Details for: PMS1

Gene ID: 5378

Symbol: PMS1

Ensembl ID: ENSG00000064933

Description: PMS1 homolog 1, mismatch repair system component

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 209.3282
    Cell Significance Index: -32.5600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 121.1346
    Cell Significance Index: -30.7300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 73.6249
    Cell Significance Index: -34.7600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 71.4080
    Cell Significance Index: -29.0100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 30.5894
    Cell Significance Index: -29.2100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 27.4868
    Cell Significance Index: -33.8900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.1208
    Cell Significance Index: -32.4700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 10.3436
    Cell Significance Index: -31.7700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.3668
    Cell Significance Index: -20.5000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.6960
    Cell Significance Index: -34.3200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.1242
    Cell Significance Index: 421.5600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.8536
    Cell Significance Index: 371.8300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5080
    Cell Significance Index: 149.1800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.4280
    Cell Significance Index: 80.1300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2367
    Cell Significance Index: 443.5800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0077
    Cell Significance Index: 909.8900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.7323
    Cell Significance Index: 45.0100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7298
    Cell Significance Index: 118.7000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.7112
    Cell Significance Index: 77.3600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.6409
    Cell Significance Index: 15.3700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.6345
    Cell Significance Index: 7.8700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6201
    Cell Significance Index: 17.3300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.6164
    Cell Significance Index: 426.3400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.5937
    Cell Significance Index: 35.6400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.5012
    Cell Significance Index: 18.9800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4857
    Cell Significance Index: 21.4900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4403
    Cell Significance Index: 9.6400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3807
    Cell Significance Index: 7.4300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3563
    Cell Significance Index: 10.2700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.3501
    Cell Significance Index: 26.8700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3415
    Cell Significance Index: 46.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.3337
    Cell Significance Index: 21.0300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2842
    Cell Significance Index: 33.5100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2433
    Cell Significance Index: 5.2700
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.2382
    Cell Significance Index: 2.8400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2199
    Cell Significance Index: 15.2100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2047
    Cell Significance Index: 36.9000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1941
    Cell Significance Index: 8.8000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1845
    Cell Significance Index: 100.7700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1772
    Cell Significance Index: 33.7300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1497
    Cell Significance Index: 66.1800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1420
    Cell Significance Index: 9.5500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1164
    Cell Significance Index: 14.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1156
    Cell Significance Index: 2.8900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1004
    Cell Significance Index: 1.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0719
    Cell Significance Index: 135.3200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0620
    Cell Significance Index: 7.9500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0560
    Cell Significance Index: 35.5700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0303
    Cell Significance Index: 1.0700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0288
    Cell Significance Index: 0.7400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0258
    Cell Significance Index: 47.6400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0255
    Cell Significance Index: 39.2100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0232
    Cell Significance Index: 10.5400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0180
    Cell Significance Index: 0.9400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0103
    Cell Significance Index: 0.6600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0013
    Cell Significance Index: -1.8000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0217
    Cell Significance Index: -3.1600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0217
    Cell Significance Index: -1.0100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0289
    Cell Significance Index: -21.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0375
    Cell Significance Index: -28.4000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0385
    Cell Significance Index: -28.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0402
    Cell Significance Index: -2.0900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0526
    Cell Significance Index: -1.1200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0556
    Cell Significance Index: -31.3500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0604
    Cell Significance Index: -37.6900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0681
    Cell Significance Index: -1.1400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0813
    Cell Significance Index: -13.8900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0987
    Cell Significance Index: -10.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1048
    Cell Significance Index: -30.1600
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1142
    Cell Significance Index: -3.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1215
    Cell Significance Index: -14.1600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1427
    Cell Significance Index: -2.9600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1456
    Cell Significance Index: -10.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1560
    Cell Significance Index: -8.1900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1633
    Cell Significance Index: -7.6800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1689
    Cell Significance Index: -4.8200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1754
    Cell Significance Index: -36.9400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1802
    Cell Significance Index: -23.2800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1901
    Cell Significance Index: -5.0000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2381
    Cell Significance Index: -24.8000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2406
    Cell Significance Index: -27.5700
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2625
    Cell Significance Index: -3.7700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3166
    Cell Significance Index: -6.7200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.3236
    Cell Significance Index: -24.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3650
    Cell Significance Index: -11.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3852
    Cell Significance Index: -30.5100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3899
    Cell Significance Index: -13.5500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3913
    Cell Significance Index: -4.8800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3965
    Cell Significance Index: -7.9600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4256
    Cell Significance Index: -11.4100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4712
    Cell Significance Index: -28.8900
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.4916
    Cell Significance Index: -12.5600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4952
    Cell Significance Index: -15.7700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.4982
    Cell Significance Index: -3.0100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4985
    Cell Significance Index: -16.3200
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.5112
    Cell Significance Index: -3.9400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5204
    Cell Significance Index: -10.2900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.5515
    Cell Significance Index: -6.9600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.6135
    Cell Significance Index: -8.3700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.6262
    Cell Significance Index: -9.2400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The PMS1 gene is a member of the MutLalpha complex, a heterodimeric enzyme that recognizes and binds to mismatched DNA bases. This binding event triggers a series of protein-protein interactions that ultimately lead to the excision of the mismatched bases and the restoration of the original DNA sequence. The PMS1 protein is highly conserved across species, with high sequence identity to its human ortholog, suggesting a conserved functional role. **Pathways and Functions:** The PMS1 gene is involved in several key pathways, including: 1. **Mismatch Repair (MMR)**: The PMS1 gene is a critical component of the MMR system, which corrects errors in DNA replication and recombination. The PMS1 protein recognizes and binds to mismatched DNA bases, triggering a series of protein-protein interactions that ultimately lead to the excision of the mismatched bases. 2. **ATP-dependent DNA Damage Sensor Activity**: The PMS1 gene is also involved in the recognition and response to DNA damage, particularly ATM and ATR-mediated signaling pathways. 3. **DNA Binding**: The PMS1 protein binds to mismatched DNA bases, recognizing and binding to specific sequences. 4. **Protein Binding**: The PMS1 protein interacts with other proteins involved in the MMR system, including MutL and MutS. **Clinical Significance:** Dysregulation of the PMS1 gene has been implicated in various neurological disorders, including: 1. **Neurodegenerative diseases**: Mutations in the PMS1 gene have been associated with neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. **Cancer**: The PMS1 gene is also involved in cancer development, with mutations in the PMS1 gene leading to increased tumorigenesis and tumor progression. 3. **Neurodevelopmental disorders**: The PMS1 gene has been implicated in neurodevelopmental disorders such as autism spectrum disorder and schizophrenia. In conclusion, the PMS1 gene is a critical component of the MMR system, essential for maintaining genome stability and preventing neurodegeneration. Dysregulation of the PMS1 gene has been implicated in various neurological disorders, highlighting the importance of this gene in human health and disease. Further research is needed to fully understand the role of the PMS1 gene in neurological function and disease.

Genular Protein ID: 1708924517

Symbol: PMS1_HUMAN

Name: PMS1 protein homolog 1

UniProtKB Accession Codes:

P54277 D3DPI1 Q4VAL4 Q5FBZ3 Q5FBZ6 Q5FBZ8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CORUM 1 CPTC 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 10 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 RefSeq 10 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8072530

Title: Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.

PubMed ID: 8072530

DOI: 10.1038/371075a0

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10748105

Title: Identification of a second MutL DNA mismatch repair complex (hPMS1 and hMLH1) in human epithelial cells.

PubMed ID: 10748105

DOI: 10.1074/jbc.m908768199

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 26300262

Title: MCM9 Is Required for Mammalian DNA Mismatch Repair.

PubMed ID: 26300262

DOI: 10.1016/j.molcel.2015.07.010

PubMed ID: 10480359

Title: Prevalence of germline mutations of hMLH1, hMSH2, hPMS1, hPMS2, and hMSH6 genes in 75 French kindreds with nonpolyposis colorectal cancer.

PubMed ID: 10480359

DOI: 10.1007/s004399900064

Sequence Information:

  • Length: 932
  • Mass: 105830
  • Checksum: EC4F402937B616DF
  • Sequence:
    • MKQLPAATVR LLSSSQIITS VVSVVKELIE NSLDAGATSV DVKLENYGFD KIEVRDNGEG 
IKAVDAPVMA MKYYTSKINS HEDLENLTTY GFRGEALGSI CCIAEVLITT RTAADNFSTQ 
YVLDGSGHIL SQKPSHLGQG TTVTALRLFK NLPVRKQFYS TAKKCKDEIK KIQDLLMSFG 
ILKPDLRIVF VHNKAVIWQK SRVSDHKMAL MSVLGTAVMN NMESFQYHSE ESQIYLSGFL 
PKCDADHSFT SLSTPERSFI FINSRPVHQK DILKLIRHHY NLKCLKESTR LYPVFFLKID 
VPTADVDVNL TPDKSQVLLQ NKESVLIALE NLMTTCYGPL PSTNSYENNK TDVSAADIVL 
SKTAETDVLF NKVESSGKNY SNVDTSVIPF QNDMHNDESG KNTDDCLNHQ ISIGDFGYGH 
CSSEISNIDK NTKNAFQDIS MSNVSWENSQ TEYSKTCFIS SVKHTQSENG NKDHIDESGE 
NEEEAGLENS SEISADEWSR GNILKNSVGE NIEPVKILVP EKSLPCKVSN NNYPIPEQMN 
LNEDSCNKKS NVIDNKSGKV TAYDLLSNRV IKKPMSASAL FVQDHRPQFL IENPKTSLED 
ATLQIEELWK TLSEEEKLKY EEKATKDLER YNSQMKRAIE QESQMSLKDG RKKIKPTSAW 
NLAQKHKLKT SLSNQPKLDE LLQSQIEKRR SQNIKMVQIP FSMKNLKINF KKQNKVDLEE 
KDEPCLIHNL RFPDAWLMTS KTEVMLLNPY RVEEALLFKR LLENHKLPAE PLEKPIMLTE 
SLFNGSHYLD VLYKMTADDQ RYSGSTYLSD PRLTANGFKI KLIPGVSITE NYLEIEGMAN 
CLPFYGVADL KEILNAILNR NAKEVYECRP RKVISYLEGE AVRLSRQLPM YLSKEDIQDI 
IYRMKHQFGN EIKECVHGRP FFHHLTYLPE TT

Genular Protein ID: 4003366922

Symbol: B4DIH7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DIH7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 2 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 756
  • Mass: 86529
  • Checksum: D1EE8A7E375944C3
  • Sequence:
    • MSFGILKPDL RIVFVHNKAV IWQKSRVSDH KMALMSVLGT AVMNNMESFQ YHSEESQIYL 
SGFLPKCDAD HSFTSLSTPE RSFIFINSRP VHQKDILKLI RHHYNLKCLK ESTRLYPVFF 
LKIDVPTADV DVNLTPDKSQ VLLQNKESVL IALENLMTTC YGPLPSTNSY ENNKTDVSAA 
DIVLSKTAET DVLFNKVESS GKNYSNVDTS VIPFQNDMHN DESGKNTDDC LNHQISIGDF 
GYGHCSSEIS NIDKNTKNAF QDISMSNVSW ENSQTEYSKT CFISSVKHTQ SENGNKDHID 
ESGENEEEAG LENSSEISAD EWSRGNILKN SVGENIEPVK ILVPEKSLPC KVSNNNYPIP 
EQMNLNEDSC NKKSNVIDNK SGKVTAYDLL SNRVIKKPMS ASALFVQDHR PQFLIENPKT 
SLEDATLQIE ELWKTLSEEE KLKYEEKATK DLERYNSQMK RAIEQESQMS LKDGRKKIKP 
TSAWNLAQKH KLKTSLSNQP KLDELLQSQI EKRRSQNIKM VQIPFSMKNL KINFKKQNKV 
DLEEKDEPCL IHNLRFPDAW LMTSKTEVML LNPYRVEEAL LFKRLLENHK LPAEPLEKPI 
MLTESLFNGS HYLDVLYKMT ADDQRYSGST YLSDPRLTAN GFKIKLIPGV SITENYLEIE 
GMANCLPFYG VADLKEILNA ILNRNAKEVY ECRPRKVIGY LEGEAVRLSR QLPMYLSKED 
IQDIIYRMKH QFGNEIKECV HGRPFFHHLT YLPETT

Genular Protein ID: 3164191988

Symbol: Q5XG96_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q5XG96

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 4 Gene3D 1 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 165
  • Mass: 17838
  • Checksum: 2E2D124D4EDA8BF6
  • Sequence:
    • MKQLPAATVR LLSSSQIITS VVSVVKELIE NSLDAGATSV DVKLENYGFD KIEVRDNGEG 
IKAVDAPVMA MKYYTSKINS HEDLENLTTY GFRGEALGSI CCIAEVLITT RTAADNFSTQ 
YVLDGSGHIL SQKPSHLGQG SHSVTQAGLQ WHHLGSLQPL PPRLK

Genular Protein ID: 1772631229

Symbol: B7ZAA0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZAA0

Database IDs:

Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 3 GO 7 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 8 SAM 1 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

Sequence Information:

  • Length: 756
  • Mass: 86559
  • Checksum: D1FA9E7E234D44C3
  • Sequence:
    • MSFGILKPDL RIVFVHNKAV IWQKSRVSDH KMALMSVLGT AVMNNMESFQ YHSEESQIYL 
SGFLPKCDAD HSFTSLSTPE RSFIFINSRP VHQKDILKLI RHHYNLKCLK ESTRLYPVFF 
LKIDVPTADV DVNLTPDKSQ VLLQNKESVL IALENLMTTC YGPLPSTNSY ENNKTDVSAA 
DIVLSKTAET DVLFNKVESS GKNYSNVDTS VIPFQNDMHN DESGKNTDDC LNHQISIGDF 
GYGHCSSEIS NIDKNTKNAF QDISMSNVSW ENSQTEYSKT CFISSVKHTQ SENGNKDHID 
ESGENEEEAG LENSSEISAD EWSRGNILKN SVGENIEPVK ILVPEKSLPC KVSNNNYPIP 
EQMNLNEDSC NKKSNVIDNK SGKVTAYDLL SNRVIKKPMS ASALFVQDHR PQFLIENPKT 
SLEDATLQIE ELWKTLSEEE KLKYEEKATK DLERYNSQMK RAIEQESQMS LKDGRKKIKP 
TSAWNLAQKH KLKTSLSNQP KLDELLQSQI EKRRSQNIKM VQIPFSMKNL KINFKKQNKV 
DLEEKDEPCL IHNLRFPDAW LMTSKTEVML LNPYRVEEAL LFKRLLENHK LPAEPLEKPI 
MLTESLFNGS HYLDVLYKMT ADDQRYSGST YLSDPRLTAN GFKIKLIPGV SITENYLEIE 
GMANCLPFYG VADLKEILNA ILNRNAKEVY ECRPRKVISY LEGEAVRLSR QLPMYLSKED 
IQDIIYRMKH QFGNEIKECV HGRPFFHHLT YLPETT

Genular Protein ID: 1951886414

Symbol: E9PC40_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PC40

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 181
  • Mass: 19862
  • Checksum: 566E0CFE169FC62A
  • Sequence:
    • MKQLPAATVR LLSSSQIITS VVSVVKELIE NSLDAGATSV DVKLENYGFD KIEVRDNGEG 
IKAVDAPVMA MKYYTSKINS HEDLENLTTY GFRGEALGSI CCIAEVLITT RTAADNFSTQ 
YVLDGSGHIL SQKPSHLGQG KKVALYTNIL YLFCLNCWFK KKKLLGEYKY IALGLVLIKA 
S

Genular Protein ID: 1399718577

Symbol: I6L9H5_HUMAN

Name: N/A

UniProtKB Accession Codes:

I6L9H5

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 3 InterPro 9 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 2 SUPFAM 3

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 669
  • Mass: 74741
  • Checksum: 42013A1AF27E2C53
  • Sequence:
    • MKQLPAATVR LLSSSQIITS VVSVVKELIE NSLDAGATSV DVKLENYGFD KIEVRDNGEG 
IKAVDAPVMA MKYYTSKINS HEDLENLTTY GFRGEALGSI CCIAEVLITT RTAADNFSTQ 
YVLDGSGHIL SQKPSHLGQG TTVTALRLFK NLPVRKQFYS TAKKCKDEIK KIQDLLMSFG 
ILKPDLRIVF VHNKAVIWQK SRVSDHKMAL MSVLGTAVMN NMESFQYHSE ESQIYLSGFL 
PKCDADHSFT SLSTPERSFI FINSRPVHQK DILKLIRHHY NLKCLKESTR LYPVFFLKID 
VPTADVDVNL TPDKSQVLLQ NKESVLIALE NLMTTCYGPL PSTNSYENNK TDVSAADIVL 
SKTAETDVLF NKVESSGKNY SNVDTSVIPF QNDMHNDESG KNTDDCLNHQ ISIGDFGYGH 
CSSEISNIDK NTKNAFQDIS MSNVSWENSQ TEYSKTCFIS SVKHTQSENG NKDHIDESGE 
NEEEAGLENS SEISADEWSR GNILKNSVGE NIEPVKILVP EKSLPCKVSN NNYPIPEQMN 
LNEDSCNKKS NVIDNKSGKV TAYDLLSNRV IKKPMSASAL FVQDHRPQFL IENPKTSLED 
ATLQIEELWK TLSEEEKLNL FNGSHYLDVL YKMTADDQRY SGSTYLSDPR LTANGFKIKL 
IPGVSITEN

Genular Protein ID: 4073575586

Symbol: Q3BDU3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q3BDU3

Database IDs:

ARBA 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 7 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 2 SUPFAM 3 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 659
  • Mass: 74058
  • Checksum: EF56E207736E2F62
  • Sequence:
    • MKQLPAATVR LLSSSQIITS VVSVVKELIE NSLDAGATSV DVKLENYGFD KIEVRDNGEG 
IKAVDAPVMA MKYYTSKINS HEDLENLTTY GFRGEALGSI CCIAEVLITT RTAADNFSTQ 
YVLDGSGHIL SQKPSHLGQG TTVTALRLFK NLPVRKQFYS TAKKCKDEIK KIQDLLMSFG 
ILKPDLRIVF VHNKIYLSGF LPKCDADHSF TSLSTPERSF IFINSRPVHQ KDILKLIRHH 
YNLKCLKEST RLYPVFFLKI DVPTADVDVN LTPDKSQVLL QNKESVLIAL ENLMTTCYGP 
LPSTNSYENN KTDVSAADIV LSKTAETDVL FNKVESSGKN YSNVDTSVIP FQNDMHNDES 
GKNTDDCLNH QISIGDFGYG HCSSEISNID KNTKNAFQDI SMSNVSWENS QTEYSKTCFI 
SSVKHTQSEN GNKDHIDESG ENEEEAGLEN SSEISADEWS RGNILKNSVG ENIEPVKILV 
PEKSLPCKVS NNNYPIPEQM NLNEDSCNKK SNVIDNKSGK VTAYDLLSNR VIKKPMSASA 
LFVQDHRPQF LIENPKTSLE DATLQIEELW KTLSEEEKLK YEEKATKDLE RYNSQMKRAI 
EQESQMSLKD GRKKIKPTSA WNLAQKHKLK TSLSNQPKLD ELLQSQIEKR RSQNIKMSF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.