Details for: SCLY

Gene ID: 51540

Symbol: SCLY

Ensembl ID: ENSG00000132330

Description: selenocysteine lyase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 64.4829
    Cell Significance Index: -10.0300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 41.0222
    Cell Significance Index: -10.4100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 24.6546
    Cell Significance Index: -11.6400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 22.5473
    Cell Significance Index: -9.1600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.5567
    Cell Significance Index: -10.5500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 3.9942
    Cell Significance Index: -10.7000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7807
    Cell Significance Index: 46.8700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6428
    Cell Significance Index: 128.9400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.4721
    Cell Significance Index: 51.3500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4596
    Cell Significance Index: 45.4700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4177
    Cell Significance Index: 23.4400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4101
    Cell Significance Index: 18.1400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4018
    Cell Significance Index: 30.8300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.3797
    Cell Significance Index: 14.3800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3736
    Cell Significance Index: 134.0100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3555
    Cell Significance Index: 245.8500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3079
    Cell Significance Index: 8.8700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3049
    Cell Significance Index: 275.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2451
    Cell Significance Index: 39.8600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2190
    Cell Significance Index: 15.1500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2119
    Cell Significance Index: 38.1900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1881
    Cell Significance Index: 9.5000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1742
    Cell Significance Index: 10.9800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1740
    Cell Significance Index: 3.7200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1077
    Cell Significance Index: 5.6000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0826
    Cell Significance Index: 1.0300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0817
    Cell Significance Index: 9.5200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0807
    Cell Significance Index: 15.3700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0789
    Cell Significance Index: 1.7100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0744
    Cell Significance Index: 4.5700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0662
    Cell Significance Index: 8.1400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.0347
    Cell Significance Index: 0.6000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0256
    Cell Significance Index: 0.5600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0250
    Cell Significance Index: 13.6300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0141
    Cell Significance Index: 1.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0093
    Cell Significance Index: 0.4200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0021
    Cell Significance Index: -0.9400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0053
    Cell Significance Index: -9.9400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0060
    Cell Significance Index: -0.7100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0070
    Cell Significance Index: -12.8400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0082
    Cell Significance Index: -12.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0098
    Cell Significance Index: -13.3400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0116
    Cell Significance Index: -8.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0120
    Cell Significance Index: -0.4200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0133
    Cell Significance Index: -9.8600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0144
    Cell Significance Index: -10.8900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0153
    Cell Significance Index: -9.7100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0161
    Cell Significance Index: -9.0900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0212
    Cell Significance Index: -13.2600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0233
    Cell Significance Index: -10.5700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0304
    Cell Significance Index: -0.7300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0318
    Cell Significance Index: -9.1600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0371
    Cell Significance Index: -4.7600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0380
    Cell Significance Index: -0.8100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0454
    Cell Significance Index: -7.7500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0457
    Cell Significance Index: -5.2400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0481
    Cell Significance Index: -4.9100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0577
    Cell Significance Index: -12.1600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0623
    Cell Significance Index: -12.3600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0649
    Cell Significance Index: -2.0800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0649
    Cell Significance Index: -1.7400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0682
    Cell Significance Index: -9.9100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0724
    Cell Significance Index: -4.6700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0725
    Cell Significance Index: -9.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0764
    Cell Significance Index: -1.9100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0803
    Cell Significance Index: -4.9300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0862
    Cell Significance Index: -4.0500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1010
    Cell Significance Index: -1.2600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.1025
    Cell Significance Index: -3.0100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1029
    Cell Significance Index: -10.7100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1117
    Cell Significance Index: -1.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1180
    Cell Significance Index: -6.2000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1213
    Cell Significance Index: -9.0400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1223
    Cell Significance Index: -5.7000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1240
    Cell Significance Index: -8.7700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1251
    Cell Significance Index: -9.9100
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.1399
    Cell Significance Index: -0.8300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1597
    Cell Significance Index: -8.3200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1616
    Cell Significance Index: -2.0400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1624
    Cell Significance Index: -4.4200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1635
    Cell Significance Index: -3.4700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1635
    Cell Significance Index: -4.5700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1669
    Cell Significance Index: -5.8000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1779
    Cell Significance Index: -11.9600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2020
    Cell Significance Index: -5.7900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2123
    Cell Significance Index: -1.9600
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2132
    Cell Significance Index: -3.9400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.2157
    Cell Significance Index: -3.4600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.2233
    Cell Significance Index: -4.6600
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2249
    Cell Significance Index: -4.8600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2256
    Cell Significance Index: -9.8100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2257
    Cell Significance Index: -3.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2280
    Cell Significance Index: -7.4700
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2326
    Cell Significance Index: -4.6700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2372
    Cell Significance Index: -8.3100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2397
    Cell Significance Index: -6.4000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2407
    Cell Significance Index: -7.6700
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.2440
    Cell Significance Index: -3.5100
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2491
    Cell Significance Index: -3.5700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2492
    Cell Significance Index: -4.1700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SCLY is a member of the lyase family of enzymes, which catalyze the cleavage of various substrates to produce different products. In the context of selenocysteine metabolism, SCLY is responsible for the degradation of selenocysteine, a process essential for maintaining the balance of selenium within the cell. The enzyme exhibits homodimerization activity, suggesting its ability to interact with other proteins to regulate its activity. **Pathways and Functions** The SCLY gene is involved in various cellular pathways, including amino acid metabolism, selenocysteine catabolic process, and selenoamino acid metabolism. The enzyme's primary function is to cleave selenocysteine, a process that is crucial for regulating the levels of selenium within the cell. This process involves the conversion of selenocysteine into a less reactive form, thereby preventing oxidative damage to cellular components. The SCLY gene is also involved in the regulation of protein binding and homodimerization, which are essential processes for maintaining protein-protein interactions within the cell. The enzyme's ability to bind to amino acids and vitamins, such as vitamin B6, further highlights its importance in regulating cellular metabolism. **Clinical Significance** Dysregulation of SCLY expression has been implicated in various diseases, including cancer and cardiovascular diseases. For example, studies have shown that SCLY expression is elevated in certain types of cancer, suggesting its potential role as a tumor suppressor. Additionally, SCLY deficiency has been linked to cardiovascular diseases, highlighting the enzyme's importance in maintaining cardiovascular health. Furthermore, SCLY has been identified as a potential therapeutic target for the treatment of various diseases, including neurodegenerative disorders and metabolic disorders. The enzyme's ability to regulate selenium levels within the cell makes it an attractive target for the development of novel therapeutic agents. In conclusion, SCLY is a critical enzyme involved in the metabolism of selenocysteine, a process essential for maintaining cellular homeostasis. Its dysregulation has been implicated in various diseases, highlighting its potential as a therapeutic target. Further research is needed to fully elucidate the role of SCLY in human health and disease. **References** 1. [Insert references to relevant studies on SCLY expression and function] 2. [Insert references to studies on the clinical significance of SCLY in various diseases] **Future Directions** 1. Further investigation into the regulation of SCLY expression and its role in disease. 2. Development of novel therapeutic agents targeting SCLY for the treatment of various diseases. 3. Elucidation of the molecular mechanisms underlying SCLY's role in regulating selenocysteine metabolism. By continuing to explore the role of SCLY in human health and disease, we can uncover new insights into the regulation of cellular metabolism and develop novel therapeutic strategies for the treatment of various diseases.

Genular Protein ID: 3807204323

Symbol: SCLY_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q96I15 B9A068 J3KN06 Q53SN1 Q53SN8 Q7L670 Q9NVT7 Q9NZR7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 7 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 3 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIRSF 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10692412

Title: cDNA cloning, purification, and characterization of mouse liver selenocysteine lyase. Candidate for selenium delivery protein in selenoprotein synthesis.

PubMed ID: 10692412

DOI: 10.1074/jbc.275.9.6195

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16874457

Title: Enhanced expression of selenocysteine lyase in acute glomerulonephritis and its regulation by AP-1.

PubMed ID: 16874457

DOI: 10.2478/s11658-006-0035-1

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 445
  • Mass: 48149
  • Checksum: D26F3FCFB8B165D2
  • Sequence:
    • MEAAVAPGRD APAPAASQPS GCGKHNSPER KVYMDYNATT PLEPEVIQAM TKAMWEAWGN 
PSSPYSAGRK AKDIINAARE SLAKMIGGKP QDIIFTSGGT ESNNLVIHSV VKHFHANQTS 
KGHTGGHHSP VKGAKPHFIT SSVEHDSIRL PLEHLVEEQV AAVTFVPVSK VSGQAEVDDI 
LAAVRPTTRL VTIMLANNET GIVMPVPEIS QRIKALNQER VAAGLPPILV HTDAAQALGK 
QRVDVEDLGV DFLTIVGHKF YGPRIGALYI RGLGEFTPLY PMLFGGGQER NFRPGTENTP 
MIAGLGKAAE LVTQNCEAYE AHMRDVRDYL EERLEAEFGQ KRIHLNSQFP GTQRLPNTCN 
FSIRGPRLQG HVVLAQCRVL MASVGAACHS DHGDQPSPVL LSYGVPFDVA RNALRLSVGR 
STTRAEVDLV VQDLKQAVAQ LEDQA

Genular Protein ID: 49806748

Symbol: B4DDP9_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DDP9

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 2 Gene3D 3 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 412
  • Mass: 44816
  • Checksum: 2950E01542093867
  • Sequence:
    • MDYNATTPLE PEVIQAMTKA MWEAWGNPSS PYSAGRKAKD IINAARESLA KMIGGKPQDI 
IFTSGGTESN NLVIHSVVKH FHANQTSKGH TGGHHSPVKG AKPHFITSSV EHDSIRLPLE 
HLVEEQVAAV TFVPVSKVSG QAEVDDILAA VRPTTRLVTI MLANNETGIV MPVPEISQRI 
KALNQERVAA GLPPILVHTD AAQALGKQRV DVEDLGVDFL TIVGHKFYGP RIGALYIRGL 
GEFTPLYPML FGGGQERNFR PGTENTPMIA GLGKAAELVT QNCEAYEAHM RDVRDYLEER 
LEAEFGQKRI HLNSQFPGTQ RLPNTCNFSI RGPRLQGHVV LAQCRVLMAS VGAACHSDHG 
DQPSPVLLSY GVPFDVARNA LRLSVGRSTT RAEVDLVVQD LKQAVAQLED QA

Genular Protein ID: 533550191

Symbol: A0A0A0MQU4_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0A0MQU4

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 3 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 5 KEGG 1 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PeptideAtlas 2 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 453
  • Mass: 48793
  • Checksum: AF99FBFDAD4A5AE1
  • Sequence:
    • MPGSSGAGME AAVAPGRDAP APAASQPSGC GKHNSPERKV YMDYNATTPL EPEVIQAMTK 
AMWEAWGNPS SPYSAGRKAK DIINAARESL AKMIGGKPQD IIFTSGGTES NNLVIHSVVK 
HFHANQTSKG HTGGHHSPVK GAKPHFITSS VEHDSIRLPL EHLVEEQVAA VTFVPVSKVS 
GQAEVDDILA AVRPTTRLVT IMLANNETGI VMPVPEISQR IKALNQERVA AGLPPILVHT 
DAAQALGKQR VDVEDLGVDF LTIVGHKFYG PRIGALYIRG LGEFTPLYPM LFGGGQERNF 
RPGTENTPMI AGLGKAAELV TQNCEAYEAH MRDVRDYLEE RLEAEFGQKR IHLNSQFPGT 
QRLPNTCNFS IRGPRLQGHV VLAQCRVLMA SVGAACHSDH GDQPSPVLLS YGVPFDVARN 
ALRLSVGRST TRAEVDLVVQ DLKQAVAQLE DQA

Genular Protein ID: 17156369

Symbol: Q59FK2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q59FK2

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMR 1 SUPFAM 1

Sequence Information:

  • Length: 235
  • Mass: 25485
  • Checksum: 0D6AAD62294828CC
  • Sequence:
    • FSNPFCGETF PRKPDLKGTH RWAPQPSEGG QAPFHYFLGG TRLHPAAPGA PGGRTSGSLL 
NVKMMKMKTF MMICFHLINT VTFVPVSKVS GQTEVDDILA AVRPTTRLVT IMLANNETGI 
VMPVPEISQR IKALNQERVA AGLPPILVHT DAAQALGKQR VDVEDLGVDF LTIVGHKFYG 
PRIGALYIRG LGEFTPLYPM LFGGGQERNF RPGTENTPMI AGLGKVSPGE LEEMS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.