Details for: PTPRN2

Gene ID: 5799

Symbol: PTPRN2

Ensembl ID: ENSG00000155093

Description: protein tyrosine phosphatase receptor type N2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 312.3207
    Cell Significance Index: -48.5800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 190.2277
    Cell Significance Index: -48.2500
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 128.3901
    Cell Significance Index: -52.8900
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 100.4400
    Cell Significance Index: -47.4200
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 70.6683
    Cell Significance Index: -47.4200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 39.3688
    Cell Significance Index: -48.5400
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 15.4543
    Cell Significance Index: -41.4000
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 14.4166
    Cell Significance Index: -44.2800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 12.3136
    Cell Significance Index: -48.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 7.4958
    Cell Significance Index: 331.5600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 6.8915
    Cell Significance Index: 260.9700
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 6.2214
    Cell Significance Index: 77.1700
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 5.1070
    Cell Significance Index: 39.1700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 4.9146
    Cell Significance Index: 1762.7900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.4732
    Cell Significance Index: -9.7900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.3886
    Cell Significance Index: 679.7500
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 3.3763
    Cell Significance Index: 35.1700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.2876
    Cell Significance Index: 2273.8100
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.9154
    Cell Significance Index: 38.8900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 2.7283
    Cell Significance Index: 59.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1094
    Cell Significance Index: 57.6300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9623
    Cell Significance Index: 104.6700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9090
    Cell Significance Index: 147.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.8875
    Cell Significance Index: 53.2800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8158
    Cell Significance Index: 11.1300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.8105
    Cell Significance Index: 45.4800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7509
    Cell Significance Index: 149.0200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.6281
    Cell Significance Index: 12.4200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.6222
    Cell Significance Index: 112.1600
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: 0.5855
    Cell Significance Index: 6.4600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.5329
    Cell Significance Index: 5.0700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4637
    Cell Significance Index: 32.0700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.4540
    Cell Significance Index: 55.8200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.4511
    Cell Significance Index: 7.7300
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.4386
    Cell Significance Index: 3.6200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.3938
    Cell Significance Index: 4.9100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2740
    Cell Significance Index: 52.1500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.2543
    Cell Significance Index: 8.1000
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.2313
    Cell Significance Index: 2.5200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.2044
    Cell Significance Index: 10.7300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.1833
    Cell Significance Index: 6.0000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1697
    Cell Significance Index: 16.7900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1220
    Cell Significance Index: 3.5200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1108
    Cell Significance Index: 2.4000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0800
    Cell Significance Index: 3.6300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0529
    Cell Significance Index: 9.0300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0060
    Cell Significance Index: 9.1800
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.0025
    Cell Significance Index: 0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0031
    Cell Significance Index: -5.6600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0052
    Cell Significance Index: -9.7400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0068
    Cell Significance Index: -5.0400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0276
    Cell Significance Index: -37.5900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0335
    Cell Significance Index: -18.8800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0395
    Cell Significance Index: -0.5700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0408
    Cell Significance Index: -0.4900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0437
    Cell Significance Index: -32.0400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0451
    Cell Significance Index: -28.6500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0583
    Cell Significance Index: -44.1200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0658
    Cell Significance Index: -35.9600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0683
    Cell Significance Index: -1.4500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0713
    Cell Significance Index: -32.3800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0755
    Cell Significance Index: -47.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0762
    Cell Significance Index: -2.1300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0914
    Cell Significance Index: -40.4300
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.0959
    Cell Significance Index: -1.2100
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1173
    Cell Significance Index: -1.4800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1252
    Cell Significance Index: -17.2000
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1323
    Cell Significance Index: -38.0600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1335
    Cell Significance Index: -3.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1375
    Cell Significance Index: -19.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1479
    Cell Significance Index: -17.2400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1551
    Cell Significance Index: -32.6700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1776
    Cell Significance Index: -8.9700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1994
    Cell Significance Index: -23.5100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2344
    Cell Significance Index: -23.9500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2695
    Cell Significance Index: -34.5500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2745
    Cell Significance Index: -31.4500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3015
    Cell Significance Index: -12.3500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3066
    Cell Significance Index: -6.4000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.3296
    Cell Significance Index: -42.5800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4121
    Cell Significance Index: -13.2000
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.4206
    Cell Significance Index: -2.8500
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4304
    Cell Significance Index: -9.3000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4494
    Cell Significance Index: -35.5900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4572
    Cell Significance Index: -16.0200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4678
    Cell Significance Index: -48.7100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4685
    Cell Significance Index: -12.3200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.5158
    Cell Significance Index: -14.0400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5370
    Cell Significance Index: -40.0200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5780
    Cell Significance Index: -12.3100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5824
    Cell Significance Index: -44.6900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.5858
    Cell Significance Index: -37.7900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.6008
    Cell Significance Index: -42.4900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6017
    Cell Significance Index: -20.9100
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: -0.6174
    Cell Significance Index: -6.5600
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.6225
    Cell Significance Index: -4.0500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.6285
    Cell Significance Index: -32.7400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.6331
    Cell Significance Index: -16.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.6542
    Cell Significance Index: -41.2300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.6646
    Cell Significance Index: -7.5500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transmembrane receptor tyrosine phosphatase**: PTPRN2 is a member of the receptor-type tyrosine-protein phosphatase family, characterized by its transmembrane domain and phosphatase activity. 2. **Broad tissue expression**: PTPRN2 is widely expressed in various cell types, including endocrine cells, neurons, and immune cells, such as macrophages and neutrophils. 3. **Diverse signaling pathways**: PTPRN2 interacts with multiple signaling pathways, including those involved in immune regulation, neurotransmission, and metabolic processes. **Pathways and Functions:** 1. **Immune system regulation**: PTPRN2 modulates the activity of immune cells, such as neutrophils and macrophages, influencing their degranulation, phagocytosis, and cytokine production. 2. **Neurotransmitter secretion**: PTPRN2 is involved in the regulation of neurotransmitter release from synaptic vesicles, impacting synaptic transmission and neuronal function. 3. **Insulin secretion**: PTPRN2 plays a role in the regulation of insulin secretion in response to glucose stimuli, highlighting its importance in glucose metabolism and energy homeostasis. 4. **Lipid metabolic process**: PTPRN2 is implicated in the regulation of lipid metabolism, influencing the activity of enzymes involved in lipid synthesis and degradation. 5. **Protein dephosphorylation**: As a phosphatase, PTPRN2 dephosphorylates and regulates the activity of downstream signaling molecules, including tyrosine kinases and other phosphatases. **Clinical Significance:** 1. **Autoimmune disorders**: Alterations in PTPRN2 expression and function have been implicated in various autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. 2. **Neurological disorders**: Dysregulation of PTPRN2 has been linked to neurological conditions, including Alzheimer's disease, Parkinson's disease, and schizophrenia. 3. **Cancer**: PTPRN2 has been identified as a potential oncogene, with overexpression associated with increased tumorigenesis and metastasis. 4. **Metabolic disorders**: PTPRN2 plays a crucial role in glucose metabolism, and its dysregulation has been implicated in the development of type 2 diabetes and metabolic syndrome. In conclusion, PTPRN2 is a multifunctional gene that plays a critical role in regulating immune responses, neurotransmission, and metabolic processes. Its dysregulation has been implicated in various disease states, highlighting the importance of further research into the mechanisms of PTPRN2 function and its potential as a therapeutic target.

Genular Protein ID: 4150294523

Symbol: PTPR2_HUMAN

Name: Receptor-type tyrosine-protein phosphatase N2

UniProtKB Accession Codes:

Q92932 E9PC57 Q8N4I5 Q92662 Q9Y4F8 Q9Y4I6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 4 ChiTaRS 1 DEPOD 1 DMDM 1 DNASU 1 DisGeNET 1 EC 2 EMBL 15 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 13 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 2 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 1 RefSeq 5 Rhea 3 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8878534

Title: Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes.

PubMed ID: 8878534

DOI: 10.1006/bbrc.1996.1526

PubMed ID: 8954911

Title: ICAAR, a novel member of a new family of transmembrane, tyrosine phosphatase-like proteins.

PubMed ID: 8954911

DOI: 10.1006/bbrc.1996.1817

PubMed ID: 8798755

Title: Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes.

PubMed ID: 8798755

DOI: 10.1074/jbc.271.40.24817

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8637868

Title: Identification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragment.

PubMed ID: 8637868

DOI: 10.1073/pnas.93.6.2307

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 26620550

Title: PTPRN2 and PLCbeta1 promote metastatic breast cancer cell migration through PI(4,5)P2-dependent actin remodeling.

PubMed ID: 26620550

DOI: 10.15252/embj.201591973

PubMed ID: 19167335

Title: Large-scale structural analysis of the classical human protein tyrosine phosphatome.

PubMed ID: 19167335

DOI: 10.1016/j.cell.2008.11.038

PubMed ID: 25421040

Title: X-ray structure of the mature ectodomain of phogrin.

PubMed ID: 25421040

DOI: 10.1007/s10969-014-9191-0

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

  • Length: 1015
  • Mass: 111271
  • Checksum: 950C15CA89DBC029
  • Sequence:
    • MGPPLPLLLL LLLLLPPRVL PAAPSSVPRG RQLPGRLGCL LEEGLCGASE ACVNDGVFGR 
CQKVPAMDFY RYEVSPVALQ RLRVALQKLS GTGFTWQDDY TQYVMDQELA DLPKTYLRRP 
EASSPARPSK HSVGSERRYS REGGAALANA LRRHLPFLEA LSQAPASDVL ARTHTAQDRP 
PAEGDDRFSE SILTYVAHTS ALTYPPGSRT QLREDLLPRT LGQLQPDELS PKVDSGVDRH 
HLMAALSAYA AQRPPAPPGE GSLEPQYLLR APSRMPRPLL APAAPQKWPS PLGDSEDPSS 
TGDGARIHTL LKDLQRQPAE VRGLSGLELD GMAELMAGLM QGVDHGVARG SPGRAALGES 
GEQADGPKAT LRGDSFPDDG VQDDDDRLYQ EVHRLSATLG GLLQDHGSRL LPGALPFARP 
LDMERKKSEH PESSLSSEEE TAGVENVKSQ TYSKDLLGQQ PHSEPGAAAF GELQNQMPGP 
SKEEQSLPAG AQEALSDGLQ LEVQPSEEEA RGYIVTDRDP LRPEEGRRLV EDVARLLQVP 
SSAFADVEVL GPAVTFKVSA NVQNVTTEDV EKATVDNKDK LEETSGLKIL QTGVGSKSKL 
KFLPPQAEQE DSTKFIALTL VSLACILGVL LASGLIYCLR HSSQHRLKEK LSGLGGDPGA 
DATAAYQELC RQRMATRPPD RPEGPHTSRI SSVSSQFSDG PIPSPSARSS ASSWSEEPVQ 
SNMDISTGHM ILSYMEDHLK NKNRLEKEWE ALCAYQAEPN SSFVAQREEN VPKNRSLAVL 
TYDHSRVLLK AENSHSHSDY INASPIMDHD PRNPAYIATQ GPLPATVADF WQMVWESGCV 
VIVMLTPLAE NGVRQCYHYW PDEGSNLYHI YEVNLVSEHI WCEDFLVRSF YLKNLQTNET 
RTVTQFHFLS WYDRGVPSSS RSLLDFRRKV NKCYRGRSCP IIVHCSDGAG RSGTYVLIDM 
VLNKMAKGAK EIDIAATLEH LRDQRPGMVQ TKEQFEFALT AVAEEVNAIL KALPQ

Genular Protein ID: 582422153

Symbol: E7EM83_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EM83

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 5 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

Sequence Information:

  • Length: 977
  • Mass: 106989
  • Checksum: D3297D96062D85F1
  • Sequence:
    • MGPPLPLLLL LLLLLPPRVL PAAPSSVPRG RQLPGRLGCL LEEGLCGASE ACVNGFTWQD 
DYTQYVMDQE LADLPKTYLR RPEASSPARP SKHSVGSERR YSREGGAALA NALRRHLPFL 
EALSQAPASD VLARTHTAQD RPPAEGDDRF SESILTYVAH TSALTYPPGS RTQLREDLLP 
RTLGQLQPDE LSPKVDSGVD RHHLMAALSA YAAQRPPAPP GEGSLEPQYL LRAPSRMPRP 
LLAPAAPQKW PSPLGDSEDP SSTGDGARIH TLLKDLQRQP AEVRGLSGLE LDGMAELMAG 
LMQGVDHGVA RGSPGRAALG ESGEQADGPK ATLRGDSFPD DGVQDDDDRL YQEVHRLSAT 
LGGLLQDHGS RLLPGALPFA RPLDMERKKS EHPESSLSSE EETAGVENVK SQTYSKDLLG 
QQPHSEPGAA AFGELQNQMP GPSKEEQSLP AGAQEALSDG LQLEVQPSEE EARGYIVTDR 
DPLRPEEGRR LVEDVARLLQ VPSSAFADVE VLGPAVTFKV SANVQNVTTE DVEKATVDNK 
DKLEETSGLK ILQTGVGSKS KLKFLPPQAE QEDSTKFIAL TLVSLACILG VLLASGLIYC 
LRHSSQHRLK EKLSGLGGDP GADATAAYQE LCRQRMATRP PDRPEGPHTS RISSVSSQFS 
DGPIPSPSAR SSASSWSEEP VQSNMDISTG HMILSYMEDH LKNKNRLEKE WEALCAYQAE 
PNSSFVAQRE ENVPKNRSLA VLTYDHSRVL LKAENSHSHS DYINASPIMD HDPRNPAYIA 
TQGPLPATVA DFWQMVWESG CVVIVMLTPL AENGVRQCYH YWPDEGSNLY HIYEVNLVSE 
HIWCEDFLVR SFYLKNLQTN ETRTVTQFHF LSWYDRGVPS SSRSLLDFRR KVNKCYRGRS 
CPIIVHCSDG AGRSGTYVLI DMVLNKMAKG AKEIDIAATL EHLRDQRPGM VQTKEQFEFA 
LTAVAEEVNA ILKALPQ

Genular Protein ID: 469212448

Symbol: I6L9F8_HUMAN

Name: N/A

UniProtKB Accession Codes:

I6L9F8

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 2 RefSeq 3 SAM 3 SMART 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 633
  • Mass: 68000
  • Checksum: 717535877EA419EF
  • Sequence:
    • MGPPLPLLLL LLLLLPPRVL PAAPSSVPRG RQLPGRLGCL LEEGLCGASE ACVNGFTWQD 
DYTQYVMDQE LADLPKTYLR RPEASSPARP SKHSVGSERR YSREGGAALA NALRRHLPFL 
EALSQAPASD VLARTHTAQD RPPAEGDDRF SESILTYVAH TSALTYPPGP RTQLREDLLP 
RTLGQLQPDE LSPKVDSGVD RHHLMAALSA YAAQRPPAPP GEGSLEPQYL LRAPSRMPRP 
LLAPAAPQKW PSPLGDSEDP SSTGDGARIH TLLKDLQRQP AEVRGLSGLE LDGMAELMAG 
LMQGVDHGVA RGSPGRAALG ESGEQADGPK ATLRGDSFPD DGVQDDDDRL YQEVHRLSAT 
LGGLLQDHGS RLLPGALTFA RPLDMERKKS EHPESSLSSE EETAGVENVK SQTYSKDLLG 
QQPHSEPGAA AFGELQNQMP GPSKEEQSLP AGAQEALSDG LQLEVQPSEE EARGYIVTDR 
DPLRPEEGRR LVEDVARLLQ VPSSAFADVE VLGPAVTFKV SANVQNVTTE DVEKATVDNK 
DKLEETSGLK ILQTGVGSKS KLKFLPPQAE QEDSTKFIAL TLVSLACILG VLLASGLIYC 
LRHSSQHRLK EKLSGLGGDP GADATAAYQE LCR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.