Details for: RXRB

Gene ID: 6257

Symbol: RXRB

Ensembl ID: ENSG00000204231

Description: retinoid X receptor beta

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 122.9224
    Cell Significance Index: -19.1200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 72.0697
    Cell Significance Index: -18.2800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 45.5007
    Cell Significance Index: -18.4900
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 41.3698
    Cell Significance Index: -21.2800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 19.5760
    Cell Significance Index: -18.6900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 16.5862
    Cell Significance Index: -20.4500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.1635
    Cell Significance Index: -19.1900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.2559
    Cell Significance Index: -20.7400
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.9423
    Cell Significance Index: -15.1800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.2213
    Cell Significance Index: -7.0500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6370
    Cell Significance Index: 161.9400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.2964
    Cell Significance Index: 1170.5400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.2181
    Cell Significance Index: 141.9600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.0760
    Cell Significance Index: 14.6800
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.6895
    Cell Significance Index: 4.5000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.6826
    Cell Significance Index: 35.8400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4470
    Cell Significance Index: 30.9100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4158
    Cell Significance Index: 11.9800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4119
    Cell Significance Index: 82.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4004
    Cell Significance Index: 11.1900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3863
    Cell Significance Index: 8.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3189
    Cell Significance Index: 43.8000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3186
    Cell Significance Index: 14.4400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3150
    Cell Significance Index: 10.9500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3141
    Cell Significance Index: 16.3600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3125
    Cell Significance Index: 14.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3111
    Cell Significance Index: 61.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.3071
    Cell Significance Index: 8.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2693
    Cell Significance Index: 48.5500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2495
    Cell Significance Index: 172.5300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.2446
    Cell Significance Index: 5.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.2387
    Cell Significance Index: 30.6000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2119
    Cell Significance Index: 115.7400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1837
    Cell Significance Index: 11.5800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1818
    Cell Significance Index: 80.3900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1754
    Cell Significance Index: 9.1100
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1714
    Cell Significance Index: 32.6200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1668
    Cell Significance Index: 20.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1628
    Cell Significance Index: 7.6500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1590
    Cell Significance Index: 57.0400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1483
    Cell Significance Index: 9.5700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0962
    Cell Significance Index: 2.5300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0960
    Cell Significance Index: 12.4000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0821
    Cell Significance Index: 9.6800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0671
    Cell Significance Index: 0.7000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0642
    Cell Significance Index: 3.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0484
    Cell Significance Index: 3.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0299
    Cell Significance Index: 5.1000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0114
    Cell Significance Index: 21.4500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0033
    Cell Significance Index: 0.1100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0021
    Cell Significance Index: 3.8200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0054
    Cell Significance Index: -8.2700
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0067
    Cell Significance Index: -4.2300
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.0078
    Cell Significance Index: -0.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0101
    Cell Significance Index: -0.7500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0116
    Cell Significance Index: -15.7500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0131
    Cell Significance Index: -9.9200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0143
    Cell Significance Index: -10.4900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0197
    Cell Significance Index: -0.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0206
    Cell Significance Index: -15.2700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0257
    Cell Significance Index: -11.6600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0306
    Cell Significance Index: -4.4600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0332
    Cell Significance Index: -2.5500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0335
    Cell Significance Index: -18.9100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0375
    Cell Significance Index: -3.8300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0428
    Cell Significance Index: -26.7200
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0614
    Cell Significance Index: -7.0400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0742
    Cell Significance Index: -21.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0850
    Cell Significance Index: -2.2700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0915
    Cell Significance Index: -1.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1083
    Cell Significance Index: -22.8100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.1301
    Cell Significance Index: -3.7300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1348
    Cell Significance Index: -1.4700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1350
    Cell Significance Index: -3.4500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1468
    Cell Significance Index: -8.2400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.1542
    Cell Significance Index: -2.3100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1867
    Cell Significance Index: -19.4500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1972
    Cell Significance Index: -3.3800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.2052
    Cell Significance Index: -2.8800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2182
    Cell Significance Index: -5.6100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.2276
    Cell Significance Index: -6.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2299
    Cell Significance Index: -18.2100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2347
    Cell Significance Index: -10.3800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.2409
    Cell Significance Index: -5.1300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2522
    Cell Significance Index: -15.4600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2925
    Cell Significance Index: -11.0800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.2995
    Cell Significance Index: -3.5700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3056
    Cell Significance Index: -8.1800
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3068
    Cell Significance Index: -12.5700
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: -0.3333
    Cell Significance Index: -3.4800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3366
    Cell Significance Index: -4.9700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3633
    Cell Significance Index: -11.5700
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.3717
    Cell Significance Index: -4.7600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3734
    Cell Significance Index: -13.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3751
    Cell Significance Index: -12.2800
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3892
    Cell Significance Index: -8.2600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4128
    Cell Significance Index: -12.1600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.4137
    Cell Significance Index: -7.3100
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.4157
    Cell Significance Index: -8.8900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.4271
    Cell Significance Index: -5.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Sequence-specific DNA binding**: RXRB binds to specific DNA sequences, known as retinoic acid-responsive elements (RAREs), to regulate gene expression. 2. **Transcriptional activation**: RXRB acts as a transcriptional activator, promoting the expression of target genes involved in cell differentiation, development, and metabolism. 3. **Interactions with other transcription factors**: RXRB interacts with other transcription factors, such as PPARα and NR1H2/NR1H3, to modulate gene expression in response to different ligands. 4. **Expression in various cell types**: RXRB is highly expressed in cells involved in development, differentiation, and homeostasis, including pulmonary interstitial fibroblasts, extravillous trophoblasts, and intestinal epithelial cells. 5. **Involvement in metabolic pathways**: RXRB regulates gene expression in response to lipid metabolites, bile acids, and retinoic acid, influencing lipid metabolism, gluconeogenesis, lipogenesis, and cholesterol homeostasis. **Pathways and Functions:** 1. **Hormone-mediated signaling pathway**: RXRB interacts with retinoic acid, bile acids, and lipid metabolites to regulate gene expression in response to hormone signals. 2. **Metabolism of lipids**: RXRB regulates gene expression in response to lipid metabolites, influencing lipid metabolism, lipogenesis, and cholesterol homeostasis. 3. **Gene expression (transcription)**: RXRB acts as a transcriptional activator, promoting the expression of target genes involved in cell differentiation, development, and metabolism. 4. **Chromatin remodeling**: RXRB interacts with chromatin remodeling complexes to regulate gene expression and epigenetic modifications. 5. **Signaling by nuclear receptors**: RXRB is a member of the nuclear receptor superfamily and interacts with other nuclear receptors to modulate gene expression in response to different ligands. **Clinical Significance:** 1. **Metabolic disorders**: RXRB dysregulation has been implicated in metabolic disorders, including obesity, diabetes, and dyslipidemia. 2. **Cancer**: RXRB is overexpressed in various types of cancer, including breast, lung, and colon cancer, and is involved in cancer progression and metastasis. 3. **Cardiovascular diseases**: RXRB regulates gene expression in response to lipid metabolites and bile acids, influencing cholesterol homeostasis and cardiovascular disease risk. 4. **Neurological disorders**: RXRB is involved in the regulation of gene expression in response to retinoic acid and other ligands, influencing neurological disorders, such as autism and Alzheimer's disease. In conclusion, RXRB is a critical regulator of gene expression and metabolism in humans, playing a pivotal role in various biological processes, including development, differentiation, and homeostasis. Dysregulation of RXRB has been implicated in various diseases, highlighting the importance of this gene in maintaining human health.

Genular Protein ID: 3551175965

Symbol: RXRB_HUMAN

Name: Retinoic acid receptor RXR-beta

UniProtKB Accession Codes:

P28702 P28703 Q59G65 Q5JP92 Q5STQ1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 ComplexPortal 3 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 15 DrugCentral 1 EMBL 15 Ensembl 12 EvolutionaryTrace 1 ExpressionAtlas 1 GO 23 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MoonDB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 1 PRINTS 3 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 9 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1310259

Title: Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently.

PubMed ID: 1310259

DOI: 10.1016/0092-8674(92)90478-u

PubMed ID: 1330328

Title:

PubMed ID: 1330328

PubMed ID: 1315958

Title: Isolation of a full-length cDNA clone encoding a N-terminally variant form of the human retinoid X receptor beta.

PubMed ID: 1315958

DOI: 10.1093/nar/20.7.1801

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8381386

Title: Cloning and chromosome mapping of human retinoid X receptor beta: selective amino acid sequence conservation of a nuclear hormone receptor in mammals.

PubMed ID: 8381386

DOI: 10.1007/bf00217449

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 24129315

Title: Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.

PubMed ID: 24129315

DOI: 10.1074/mcp.o113.027870

PubMed ID: 26463675

Title: Retinoid X receptor activation reverses age-related deficiencies in myelin debris phagocytosis and remyelination.

PubMed ID: 26463675

DOI: 10.1093/brain/awv289

PubMed ID: 28167758

Title: MicroRNA-10a is crucial for endothelial response to different flow patterns via interaction of retinoid acid receptors and histone deacetylases.

PubMed ID: 28167758

DOI: 10.1073/pnas.1621425114

PubMed ID: 11782480

Title: The structural basis for the specificity of retinoid-X receptor-selective agonists: new insights into the role of helix H12.

PubMed ID: 11782480

DOI: 10.1074/jbc.m110869200

PubMed ID: 12970175

Title: Crystal structure of the heterodimeric complex of LXRalpha and RXRbeta ligand-binding domains in a fully agonistic conformation.

PubMed ID: 12970175

DOI: 10.1093/emboj/cdg456

Sequence Information:

  • Length: 533
  • Mass: 56922
  • Checksum: D0069FE93AC16A04
  • Sequence:
    • MSWAARPPFL PQRHAAGQCG PVGVRKEMHC GVASRWRRRR PWLDPAAAAA AAVAGGEQQT 
PEPEPGEAGR DGMGDSGRDS RSPDSSSPNP LPQGVPPPSP PGPPLPPSTA PSLGGSGAPP 
PPPMPPPPLG SPFPVISSSM GSPGLPPPAP PGFSGPVSSP QINSTVSLPG GGSGPPEDVK 
PPVLGVRGLH CPPPPGGPGA GKRLCAICGD RSSGKHYGVY SCEGCKGFFK RTIRKDLTYS 
CRDNKDCTVD KRQRNRCQYC RYQKCLATGM KREAVQEERQ RGKDKDGDGE GAGGAPEEMP 
VDRILEAELA VEQKSDQGVE GPGGTGGSGS SPNDPVTNIC QAADKQLFTL VEWAKRIPHF 
SSLPLDDQVI LLRAGWNELL IASFSHRSID VRDGILLATG LHVHRNSAHS AGVGAIFDRV 
LTELVSKMRD MRMDKTELGC LRAIILFNPD AKGLSNPSEV EVLREKVYAS LETYCKQKYP 
EQQGRFAKLL LRLPALRSIG LKCLEHLFFF KLIGDTPIDT FLMEMLEAPH QLA

Genular Protein ID: 1123155480

Symbol: A0A0G2JKR7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0G2JKR7

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 Ensembl 2 GO 4 Gene3D 2 HGNC 1 InterPro 7 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2

Citations:

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 347
  • Mass: 38516
  • Checksum: 616BB2D8BA04B244
  • Sequence:
    • MRECGGGPGA GKRLCAICGD RSSGKHYGVY SCEGCKGFFK RTIRKDLTYS CRDNKDCTVD 
KRQRNRCQYC RYQKCLATGM KREAVQEERQ RGKDKDGDGE GAGGAPEEMP VDRILEAELA 
VEQKSDQGVE GPGGTGGSGS SPNDPVTNIC QAADKQLFTL VEWAKRIPHF SSLPLDDQVI 
LLRAGWNELL IASFSHRSID VRDGILLATG LHVHRNSAHS AGVGAIFDRS LSRVLTELVS 
KMRDMRMDKT ELGCLRAIIL FNPDAKGLSN PSEVEVLREK VYASLETYCK QKYPEQQGRF 
AKLLLRLPAL RSIGLKCLEH LFFFKLIGDT PIDTFLMEML EAPHQLA

Genular Protein ID: 462645656

Symbol: B7Z7J5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z7J5

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 8 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 347
  • Mass: 38500
  • Checksum: 0D6BB2D8BA15F750
  • Sequence:
    • MRECGGGPGA GKRLCAICGD RSSGKHYGVY SCEGCKGFFK RTIRKDLTYS CRDNKDCTVD 
KRQRNRCQYC RYQKCLATGM KREAVQEERQ RGKDKDGDGE GAGGAPEEMP VDRILEAELA 
VEQKSDQGVE GPGGTGGSGS SPNDPVTNIC QAADKQLFTL VEWAKRIPHF SSLPLDDQVI 
LLRAGWNELL IASFSHRSID VRDGILLATG LHVHRNSAHS AGVGAIFDRS LSRVLTELVS 
KMRDMRMDKT ELGCLRAIIL FNPDAKGLSN PSEVEVLREK VYASLETYCK QKYPEQQGRF 
AKLLLRLPAP RSIGLKCLEH LFFFKLIGDT PIDTFLMEML EAPHQLA

Genular Protein ID: 2785892256

Symbol: A0A0S2Z570_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0S2Z570

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 5 ExpressionAtlas 1 GO 10 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 5 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 26871637

Title: Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.

PubMed ID: 26871637

DOI: 10.1016/j.cell.2016.01.029

Sequence Information:

  • Length: 537
  • Mass: 57365
  • Checksum: E6789FB00428DA2C
  • Sequence:
    • MSWAARPPFL PQRHAAGQCG PVGVRKEMHC GVASRWRRRR PWLDPAAAAA AAVAGGEQQT 
PEPEPGEAGR DGMGDSGRDS RSPDSSSPNP LPQGVPPPSP PGPPLPPSTA PSLGGSGAPP 
PPPMPPPPLG SPFPVISSSM GSPGLPPPAP PGFSGPVSSP QINSTVSLPG GGSGPPEDVK 
PPVLGVRGLH CPPPPGGPGA GKRLCAICGD RSSGKHYGVY SCEGCKGFFK RTIRKDLTYS 
CRDNKDCTVD KRQRNRCQYC RYQKCLATGM KREAVQEERQ RGKDKDGDGE GAGGAPEEMP 
VDRILEAELA VEQKSDQGVE GPGGTGGSGS SPNDPVTNIC QAADKQLFTL VEWAKRIPHF 
SSLPLDDQVI LLRAGWNELL IASFSHRSID VRDGILLATG LHVHRNSAHS AGVGAIFDRS 
LSRVLTELVS KMRDMRMDKT ELGCLRAIIL FNPDAKGLSN PSEVEVLREK VYASLETYCK 
QKYPEQQGRF AKLLLRLPAL RSIGLKCLEH LFFFKLIGDT PIDTFLMEML EAPHQLA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.