Details for: RAD52

Gene ID: 5893

Symbol: RAD52

Ensembl ID: ENSG00000002016

Description: RAD52 homolog, DNA repair protein

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 121.9581
    Cell Significance Index: -18.9700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 74.9872
    Cell Significance Index: -19.0200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 37.3163
    Cell Significance Index: -15.1600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 15.8577
    Cell Significance Index: -15.1400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.6616
    Cell Significance Index: -19.3100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.0664
    Cell Significance Index: -18.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.9315
    Cell Significance Index: -19.4600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.5509
    Cell Significance Index: -9.9600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.2428
    Cell Significance Index: 249.3100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.2037
    Cell Significance Index: 30.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0485
    Cell Significance Index: 208.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8409
    Cell Significance Index: 64.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7148
    Cell Significance Index: 70.7100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6320
    Cell Significance Index: 102.7900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6291
    Cell Significance Index: 18.1300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.5736
    Cell Significance Index: 26.0000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.5628
    Cell Significance Index: 31.5800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.5387
    Cell Significance Index: 193.2200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5303
    Cell Significance Index: 478.8300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4958
    Cell Significance Index: 21.9300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4880
    Cell Significance Index: 18.4800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.4488
    Cell Significance Index: 65.2400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.3568
    Cell Significance Index: 246.7900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3536
    Cell Significance Index: 7.6600
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3351
    Cell Significance Index: 6.5400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3304
    Cell Significance Index: 20.3100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3150
    Cell Significance Index: 34.2700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.2916
    Cell Significance Index: 8.1500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.2428
    Cell Significance Index: 6.0700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2400
    Cell Significance Index: 2.2100
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.2312
    Cell Significance Index: 3.8100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.2060
    Cell Significance Index: 2.5600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1999
    Cell Significance Index: 12.0000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.1967
    Cell Significance Index: 4.2100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1834
    Cell Significance Index: 34.9100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.1799
    Cell Significance Index: 4.3900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1668
    Cell Significance Index: 4.0000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1661
    Cell Significance Index: 11.1700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.1549
    Cell Significance Index: 4.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.1331
    Cell Significance Index: 15.5100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1075
    Cell Significance Index: 7.4400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1002
    Cell Significance Index: 2.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0726
    Cell Significance Index: 2.5500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0713
    Cell Significance Index: 12.8500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0647
    Cell Significance Index: 121.8900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0614
    Cell Significance Index: 7.5500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0562
    Cell Significance Index: 103.6700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0544
    Cell Significance Index: 83.7700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0263
    Cell Significance Index: 0.4500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0260
    Cell Significance Index: 16.5300
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.0230
    Cell Significance Index: 0.3100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0224
    Cell Significance Index: 30.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0194
    Cell Significance Index: 8.7900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0142
    Cell Significance Index: 7.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0104
    Cell Significance Index: 4.6200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.0100
    Cell Significance Index: 0.5200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.0003
    Cell Significance Index: 0.0000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0183
    Cell Significance Index: -0.9500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0201
    Cell Significance Index: -14.7300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0213
    Cell Significance Index: -15.7600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0257
    Cell Significance Index: -19.4500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0258
    Cell Significance Index: -3.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0311
    Cell Significance Index: -17.5500
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0337
    Cell Significance Index: -0.7000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0344
    Cell Significance Index: -21.4600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0442
    Cell Significance Index: -5.6700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0515
    Cell Significance Index: -14.8100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0534
    Cell Significance Index: -6.3000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0667
    Cell Significance Index: -1.4200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0669
    Cell Significance Index: -11.4300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0969
    Cell Significance Index: -20.4000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0974
    Cell Significance Index: -2.6000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1034
    Cell Significance Index: -10.5600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.1078
    Cell Significance Index: -2.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1100
    Cell Significance Index: -6.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1208
    Cell Significance Index: -12.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1225
    Cell Significance Index: -14.0400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1236
    Cell Significance Index: -1.7700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1313
    Cell Significance Index: -16.9700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1316
    Cell Significance Index: -8.4900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1356
    Cell Significance Index: -6.3200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1442
    Cell Significance Index: -3.0600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1604
    Cell Significance Index: -2.0000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1607
    Cell Significance Index: -9.8500
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1632
    Cell Significance Index: -2.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1707
    Cell Significance Index: -12.0700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1745
    Cell Significance Index: -5.5900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1770
    Cell Significance Index: -8.3200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1889
    Cell Significance Index: -9.9200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1914
    Cell Significance Index: -3.7900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2172
    Cell Significance Index: -17.2100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2216
    Cell Significance Index: -16.5200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2259
    Cell Significance Index: -7.2000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.2490
    Cell Significance Index: -5.0000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2553
    Cell Significance Index: -8.3600
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2615
    Cell Significance Index: -3.3000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2698
    Cell Significance Index: -4.6700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2726
    Cell Significance Index: -5.8900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3091
    Cell Significance Index: -7.7100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3297
    Cell Significance Index: -16.6600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** RAD52 is a DNA repair protein that belongs to the PARP (Poly (ADP-ribose) polymerase) family. It is a homolog of the yeast RAD52 protein, which is essential for the repair of DNA double-strand breaks through HR and SSA pathways. RAD52 is characterized by its ability to bind to single-stranded DNA (ssDNA) and facilitate the exchange of genetic information between homologous chromosomes. This process is crucial for maintaining genomic stability and preventing mutations that can lead to cancer. **Pathways and Functions** RAD52 is involved in several DNA repair pathways, including: 1. **Homologous Recombination (HR)**: RAD52 facilitates the exchange of genetic information between homologous chromosomes, allowing for the repair of DNA double-strand breaks. 2. **Single-Strand Annealing (SSA)**: RAD52 is involved in the annealing of single-stranded DNA ends, allowing for the repair of DNA double-strand breaks. 3. **Non-Homologous End Joining (NHEJ)**: RAD52 can also participate in the repair of DNA double-strand breaks through NHEJ, although its role is less well understood. 4. **DNA Recombination**: RAD52 is involved in the recombination of DNA strands, allowing for the repair of DNA double-strand breaks. RAD52's functions can be summarized as follows: * **DNA binding**: RAD52 binds to single-stranded DNA (ssDNA) and facilitates the exchange of genetic information between homologous chromosomes. * **DNA repair**: RAD52 is involved in the repair of DNA double-strand breaks through HR, SSA, and NHEJ pathways. * **Genomic stability**: RAD52 helps maintain genomic stability by preventing mutations that can lead to cancer and other diseases. **Clinical Significance** RAD52 is an important gene in the context of cancer and other diseases. Mutations in RAD52 have been associated with an increased risk of cancer, including breast, ovarian, and colon cancer. RAD52's role in DNA repair also makes it an attractive target for therapeutic interventions aimed at preventing DNA damage and promoting cancer prevention. In addition to its role in cancer, RAD52's dysregulation has also been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease. RAD52's expression profile in neurons and astrocytes suggests its importance in maintaining neural function and promoting neuroprotection. In conclusion, RAD52 is a crucial gene involved in DNA repair and genomic stability. Its dysregulation has been implicated in various diseases, including cancer and neurological disorders. Further research on RAD52's role in DNA repair and its potential therapeutic applications is needed to fully understand its significance in human health and disease.

Genular Protein ID: 3581959890

Symbol: RAD52_HUMAN

Name: DNA repair protein RAD52 homolog

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 7774919

Title: The human and mouse homologs of the yeast RAD52 gene: cDNA cloning, sequence analysis, assignment to human chromosome 12p12.2-p13, and mRNA expression in mouse tissues.

PubMed ID: 7774919

DOI: 10.1016/0888-7543(95)80126-7

PubMed ID: 7526206

Title: Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination.

PubMed ID: 7526206

DOI: 10.1016/0921-8777(94)90040-x

PubMed ID: 7797537

Title: Expression of human RAD52 confers resistance to ionizing radiation in mammalian cells.

PubMed ID: 7797537

DOI: 10.1074/jbc.270.26.15467

PubMed ID: 10673031

Title: Identification of novel isoforms of human RAD52.

PubMed ID: 10673031

DOI: 10.1016/s0167-4781(99)00214-6

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 8702565

Title: Physical interaction between human RAD52 and RPA is required for homologous recombination in mammalian cells.

PubMed ID: 8702565

DOI: 10.1074/jbc.271.31.18996

PubMed ID: 12379650

Title: Regulation of ionizing radiation-induced Rad52 nuclear foci formation by c-Abl-mediated phosphorylation.

PubMed ID: 12379650

DOI: 10.1074/jbc.m208151200

PubMed ID: 17525332

Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

PubMed ID: 17525332

DOI: 10.1126/science.1140321

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 31400850

Title: RAD51AP1 is an essential mediator of alternative lengthening of telomeres.

PubMed ID: 31400850

DOI: 10.1016/j.molcel.2019.06.043

PubMed ID: 31585101

Title: RAD51AP1 is an essential mediator of alternative lengthening of telomeres.

PubMed ID: 31585101

DOI: 10.1016/j.molcel.2019.08.009

PubMed ID: 12191481

Title: Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form.

PubMed ID: 12191481

DOI: 10.1016/s1097-2765(02)00587-7

PubMed ID: 12370410

Title: Structure of the single-strand annealing domain of human RAD52 protein.

PubMed ID: 12370410

DOI: 10.1073/pnas.212449899

Sequence Information:

  • Length: 418
  • Mass: 46169
  • Checksum: 7E1BBCAF0B9CD4AF
  • Sequence:
  • MSGTEEAILG GRDSHPAAGG GSVLCFGQCQ YTAEEYQAIQ KALRQRLGPE YISSRMAGGG 
    QKVCYIEGHR VINLANEMFG YNGWAHSITQ QNVDFVDLNN GKFYVGVCAF VRVQLKDGSY 
    HEDVGYGVSE GLKSKALSLE KARKEAVTDG LKRALRSFGN ALGNCILDKD YLRSLNKLPR 
    QLPLEVDLTK AKRQDLEPSV EEARYNSCRP NMALGHPQLQ QVTSPSRPSH AVIPADQDCS 
    SRSLSSSAVE SEATHQRKLR QKQLQQQFRE RMEKQQVRVS TPSAEKSEAA PPAPPVTHST 
    PVTVSEPLLE KDFLAGVTQE LIKTLEDNSE KWAVTPDAGD GVVKPSSRAD PAQTSDTLAL 
    NNQMVTQNRT PHSVCHQKPQ AKSGSWDLQT YSADQRTTGN WESHRKSQDM KKRKYDPS

Genular Protein ID: 1329042140

Symbol: B7Z2G8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 301
  • Mass: 32420
  • Checksum: B986AA1ED19EEC92
  • Sequence:
  • MSGTEEAILG GRDSHPAAGG GSVLCFGQCQ YTAEEYQAIQ TALRQRLGPE YISSRMAGGG 
    QKVCYIEGHR VINLANEMFG YNGWAHSITQ QNVDFVDLNN GKFYVGVCAS VRVQLKDGSY 
    HEDVGYGVSE GLKSKALSLE KARKEAVTDG LKRALRSFGN ALGNCILDKD YLRSLNKLPR 
    QLPLEVDLTK AKRQDLEPSV EEARYNSCRP NMALGHPQLQ QVTSPSRPSH AVIPADQDCS 
    SRSRGCCSGA RPRRRPLMQK PELIRRGERG HAPAEAPAEA AAAAVPGADG EAAGSSLHAV 
    S

Genular Protein ID: 2033282098

Symbol: B7Z5Q6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 341
  • Mass: 37897
  • Checksum: AFF5768487F527B1
  • Sequence:
  • MFGYNGWAHS ITQQNVDFVD LNNGKFYVGV CAFVRVQLKD GSYHEDVGYG VSEGLKSKAL 
    SLEKARKEAV TDGLKRALRS FGNALGNCIL GKDYLRSLNK LPRQLPLEVD LTKAKRQDLE 
    PSVEEARYNS CRPNMALGHP QLQQVTSPSR PSHAVIPADQ DCSSRSLSSS AVESEATHQR 
    KLRQKQLQQQ FRERMEKQQV RVSTPSAEKS EAAPPAPPVT HSTPVTVSEP LLEKDFLAGV 
    TQELIKTLED NSEKWAVTPD AGDGVVKPSS RADPAQTSDT LALNNQMVTQ NRTPHSVCHQ 
    KPQAKSGSWD LQTYSADQRT TGNWESHRKS QDMKKRKYDP S

Genular Protein ID: 4166471214

Symbol: F5GX32_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 301
  • Mass: 32508
  • Checksum: EA351B13B81220EB
  • Sequence:
  • MSGTEEAILG GRDSHPAAGG GSVLCFGQCQ YTAEEYQAIQ KALRQRLGPE YISSRMAGGG 
    QKVCYIEGHR VINLANEMFG YNGWAHSITQ QNVDFVDLNN GKFYVGVCAF VRVQLKDGSY 
    HEDVGYGVSE GLKSKALSLE KARKEAVTDG LKRALRSFGN ALGNCILDKD YLRSLNKLPR 
    QLPLEVDLTK AKRQDLEPSV EEARYNSCRP NMALGHPQLQ QVTSPSRPSH AVIPADQDCS 
    SRSRGCCSGA RPRRRPLMQK PELIRRGERG HAPAEAPAEA AAAAVPGADG EAAGSSLHAV 
    S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.