Details for: KDM3B

Gene ID: 51780

Symbol: KDM3B

Ensembl ID: ENSG00000120733

Description: lysine demethylase 3B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 268.9893
    Cell Significance Index: -41.8400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 166.4542
    Cell Significance Index: -42.2200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 97.7066
    Cell Significance Index: -40.2500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 95.0177
    Cell Significance Index: -44.8600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 90.4600
    Cell Significance Index: -36.7500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 81.6509
    Cell Significance Index: -42.0000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 38.5444
    Cell Significance Index: -36.8000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.3297
    Cell Significance Index: -43.5600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.9434
    Cell Significance Index: -42.7100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 12.4258
    Cell Significance Index: -27.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 11.1732
    Cell Significance Index: -44.0900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.6279
    Cell Significance Index: 22.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.5940
    Cell Significance Index: 319.7600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5357
    Cell Significance Index: 304.7600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.4829
    Cell Significance Index: 83.2100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.2077
    Cell Significance Index: 131.3700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1807
    Cell Significance Index: 192.0400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.0993
    Cell Significance Index: 27.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9682
    Cell Significance Index: 74.3000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.9607
    Cell Significance Index: 57.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.8797
    Cell Significance Index: 315.5400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.8538
    Cell Significance Index: 23.8600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.8111
    Cell Significance Index: 15.8300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6003
    Cell Significance Index: 41.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5560
    Cell Significance Index: 16.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.5408
    Cell Significance Index: 28.1700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5053
    Cell Significance Index: 22.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4714
    Cell Significance Index: 84.9700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.4559
    Cell Significance Index: 11.7200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4324
    Cell Significance Index: 16.3800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.4122
    Cell Significance Index: 285.0600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3996
    Cell Significance Index: 49.1400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3729
    Cell Significance Index: 23.5100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3434
    Cell Significance Index: 21.1100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.3226
    Cell Significance Index: 21.6900
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2923
    Cell Significance Index: 13.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2796
    Cell Significance Index: 152.7100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2384
    Cell Significance Index: 45.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2037
    Cell Significance Index: 27.9700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1616
    Cell Significance Index: 4.3300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1594
    Cell Significance Index: 300.0700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1421
    Cell Significance Index: 62.8400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1033
    Cell Significance Index: 3.6300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0939
    Cell Significance Index: 1.6100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0827
    Cell Significance Index: 127.3200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0802
    Cell Significance Index: 36.3900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0800
    Cell Significance Index: 50.8200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0796
    Cell Significance Index: 146.7300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0795
    Cell Significance Index: 7.8600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0570
    Cell Significance Index: 2.9600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0454
    Cell Significance Index: 61.7100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0424
    Cell Significance Index: 2.7400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0397
    Cell Significance Index: 1.8500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0052
    Cell Significance Index: -0.1400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0062
    Cell Significance Index: -0.1400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0114
    Cell Significance Index: -1.6600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0317
    Cell Significance Index: -23.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0387
    Cell Significance Index: -6.6000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0401
    Cell Significance Index: -4.7300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0409
    Cell Significance Index: -30.2900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0464
    Cell Significance Index: -35.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0468
    Cell Significance Index: -6.0000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0727
    Cell Significance Index: -41.0000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0759
    Cell Significance Index: -47.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0913
    Cell Significance Index: -4.2900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1139
    Cell Significance Index: -11.6300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.1201
    Cell Significance Index: -1.7200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1319
    Cell Significance Index: -37.9600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1342
    Cell Significance Index: -15.6400
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.2057
    Cell Significance Index: -5.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2116
    Cell Significance Index: -27.3400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2143
    Cell Significance Index: -4.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2203
    Cell Significance Index: -46.4100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2262
    Cell Significance Index: -3.3400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2364
    Cell Significance Index: -5.6700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2417
    Cell Significance Index: -27.6900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2834
    Cell Significance Index: -20.0400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2835
    Cell Significance Index: -3.3800
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2861
    Cell Significance Index: -6.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3113
    Cell Significance Index: -32.4200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3323
    Cell Significance Index: -24.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3381
    Cell Significance Index: -8.8900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3777
    Cell Significance Index: -3.0800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.4087
    Cell Significance Index: -8.9500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.4366
    Cell Significance Index: -5.4200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4390
    Cell Significance Index: -14.0600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4640
    Cell Significance Index: -36.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.4859
    Cell Significance Index: -13.2300
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.5069
    Cell Significance Index: -7.2900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5264
    Cell Significance Index: -27.6400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.5800
    Cell Significance Index: -20.1600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.5877
    Cell Significance Index: -16.7700
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.6118
    Cell Significance Index: -9.2200
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.6523
    Cell Significance Index: -6.5800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.6610
    Cell Significance Index: -14.0300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7105
    Cell Significance Index: -43.5600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.7188
    Cell Significance Index: -12.0300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7407
    Cell Significance Index: -23.5900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.7547
    Cell Significance Index: -6.9500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7598
    Cell Significance Index: -24.8800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** KDM3B is a lysine demethylase that specifically demethylates histone H3K9, leading to the removal of methyl groups from lysine residues. This process is crucial for chromatin remodeling and transcriptional regulation. KDM3B is characterized by its ability to bind metal ions, such as zinc and iron, which are essential for its catalytic activity. The enzyme is also involved in the regulation of transcription by RNA polymerase II and acts as a transcriptional coregulator. **Pathways and Functions:** KDM3B is involved in several key pathways, including: 1. **Antioxidant activity:** KDM3B has been implicated in the regulation of antioxidant enzymes, such as glutathione peroxidase, which is essential for maintaining cellular redox balance. 2. **Cellular oxidant detoxification:** KDM3B plays a role in the removal of reactive oxygen species (ROS) from the cell, which is critical for maintaining cellular homeostasis. 3. **Chromatin organization:** KDM3B is involved in the regulation of chromatin structure and organization, which is essential for gene expression and cellular differentiation. 4. **Histone H3K9 demethylase activity:** KDM3B specifically demethylates histone H3K9, leading to the removal of methyl groups and chromatin remodeling. 5. **Metal ion binding:** KDM3B binds metal ions, such as zinc and iron, which are essential for its catalytic activity. **Clinical Significance:** Recent studies have highlighted the clinical significance of KDM3B in various diseases, including: 1. **Cancer:** KDM3B has been implicated in the regulation of cancer cell growth and survival. Overexpression of KDM3B has been observed in various types of cancer, including breast, lung, and colon cancer. 2. **Autoimmune diseases:** KDM3B has been implicated in the regulation of immune responses and has been shown to play a role in the development of autoimmune diseases, such as rheumatoid arthritis. 3. **Neurological disorders:** KDM3B has been implicated in the regulation of neuronal function and has been shown to play a role in the development of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, KDM3B is a key player in histone demethylation and epigenetic regulation, and its dysregulation has been implicated in various diseases. Further studies are needed to fully understand the functional significance of KDM3B and its potential as a therapeutic target in disease prevention and treatment.

Genular Protein ID: 2042928557

Symbol: KDM3B_HUMAN

Name: Lysine-specific demethylase 3B

UniProtKB Accession Codes:

Q7LBC6 A6H8X7 Q9BVH6 Q9BW93 Q9BZ52 Q9NYF4 Q9UPS0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 11 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 36 PDBsum 36 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11087669

Title: cDNA cloning and genomic structure of three genes localized to human chromosome band 5q31 encoding potential nuclear proteins.

PubMed ID: 11087669

DOI: 10.1006/geno.2000.6345

PubMed ID: 11687974

Title: A novel nuclear protein, 5qNCA (LOC51780) is a candidate for the myeloid leukemia tumor suppressor gene on chromosome 5 band q31.

PubMed ID: 11687974

DOI: 10.1038/sj.onc.1204850

PubMed ID: 10470851

Title: Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10470851

DOI: 10.1093/dnares/6.3.197

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16603237

Title: JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptor.

PubMed ID: 16603237

DOI: 10.1016/j.cell.2006.03.027

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30929739

Title: De Novo and Inherited Pathogenic Variants in KDM3B Cause Intellectual Disability, Short Stature, and Facial Dysmorphism.

PubMed ID: 30929739

DOI: 10.1016/j.ajhg.2019.02.023

Sequence Information:

  • Length: 1761
  • Mass: 191581
  • Checksum: FB900FCBF0675CD8
  • Sequence:
    • MADAAASPVG KRLLLLFADT AASASASAPA AAAASGDPGP ALRTRAWRAG TVRAMSGAVP 
QDLAIFVEFD GCNWKQHSWV KVHAEEVIVL LLEGSLVWAP REDPVLLQGI RVSIAQWPAL 
TFTPLVDKLG LGSVVPVEYL LDRELRFLSD ANGLHLFQMG TDSQNQILLE HAALRETVNA 
LISDQKLQEI FSRGPYSVQG HRVKIYQPEG EEGWLYGVVS HQDSITRLME VSVTESGEIK 
SVDPRLIHVM LMDNSAPQSE GGTLKAVKSS KGKKKRESIE GKDGRRRKSA SDSGCDPASK 
KLKGDRGEVD SNGSDGGEAS RGPWKGGNAS GEPGLDQRAK QPPSTFVPQI NRNIRFATYT 
KENGRTLVVQ DEPVGGDTPA SFTPYSTATG QTPLAPEVGG AENKEAGKTL EQVGQGIVAS 
AAVVTTASST PNTVRISDTG LAAGTVPEKQ KGSRSQASGE NSRNSILASS GFGAPLPSSS 
QPLTFGSGRS QSNGVLATEN KPLGFSFGCS SAQEAQKDTD LSKNLFFQCM SQTLPTSNYF 
TTVSESLADD SSSRDSFKQS LESLSSGLCK GRSVLGTDTK PGSKAGSSVD RKVPAESMPT 
LTPAFPRSLL NARTPENHEN LFLQPPKLSR EEPSNPFLAF VEKVEHSPFS SFASQASGSS 
SSATTVTSKV APSWPESHSS ADSASLAKKK PLFITTDSSK LVSGVLGSAL TSGGPSLSAM 
GNGRSSSPTS SLTQPIEMPT LSSSPTEERP TVGPGQQDNP LLKTFSNVFG RHSGGFLSSP 
ADFSQENKAP FEAVKRFSLD ERSLACRQDS DSSTNSDLSD LSDSEEQLQA KTGLKGIPEH 
LMGKLGPNGE RSAELLLGKS KGKQAPKGRP RTAPLKVGQS VLKDVSKVKK LKQSGEPFLQ 
DGSCINVAPH LHKCRECRLE RYRKFKEQEQ DDSTVACRFF HFRRLIFTRK GVLRVEGFLS 
PQQSDPDAMN LWIPSSSLAE GIDLETSKYI LANVGDQFCQ LVMSEKEAMM MVEPHQKVAW 
KRAVRGVREM CDVCETTLFN IHWVCRKCGF GVCLDCYRLR KSRPRSETEE MGDEEVFSWL 
KCAKGQSHEP ENLMPTQIIP GTALYNIGDM VHAARGKWGI KANCPCISRQ NKSVLRPAVT 
NGMSQLPSIN PSASSGNETT FSGGGGPAPV TTPEPDHVPK ADSTDIRSEE PLKTDSSASN 
SNSELKAIRP PCPDTAPPSS ALHWLADLAT QKAKEETKEA GSLRSVLNKE SHSPFGLDSF 
NSTAKVSPLT PKLFNSLLLG PTASNNKTEG SSLRDLLHSG PGKLPQTPLD TGIPFPPVFS 
TSSAGVKSKA SLPNFLDHII ASVVENKKTS DASKRACNLT DTQKEVKEMV MGLNVLDPHT 
SHSWLCDGRL LCLHDPSNKN NWKIFRECWK QGQPVLVSGV HKKLKSELWK PEAFSQEFGD 
QDVDLVNCRN CAIISDVKVR DFWDGFEIIC KRLRSEDGQP MVLKLKDWPP GEDFRDMMPT 
RFEDLMENLP LPEYTKRDGR LNLASRLPSY FVRPDLGPKM YNAYGLITAE DRRVGTTNLH 
LDVSDAVNVM VYVGIPIGEG AHDEEVLKTI DEGDADEVTK QRIHDGKEKP GALWHIYAAK 
DAEKIRELLR KVGEEQGQEN PPDHDPIHDQ SWYLDQTLRK RLYEEYGVQG WAIVQFLGDA 
VFIPAGAPHQ VHNLYSCIKV AEDFVSPEHV KHCFRLTQEF RHLSNTHTNH EDKLQVKNII 
YHAVKDAVGT LKAHESKLAR S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.