Details for: PFAS

Gene ID: 5198

Symbol: PFAS

Ensembl ID: ENSG00000178921

Description: phosphoribosylformylglycinamidine synthase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 64.9972
    Cell Significance Index: -10.1100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 38.6763
    Cell Significance Index: -9.8100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 8.6053
    Cell Significance Index: -10.6100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.0428
    Cell Significance Index: -10.8300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.7420
    Cell Significance Index: -10.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.1410
    Cell Significance Index: 217.1400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5297
    Cell Significance Index: 478.3000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5272
    Cell Significance Index: 31.6500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5240
    Cell Significance Index: 56.9900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.4666
    Cell Significance Index: 75.8900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4294
    Cell Significance Index: 85.2200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3715
    Cell Significance Index: 10.7100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2993
    Cell Significance Index: 18.8700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.2573
    Cell Significance Index: 3.5100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2483
    Cell Significance Index: 17.1700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2369
    Cell Significance Index: 6.6200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2292
    Cell Significance Index: 22.6700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1901
    Cell Significance Index: 38.1300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1625
    Cell Significance Index: 3.5200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1497
    Cell Significance Index: 4.0100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1461
    Cell Significance Index: 9.4300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1363
    Cell Significance Index: 6.1800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1351
    Cell Significance Index: 24.3500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1157
    Cell Significance Index: 6.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1006
    Cell Significance Index: 36.0900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0780
    Cell Significance Index: 1.9500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0760
    Cell Significance Index: 4.2700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0756
    Cell Significance Index: 1.6100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0728
    Cell Significance Index: 8.5900
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.0727
    Cell Significance Index: 0.7900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0689
    Cell Significance Index: 47.6600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0621
    Cell Significance Index: 33.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0505
    Cell Significance Index: 22.3300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0401
    Cell Significance Index: 2.0900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0401
    Cell Significance Index: 1.4100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0400
    Cell Significance Index: 4.9200
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0389
    Cell Significance Index: 2.7500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0257
    Cell Significance Index: 3.5300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0106
    Cell Significance Index: 0.2200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0072
    Cell Significance Index: 0.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0014
    Cell Significance Index: 2.6900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0013
    Cell Significance Index: 0.0600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0003
    Cell Significance Index: 0.0200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0021
    Cell Significance Index: -0.2700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0047
    Cell Significance Index: -8.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0068
    Cell Significance Index: -10.4700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0079
    Cell Significance Index: -5.0100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0086
    Cell Significance Index: -6.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0096
    Cell Significance Index: -13.0600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0099
    Cell Significance Index: -7.5200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0163
    Cell Significance Index: -7.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0173
    Cell Significance Index: -12.7900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0180
    Cell Significance Index: -0.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0219
    Cell Significance Index: -1.6800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0225
    Cell Significance Index: -12.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0282
    Cell Significance Index: -8.1200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0284
    Cell Significance Index: -1.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0309
    Cell Significance Index: -0.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0330
    Cell Significance Index: -5.6400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0391
    Cell Significance Index: -5.6800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0421
    Cell Significance Index: -5.4400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0435
    Cell Significance Index: -5.0700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0455
    Cell Significance Index: -4.6500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0519
    Cell Significance Index: -2.4400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0567
    Cell Significance Index: -0.9100
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0591
    Cell Significance Index: -1.5100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0628
    Cell Significance Index: -13.2400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0669
    Cell Significance Index: -1.7900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0672
    Cell Significance Index: -4.5200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0681
    Cell Significance Index: -1.7900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0699
    Cell Significance Index: -1.5300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0699
    Cell Significance Index: -8.0100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0750
    Cell Significance Index: -1.5700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0843
    Cell Significance Index: -3.7300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0853
    Cell Significance Index: -6.3600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0890
    Cell Significance Index: -1.4900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.0901
    Cell Significance Index: -1.3500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0982
    Cell Significance Index: -10.2300
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0994
    Cell Significance Index: -2.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1080
    Cell Significance Index: -4.0900
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1126
    Cell Significance Index: -1.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1149
    Cell Significance Index: -9.1000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1231
    Cell Significance Index: -2.1100
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1243
    Cell Significance Index: -1.7800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1294
    Cell Significance Index: -3.8100
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.1306
    Cell Significance Index: -1.1100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1354
    Cell Significance Index: -3.4800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1465
    Cell Significance Index: -2.8600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1794
    Cell Significance Index: -9.4200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1911
    Cell Significance Index: -2.8800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1985
    Cell Significance Index: -2.0600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2125
    Cell Significance Index: -1.4400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2192
    Cell Significance Index: -7.6800
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2240
    Cell Significance Index: -3.2100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2246
    Cell Significance Index: -11.3500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2258
    Cell Significance Index: -7.1900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2327
    Cell Significance Index: -7.6200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2525
    Cell Significance Index: -2.3300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.2639
    Cell Significance Index: -6.3300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.2642
    Cell Significance Index: -7.5400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PRF1A is a cytoplasmic enzyme that is highly expressed in germ cells, including spermatogonia and oocytes. It is also found in various tissues, including the brain, where it is involved in the regulation of purine metabolism. The gene has been implicated in several diseases, including certain types of cancer, where disruptions in purine metabolism can contribute to tumorigenesis. PRF1A is a member of the purine biosynthetic pathway, which is essential for the synthesis of purine nucleotides. The gene is closely related to other genes involved in purine metabolism, including PRF1B, PRF1C, and PRF1D. The protein product of PRF1A is a bifunctional enzyme that catalyzes the formation of PRF-G and the subsequent conversion of PRF-G to inosine monophosphate (IMP). **Pathways and Functions** PRF1A is involved in the following pathways: 1. **Purine biosynthetic process**: PRF1A is a key enzyme in the de novo synthesis of purines, which are essential components of DNA and RNA. 2. **GMP biosynthetic process**: PRF1A is involved in the conversion of PRF-G to GMP, a critical intermediate in the synthesis of purine nucleotides. 3. **Metabolism of nucleotides**: PRF1A is involved in the regulation of nucleotide metabolism, including the synthesis and degradation of purine nucleotides. PRF1A plays a critical role in maintaining the balance of purine nucleotides in the body. Disruptions in PRF1A function can lead to imbalances in purine metabolism, which can contribute to various diseases, including cancer. **Clinical Significance** Dysregulation of PRF1A has been implicated in several diseases, including: 1. **Cancer**: Disruptions in purine metabolism can contribute to tumorigenesis, and PRF1A has been found to be overexpressed in certain types of cancer, including leukemia and lymphoma. 2. **Neurological disorders**: PRF1A has been implicated in various neurological disorders, including Parkinson's disease, Alzheimer's disease, and Huntington's disease, where disruptions in purine metabolism can contribute to disease progression. 3. **Immunological disorders**: PRF1A has been found to be involved in the regulation of immune responses, and disruptions in PRF1A function can contribute to immunological disorders, including autoimmune diseases and immunodeficiency disorders. In conclusion, PRF1A is a critical gene involved in purine nucleotide biosynthesis, and its dysregulation has been implicated in various diseases. Further research is needed to fully understand the role of PRF1A in human health and disease.

Genular Protein ID: 2741604978

Symbol: PUR4_HUMAN

Name: Phosphoribosylformylglycinamidine synthase

UniProtKB Accession Codes:

O15067 A6H8V8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEBI 17 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 1 EMBL 4 Ensembl 1 ExpressionAtlas 1 GO 15 Gene3D 4 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HAMAP 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 5 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10548741

Title: Human phosphoribosylformylglycinamide amidotransferase (FGARAT): regional mapping, complete coding sequence, isolation of a functional genomic clone, and DNA sequence analysis.

PubMed ID: 10548741

DOI: 10.1016/s0378-1119(99)00378-9

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

Sequence Information:

  • Length: 1338
  • Mass: 144734
  • Checksum: 273405025B701DAF
  • Sequence:
    • MSPVLHFYVR PSGHEGAAPG HTRRKLQGKL PELQGVETEL CYNVNWTAEA LPSAEETKKL 
MWLFGCPLLL DDVARESWLL PGSNDLLLEV GPRLNFSTPT STNIVSVCRA TGLGPVDRVE 
TTRRYRLSFA HPPSAEVEAI ALATLHDRMT EQHFPHPIQS FSPESMPEPL NGPINILGEG 
RLALEKANQE LGLALDSWDL DFYTKRFQEL QRNPSTVEAF DLAQSNSEHS RHWFFKGQLH 
VDGQKLVHSL FESIMSTQES SNPNNVLKFC DNSSAIQGKE VRFLRPEDPT RPSRFQQQQG 
LRHVVFTAET HNFPTGVCPF SGATTGTGGR IRDVQCTGRG AHVVAGTAGY CFGNLHIPGY 
NLPWEDPSFQ YPGNFARPLE VAIEASNGAS DYGNKFGEPV LAGFARSLGL QLPDGQRREW 
IKPIMFSGGI GSMEADHISK EAPEPGMEVV KVGGPVYRIG VGGGAASSVQ VQGDNTSDLD 
FGAVQRGDPE MEQKMNRVIR ACVEAPKGNP ICSLHDQGAG GNGNVLKELS DPAGAIIYTS 
RFQLGDPTLN ALEIWGAEYQ ESNALLLRSP NRDFLTHVSA RERCPACFVG TITGDRRIVL 
VDDRECPVRR NGQGDAPPTP LPTPVDLELE WVLGKMPRKE FFLQRKPPML QPLALPPGLS 
VHQALERVLR LPAVASKRYL TNKVDRSVGG LVAQQQCVGP LQTPLADVAV VALSHEELIG 
AATALGEQPV KSLLDPKVAA RLAVAEALTN LVFALVTDLR DVKCSGNWMW AAKLPGEGAA 
LADACEAMVA VMAALGVAVD GGKDSLSMAA RVGTETVRAP GSLVISAYAV CPDITATVTP 
DLKHPEGRGH LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR AFSITQGLLK 
DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD VLSVLFAEEP GLVLEVQEPD 
LAQVLKRYRD AGLHCLELGH TGEAGPHAMV RVSVNGAVVL EEPVGELRAL WEETSFQLDR 
LQAEPRCVAE EERGLRERMG PSYCLPPTFP KASVPREPGG PSPRVAILRE EGSNGDREMA 
DAFHLAGFEV WDVTMQDLCS GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA AAVTFHPRAG 
AELRRFRKRP DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP GLLLRHNLSG 
RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF SSPELQAQIE ARGLAPLHWA 
DDDGNPTEQY PLNPNGSPGG VAGICSCDGR HLAVMPHPER AVRPWQWAWR PPPFDTLTTS 
PWLQLFINAR NWTLEGSC

Genular Protein ID: 4036281637

Symbol: Q6P4B4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6P4B4

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 3 InterPro 5 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 RefSeq 1 SMART 1 SUPFAM 3 UniPathway 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 748
  • Mass: 80186
  • Checksum: 017E6CAC4CDE9CFE
  • Sequence:
    • TITGDRRIVL VDDRECPVRR NGQGDAPPTP LPTPVDLELE WVLGKMPRKE FFLQRKPPML 
QPLALPPGLS VHQALERVLR LPAVASKRYL TNKVDRSVGG LVAQQQCVGP LQTPLADVAV 
VALSHEELIG AATALGEQPV KSLLDPKVAA RLAVAEALTN LVFALVTDLR DVKCSGNWMW 
AAKLPGEGAA LADACEAMVA VMAALGVAVD GGKDSLSMAA RVGTETVRAP GSLVISAYAV 
CPDITATVTP DLKHPEGRGH LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR 
AFSITQGLLK DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD VLSVLFAEEP 
GLVLEVQEPD LAQVLKRYRD AGLHCLELGH TGEAGPHAMV RVSVNGAVVL EEPVGELRAL 
WEETSFQLDR LQAEPRCVAE EERGLRERMG PSYCLPPTFP KASVPREPGG PSPRVAILRE 
EGSNGDREMA DAFHLAGFEV WDVTMQDLCS GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA 
AAVTFHPRAG AELRRFRKRP DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP 
GLLLRHNLSG RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF SSPELQAQIE 
ARGLAPLHWA DDDGNPTEQY PLNPNGSPGG VAGICSCDGR HLAVMPHPER AVRPWQWAWR 
PPPFDTLTTS PWLQLFINAR NWTLEGSC

Genular Protein ID: 3450223023

Symbol: A8K9T9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K9T9

Database IDs:

ARBA 12 BioGRID-ORCS 1 CDD 3 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 4 HAMAP 1 InterPro 8 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 1 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 8 PharmGKB 1 RefSeq 1 SMART 1 SUPFAM 5 UniPathway 1

Sequence Information:

  • Length: 1338
  • Mass: 144643
  • Checksum: 9EC9A465396B59AA
  • Sequence:
    • MSPVLHFYVR PSGHEGAAPG HTRRKLQGKL PELQGVETEL CYNVNWTAEA LPSAEETKKL 
MWLFGCPLLL DDVARESWLL PGSNDLLLEV GPRLNFSTPT STNIVSVCRA TGLGPVDRVE 
TTRRYRLSFA HPPSAEVEAI ALATLHDRMT EQHFPHPIQS FSPESMPEPL NGPINILGEG 
RLALEKANQE LGLALDSWDL DFYTKRFQEL QRNPSTVEAF DLAQSNSEHS RHWFFKGQLH 
VDGQKLVHSL FESIMSTQES SNPNNVLKFC DNSSAIQGKE VRFLRPEDPT RPSRFQQQQG 
LRHVVFTAET HNFPTGVCPF SGATTGTGGR IRDVQCTGRG AHVVAGTAGY CFGNLHIPGY 
NLPWEDPSFQ YPGNFARPLE VAIEASNGAS DYGNKFGEPV LAGFARSLGL QLPDGQRREW 
IKPIMFSGGI GSMEADHISK EAPEPGMEVV KVGGPVYRIG VGGGAASSVQ VQGDNTSDLD 
FGAVQRGDPE MEQKMNRVIR ACVEAPKGNP ICSLHDQGAG GNGNVLKELS DPAGAIIYTS 
RFQLGDPTLN ALEIWGAEYQ ESNALLLRSP NRDFLTHVSA RERCPACFVG TITGDRRIVL 
VDDRECPVRR NGQGDAPPTP LPTPVDLELG WVLGKMPRKE FFLQRKPPML QPLALPPGLS 
VHQALERVLR LPAVASKRYL TNKVDRSVGG LVAQQQCVGP LQTPLADVAV VALSHEELIG 
AATALGEQPV KSLLDPKVAA RLAVAEALTN LVFALVTDLR DVKCSGNWMW AAKLPGEGAA 
LADACEAMVA VMAALGVAVD GGKDSLSMAA RVGTETVRAP GSLVISAYAV CPDITATVTP 
DLKHPEGRGH LLYVALSPGQ HRLGGTALAQ CFSQLGEHPP DLDLPENLVR AFSITQGLLK 
DRLLCSGHDV SDGGLVTCLL EMAFAGNCGL QVDVPVPRVD VLSVLFAEEP GLVLEVQEPD 
LAQVLKRYRD AGLHCLELGH TGEAGPHAMV RVSVNGAVVL EEPVGELRAL WEETSFQLDR 
LQAEPRCVAE EERGLRERMG PSYCLPPTFP KASVPREPGG PSPRVAILRE EGSNGDREMA 
DAFHLAGFEV WDVTMQDLCS GAIGLDTFRG VAFVGGFSYA DVLGSAKGWA AAVTFHPRAG 
AELRRFRKRP DTFSLGVCNG CQLLALLGWV GGDPNEDAAE MGPDSQPARP GLLLHHNLSG 
RYESRWASVR VGPGPALMLR GMEGAVLPVW SAHGEGYVAF SSPELQAQIE ARGLAPLHWA 
DDDGNPTEQY PLNPNGSPGG VAGICSCDGR HLAVMPHPER AVRPWQWAWR PPPFDTLTTS 
PWLQLFINAR NWTLEGSC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.