Details for: PLCD1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 72.0691
Cell Significance Index: -11.2100 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 43.1708
Cell Significance Index: -10.9500 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 9.1001
Cell Significance Index: -11.2200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 3.6583
Cell Significance Index: -9.8000 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 2.8535
Cell Significance Index: -11.2600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 2.3760
Cell Significance Index: -5.2000 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 2.2155
Cell Significance Index: 421.6300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 1.4035
Cell Significance Index: 72.9100 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9277
Cell Significance Index: 837.6500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.8959
Cell Significance Index: 8.2500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.8701
Cell Significance Index: 39.4400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6288
Cell Significance Index: 68.3900 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.5527
Cell Significance Index: 33.1800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5399
Cell Significance Index: 87.8100 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.5321
Cell Significance Index: 7.2600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.4031
Cell Significance Index: 6.0400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.3966
Cell Significance Index: 5.6800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3460
Cell Significance Index: 23.9300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3371
Cell Significance Index: 9.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.3014
Cell Significance Index: 6.5300 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2388
Cell Significance Index: 6.8800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2354
Cell Significance Index: 28.9400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2260
Cell Significance Index: 40.7400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.2258
Cell Significance Index: 26.3100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2240
Cell Significance Index: 7.8700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.2201
Cell Significance Index: 28.2100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1926
Cell Significance Index: 26.4500 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.1784
Cell Significance Index: 2.5400 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.1658
Cell Significance Index: 4.8700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1567
Cell Significance Index: 15.5000 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1300
Cell Significance Index: 89.9200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.1085
Cell Significance Index: 21.5300 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.1055
Cell Significance Index: 0.7000 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.1040
Cell Significance Index: 2.8300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.0744
Cell Significance Index: 3.4700 - Cell Name: keratocyte (CL0002363)
Fold Change: 0.0681
Cell Significance Index: 1.0800 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0651
Cell Significance Index: 1.7500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0535
Cell Significance Index: 23.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0392
Cell Significance Index: 7.8700 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: 0.0287
Cell Significance Index: 0.4800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0276
Cell Significance Index: 0.6900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0204
Cell Significance Index: 11.1500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0143
Cell Significance Index: 2.0800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0058
Cell Significance Index: 10.9800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0055
Cell Significance Index: 8.5200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0007
Cell Significance Index: -1.3800 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0026
Cell Significance Index: -0.1300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0041
Cell Significance Index: -2.5800 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0070
Cell Significance Index: -5.1600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0079
Cell Significance Index: -10.6900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0091
Cell Significance Index: -3.2700 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0109
Cell Significance Index: -8.2400 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0122
Cell Significance Index: -0.3900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0132
Cell Significance Index: -5.9800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0168
Cell Significance Index: -12.4400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0182
Cell Significance Index: -1.0200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0208
Cell Significance Index: -12.9900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0218
Cell Significance Index: -12.3200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0229
Cell Significance Index: -2.9600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0258
Cell Significance Index: -0.5500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0267
Cell Significance Index: -7.6700 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0323
Cell Significance Index: -3.3000 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0355
Cell Significance Index: -6.0700 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0381
Cell Significance Index: -0.7900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0409
Cell Significance Index: -3.0500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0416
Cell Significance Index: -4.7700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0629
Cell Significance Index: -13.2500 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0661
Cell Significance Index: -1.2900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0679
Cell Significance Index: -8.0100 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.0737
Cell Significance Index: -1.0300 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0856
Cell Significance Index: -6.5700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0920
Cell Significance Index: -4.7900 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0968
Cell Significance Index: -5.0800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0969
Cell Significance Index: -4.5600 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1016
Cell Significance Index: -10.5800 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1031
Cell Significance Index: -7.2900 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: -0.1126
Cell Significance Index: -1.2200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1140
Cell Significance Index: -6.9900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1189
Cell Significance Index: -7.6700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1193
Cell Significance Index: -9.4500 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1269
Cell Significance Index: -7.8000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1461
Cell Significance Index: -9.2100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1476
Cell Significance Index: -3.0900 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.1481
Cell Significance Index: -2.5600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1483
Cell Significance Index: -3.1700 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1560
Cell Significance Index: -1.6200 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.1564
Cell Significance Index: -2.6300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1575
Cell Significance Index: -10.5900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1578
Cell Significance Index: -4.1500 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1655
Cell Significance Index: -5.7500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2007
Cell Significance Index: -5.1600 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.2327
Cell Significance Index: -2.9800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.2363
Cell Significance Index: -10.4500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.2515
Cell Significance Index: -8.8100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2672
Cell Significance Index: -9.8100 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2784
Cell Significance Index: -8.2000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.2799
Cell Significance Index: -10.6000 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.2800
Cell Significance Index: -2.3800 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.2812
Cell Significance Index: -8.0600 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.2883
Cell Significance Index: -4.9700
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2832351139
Symbol: PLCD1_HUMAN
Name: Phosphoinositide phospholipase C-delta-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7890667
Title: Cloning and identification of amino acid residues of human phospholipase C delta 1 essential for catalysis.
PubMed ID: 7890667
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16641997
Title: The DNA sequence, annotation and analysis of human chromosome 3.
PubMed ID: 16641997
DOI: 10.1038/nature04728
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9188725
Title: Phosphoinositide binding specificity among phospholipase C isozymes as determined by photo-cross-linking to novel substrate and product analogs.
PubMed ID: 9188725
DOI: 10.1021/bi9702288
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 21665001
Title: Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1.
PubMed ID: 21665001
Sequence Information:
- Length: 756
- Mass: 85665
- Checksum: 6C6FD7F89BA08C83
- Sequence:
MDSGRDFLTL HGLQDDEDLQ ALLKGSQLLK VKSSSWRRER FYKLQEDCKT IWQESRKVMR TPESQLFSIE DIQEVRMGHR TEGLEKFARD VPEDRCFSIV FKDQRNTLDL IAPSPADAQH WVLGLHKIIH HSGSMDQRQK LQHWIHSCLR KADKNKDNKM SFKELQNFLK ELNIQVDDSY ARKIFRECDH SQTDSLEDEE IEAFYKMLTQ RVEIDRTFAE AAGSGETLSV DQLVTFLQHQ QREEAAGPAL ALSLIERYEP SETAKAQRQM TKDGFLMYLL SADGSAFSLA HRRVYQDMGQ PLSHYLVSSS HNTYLLEDQL AGPSSTEAYI RALCKGCRCL ELDCWDGPNQ EPIIYHGYTF TSKILFCDVL RAIRDYAFKA SPYPVILSLE NHCTLEQQRV MARHLHAILG PMLLNRPLDG VTNSLPSPEQ LKGKILLKGK KLGGLLPPGG EGGPEATVVS DEDEAAEMED EAVRSRVQHK PKEDKLRLAQ ELSDMVIYCK SVHFGGFSSP GTPGQAFYEM ASFSENRALR LLQESGNGFV RHNVGHLSRI YPAGWRTDSS NYSPVEMWNG GCQIVALNFQ TPGPEMDVYQ GRFQDNGACG YVLKPAFLRD PNGTFNPRAL AQGPWWARKR LNIRVISGQQ LPKVNKNKNS IVDPKVTVEI HGVSRDVASR QTAVITNNGF NPWWDTEFAF EVVVPDLALI RFLVEDYDAS SKNDFIGQST IPLNSLKQGY RHVHLMSKNG DQHPSATLFV KISLQD
Genular Protein ID: 985926484
Symbol: A8K8F9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 756
- Mass: 85605
- Checksum: 996067F724059629
- Sequence:
MDSGRDFLTL HGLQDDEDLQ ALLKGSQLLK VKSSSWRRER FYKLQEDCKT IWQESRKVMR TPESQLFSIE DIQEVRMGHR TEGLEKFARD VPEDRCFSIV FKDQRNTLDL IAPSPADAQH WVLGLHKIIH HSGSMDQRQK LQHWIHSCLR KADKNKDNKM SFKELQNFLK ELNIQVDDSY ARKIFRECDH SQTDSLEDEE IEAFYKMLTQ RVEIDRTFAE AAGSGETLSV DQLVTFLQHQ QREEAAGPAL ALSLIERYEP SETAKAQRQM TKDGFLMYLL SADGSAFSLA HRRVYQDMGQ PLSHYLVSSS HNTYLLEDQL AGPSSTEAYI RALCKGCRCL ELDCWDGPNQ EPIIYHGYTF TSKILFCDVL RAIRDYAFKA SPYPVILSLE NHCTLEQQRV MARHLHAILG PMLLNRPLDG VTNSLPSPEQ LKGKILLKGK KLGGLLPPGG EGGPEATVVS DEDEAAEMED EAVRSRVQHK PKEDKLRLAQ ELSDMVIYCK SVHFGGFSSP GTPGQAFYEM ASFSENRALR LLQESGNGFV RHNVGHLSRI YPAGWRTDSS NYSPVEMWNG GCQIVALNSQ TPGPEMDVYQ GRFQDNGACG YVLKPAFLRD PNGTFNPRAL AQGPWWARKR LNIRVISGQQ LPKVNKNKNS IVDPKVTVEI HGVSRDVASR QTAVITNNGF NPWWDTEFAF EVVVPDLALI RFLVEDYDAS SKNDFIGQST IPLNSLKQGY RHVHLMSKNG DQHPSATLFV KISLQD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.