Details for: TSPEAR AS1

Gene ID: 54082

Symbol: TSPEAR AS1

Ensembl ID: ENSG00000235890

Description: TSPEAR antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: 0.3621
    Cell Significance Index: 2.1700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.2937
    Cell Significance Index: 4.8400
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.1473
    Cell Significance Index: 1.8600
  • Cell Name: osteoclast (CL0000092)
    Fold Change: 0.0617
    Cell Significance Index: 0.6300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0436
    Cell Significance Index: 8.6500
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: 0.0365
    Cell Significance Index: 0.4200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.0347
    Cell Significance Index: 0.3200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0337
    Cell Significance Index: 1.7500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0290
    Cell Significance Index: 0.4300
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.0203
    Cell Significance Index: 0.3000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0186
    Cell Significance Index: 1.4300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.0148
    Cell Significance Index: 0.3700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0056
    Cell Significance Index: 0.2800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0047
    Cell Significance Index: 0.8400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0004
    Cell Significance Index: 0.1400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0002
    Cell Significance Index: 0.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.0002
    Cell Significance Index: 0.0900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0002
    Cell Significance Index: 0.4500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0000
    Cell Significance Index: -0.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0002
    Cell Significance Index: -0.1600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0003
    Cell Significance Index: -0.4200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0005
    Cell Significance Index: -0.7000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0007
    Cell Significance Index: -0.0800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0008
    Cell Significance Index: -0.5300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0008
    Cell Significance Index: -0.6100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0010
    Cell Significance Index: -0.4600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0010
    Cell Significance Index: -0.1100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0020
    Cell Significance Index: -0.2500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0021
    Cell Significance Index: -0.4200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0024
    Cell Significance Index: -0.0400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0028
    Cell Significance Index: -0.3800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0031
    Cell Significance Index: -0.6600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0035
    Cell Significance Index: -0.5900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0045
    Cell Significance Index: -0.0800
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0048
    Cell Significance Index: -0.0600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0052
    Cell Significance Index: -0.5300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0052
    Cell Significance Index: -0.3200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0055
    Cell Significance Index: -0.3100
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: -0.0059
    Cell Significance Index: -0.0600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0072
    Cell Significance Index: -0.7500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0096
    Cell Significance Index: -0.2000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0101
    Cell Significance Index: -0.1400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0113
    Cell Significance Index: -0.7600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0120
    Cell Significance Index: -0.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0129
    Cell Significance Index: -0.6800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0146
    Cell Significance Index: -0.4300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0147
    Cell Significance Index: -0.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0155
    Cell Significance Index: -0.7300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0156
    Cell Significance Index: -0.5900
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0179
    Cell Significance Index: -0.2300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0182
    Cell Significance Index: -0.6000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0185
    Cell Significance Index: -0.6500
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.0188
    Cell Significance Index: -0.2000
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.0190
    Cell Significance Index: -0.2700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0193
    Cell Significance Index: -0.5200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0204
    Cell Significance Index: -0.5100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0206
    Cell Significance Index: -0.5900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0210
    Cell Significance Index: -0.4100
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0213
    Cell Significance Index: -0.2600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0217
    Cell Significance Index: -0.6900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0218
    Cell Significance Index: -0.4700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0220
    Cell Significance Index: -0.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0223
    Cell Significance Index: -0.6000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0229
    Cell Significance Index: -0.6600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0232
    Cell Significance Index: -0.4700
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: -0.0240
    Cell Significance Index: -0.4100
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0254
    Cell Significance Index: -0.6100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0255
    Cell Significance Index: -0.3100
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0258
    Cell Significance Index: -0.4200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0266
    Cell Significance Index: -0.5300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0270
    Cell Significance Index: -0.7700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0270
    Cell Significance Index: -0.7100
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0271
    Cell Significance Index: -0.3200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0277
    Cell Significance Index: -0.3500
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0278
    Cell Significance Index: -0.3600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0283
    Cell Significance Index: -0.3700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0284
    Cell Significance Index: -0.7100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0284
    Cell Significance Index: -0.6000
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0294
    Cell Significance Index: -0.7500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0297
    Cell Significance Index: -0.6200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0298
    Cell Significance Index: -0.4400
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0300
    Cell Significance Index: -0.5900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0302
    Cell Significance Index: -0.6400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0312
    Cell Significance Index: -0.7800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0317
    Cell Significance Index: -0.4600
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0318
    Cell Significance Index: -0.7700
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.0330
    Cell Significance Index: -0.5700
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0341
    Cell Significance Index: -0.5100
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0351
    Cell Significance Index: -0.4500
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: -0.0354
    Cell Significance Index: -0.3900
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0360
    Cell Significance Index: -0.4800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0368
    Cell Significance Index: -0.6800
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0376
    Cell Significance Index: -0.7500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0377
    Cell Significance Index: -0.4700
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.0381
    Cell Significance Index: -0.8800
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0389
    Cell Significance Index: -0.7600
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0397
    Cell Significance Index: -0.6700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0399
    Cell Significance Index: -0.5000
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.0400
    Cell Significance Index: -0.5400
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.0403
    Cell Significance Index: -0.4200

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Non-coding RNA:** TSPEAR AS1 is an antisense RNA molecule, meaning it is transcribed from the opposite strand of the genome, and does not encode a protein. 2. **Tissue-specific expression:** TSPEAR AS1 is expressed in various cell types, including blood vessel endothelial cells, conventional dendritic cells, granulocyte monocyte progenitor cells, and stem cells from different tissues, such as the colon, brain, and retina. 3. **Regulatory functions:** TSPEAR AS1 has been implicated in regulating gene expression, modulating immune responses, and influencing cell development and differentiation. **Pathways and Functions:** 1. **Immune response regulation:** TSPEAR AS1 has been shown to modulate the function of immune cells, including dendritic cells and T cells, by regulating the expression of key immune-related genes. 2. **Cell development and differentiation:** TSPEAR AS1 plays a crucial role in the development and differentiation of various cell types, including stem cells, endothelial cells, and neurons. 3. **Gene expression regulation:** TSPEAR AS1 has been implicated in regulating the expression of genes involved in cell growth, differentiation, and survival. 4. **Tissue homeostasis:** TSPEAR AS1 contributes to maintaining tissue homeostasis by regulating the expression of genes involved in tissue repair and maintenance. **Clinical Significance:** 1. **Immunological disorders:** Dysregulation of TSPEAR AS1 expression has been implicated in various immunological disorders, including autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Cancer:** TSPEAR AS1 has been shown to play a role in cancer development and progression, particularly in the regulation of immune cell function and tumor microenvironment. 3. **Neurological disorders:** TSPEAR AS1 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 4. **Regenerative medicine:** TSPEAR AS1 has been identified as a potential therapeutic target for regenerative medicine, particularly in the development of stem cell therapies for tissue repair and regeneration. In conclusion, TSPEAR AS1 is a complex non-coding RNA molecule that plays a critical role in regulating various cellular processes, including immune response, cell development, and tissue homeostasis. Further research is needed to fully elucidate the functional significance of TSPEAR AS1 and its potential applications in immunological and regenerative medicine.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.