESQIRQVI 
HLILECYADL SLPGKNKVLA GILRSWGRKG LSEKLLAYVE GFQEDLNTTF NQLTQSASEQ 
GLAKAVASVA RLVIVHPEVT VKKMCSLAVV NLGTHKFLGQ ILTAFPALRF VEEQGPNSSA 
TFMVSCLKET VWMKFSTPKE EKQFLELLNC LMSPVKPQGI PVAALLEPDE VLKEFVLPFL 
RLDVEEVDLS LRIFIQTLEA NACREEYWLQ TCSPFPLLFS LCQLLDRFSK YWQLPKEKRC 
LSLDRKDLAI HILELLCEIV SANAETFSPD VWIKSLSWLH RKLEQLDWTV GLRLKSFFEG 
HFKCEVPATL FEICKLSEDE WTSQAHPGYG AGTGLLAWME CCCVSSGISE RMLSLLVVDV 
GNPEEVRLFS KGFLVALVQV MPWCSPQEWQ RLHQLTRRLL EKQLLHVPYS LEYIQFVPLL 
NLKPFAQELQ LSVLFLRTFQ FLCSHSCRNW LPLEGWNHVV KLLCGSLTRL LDSVRAIQAA 
GPWVQGPEQD LTQEALFVYT QVFCHALHIM AMLHPEVCEP LYVLSIETLT CYETLSKTNP 
SVSSLRSRAH EQRFLKSIAE GIGPEERRQT LLQKMSSF

Genular Protein ID: 4110818197

Symbol: I3L2C7_HUMAN

Name: N/A

UniProtKB Accession Codes:

I3L2C7

Database IDs:

AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 5 GeneTree 1 HGNC 1 HOGENOM 1 IntAct 1 InterPro 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 2 RefSeq 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 1047
  • Mass: 118822
  • Checksum: C4ACEED2A80E1BD3
  • Sequence:
    • MTILHGGFLL AEQLFHPKAL AELTKSDWER VGRPIVEALR EISSAAAHSQ PFAWKKKALI 
IIWAKVLQPH PVTPSDTETR WQEDLFFSVG NMIPTINHTI LFELLKSLEA SGLFIQLLMA 
LPTTICHAEL ERFLEHVTVD TSAEDVAFFL DVWWEVMKHK GHPQDPLLSQ FSAMAHKYLP 
ALDEFPHPPK RLRSDPDACP TMPLLAMLLR GLTQIQSRIL GPGRKCCALA NLADMLTVFA 
LTEDDPQEVS ATVYLDKLAT VISVWNSDTQ NPYHQQALAE KVKEAERDVS LTSLAKLPSE 
TIFVGCEFLH HLLREWGEEL QAVLRSSQGT SYDSYRLCDS LTSFSQNATL YLNRTSLSKE 
DRQVVSELAE CVRDFLRKTS TVLKNRALED ITASIAMAVI QQKMDRHMEV CYIFASEKKW 
AFSDEWVACL GSNRALFRQP DLVLRLLETV IDVSTADRAI PESQIRQVIH LILECYADLS 
LPGKNKVLAG ILRSWGRKGL SEKLLAYVEG FQEDLNTTFN QLTQSASEQG LAKAVASVAR 
LVIVHPEVTV KKMCSLAVVN LGTHKFLAQI LTAFPALRFV EEQGPNSSAT FMVSCLKETV 
WMKFSTPKEE KQFLELLNCL MSPVKPQGIP VAALLEPDEV LKEFVLPFLR LDVEEVDLSL 
RIFIQTLEAN ACREEYWLQT CSPFPLLFSL CQLLDRFSKY WQLPKEKRCL SLDRKDLAIH 
ILELLCEIVS ANAETFSPDV WIKSLSWLHR KLEQLDWTVG LRLKSFFEGH FKCEVPATLF 
EICKLSEDEW TSQAHPGYGA GTGLLAWMEC CCVSSGISER MLSLLVVDVG NPEEVRLFSK 
GFLVALVQVM PWCSPQEWQR LHQLTRRLLE KQLLHVPYSL EYIQFVPLLN LKPFAQELQL 
SVLFLRTFQF LCSHSCRDWL PLEGWNHVVK LLCGSLTRLL DSVRAIQAAG PWVQGPEQDL 
TQEALFVYTQ VFCHALHIMA MLHPEVCEPL YVLALETLTC YETLSKTNPS VSSLLQRAHE 
QRFLKSIAEG IGPEERRQTL LQKMSSF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.