Details for: SEPSECS

Gene ID: 51091

Symbol: SEPSECS

Ensembl ID: ENSG00000109618

Description: Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 95.5671
    Cell Significance Index: -14.8700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 59.0593
    Cell Significance Index: -14.9800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 33.0529
    Cell Significance Index: -15.6100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 31.7533
    Cell Significance Index: -12.9000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 13.5639
    Cell Significance Index: -12.9500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 12.5106
    Cell Significance Index: -15.4300
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.6741
    Cell Significance Index: -15.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.9457
    Cell Significance Index: -15.5700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.7010
    Cell Significance Index: -8.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6566
    Cell Significance Index: 163.8800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0149
    Cell Significance Index: 110.3900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9962
    Cell Significance Index: 59.8100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8206
    Cell Significance Index: 133.4600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.7005
    Cell Significance Index: 11.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5667
    Cell Significance Index: 39.1900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5359
    Cell Significance Index: 106.3500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5260
    Cell Significance Index: 15.1600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3797
    Cell Significance Index: 5.1800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3711
    Cell Significance Index: 8.0400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.3337
    Cell Significance Index: 38.8900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3086
    Cell Significance Index: 13.9900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2284
    Cell Significance Index: 41.1800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2268
    Cell Significance Index: 204.7700
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.1821
    Cell Significance Index: 3.5600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1793
    Cell Significance Index: 35.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1722
    Cell Significance Index: 32.7800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.1712
    Cell Significance Index: 4.4000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1603
    Cell Significance Index: 12.3100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1485
    Cell Significance Index: 102.7300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1150
    Cell Significance Index: 2.4500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1149
    Cell Significance Index: 41.2100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0937
    Cell Significance Index: 5.2600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0814
    Cell Significance Index: 2.8600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0603
    Cell Significance Index: 3.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0583
    Cell Significance Index: 2.7200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0554
    Cell Significance Index: 30.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0458
    Cell Significance Index: 1.2800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0437
    Cell Significance Index: 19.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0421
    Cell Significance Index: 5.7800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0392
    Cell Significance Index: 4.8200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0211
    Cell Significance Index: 39.6800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0106
    Cell Significance Index: 19.5800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0094
    Cell Significance Index: 0.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0091
    Cell Significance Index: 5.7900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0084
    Cell Significance Index: 3.8200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0058
    Cell Significance Index: 8.9200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0015
    Cell Significance Index: -0.2500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0036
    Cell Significance Index: -4.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0048
    Cell Significance Index: -0.3000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0102
    Cell Significance Index: -1.3100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0107
    Cell Significance Index: -7.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0176
    Cell Significance Index: -13.0400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0195
    Cell Significance Index: -14.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0223
    Cell Significance Index: -3.2400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0257
    Cell Significance Index: -14.4900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0278
    Cell Significance Index: -17.3700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0312
    Cell Significance Index: -0.4600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0315
    Cell Significance Index: -3.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0414
    Cell Significance Index: -4.2300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0438
    Cell Significance Index: -12.5900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0537
    Cell Significance Index: -1.4400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0580
    Cell Significance Index: -4.1000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0599
    Cell Significance Index: -3.8700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0622
    Cell Significance Index: -7.1300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0777
    Cell Significance Index: -16.3700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0959
    Cell Significance Index: -2.5600
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1036
    Cell Significance Index: -0.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1065
    Cell Significance Index: -13.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1079
    Cell Significance Index: -5.0700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1108
    Cell Significance Index: -7.4500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1232
    Cell Significance Index: -12.8300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1257
    Cell Significance Index: -6.5500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1517
    Cell Significance Index: -2.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1542
    Cell Significance Index: -12.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1612
    Cell Significance Index: -4.0300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1652
    Cell Significance Index: -12.3100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1759
    Cell Significance Index: -8.8900
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.1765
    Cell Significance Index: -2.6400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2027
    Cell Significance Index: -8.9700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2079
    Cell Significance Index: -6.6600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2139
    Cell Significance Index: -13.1200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2186
    Cell Significance Index: -5.9500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2304
    Cell Significance Index: -4.9300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2318
    Cell Significance Index: -6.2000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2344
    Cell Significance Index: -3.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2393
    Cell Significance Index: -9.0600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2604
    Cell Significance Index: -13.6700
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.2630
    Cell Significance Index: -4.2200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2901
    Cell Significance Index: -8.5200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2963
    Cell Significance Index: -7.7900
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.3054
    Cell Significance Index: -4.3400
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.3087
    Cell Significance Index: -2.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3115
    Cell Significance Index: -10.2000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3273
    Cell Significance Index: -6.8500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3331
    Cell Significance Index: -11.6700
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.3339
    Cell Significance Index: -4.7900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3358
    Cell Significance Index: -11.6700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3433
    Cell Significance Index: -10.9400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.3490
    Cell Significance Index: -5.8700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3515
    Cell Significance Index: -8.4300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SEPSECS is a tRNA-specific selenium transferase enzyme, crucial for the incorporation of selenocysteine into proteins. This process, mediated by SEPSECS, ensures the proper functioning of selenoproteins, which play vital roles in antioxidant defense, immune system regulation, and cellular homeostasis. Notably, SEPSECS is involved in the conversion of seryl-tRNA to selenocysteine-tRNA, a specific reaction necessary for selenocysteine incorporation into target proteins. **Pathways and Functions:** The SEPSECS gene is integral to several cellular pathways, including: 1. **Selenocysteine Synthesis**: SEPSECS is responsible for converting seryl-tRNA to selenocysteine-tRNA, a critical step in selenocysteine metabolism. 2. **Protein Binding**: SEPSECS interacts with various tRNA molecules, facilitating the incorporation of selenocysteine into target proteins. 3. **Antioxidant Defense**: Selenoproteins, which rely on SEPSECS for selenocysteine incorporation, play a vital role in mitigating oxidative stress and maintaining cellular homeostasis. 4. **Immune System Regulation**: SEPSECS is expressed in various immune cells, suggesting its involvement in immune system function and regulation. **Clinical Significance:** The elucidation of SEPSECS's role in selenocysteine metabolism has significant implications for our understanding of immune system disorders. Dysregulation of selenocysteine metabolism has been implicated in various diseases, including: 1. **Autoimmune Disorders**: Imbalances in selenocysteine metabolism may contribute to autoimmune diseases, such as rheumatoid arthritis and lupus. 2. **Neurodegenerative Diseases**: Selenoprotein dysfunction has been linked to neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer**: SEPSECS expression has been observed in various types of cancer, suggesting its potential role in cancer development and progression. In conclusion, the SEPSECS gene is a crucial component of selenocysteine metabolism, with significant implications for our understanding of immune system function and regulation. Further research into the pathways and functions of SEPSECS will provide valuable insights into the clinical significance of this gene and its potential applications in the treatment of immune-related disorders.

Genular Protein ID: 236608983

Symbol: SPCS_HUMAN

Name: O-phosphoseryl-tRNA(Sec) selenium transferase

UniProtKB Accession Codes:

Q9HD40 A8K8W1 Q0D2P3 Q17RT1 Q9NXZ5 Q9UGM9 Q9Y353

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChEBI 10 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EC 1 EMBL 11 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 Rhea 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10801173

Title: Identification of target antigen for SLA/LP autoantibodies in autoimmune hepatitis.

PubMed ID: 10801173

DOI: 10.1016/s0140-6736(00)02166-8

PubMed ID: 10931155

Title: Isolation and characterization of cDNA encoding the antigenic protein of the human tRNP(Ser)Sec complex recognized by autoantibodies from patients with type-1 autoimmune hepatitis.

PubMed ID: 10931155

DOI: 10.1046/j.1365-2249.2000.01280.x

PubMed ID: 11230739

Title: Soluble liver antigen: isolation of a 35-kd recombinant protein (SLA-p35) specifically recognizing sera from patients with autoimmune hepatitis.

PubMed ID: 11230739

DOI: 10.1053/jhep.2001.22218

PubMed ID: 11826415

Title: Fine specificity of autoantibodies to soluble liver antigen and liver/pancreas.

PubMed ID: 11826415

DOI: 10.1053/jhep.2002.30699

PubMed ID: 17142313

Title: RNA-dependent conversion of phosphoserine forms selenocysteine in eukaryotes and archaea.

PubMed ID: 17142313

DOI: 10.1073/pnas.0609703104

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 19608919

Title: The human SepSecS-tRNASec complex reveals the mechanism of selenocysteine formation.

PubMed ID: 19608919

DOI: 10.1126/science.1173755

PubMed ID: 20920667

Title: Mutations disrupting selenocysteine formation cause progressive cerebello-cerebral atrophy.

PubMed ID: 20920667

DOI: 10.1016/j.ajhg.2010.09.007

PubMed ID: 26115735

Title: Selenoprotein biosynthesis defect causes progressive encephalopathy with elevated lactate.

PubMed ID: 26115735

DOI: 10.1212/wnl.0000000000001787

Sequence Information:

  • Length: 501
  • Mass: 55726
  • Checksum: 7136FB390B18760B
  • Sequence:
    • MNRESFAAGE RLVSPAYVRQ GCEARRSHEH LIRLLLEKGK CPENGWDEST LELFLHELAI 
MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS 
LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI 
TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV 
ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND 
SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN 
ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR 
GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD 
IEEMALKLDN VLLDTYQDAS S

Genular Protein ID: 1216137735

Symbol: A1A4F3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A1A4F3

Database IDs:

ARBA 15 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 10 ChiTaRS 1 DNASU 1 DisGeNET 1 EC 1 EMBL 4 GO 5 Gene3D 1 InterPro 4 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 3 SMR 1 SUPFAM 1 UniPathway 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 441
  • Mass: 48836
  • Checksum: DF8F2FF846061F46
  • Sequence:
    • MDSNNFLGNC GVGEREGRVA SALVARRHYR FIHGIGRSGD ISAVQPKAAG SSLLNKITNS 
LVLDIIKLAG VHTVANCFVV PMATGMSLTL CFLTLRHKRP KAKYIIWPRI DQKSCFKSMI 
TAGFEPVVIE NVLEGDELRT DLKAVEAKVQ ELGPDCILCI HSTTSCFAPR VPDRLEELAV 
ICANYDIPHI VNNAYGVQSS KCMHLIQQGA RVGRIDAFVQ SLDKNFMVPV GGAIIAGFND 
SFIQEISKMY PGRASASPSL DVLITLLSLG SNGYKKLLKE RKEMFSYLSN QIKKLSEAYN 
ERLLHTPHNP ISLAMTLKTL DEHRDKAVTQ LGSMLFTRQV SGARVVPLGS MQTVSGYTFR 
GFMSHTNNYP CAYLNAASAI GMKMQDVDLF IKRLDRCLKA VRKERSKESD DNYDKTEDVD 
IEEMALKLDN VLLDTYQDAS S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.