Details for: SPTBN5
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 5.0340
Cell Significance Index: 317.2800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 4.1936
Cell Significance Index: 49.9900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.1412
Cell Significance Index: 111.2300 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 1.7495
Cell Significance Index: 14.8700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.8940
Cell Significance Index: 28.6400 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.4774
Cell Significance Index: 6.7100 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.3430
Cell Significance Index: 5.1400 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.3117
Cell Significance Index: 2.8700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.1685
Cell Significance Index: 3.6900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.1402
Cell Significance Index: 10.7600 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 0.1279
Cell Significance Index: 1.3700 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.1251
Cell Significance Index: 8.8500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: 0.1168
Cell Significance Index: 4.0600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.1167
Cell Significance Index: 16.9600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1094
Cell Significance Index: 6.5700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1019
Cell Significance Index: 70.4800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0947
Cell Significance Index: 17.0800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.0884
Cell Significance Index: 4.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0789
Cell Significance Index: 1.7100 - Cell Name: retinal cone cell (CL0000573)
Fold Change: 0.0785
Cell Significance Index: 0.9800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0739
Cell Significance Index: 14.0700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0693
Cell Significance Index: 13.7500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0654
Cell Significance Index: 13.1200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.0535
Cell Significance Index: 0.7300 - Cell Name: myometrial cell (CL0002366)
Fold Change: 0.0512
Cell Significance Index: 0.5900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.0453
Cell Significance Index: 0.9700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0382
Cell Significance Index: 4.1600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0382
Cell Significance Index: 1.1000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0335
Cell Significance Index: 1.5600 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0315
Cell Significance Index: 0.8800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0300
Cell Significance Index: 3.5000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0218
Cell Significance Index: 9.6400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0170
Cell Significance Index: 2.0900 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: 0.0097
Cell Significance Index: 0.0800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0082
Cell Significance Index: 15.4700 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0052
Cell Significance Index: 9.6600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 0.0039
Cell Significance Index: 0.2400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0028
Cell Significance Index: 4.2400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0017
Cell Significance Index: 1.0500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0006
Cell Significance Index: 0.7600 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: -0.0007
Cell Significance Index: -0.1200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0008
Cell Significance Index: -0.0800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0010
Cell Significance Index: -0.3700 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0017
Cell Significance Index: -0.9200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0018
Cell Significance Index: -0.0800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0037
Cell Significance Index: -0.2600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0041
Cell Significance Index: -1.8600 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0041
Cell Significance Index: -3.0000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0044
Cell Significance Index: -3.3600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0049
Cell Significance Index: -3.6200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0053
Cell Significance Index: -0.1900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0059
Cell Significance Index: -3.3300 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.0074
Cell Significance Index: -0.1000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0096
Cell Significance Index: -2.7500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0096
Cell Significance Index: -0.2000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0112
Cell Significance Index: -1.9200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0119
Cell Significance Index: -0.1700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0120
Cell Significance Index: -1.5400 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0134
Cell Significance Index: -0.2300 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0146
Cell Significance Index: -0.2200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0155
Cell Significance Index: -1.7800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0159
Cell Significance Index: -1.6600 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0173
Cell Significance Index: -1.7700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0175
Cell Significance Index: -3.6900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0190
Cell Significance Index: -2.4600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0208
Cell Significance Index: -0.9800 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.0208
Cell Significance Index: -0.1700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0212
Cell Significance Index: -2.9100 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.0218
Cell Significance Index: -0.2800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0224
Cell Significance Index: -0.5600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0227
Cell Significance Index: -1.6900 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: -0.0239
Cell Significance Index: -0.2900 - Cell Name: taste receptor cell (CL0000209)
Fold Change: -0.0241
Cell Significance Index: -0.2800 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0254
Cell Significance Index: -3.0000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0264
Cell Significance Index: -0.7100 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0337
Cell Significance Index: -1.1000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0366
Cell Significance Index: -0.5400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0371
Cell Significance Index: -1.0100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0372
Cell Significance Index: -2.5000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0391
Cell Significance Index: -2.5200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0396
Cell Significance Index: -3.1400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0435
Cell Significance Index: -0.5800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0451
Cell Significance Index: -2.2800 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0516
Cell Significance Index: -0.8500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0527
Cell Significance Index: -2.9600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0537
Cell Significance Index: -1.7100 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0555
Cell Significance Index: -0.8200 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0556
Cell Significance Index: -2.9000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0578
Cell Significance Index: -2.1200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0634
Cell Significance Index: -2.2200 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0717
Cell Significance Index: -2.9400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0742
Cell Significance Index: -3.2800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0782
Cell Significance Index: -0.8100 - Cell Name: glandular epithelial cell (CL0000150)
Fold Change: -0.0792
Cell Significance Index: -0.6300 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0812
Cell Significance Index: -3.5300 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0832
Cell Significance Index: -1.3200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0856
Cell Significance Index: -3.2400 - Cell Name: neuroendocrine cell (CL0000165)
Fold Change: -0.0861
Cell Significance Index: -1.0900 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0862
Cell Significance Index: -1.4500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2944135158
Symbol: SPTN5_HUMAN
Name: Spectrin beta chain, non-erythrocytic 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10764729
Title: Identification and characterization of beta V spectrin, a mammalian ortholog of Drosophila beta H spectrin.
PubMed ID: 10764729
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
PubMed ID: 18048348
Title: The spectrin cytoskeleton influences the surface expression and activation of human transient receptor potential channel 4 channels.
PubMed ID: 18048348
Sequence Information:
- Length: 3674
- Mass: 416750
- Checksum: 83D1F94ADE670E13
- Sequence:
MAGQPHSPRE LLGAAGHRSR RPSTELRVPP SPSLTMDSQY ETGHIRKLQA RHMQMQEKTF TKWINNVFQC GQAGIKIRNL YTELADGIHL LRLLELISGE ALPPPSRGRL RVHFLENSSR ALAFLRAKVP VPLIGPENIV DGDQTLILGL IWVIILRFQI SHISLDKEEF GASAALLSTK EALLVWCQRK TASYTNVNIT DFSRSWSDGL GFNALIHAHR PDLLDYGSLR PDRPLHNLAF AFLVAEQELG IAQLLDPEDV AAAQPDERSI MTYVSLYYHY CSRLHQGQTV QRRLTKILLQ LQETELLQTQ YEQLVADLLR WIAEKQMQLE ARDFPDSLPA MRQLLAAFTI FRTQEKPPRL QQRGAAEALL FRLQTALQAQ NRRPFLPHEG LGLAELSQCW AGLEWAEAAR SQALQQRLLQ LQRLETLARR FQHKAALRES FLKDAEQVLD QARAPPASLA TVEAAVQRLG MLEAGILPQE GRFQALAEIA DILRQEQYHS WADVARRQEE VTVRWQRLLQ HLQGQRKQVA DMQAVLSLLQ EVEAASHQLE ELQEPARSTA CGQQLAEVVE LLQRHDLLEA QVSAHGAHVS HLAQQTAELD SSLGTSVEVL QAKARTLAQL QQSLVALVRA RRALLEQTLQ RAEFLRNCEE EEAWLKECGQ RVGNAALGRD LSQIAGALQK HKALEAEVHR HQAVCVDLVR RGRDLSARRP PTQPDPGERA EAVQGGWQLL QTRVVGRGAR LQTALLVLQY FADAAEAASW LRERRSSLER ASCGQDQAAA ETLLRRHVRL ERVLRAFAAE LRRLEEQGRA ASARASLFTV NSALSPPGES LRNPGPWSEA SCHPGPGDAW KMALPAEPDP DFDPNTILQT QDHLSQDYES LRALAQLRRA RLEEAMALFG FCSSCGELQL WLEKQTVLLQ RVQPQADTLE VMQLKYENFL TALAVGKGLW AEVSSSAEQL RQRYPGNSTQ IQRQQEELSQ RWGQLEALKR EKAVQLAHSV EVCSFLQECG PTQVQLRDVL LQLEALQPGS SEDTCHALQL AQKKTLVLER RVHFLQSVVV KVEEPGYAES QPLQGQVETL QGLLKQVQEQ VAQRARRQAE TQARQSFLQE SQQLLLWAES VQAQLRSKEV SVDVASAQRL LREHQDLLEE IHLWQERLQQ LDAQSQPMAA LDCPDSQEVP NTLRVLGQQG QELKVLWEQR QQWLQEGLEL QKFGREVDGF TATCANHQAW LHLDNLGEDV REALSLLQQH REFGRLLSTL GPRAEALRAH GEKLVQSQHP AAHTVREQLQ SIQAQWTRLQ GRSEQRRRQL LASLQLQEWK QDVAELMQWM EEKGLMAAHE PSGARRNILQ TLKRHEAAES ELLATRRHVE ALQQVGRELL SRRPCGQEDI QTRLQGLRSK WEALNRKMTE RGDELQQAGQ QEQLLRQLQD AKEQLEQLEG ALQSSETGQD LRSSQRLQKR HQQLESESRT LAAKMAALAS MAHGMAASPA ILEETQKHLR RLELLQGHLA IRGLQLQASV ELHQFCHLSN MELSWVAEHM PHGSPTSYTE CLNGAQSLHR KHKELQVEVK AHQGQVQRVL SSGRSLAASG HPQAQHIVEQ CQELEGHWAE LERACEARAQ CLQQAVTFQQ YFLDVSELEG WVEEKRPLVS SRDYGRDEAA TLRLINKHQA LQEELAIYWS SMEELDQTAQ TLTGPEVPEQ QRVVQERLRE QLRALQELAA TRDRELEGTL RLHEFLREAE DLQGWLASQK QAAKGGESLG EDPEHALHLC TKFAKFQHQV EMGSQRVAAC RLLAESLLER GHSAGPMVRQ RQQDLQTAWS ELWELTQARG HALRDTETTL RVHRDLLEVL TQVQEKATSL PNNVARDLCG LEAQLRSHQG LERELVGTER QLQELLETAG RVQKLCPGPQ AHAVQQRQQA VTQAWAVLQR RMEQRRAQLE RARLLARFRT AVRDYASWAA RVRQDLQVEE SSQEPSSGPL KLSAHQWLRA ELEAREKLWQ QATQLGQQAL LAAGTPTKEV QEELRALQDQ RDQVYQTWAR KQERLQAEQQ EQLFLRECGR LEEILAAQEV SLKTSALGSS VEEVEQLIRK HEVFLKVLTA QDKKEAALRE RLKTLRRPRV RDRLPILLQR RMRVKELAES RGHALHASLL MASFTQAATQ AEDWIQAWAQ QLKEPVPPGD LRDKLKPLLK HQAFEAEVQA HEEVMTSVAK KGEALLAQSH PRAGEVSQRL QGLRKHWEDL RQAMALRGQE LEDRRNFLEF LQRVDLAEAW IQEKEVKMNV GDLGQDLEHC LQLRRRLREF RGNSAGDTVG DACIRSISDL SLQLKNRDPE EVKIICQRRS QLNNRWASFH GNLLRYQQQL EGALEIHVLS RELDNVTKRI QEKEALIQAL DCGKDLESVQ RLLRKHEELE REVHPIQAQV ESLEREVGRL CQRSPEAAHG LRHRQQEVAE SWWQLRSRAQ KRREALDALH QAQKLQAMLQ ELLVSAQRLR AQMDTSPAPR SPVEARRMLE EHQECKAELD SWTDSISLAR STGQQLLTAG HPFSSDIRQV LAGLEQELSS LEGAWQEHQL QLQQALELQL FLSSVEKMER WLCSKEDSLA SEGLWDPLAP MEPLLWKHKM LEWDLEVQAG KISALEATAR GLHQGGHPEA QSALGRCQAM LLRKEALFRQ AGTRRHRLEE LRQLQAFLQD SQEVAAWLRE KNLVALEEGL LDTAMLPAQL QKQQNFQAEL DASMHQQQEL QREGQRLLQG GHPASEAIQE RLEELGALWG ELQDNSQKKV AKLQKACEAL RLRRSMEELE NWLEPIEVEL RAPTVGQALP GVGELLGTQR ELEAAVDKKA RQAEALLGQA QAFVREGHCL AQDVEEQARR LLQRFKSLRE PLQERRTALE ARSLLLKFFR DADEEMAWVQ EKLPLAAAQD YGQSLSAVRH LQEQHQNLES EMSSHEALTR VVLGTGYKLV QAGHFAAHEV AARVQQLEKA MAHLRAEAAR RRLLLQQAQE AQQFLTELLE AGSWLAERGH VLDSEDMGHS AEATQALLRR LEATKRDLEA FSPRIERLQQ TAALLESRKN PESPKVLAQL QAVREAHAEL LRRAEARGHG LQEQLQLHQL ERETLLLDAW LTTKAATAES QDYGQDLEGV KVLEEKFDAF RKEVQSLGQA KVYALRKLAG TLERGAPRRY PHIQAQRSRI EAAWERLDQA IKARTENLAA AHEVHSFQQA AAELQGRMQE KTALMKGEDG GHSLSSVRTL QQQHRRLERE LEAMEKEVAR LQTEACRLGQ LHPAAPGGLA KVQEAWATLQ AKAQERGQWL AQAAQGHAFL GRCQELLAWA QERQELASSE ELAEDVAGAE QLLGQHEELG QEIRECRLQA QDLRQEGQQL VDNSHFMSAE VTECLQELEG RLQELEEAWA LRWQRCAESW GLQKLRQRLE QAEAWLACWE GLLLKPDYGH SVSDVELLLH RHQDLEKLLA AQEEKFAQMQ KTEMEQELLL QPQELKPGRA GSSLTSFQWR PSGHQGLGAQ LAETRDPQDA KGTPTMEGSL EFKQHLLPGG RQPSSSSWDS CRGNLQGSSL SLFLDERMAA EKVASIALLD LTGARCERLR GRHGRKHTFS LRLTSGAEIL FAAPSEEQAE SWWRALGSTA AQSLSPKLKA KPVSSLNECT TKDARPGCLL RSDP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.