Details for: PCYT2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 102.0282
Cell Significance Index: -15.8700 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 65.4462
Cell Significance Index: -16.6000 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 37.1440
Cell Significance Index: -15.0900 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 34.9349
Cell Significance Index: -17.9700 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 27.2793
Cell Significance Index: -18.3100 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 16.0357
Cell Significance Index: -15.3100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 14.0151
Cell Significance Index: -17.2800 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.0880
Cell Significance Index: -13.6300 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.4906
Cell Significance Index: -17.7200 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 3.9362
Cell Significance Index: -12.0900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.5719
Cell Significance Index: 1419.3200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.4841
Cell Significance Index: 161.4200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.3914
Cell Significance Index: 137.6500 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.1679
Cell Significance Index: 33.6500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 1.0219
Cell Significance Index: 9.4100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.7882
Cell Significance Index: 156.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.7561
Cell Significance Index: 16.3800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.6869
Cell Significance Index: 35.6800 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.6380
Cell Significance Index: 44.1200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.5564
Cell Significance Index: 25.9400 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5035
Cell Significance Index: 90.7700 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4218
Cell Significance Index: 19.1200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3811
Cell Significance Index: 208.1200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3684
Cell Significance Index: 45.3000 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 0.3543
Cell Significance Index: 22.8600 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2571
Cell Significance Index: 48.9300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 0.2356
Cell Significance Index: 12.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2067
Cell Significance Index: 41.4700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.1957
Cell Significance Index: 5.2500 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.1915
Cell Significance Index: 132.4300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.1906
Cell Significance Index: 4.0600 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.1696
Cell Significance Index: 4.4600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.1474
Cell Significance Index: 20.2400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.1430
Cell Significance Index: 6.7200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1329
Cell Significance Index: 4.6700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.1186
Cell Significance Index: 3.8000 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1077
Cell Significance Index: 47.6000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0738
Cell Significance Index: 26.4700 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0605
Cell Significance Index: 7.7500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0462
Cell Significance Index: 1.2900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0457
Cell Significance Index: 7.4300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.0371
Cell Significance Index: 1.0100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0309
Cell Significance Index: 23.3800 - Cell Name: peg cell (CL4033014)
Fold Change: 0.0303
Cell Significance Index: 0.7000 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0250
Cell Significance Index: 3.2300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 0.0208
Cell Significance Index: 1.4700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0207
Cell Significance Index: 15.2000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.0066
Cell Significance Index: 0.4900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 0.0064
Cell Significance Index: 0.1700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0043
Cell Significance Index: -8.1600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0082
Cell Significance Index: -15.0500 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0110
Cell Significance Index: -16.9900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0132
Cell Significance Index: -18.0000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0155
Cell Significance Index: -1.8300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0172
Cell Significance Index: -10.9100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0179
Cell Significance Index: -3.0500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0212
Cell Significance Index: -15.7000 - Cell Name: hepatoblast (CL0005026)
Fold Change: -0.0220
Cell Significance Index: -0.3700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0228
Cell Significance Index: -1.1900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0301
Cell Significance Index: -16.9700 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: -0.0318
Cell Significance Index: -0.5400 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0319
Cell Significance Index: -19.9000 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0364
Cell Significance Index: -16.5100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0373
Cell Significance Index: -3.8100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0452
Cell Significance Index: -2.8500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0483
Cell Significance Index: -5.6300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0512
Cell Significance Index: -14.7300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0751
Cell Significance Index: -1.0300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0814
Cell Significance Index: -11.8300 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0841
Cell Significance Index: -9.6400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0875
Cell Significance Index: -6.9300 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0946
Cell Significance Index: -19.9200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1246
Cell Significance Index: -3.6600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.1361
Cell Significance Index: -3.8900 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.1395
Cell Significance Index: -9.3800 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1433
Cell Significance Index: -3.0000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.1477
Cell Significance Index: -3.9500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1488
Cell Significance Index: -11.4200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.1596
Cell Significance Index: -5.5500 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1691
Cell Significance Index: -17.6100 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1733
Cell Significance Index: -2.9000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1824
Cell Significance Index: -11.1800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.1874
Cell Significance Index: -1.9400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.2016
Cell Significance Index: -2.9800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.2271
Cell Significance Index: -13.9600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.2290
Cell Significance Index: -5.8500 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.2865
Cell Significance Index: -8.4400 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.2990
Cell Significance Index: -16.7800 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.3384
Cell Significance Index: -7.0200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.3497
Cell Significance Index: -15.4700 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.3607
Cell Significance Index: -3.0300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.3687
Cell Significance Index: -7.8800 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.3800
Cell Significance Index: -5.4500 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3856
Cell Significance Index: -13.5100 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.3887
Cell Significance Index: -14.2700 - Cell Name: epidermal cell (CL0000362)
Fold Change: -0.4081
Cell Significance Index: -0.9200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.4161
Cell Significance Index: -15.7600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.4163
Cell Significance Index: -13.2600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.4186
Cell Significance Index: -10.7600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 494707543
Symbol: PCY2_HUMAN
Name: Ethanolamine-phosphate cytidylyltransferase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9083101
Title: Cloning of a human cDNA for CTP-phosphoethanolamine cytidylyltransferase by complementation in vivo of a yeast mutant.
PubMed ID: 9083101
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 31637422
Title: Mutations in PCYT2 disrupt etherlipid biosynthesis and cause a complex hereditary spastic paraplegia.
PubMed ID: 31637422
DOI: 10.1093/brain/awz291
Sequence Information:
- Length: 389
- Mass: 43835
- Checksum: 13FE8EAEB7FFAF7F
- Sequence:
MIRNGRGAAG GAEQPGPGGR RAVRVWCDGC YDMVHYGHSN QLRQARAMGD YLIVGVHTDE EIAKHKGPPV FTQEERYKMV QAIKWVDEVV PAAPYVTTLE TLDKYNCDFC VHGNDITLTV DGRDTYEEVK QAGRYRECKR TQGVSTTDLV GRMLLVTKAH HSSQEMSSEY REYADSFGKC PGGRNPWTGV SQFLQTSQKI IQFASGKEPQ PGETVIYVAG AFDLFHIGHV DFLEKVHRLA ERPYIIAGLH FDQEVNHYKG KNYPIMNLHE RTLSVLACRY VSEVVIGAPY AVTAELLSHF KVDLVCHGKT EIIPDRDGSD PYQEPKRRGI FRQIDSGSNL TTDLIVQRII TNRLEYEARN QKKEAKELAF LEAARQQAAQ PLGERDGDF
Genular Protein ID: 2250917340
Symbol: I3L1R7_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 367
- Mass: 41396
- Checksum: DFF148A52B885173
- Sequence:
MIRNGRGAAG GAEQPGPGGR RAVRVWCDGC YDMVHYGHSN QLRQARAMGD YLIVGVHTDE EIAKHKGPPV FTQEERYKMV QAIKWVDEVV PAAPYVTTLE TLDKYNCDFC VHGNDITLTV DGRDTYEEVK QAGRYRECKR TQGVSTTDLV GRMLLVTKAH HSSQEMSSEY REYADSFGKC PGGRNPWTGV SQFLQTSQKI IQFASGKEPQ PGETVIYVAG AFDLFHIGHV DFLEKVHRLA ERPYIIAGLH FDQEVNHYKG KNYPIMNLHE RTLSVLACRY VSEVVIGAPY AVTAELLSHF KEPKRRGIFR QIDSGSNLTT DLIVQRIITN RLEYEARNQK KEAKELAFLE AARQQAAQPL GERDGDF
Genular Protein ID: 733447149
Symbol: B3KSC8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
Sequence Information:
- Length: 311
- Mass: 35170
- Checksum: 13FE1465378CDDFC
- Sequence:
MVQAIKWVGE VVPAAPYVTT LETLDKYNCD FCVHGNDITL TVDGRDTYEE VKQAGRYREC RRTQGVSTTD LVGRMLLVTK AHHSSQEMSS EYREYADSFG KCPGGRNPWT GVSQFLQTSQ KIIQFASGKE PQPGETVIYV AGAFDLFHIG HVDFLEKVHR LAERPYIIAG LHFDQEVNHY KGKNYPIMNL HERTLSVLAC RYVSEVVIGA PYAVTAELLS HFKVDLVCHG KTEIIPDRDG SDPYQEPKRR GIFRQIDSGS NLTTDLIVQR IITNRLEYEA RNQKKEAKEL AFLEAARQQA AQPLGERDGD F
Genular Protein ID: 188662217
Symbol: B7Z4W6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 357
- Mass: 40532
- Checksum: D04A16069C178044
- Sequence:
MVHYGHSNQL RQARAMGDYL IVGVHTDEEI AKHKGPPVFT QEERYKMVQA IKWVDEVVPA APYVITLETL DKYNCDFCVH GNDITLTVDG RDTYEEVKQA GRYRECKRTQ GVSTTDLVGR MLLVTKAHHS SQEMSSEYRE YADSFGKCPG GRNPWTGVSQ FLQTSQKIIQ FASGKEPQPG ETVIYVAGAF DLFHIGHVDF LEKVHRLAER PYIIAGLHFD QEVNHYKGKN YPIMNLHERT LSVLACRYVS EVVIGAPYAV TAELLSHFKV DLVCHGKTEI IPDRDGSDPY QEPKRRGIFR QIDSGSNLTT DLIVQRIITN RLEYEARNQK KEAKELAFLE AARQQAAQPL GERDGDF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.