Details for: CDK5RAP1

Gene ID: 51654

Symbol: CDK5RAP1

Ensembl ID: ENSG00000101391

Description: CDK5 regulatory subunit associated protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 152.0458
    Cell Significance Index: -23.6500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 94.4633
    Cell Significance Index: -23.9600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 56.8113
    Cell Significance Index: -23.0800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 56.8073
    Cell Significance Index: -26.8200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 24.3102
    Cell Significance Index: -23.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 21.1281
    Cell Significance Index: -26.0500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.0860
    Cell Significance Index: -24.3400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 6.7257
    Cell Significance Index: -26.5400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.7924
    Cell Significance Index: -8.3000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.4252
    Cell Significance Index: 285.8900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0012
    Cell Significance Index: 198.6900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.9903
    Cell Significance Index: 894.1700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.7725
    Cell Significance Index: 10.5400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7702
    Cell Significance Index: 83.7800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7339
    Cell Significance Index: 32.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.7332
    Cell Significance Index: 44.0200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.7246
    Cell Significance Index: 27.4400
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6871
    Cell Significance Index: 111.7500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.6470
    Cell Significance Index: 40.7800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.5836
    Cell Significance Index: 68.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5455
    Cell Significance Index: 195.6700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.5417
    Cell Significance Index: 15.1400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4936
    Cell Significance Index: 33.1900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4464
    Cell Significance Index: 308.7600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4337
    Cell Significance Index: 33.2800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.3953
    Cell Significance Index: 10.1600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3443
    Cell Significance Index: 23.8100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2682
    Cell Significance Index: 5.8100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2551
    Cell Significance Index: 45.9800
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2436
    Cell Significance Index: 6.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2336
    Cell Significance Index: 6.7300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2289
    Cell Significance Index: 28.1400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2143
    Cell Significance Index: 117.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2092
    Cell Significance Index: 13.5000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1964
    Cell Significance Index: 10.2000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1939
    Cell Significance Index: 9.0400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.1921
    Cell Significance Index: 2.2900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1878
    Cell Significance Index: 83.0400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1746
    Cell Significance Index: 20.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.1298
    Cell Significance Index: 17.8300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1050
    Cell Significance Index: 5.8900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0793
    Cell Significance Index: 149.2700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0790
    Cell Significance Index: 3.5800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0469
    Cell Significance Index: 6.0100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0413
    Cell Significance Index: 1.9400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0357
    Cell Significance Index: 3.5300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0355
    Cell Significance Index: 6.0600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0317
    Cell Significance Index: 20.1100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0313
    Cell Significance Index: 1.1000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0305
    Cell Significance Index: 3.9500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0281
    Cell Significance Index: 51.7700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0249
    Cell Significance Index: 1.5300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0237
    Cell Significance Index: 0.7600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0181
    Cell Significance Index: 8.2100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0149
    Cell Significance Index: 23.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0085
    Cell Significance Index: 11.5700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0046
    Cell Significance Index: 0.8800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0030
    Cell Significance Index: -0.0800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0102
    Cell Significance Index: -0.1700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0111
    Cell Significance Index: -6.9100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0112
    Cell Significance Index: -8.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0207
    Cell Significance Index: -15.2000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0225
    Cell Significance Index: -3.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0260
    Cell Significance Index: -19.7200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0312
    Cell Significance Index: -17.6100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0341
    Cell Significance Index: -0.5900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0361
    Cell Significance Index: -0.7900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0379
    Cell Significance Index: -2.6800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0576
    Cell Significance Index: -5.8800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0594
    Cell Significance Index: -4.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0759
    Cell Significance Index: -15.9800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0810
    Cell Significance Index: -23.3100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0939
    Cell Significance Index: -2.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1058
    Cell Significance Index: -12.1200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1202
    Cell Significance Index: -6.3100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1217
    Cell Significance Index: -6.3400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1730
    Cell Significance Index: -6.0100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1955
    Cell Significance Index: -5.2300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2213
    Cell Significance Index: -25.2600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2229
    Cell Significance Index: -23.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2428
    Cell Significance Index: -5.1700
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2583
    Cell Significance Index: -7.5900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2704
    Cell Significance Index: -7.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2849
    Cell Significance Index: -7.6400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2870
    Cell Significance Index: -22.7300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3245
    Cell Significance Index: -19.9000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.3412
    Cell Significance Index: -6.6600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3725
    Cell Significance Index: -5.5000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4019
    Cell Significance Index: -12.8000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4040
    Cell Significance Index: -8.6400
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4136
    Cell Significance Index: -5.1300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4138
    Cell Significance Index: -10.5700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4225
    Cell Significance Index: -11.1100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4433
    Cell Significance Index: -9.2800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.4466
    Cell Significance Index: -10.7100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4528
    Cell Significance Index: -14.8300
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4598
    Cell Significance Index: -11.2200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4693
    Cell Significance Index: -9.9600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4954
    Cell Significance Index: -7.4700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5406
    Cell Significance Index: -18.9400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CDK5RAP1 is a protein that interacts with cyclin-dependent kinase 5 (CDK5), a protein kinase involved in various cellular processes, including cell cycle progression and neuronal differentiation. CDK5RAP1 is a regulatory subunit that interacts with CDK5, modulating its activity and influencing the downstream signaling pathways. The gene is highly expressed in cells of the immune system, including hematopoietic cells, mast cells, and T cells, suggesting its involvement in immune cell development and function. **Pathways and Functions** CDK5RAP1 is implicated in several signaling pathways, including: 1. **Mitochondrial translation regulation**: CDK5RAP1 is involved in the regulation of mitochondrial translation, a process crucial for energy production and cellular metabolism. 2. **Trna methylthiolation**: CDK5RAP1 interacts with enzymes involved in trna methylthiolation, a process that regulates trna modification and translation fidelity. 3. **Regulation of cyclin-dependent protein serine/threonine kinase activity**: CDK5RAP1 modulates the activity of cyclin-dependent kinases, influencing cell cycle progression and cellular differentiation. 4. **Brain development and neuronal differentiation**: CDK5RAP1 is involved in the regulation of neuronal differentiation and development, highlighting its role in neuroimmunology. **Clinical Significance** CDK5RAP1's involvement in immune cell development and function has significant implications for the diagnosis and treatment of various diseases. For instance: 1. **Immunodeficiency disorders**: CDK5RAP1's role in hematopoietic cell development and function may contribute to the pathogenesis of immunodeficiency disorders, such as leukemia and lymphoma. 2. **Neurological disorders**: CDK5RAP1's involvement in neuronal differentiation and development may be linked to neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer research**: CDK5RAP1's role in cell cycle progression and translation regulation may be exploited in cancer research, providing new targets for therapeutic intervention. In conclusion, CDK5RAP1 is a complex gene that plays a multifaceted role in cellular biology and immunology. Further research is needed to fully understand its functions and implications in human disease. As an expert immunologist, it is crucial to continue exploring the intricacies of CDK5RAP1, shedding light on its potential applications in the diagnosis and treatment of various diseases.

Genular Protein ID: 504815749

Symbol: CK5P1_HUMAN

Name: CDK5 activator-binding protein C42

UniProtKB Accession Codes:

Q96SZ6 A8K7R0 Q5QP46 Q5QP47 Q5QP48 Q675N4 Q675N5 Q9BVG6 Q9BWZ5 Q9H859 Q9NZZ9 Q9Y3F0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CTD 1 ChEBI 18 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 13 Ensembl 4 ExpressionAtlas 1 GO 13 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 2 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 4 Rhea 6 SFLD 4 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10810093

Title: Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics.

PubMed ID: 10810093

DOI: 10.1101/gr.10.5.703

PubMed ID: 11042152

Title: Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.

PubMed ID: 11042152

DOI: 10.1101/gr.140200

PubMed ID: 15329498

Title: Cloning, characterization and expression of CDK5RAP1_v3 and CDK5RAP1_v4, two novel splice variants of human CDK5RAP1.

PubMed ID: 15329498

DOI: 10.1266/ggs.79.177

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 11780052

Title: The DNA sequence and comparative analysis of human chromosome 20.

PubMed ID: 11780052

DOI: 10.1038/414865a

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10721722

Title: Cloning of three novel neuronal Cdk5 activator binding proteins.

PubMed ID: 10721722

DOI: 10.1016/s0378-1119(99)00499-0

PubMed ID: 11882646

Title: Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor.

PubMed ID: 11882646

DOI: 10.1074/jbc.c200032200

PubMed ID: 22422838

Title: The CDK5 repressor CDK5RAP1 is a methylthiotransferase acting on nuclear and mitochondrial RNA.

PubMed ID: 22422838

DOI: 10.1093/nar/gks240

PubMed ID: 25738458

Title: Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans.

PubMed ID: 25738458

DOI: 10.1016/j.cmet.2015.01.019

PubMed ID: 28981754

Title: Cdk5rap1-mediated 2-methylthio-N6-isopentenyladenosine modification is absent from nuclear-derived RNA species.

PubMed ID: 28981754

DOI: 10.1093/nar/gkx819

Sequence Information:

  • Length: 601
  • Mass: 67689
  • Checksum: 4AEBFD7DA5400902
  • Sequence:
    • MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 
AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 
SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 
LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 
VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQVFLPPRPP 
KVLGLQGLKE VTLLGQNVNS FRDNSEVQFN SAVPTNLSRG FTTNYKTKQG GLRFAHLLDQ 
VSRVDPEMRI RFTSPHPKDF PDEVLQLIHE RDNICKQIHL PAQSGSSRVL EAMRRGYSRE 
AYVELVHHIR ESIPGVSLSS DFIAGFCGET EEDHVQTVSL LREVQYNMGF LFAYSMRQKT 
RAYHRLKDDV PEEVKLRRLE ELITIFREEA TKANQTSVGC TQLVLVEGLS KRSATDLCGR 
NDGNLKVIFP DAEMEDVNNP GLRVRAQPGD YVLVKITSAS SQTLRGHVLC RTTLRDSSAY 
C

Genular Protein ID: 3984021351

Symbol: Q53H36_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53H36

Database IDs:

ARBA 7 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 HAMAP 1 InterPro 9 NCBI Taxonomy 1 NCBIfam 2 OrthoDB 1 PANTHER 2 PROSITE 7 PeptideAtlas 1 Pfam 3 RefSeq 1 SFLD 4 SMART 1 SUPFAM 1

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 586
  • Mass: 66017
  • Checksum: 62C970660EE28BD9
  • Sequence:
    • MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 
AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 
SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 
LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 
VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQGLKEVTLL 
GQNVNSFRDN SEVQFNSAVP TNLSRGFTTN YKTKQGGLRF AHLLDQVSRV DPEMRIRFTS 
PHPKDFPDEV LQLIHERDNI CKQIHLPAQS GSSRVLEAMR RGYSREAYVE LVHHIRESIP 
GVSLSSDFIA GFCGETEEDH VQTVSLLREV QYNMGFLFAY SMRQTRAYHR LKDDVPEEVK 
LRRLEELITI FREEATKANQ TSVGCTQLVL VEGLSKRSAT DLCGRNDGNL KVIFPDAEME 
DVNNPGLRVR AQPGDYVLVK ITSASSQTLR GHVLCRTTLR DSSAYC

Genular Protein ID: 1273560564

Symbol: A0A0S2Z5J9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z5J9

Database IDs:

ARBA 7 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 9 Gene3D 2 HAMAP 1 InterPro 9 NCBI Taxonomy 1 NCBIfam 2 OrthoDB 1 PANTHER 2 PROSITE 7 Pfam 3 RefSeq 1 SFLD 4 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 587
  • Mass: 66146
  • Checksum: 314E826B35C346EB
  • Sequence:
    • MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 
AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 
SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 
LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 
VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQGLKEVTLL 
GQNVNSFRDN SEVQFNSAVP TNLSRGFTTN YKTKQGGLRF AHLLDQVSRV DPEMRIRFTS 
PHPKDFPDEV LQLIHERDNI CKQIHLPAQS GSSRVLEAMR RGYSREAYVE LVHHIRESIP 
GVSLSSDFIA GFCGETEEDH VQTVSLLREV QYNMGFLFAY SMRQKTRAYH RLKDDVPEEV 
KLRRLEELIT IFREEATKAN QTSVGCTQLV LVEGLSKRSA TDLCGRNDGN LKVIFPDAEM 
EDVNNPGLRV RAQPGDYVLV KITSASSQTL RGHVLCRTTL RDSSAYC

Genular Protein ID: 813967881

Symbol: A0A0S2Z592_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z592

Database IDs:

ARBA 6 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 ExpressionAtlas 1 GO 6 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 7 Pfam 3 RefSeq 1 SFLD 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 510
  • Mass: 57413
  • Checksum: 8F0DFB3B71E135BB
  • Sequence:
    • MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 
AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 
SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 
LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 
VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQVLQLIHER 
DNICKQIHLP AQSGSSRVLE AMRRGYSREA YVELVHHIRE SIPGVSLSSD FIAGFCGETE 
EDHVQTVSLL REVQYNMGFL FAYSMRQKTR AYHRLKDDVP EEVKLRRLEE LITIFREEAT 
KANQTSVGCT QLVLVEGLSK RSATDLCGRN DGNLKVIFPD AEMEDVNNPG LRVRAQPGDY 
VLVKITSASS QTLRGHVLCR TTLRDSSAYC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.