Details for: SALL2

Gene ID: 6297

Symbol: SALL2

Ensembl ID: ENSG00000165821

Description: spalt like transcription factor 2

Associated with

  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Eye development
    (GO:0001654)
  • Metal ion binding
    (GO:0046872)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 28.9383
    Cell Significance Index: -7.3400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 16.8120
    Cell Significance Index: -6.8300
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 7.2480
    Cell Significance Index: -6.9200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.1683
    Cell Significance Index: 46.9800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.8450
    Cell Significance Index: 44.6900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.1655
    Cell Significance Index: 37.3300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.9299
    Cell Significance Index: 176.9700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6001
    Cell Significance Index: 59.3700
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5151
    Cell Significance Index: 465.0600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4153
    Cell Significance Index: 8.8500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.3571
    Cell Significance Index: 12.4100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3225
    Cell Significance Index: 16.8000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3158
    Cell Significance Index: 51.3600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3116
    Cell Significance Index: 33.8900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.2401
    Cell Significance Index: 3.0800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.2355
    Cell Significance Index: 1.8800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2158
    Cell Significance Index: 13.6000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2130
    Cell Significance Index: 12.7900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1676
    Cell Significance Index: 8.8000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1659
    Cell Significance Index: 11.4800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.1347
    Cell Significance Index: 2.9500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.1191
    Cell Significance Index: 1.7100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1084
    Cell Significance Index: 38.8900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0950
    Cell Significance Index: 13.0400
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.0937
    Cell Significance Index: 0.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0917
    Cell Significance Index: 18.2000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0668
    Cell Significance Index: 13.4000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0602
    Cell Significance Index: 32.8500
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0573
    Cell Significance Index: 1.2000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0572
    Cell Significance Index: 0.9800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0531
    Cell Significance Index: 6.8100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0414
    Cell Significance Index: 18.3200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0381
    Cell Significance Index: 4.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0186
    Cell Significance Index: 3.3600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0067
    Cell Significance Index: 0.3500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0062
    Cell Significance Index: 0.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0059
    Cell Significance Index: 11.1300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.0019
    Cell Significance Index: 0.0500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0016
    Cell Significance Index: -1.0900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0032
    Cell Significance Index: -2.0600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0033
    Cell Significance Index: -0.1500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0046
    Cell Significance Index: -8.4800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0049
    Cell Significance Index: -7.5500
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0051
    Cell Significance Index: -0.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0056
    Cell Significance Index: -4.0800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0061
    Cell Significance Index: -8.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0066
    Cell Significance Index: -4.9600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0081
    Cell Significance Index: -6.0100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0100
    Cell Significance Index: -5.6200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0114
    Cell Significance Index: -0.6400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0120
    Cell Significance Index: -0.2000
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: -0.0141
    Cell Significance Index: -0.0800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0143
    Cell Significance Index: -6.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0143
    Cell Significance Index: -8.9300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0181
    Cell Significance Index: -1.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0207
    Cell Significance Index: -5.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0239
    Cell Significance Index: -3.4700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0280
    Cell Significance Index: -1.9800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0292
    Cell Significance Index: -3.6000
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0318
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0379
    Cell Significance Index: -6.4700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0406
    Cell Significance Index: -8.5600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0518
    Cell Significance Index: -5.9400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0522
    Cell Significance Index: -3.5100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0572
    Cell Significance Index: -7.3900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0625
    Cell Significance Index: -2.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0675
    Cell Significance Index: -6.9000
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.0685
    Cell Significance Index: -0.4300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0706
    Cell Significance Index: -8.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0740
    Cell Significance Index: -7.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0742
    Cell Significance Index: -3.2800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0752
    Cell Significance Index: -1.5600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0762
    Cell Significance Index: -5.6800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0871
    Cell Significance Index: -2.2400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0885
    Cell Significance Index: -3.3500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0912
    Cell Significance Index: -7.2200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0952
    Cell Significance Index: -2.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0988
    Cell Significance Index: -7.5800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1073
    Cell Significance Index: -3.0000
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1104
    Cell Significance Index: -1.2000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1122
    Cell Significance Index: -1.9400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1175
    Cell Significance Index: -7.5800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.1280
    Cell Significance Index: -1.7900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1343
    Cell Significance Index: -2.1300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1397
    Cell Significance Index: -6.5700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1440
    Cell Significance Index: -8.8500
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1450
    Cell Significance Index: -4.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.1648
    Cell Significance Index: -4.4900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1668
    Cell Significance Index: -3.5400
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1668
    Cell Significance Index: -2.3900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.1689
    Cell Significance Index: -2.1000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1725
    Cell Significance Index: -2.6000
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1800
    Cell Significance Index: -3.8900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1808
    Cell Significance Index: -5.1600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1823
    Cell Significance Index: -3.6600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1851
    Cell Significance Index: -6.0600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1887
    Cell Significance Index: -6.6100
  • Cell Name: thymocyte (CL0000893)
    Fold Change: -0.1915
    Cell Significance Index: -2.4200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1978
    Cell Significance Index: -6.3000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** SALL2 is a transcription factor that exhibits the following key characteristics: 1. **DNA-binding activity**: SALL2 has the ability to bind to specific DNA sequences, which allows it to regulate transcription. 2. **RNA polymerase II-specific activity**: SALL2 is a member of the Sal-like family of transcription factors, which are known to activate transcription through the recruitment of RNA polymerase II. 3. **Expression in enterocytes and goblet cells**: SALL2 is highly expressed in enterocytes and goblet cells, which are key cell types involved in the development and maintenance of the intestinal epithelium. 4. **Role in cell proliferation and differentiation**: SALL2 has been shown to regulate cell proliferation and differentiation in various cell types, including enterocytes and GABAergic interneurons. **Pathways and Functions** SALL2 is involved in several key pathways and functions, including: 1. **Eye development**: SALL2 has been shown to play a crucial role in the development of the eye, particularly in the formation of the lens and retina. 2. **Metal ion binding**: SALL2 has been shown to bind to metal ions, which is thought to play a role in its transcriptional activity. 3. **Regulation of transcription by RNA polymerase II**: SALL2 activates transcription by recruiting RNA polymerase II to specific DNA sequences. 4. **Regulation of transcription by cis-regulatory regions**: SALL2 regulates transcription by binding to specific DNA sequences within cis-regulatory regions. **Clinical Significance** SALL2 has been implicated in various diseases, including: 1. **Intestinal disorders**: SALL2 has been shown to play a role in the development of intestinal disorders, such as inflammatory bowel disease (IBD) and colorectal cancer. 2. **Neurological disorders**: SALL2 has been implicated in the development of neurological disorders, such as autism spectrum disorder and schizophrenia. 3. **Cancer**: SALL2 has been shown to be overexpressed in certain types of cancer, including colorectal cancer and ovarian cancer. In conclusion, SALL2 is a transcription factor that plays a crucial role in various cellular processes, including cell proliferation, differentiation, and survival. Its expression is highly regulated, with significant expression in enterocytes and goblet cells, and it has been implicated in the development of intestinal disorders, neurological disorders, and cancer. Further studies are needed to fully understand the role of SALL2 in human disease and to develop novel therapeutic strategies.

Genular Protein ID: 981072289

Symbol: SALL2_HUMAN

Name: Sal-like protein 2

UniProtKB Accession Codes:

Q9Y467 B2RMX6 B9EGK8 Q8N656 Q9Y4G1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 2 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 7 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 3 SIGNOR 1 SMART 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8975705

Title: Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt.

PubMed ID: 8975705

DOI: 10.1006/geno.1996.0631

PubMed ID: 9205841

Title: Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9205841

DOI: 10.1093/dnares/4.2.141

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16545361

Title: The vertebrate spalt genes in development and disease.

PubMed ID: 16545361

DOI: 10.1016/j.ydbio.2006.02.009

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 18655026

Title: Proteomic analysis of ubiquitinated proteins in normal hepatocyte cell line Chang liver cells.

PubMed ID: 18655026

DOI: 10.1002/pmic.200700887

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24412933

Title: Mutation of SALL2 causes recessive ocular coloboma in humans and mice.

PubMed ID: 24412933

DOI: 10.1093/hmg/ddt643

Sequence Information:

  • Length: 1007
  • Mass: 105399
  • Checksum: 24B7C4ADE852B96C
  • Sequence:
    • MSRRKQRKPQ QLISDCEGPS ASENGDASEE DHPQVCAKCC AQFTDPTEFL AHQNACSTDP 
PVMVIIGGQE NPNNSSASSE PRPEGHNNPQ VMDTEHSNPP DSGSSVPTDP TWGPERRGEE 
SSGHFLVAAT GTAAGGGGGL ILASPKLGAT PLPPESTPAP PPPPPPPPPP GVGSGHLNIP 
LILEELRVLQ QRQIHQMQMT EQICRQVLLL GSLGQTVGAP ASPSELPGTG TASSTKPLLP 
LFSPIKPVQT SKTLASSSSS SSSSSGAETP KQAFFHLYHP LGSQHPFSAG GVGRSHKPTP 
APSPALPGST DQLIASPHLA FPSTTGLLAA QCLGAARGLE ATASPGLLKP KNGSGELSYG 
EVMGPLEKPG GRHKCRFCAK VFGSDSALQI HLRSHTGERP YKCNVCGNRF TTRGNLKVHF 
HRHREKYPHV QMNPHPVPEH LDYVITSSGL PYGMSVPPEK AEEEAATPGG GVERKPLVAS 
TTALSATESL TLLSTSAGTA TAPGLPAFNK FVLMKAVEPK NKADENTPPG SEGSAISGVA 
ESSTATRMQL SKLVTSLPSW ALLTNHFKST GSFPFPYVLE PLGASPSETS KLQQLVEKID 
RQGAVAVTSA ASGAPTTSAP APSSSASSGP NQCVICLRVL SCPRALRLHY GQHGGERPFK 
CKVCGRAFST RGNLRAHFVG HKASPAARAQ NSCPICQKKF TNAVTLQQHV RMHLGGQIPN 
GGTALPEGGG AAQENGSEQS TVSGARSFPQ QQSQQPSPEE ELSEEEEEED EEEEEDVTDE 
DSLAGRGSES GGEKAISVRG DSEEASGAEE EVGTVAAAAT AGKEMDSNEK TTQQSSLPPP 
PPPDSLDQPQ PMEQGSSGVL GGKEEGGKPE RSSSPASALT PEGEATSVTL VEELSLQEAM 
RKEPGESSSR KACEVCGQAF PSQAALEEHQ KTHPKEGPLF TCVFCRQGFL ERATLKKHML 
LAHHQVQPFA PHGPQNIAAL SLVPGCSPSI TSTGLSPFPR KDDPTIP

Genular Protein ID: 3509079137

Symbol: B4DK65_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DK65

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 3 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SAM 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 906
  • Mass: 95422
  • Checksum: 8A871514DE78E253
  • Sequence:
    • MAHESERSSR LGVPCGEPAE LGGDASEEDH PQVCAKCCAQ FTDPTEFLAH QNACSTDPPV 
MVIIGGQENP NNSSASSEPR PEGHNNPQVM DTEHSNPPDS GSSVPTDPTW GPERRGEESP 
GHFLVAATGA ETPKQAFFHL YHPLGSQHPF SAGGVGRSHK PTPAPSPALP GSTDQLIASP 
HLAFPSTTGL LAAQCLGAAR GLEATASPGL LKPKNGSGEL SYGEVMGPLE KPGGRHKCRF 
CAKVFGSDSA LQIHLRSHTG ERPYKCNVCG NRFTTRGNLK VHFHRHREKY PHVQMNPHPV 
PEHLDYVITS SGLPYGMSVP PEKAEEEAAT PGGGVERKPL VASTTALSAT ESLTLLSTSA 
GTATAPGLPA FNKFVLMKAV EPKNKADENT PPGSEGSAIS GVAESSTATR MQLSKLVTSL 
PSWALLTNHF KSTGSFPFPY VLEPLGASPS ETSKLQQLVE KIDRQGAVAV TSAASGAPTT 
SAPAPSSSAS SGPNQCVICL RVLSCPRALR LHYGQHGGER PFKCKVCGRA FSTRGNLRAH 
FVGHKASPAA RAQNSCPICQ KKFTNAVTLQ QHVRMHLGGQ IPNGGTALPE GGGAAQENGS 
EQSTVSGARS FPQQQSQQPS PEEELSEEEE EEDEEEEEDV TDEDSLAGRG SESGGEKAIS 
VRGDSEEASG AEEEVGTVAA AATAGKEMDS NEKTTQQSSL PPPPPPDSLD QPQPMEQGSS 
GVLGGKEEGG KPERSSSPAS ALTPEGEATS VTLVEELSLQ EAMRKEPGES SSRKACEVCG 
QAFPSQAALE EHQKTHPKEG PLFTCVFCRQ GFLERATLKK HMLLAHHQNQ YVAFLSNGLP 
MKPWNSSSTS TTTPSLAPPV LFGLGTVAGK VPPTMGSREA KEKTAPLLFQ PPAPKAVPEK 
PIIDKK

Genular Protein ID: 309855411

Symbol: E7EW59_HUMAN

Name: N/A

UniProtKB Accession Codes:

E7EW59

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 2 ExpressionAtlas 1 GO 2 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12508121

Title: The DNA sequence and analysis of human chromosome 14.

PubMed ID: 12508121

DOI: 10.1038/nature01348

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

Sequence Information:

  • Length: 906
  • Mass: 95412
  • Checksum: CB0E57FEEF1DA3E3
  • Sequence:
    • MAHESERSSR LGVPCGEPAE LGGDASEEDH PQVCAKCCAQ FTDPTEFLAH QNACSTDPPV 
MVIIGGQENP NNSSASSEPR PEGHNNPQVM DTEHSNPPDS GSSVPTDPTW GPERRGEESS 
GHFLVAATGA ETPKQAFFHL YHPLGSQHPF SAGGVGRSHK PTPAPSPALP GSTDQLIASP 
HLAFPSTTGL LAAQCLGAAR GLEATASPGL LKPKNGSGEL SYGEVMGPLE KPGGRHKCRF 
CAKVFGSDSA LQIHLRSHTG ERPYKCNVCG NRFTTRGNLK VHFHRHREKY PHVQMNPHPV 
PEHLDYVITS SGLPYGMSVP PEKAEEEAAT PGGGVERKPL VASTTALSAT ESLTLLSTSA 
GTATAPGLPA FNKFVLMKAV EPKNKADENT PPGSEGSAIS GVAESSTATR MQLSKLVTSL 
PSWALLTNHF KSTGSFPFPY VLEPLGASPS ETSKLQQLVE KIDRQGAVAV TSAASGAPTT 
SAPAPSSSAS SGPNQCVICL RVLSCPRALR LHYGQHGGER PFKCKVCGRA FSTRGNLRAH 
FVGHKASPAA RAQNSCPICQ KKFTNAVTLQ QHVRMHLGGQ IPNGGTALPE GGGAAQENGS 
EQSTVSGARS FPQQQSQQPS PEEELSEEEE EEDEEEEEDV TDEDSLAGRG SESGGEKAIS 
VRGDSEEASG AEEEVGTVAA AATAGKEMDS NEKTTQQSSL PPPPPPDSLD QPQPMEQGSS 
GVLGGKEEGG KPERSSSPAS ALTPEGEATS VTLVEELSLQ EAMRKEPGES SSRKACEVCG 
QAFPSQAALE EHQKTHPKEG PLFTCVFCRQ GFLERATLKK HMLLAHHQNQ YVAFLSNGLP 
MKPWNSSSTS TTTPSLAPPV LFGLGTVAGK VPPTMGSREA KEKTAPLLFQ PPAPKAVPEK 
PIIDKK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.