Details for: ANKFY1

Gene ID: 51479

Symbol: ANKFY1

Ensembl ID: ENSG00000185722

Description: ankyrin repeat and FYVE domain containing 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 254.3955
    Cell Significance Index: -39.5700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 158.4114
    Cell Significance Index: -40.1800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 88.3033
    Cell Significance Index: -41.6900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 81.6970
    Cell Significance Index: -33.1900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 75.3715
    Cell Significance Index: -38.7700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 34.7633
    Cell Significance Index: -33.1900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 33.2696
    Cell Significance Index: -41.0200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 14.4240
    Cell Significance Index: -38.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.5042
    Cell Significance Index: -41.4500
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 10.1253
    Cell Significance Index: -22.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9107
    Cell Significance Index: 383.2900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.3951
    Cell Significance Index: 96.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.2515
    Cell Significance Index: 96.0400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.1363
    Cell Significance Index: 50.2600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.0719
    Cell Significance Index: 40.5900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.0528
    Cell Significance Index: 377.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0482
    Cell Significance Index: 208.0100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8130
    Cell Significance Index: 132.2300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8063
    Cell Significance Index: 557.6500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7928
    Cell Significance Index: 17.3600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.7622
    Cell Significance Index: 21.3000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7434
    Cell Significance Index: 80.8600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.6609
    Cell Significance Index: 37.0900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.6395
    Cell Significance Index: 8.7200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.6257
    Cell Significance Index: 72.9200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5596
    Cell Significance Index: 37.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5345
    Cell Significance Index: 32.8500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5100
    Cell Significance Index: 14.7000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4173
    Cell Significance Index: 51.3100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4126
    Cell Significance Index: 74.3800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3043
    Cell Significance Index: 5.9400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2173
    Cell Significance Index: 118.6500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2146
    Cell Significance Index: 9.7300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1848
    Cell Significance Index: 348.0400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1611
    Cell Significance Index: 30.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1609
    Cell Significance Index: 22.0900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1400
    Cell Significance Index: 61.8800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1314
    Cell Significance Index: 1.6300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.0922
    Cell Significance Index: 2.2100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0917
    Cell Significance Index: 169.1200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0901
    Cell Significance Index: 4.6800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0852
    Cell Significance Index: 1.4600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0602
    Cell Significance Index: 92.6700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0546
    Cell Significance Index: 24.7900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0529
    Cell Significance Index: 1.8600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0480
    Cell Significance Index: 30.5100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0319
    Cell Significance Index: 28.8300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0272
    Cell Significance Index: 37.0200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0124
    Cell Significance Index: -2.1100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0194
    Cell Significance Index: -14.3900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0245
    Cell Significance Index: -1.1400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.0264
    Cell Significance Index: -2.6100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0274
    Cell Significance Index: -20.0900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0309
    Cell Significance Index: -19.3100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0374
    Cell Significance Index: -0.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0396
    Cell Significance Index: -22.3600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0432
    Cell Significance Index: -32.7100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0661
    Cell Significance Index: -1.7000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0921
    Cell Significance Index: -2.4600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1007
    Cell Significance Index: -11.8800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1046
    Cell Significance Index: -11.9800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1105
    Cell Significance Index: -14.1700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1121
    Cell Significance Index: -23.6200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1174
    Cell Significance Index: -3.3500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1213
    Cell Significance Index: -34.9100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1238
    Cell Significance Index: -7.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1342
    Cell Significance Index: -19.5100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1405
    Cell Significance Index: -14.3500
  • Cell Name: slow muscle cell (CL0000189)
    Fold Change: -0.1477
    Cell Significance Index: -2.2100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2338
    Cell Significance Index: -4.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2367
    Cell Significance Index: -30.5900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2455
    Cell Significance Index: -15.4700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2464
    Cell Significance Index: -12.9400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2725
    Cell Significance Index: -28.3800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2764
    Cell Significance Index: -19.5500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.2862
    Cell Significance Index: -13.4500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2882
    Cell Significance Index: -32.9000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3504
    Cell Significance Index: -8.7600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3625
    Cell Significance Index: -18.8800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3664
    Cell Significance Index: -27.3100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4362
    Cell Significance Index: -13.9700
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.4372
    Cell Significance Index: -3.5700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4383
    Cell Significance Index: -34.7200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4411
    Cell Significance Index: -5.5000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4477
    Cell Significance Index: -6.6100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4819
    Cell Significance Index: -13.1200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5254
    Cell Significance Index: -11.1900
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.5331
    Cell Significance Index: -7.6600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5583
    Cell Significance Index: -34.2300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.5747
    Cell Significance Index: -12.4500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5885
    Cell Significance Index: -12.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5986
    Cell Significance Index: -16.0400
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.6188
    Cell Significance Index: -7.8100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.6228
    Cell Significance Index: -20.3900
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.6296
    Cell Significance Index: -12.4500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.6308
    Cell Significance Index: -20.0900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.6535
    Cell Significance Index: -13.1200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.6543
    Cell Significance Index: -7.8000
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.6754
    Cell Significance Index: -16.4800
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.7054
    Cell Significance Index: -10.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The ANKFY1 gene exhibits several key characteristics that define its function: 1. **Ankyrin repeat domain**: The ANKFY1 protein contains ankyrin repeat domains, which are known to be involved in protein-protein interactions and binding to phospholipids. 2. **FYVE domain**: The FYVE domain is a conserved motif found in many endosomal proteins, which is essential for endocytosis and retrograde transport. 3. **Multifunctional protein**: ANKFY1 is expressed in a wide range of cell types, suggesting its involvement in various cellular processes, including endocytosis, intracellular transport, and signaling. 4. **Cell-type specific expression**: ANKFY1 is expressed in hematopoietic cells, smooth muscle cells, and immune cells, highlighting its role in tissue development and function. **Pathways and Functions** The ANKFY1 protein is involved in several cellular pathways, including: 1. **Endocytosis**: ANKFY1 is involved in the regulation of endocytosis, including pinocytosis and macropinocytosis. 2. **Intracellular transport**: ANKFY1 is involved in the regulation of retrograde transport, which is essential for the movement of proteins and lipids between the endoplasmic reticulum and the Golgi apparatus. 3. **Endosomal transport**: ANKFY1 is involved in the regulation of endosomal transport, including the fusion of endosomes and the movement of endosomal vesicles. 4. **Signaling**: ANKFY1 is involved in signaling pathways, including the regulation of Rho GTPases and the activation of immune cells. **Clinical Significance** Dysregulation of the ANKFY1 gene has been implicated in various diseases, including: 1. **Cancer**: ANKFY1 has been shown to be overexpressed in certain types of cancer, including breast cancer and lung cancer. 2. **Immune disorders**: ANKFY1 has been implicated in immune disorders, including autoimmune diseases and immunodeficiency disorders. 3. **Neurodegenerative diseases**: ANKFY1 has been implicated in neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. In conclusion, the ANKFY1 gene is a multifunctional protein involved in various cellular processes, including endocytosis, intracellular transport, and signaling. Its dysregulation has been implicated in various diseases, highlighting its importance in tissue development and function. Further research is needed to fully elucidate the role of ANKFY1 in human disease and to develop therapeutic strategies to target this protein.

Genular Protein ID: 2255337139

Symbol: ANFY1_HUMAN

Name: Ankyrin repeat and FYVE domain-containing protein 1

UniProtKB Accession Codes:

Q9P2R3 A8KA65 Q5RKV4 Q9ULG5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CTD 1 ChEBI 8 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 4 ExpressionAtlas 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10940552

Title: Characterization and chromosomal mapping of a novel human gene, ANKHZN.

PubMed ID: 10940552

DOI: 10.1016/s0378-1119(00)00247-x

PubMed ID: 10574462

Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10574462

DOI: 10.1093/dnares/6.5.337

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15328530

Title: The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms.

PubMed ID: 15328530

DOI: 10.1371/journal.pbio.0020261

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22284051

Title: Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function.

PubMed ID: 22284051

DOI: 10.1111/j.1600-0854.2012.01334.x

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24102721

Title: RhoD binds the Rab5 effector Rabankyrin-5 and has a role in trafficking of the platelet-derived growth factor receptor.

PubMed ID: 24102721

DOI: 10.1111/tra.12121

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1169
  • Mass: 128399
  • Checksum: 589297CA4ACDDB56
  • Sequence:
    • MAEEEVAKLE KHLMLLRQEY VKLQKKLAET EKRCALLAAQ ANKESSSESF ISRLLAIVAD 
LYEQEQYSDL KIKVGDRHIS AHKFVLAARS DSWSLANLSS TKELDLSDAN PEVTMTMLRW 
IYTDELEFRE DDVFLTELMK LANRFQLQLL RERCEKGVMS LVNVRNCIRF YQTAEELNAS 
TLMNYCAEII ASHWDDLRKE DFSSMSAQLL YKMIKSKTEY PLHKAIKVER EDVVFLYLIE 
MDSQLPGKLN EADHNGDLAL DLALSRRLES IATTLVSHKA DVDMVDKSGW SLLHKGIQRG 
DLFAATFLIK NGAFVNAATL GAQETPLHLV ALYSSKKHSA DVMSEMAQIA EALLQAGANP 
NMQDSKGRTP LHVSIMAGNE YVFSQLLQCK QLDLELKDHE GSTALWLAVQ HITVSSDQSV 
NPFEDVPVVN GTSFDENSFA ARLIQRGSHT DAPDTATGNC LLQRAAGAGN EAAALFLATN 
GAHVNHRNKW GETPLHTACR HGLANLTAEL LQQGANPNLQ TEEALPLPKE AASLTSLADS 
VHLQTPLHMA IAYNHPDVVS VILEQKANAL HATNNLQIIP DFSLKDSRDQ TVLGLALWTG 
MHTIAAQLLG SGAAINDTMS DGQTLLHMAI QRQDSKSALF LLEHQADINV RTQDGETALQ 
LAIRNQLPLV VDAICTRGAD MSVPDEKGNP PLWLALANNL EDIASTLVRH GCDATCWGPG 
PGGCLQTLLH RAIDENNEPT ACFLIRSGCD VNSPRQPGAN GEGEEEARDG QTPLHLAASW 
GLEETVQCLL EFGANVNAQD AEGRTPIHVA ISSQHGVIIQ LLVSHPDIHL NVRDRQGLTP 
FACAMTFKNN KSAEAILKRE SGAAEQVDNK GRNFLHVAVQ NSDIESVLFL ISVHANVNSR 
VQDASKLTPL HLAVQAGSEI IVRNLLLAGA KVNELTKHRQ TALHLAAQQD LPTICSVLLE 
NGVDFAAVDE NGNNALHLAV MHGRLNNIRV LLTECTVDAE AFNLRGQSPL HILGQYGKEN 
AAAIFDLFLE CMPGYPLDKP DADGSTVLLL AYMKGNANLC RAIVRSGARL GVNNNQGVNI 
FNYQVATKQL LFRLLDMLSK EPPWCDGSYC YECTARFGVT TRKHHCRHCG RLLCHKCSTK 
EIPIIKFDLN KPVRVCNICF DVLTLGGVS

Genular Protein ID: 1762567129

Symbol: B3KPZ0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KPZ0

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 1 Gene3D 2 InterPro 10 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SMART 2 SUPFAM 3

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 1093
  • Mass: 120004
  • Checksum: 1143CECF1884F8CC
  • Sequence:
    • MSSCRRSWRR QRSAALSWLR RQTRRAAASP SSAVCWPSWQ TSTSRSSTDA NPEVTMTMLR 
WIYTDELEFR EDDVFLTELM KLANRFQLQL LRERCEKGVM SLVNVRNCIR FYQTAEELNA 
STLMNYCAEI IASHWDDLRK EDFSSMSAQL LYKMIKSKTE YPLHKAIKVE REDVVFLYLI 
EMDSQLPGKL NEADHNGDLA LDLALSRRLE SIATTLVSHK ADVDMVDKSG WSLLHKGIQR 
GDLFAATFLI KNGAFVNAAT LGAQETPLHL VALYSSKKHS ADVMSEMAQI AEALLQAGAN 
PNMQDSKGRT PLHVSIMAGN EYVFSQLLQC KQLDLELKDH EGSTALWLAV QHITVSSDQS 
VNPFEDVPVV NGTSFDENSF AARLIQRGSH TDAPDTATGN CLLQRAAGAG NEAAALFLAT 
NGAHVNHRNK WGETPLHTAC RHGLANLTAE LLQQGANPNL QTEEALPLPK EAASLTSLAD 
SVHLQTPLHM AIAYNHPDVV SVILEQKANA LHATNNLQII PDFSLKDSRD QTVLGLALWT 
GMHTIAAQLL GSGAAINDTM SDGQTLLHMA IQRQDSKSAL FLLEHQADIN VSRTQDGETA 
LQLAIRNQLP LVVDAICTRG ADMSVPDEKG NPPLWLALAN NLEDIASTLV RHGCDATCWG 
PGPGGCLQTL LHRAIDENNE PTACFLIRSG CDVNSPRQPG ANGEGEEEAR DGQTPLHLAA 
SWGLEETVQC LLEFGANVNA QDAEGRTPIH VAISSQHGVI IQLLVSHPDI HLNVRDRQGL 
TPFACAMTFK NNKSAEAILK RESGAAEQVD NKGRNFLHVA VQNSDIESVL FLISVHANVN 
SRVQDASKLT PLHLAVQAGS EIIVRNLLLA GAKVNELTKH RQTALHLAAQ QDLPTICSVL 
LENGVDFAAV DENGNNALHL AVMHGRLNNI RVLLTECTVD AEAFNLRGQS PLHILGQYGK 
ENAAAIFDLF LECMPGYPLD KPDADGSTVL LLAYMKGNAN LCRAIVRSGA RLGVNNNQGV 
NIFNYQVATK QLLFRLLDML SKEPPWCDGS YCYECTARFG VTTRKHHCRH CGRLLCHKCS 
TKEIPIIKFD LNK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.