Details for: HIF3A

Gene ID: 64344

Symbol: HIF3A

Ensembl ID: ENSG00000124440

Description: hypoxia inducible factor 3 subunit alpha

Associated with

Other Information

Genular Protein ID: 2974439232

Symbol: HIF3A_HUMAN

Name: Basic-helix-loop-helix-PAS protein MOP7

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11573933

Title: Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha.

PubMed ID: 11573933

DOI: 10.1006/bbrc.2001.5659

PubMed ID: 16126907

Title: Human HIF-3alpha4 is a dominant-negative regulator of HIF-1 and is down-regulated in renal cell carcinoma.

PubMed ID: 16126907

DOI: 10.1096/fj.05-3788com

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12538644

Title: Multiple splice variants of the human HIF-3 alpha locus are targets of the von Hippel-Lindau E3 ubiquitin ligase complex.

PubMed ID: 12538644

DOI: 10.1074/jbc.m208681200

PubMed ID: 16775626

Title: Hypoxia upregulates hypoxia inducible factor (HIF)-3alpha expression in lung epithelial cells: characterization and comparison with HIF-1alpha.

PubMed ID: 16775626

DOI: 10.1038/sj.cr.7310072

PubMed ID: 17998805

Title: Dominant-negative HIF-3 alpha 4 suppresses VHL-null renal cell carcinoma progression.

PubMed ID: 17998805

DOI: 10.4161/cc.6.22.4947

PubMed ID: 19694616

Title: The human HIF (hypoxia-inducible factor)-3alpha gene is a HIF-1 target gene and may modulate hypoxic gene induction.

PubMed ID: 19694616

DOI: 10.1042/bj20090120

PubMed ID: 20416395

Title: Hypoxia-inducible factor (HIF)-3alpha is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2.

PubMed ID: 20416395

DOI: 10.1016/j.biocel.2010.04.008

PubMed ID: 21069422

Title: Cell-specific and hypoxia-dependent regulation of human HIF-3alpha: inhibition of the expression of HIF target genes in vascular cells.

PubMed ID: 21069422

DOI: 10.1007/s00018-010-0575-4

Sequence Information:

  • Length: 669
  • Mass: 72433
  • Checksum: 81C4C84517000DE2
  • Sequence:
  • MALGLQRARS TTELRKEKSR DAARSRRSQE TEVLYQLAHT LPFARGVSAH LDKASIMRLT 
    ISYLRMHRLC AAGEWNQVGA GGEPLDACYL KALEGFVMVL TAEGDMAYLS ENVSKHLGLS 
    QLELIGHSIF DFIHPCDQEE LQDALTPQQT LSRRKVEAPT ERCFSLRMKS TLTSRGRTLN 
    LKAATWKVLN CSGHMRAYKP PAQTSPAGSP DSEPPLQCLV LICEAIPHPG SLEPPLGRGA 
    FLSRHSLDMK FTYCDDRIAE VAGYSPDDLI GCSAYEYIHA LDSDAVSKSI HTLLSKGQAV 
    TGQYRFLARS GGYLWTQTQA TVVSGGRGPQ SESIVCVHFL ISQVEETGVV LSLEQTEQHS 
    RRPIQRGAPS QKDTPNPGDS LDTPGPRILA FLHPPSLSEA ALAADPRRFC SPDLRRLLGP 
    ILDGASVAAT PSTPLATRHP QSPLSADLPD ELPVGTENVH RLFTSGKDTE AVETDLDIAQ 
    DADALDLEML APYISMDDDF QLNASEQLPR AYHRPLGAVP RPRARSFHGL SPPALEPSLL 
    PRWGSDPRLS CSSPSRGDPS ASSPMAGARK RTLAQSSEDE DEGVELLGVR PPKRSPSPEH 
    ENFLLFPLSL SFLLTGGPAP GSLQDPSTPL LNLNEPLGLG PSLLSPYSDE DTTQPGGPFQ 
    PRAGSAQAD

Genular Protein ID: 2221852890

Symbol: H0YDZ5_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 450
  • Mass: 48574
  • Checksum: 75E1791B14449283
  • Sequence:
  • MRPAAGAARR PRCCTSWLTR CPSPAASAPT WTRPLSCASP SATCACTASA PQLELIGHSI 
    FDFIHPCDQE ELQDALTPQQ TLSRRKVEAP TERCFSLRMK STLTSRGRTL NLKAATWKVL 
    NCSGHMRAYK PPAQTSPAGS PDSEPPLQCL VLICEAIPHP GSLEPPLGRG AFLSRHSLDM 
    KFTYCDDRIA EVAGYSPDDL IGCSAYEYIH ALDSDAVSKS IHTLLSKGQA VTGQYRFLAR 
    SGGYLWTQTQ ATVVSGGRGP QSESIVCVHF LISQVEETGV VLSLEQTEQH SRRPIQRGAP 
    SQKDTPNPGD SLDTPGPRIL AFLHPPSLSE AALAADPRRF CSPDLRRLLG PILDGASVAA 
    TPSTPLATRH PQSPLSADLP DELPVGTENV HRLFTSGKDT EAVETDLDIA QDPSTPLLNL 
    NEPLGFHFVT QSGVQWHKHS SPQPRPPGLK

Genular Protein ID: 1963473332

Symbol: B2RBI6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 667
  • Mass: 72328
  • Checksum: 4C6E76238238DF85
  • Sequence:
  • MDWQDHRSTT ELRKEKSRDA ARSRRSQETE VLYQLAHTLP LARGVSAHLD KASIMRLTIS 
    YLRMHRLCAA GEWNQVGAGG EPLDACYLKA LEGFVMVLTA EGDMAYLSEN VSKHLGLSQL 
    ELIGHSIFDF IHPCDQEELQ DALTPQQTLS RRKVEAPTER CFSLRMKSTL TSRGRTLNLK 
    AATWKVLNCS GHMRAYKPPA QTSPAGSPDS EPPLQCLVLI CEAIPHPGSL EPPLGRGAFL 
    SRHSLDMKFT YCDDRIAEVA GYSPDDLIGC SAYEYIHALD SDAVSKSIHT LLSKGQAVTG 
    QYRFLARSGG YLWTQTQATV VSGGRGPQSE SIVCVHFLIS QVEETGVVLS LEQTEQHSRR 
    PIQRGAPSQK DTPNPGDSLD TPGPRILAFL HPPSLSEAAL AADPRRFCGP DLRRLLGPIL 
    DGASVAATPS TPLATRHPQS PLSADLPDEL PVGTENVHRL FTSGKDTEAV ETDLDTAQDA 
    DALDLEMLAP YISMDDDFQL NASEQLPRAY HRPLGAVPRP RARSFHGLSP PALEPSLLPR 
    WGSDPRLSCS SPSRGDPSAS SPMAGARKRT LAQSSEDEDE GVELLGVRPP KRSPSPEHEN 
    FLLFPLSLSF LLTGGPAPGS LQDPSTPLLN LNEPLGLGPS LLSPYSDEDT TQPGGPFQPR 
    AGSAQAD

Genular Protein ID: 3477765206

Symbol: M0R104_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

Sequence Information:

  • Length: 594
  • Mass: 64082
  • Checksum: 00A4DAE1AFCB39B8
  • Sequence:
  • MRPAAGAARR PRCCTSWLTR CPSPAASAPT WTRPLSCASP SATCACTASA PQLELIGHSI 
    FDFIHPCDQE ELQDALTPQQ TLSRRKVEAP TERCFSLRMK STLTSRGRTL NLKAATWKVL 
    NCSGHMRAYK PPAQTSPAGS PDSEPPLQCL VLICEAIPHP GSLEPPLGRG AFLSRHSLDM 
    KFTYCDDRIA EVAGYSPDDL IGCSAYEYIH ALDSDAVSKS IHTLLSKGQA VTGQYRFLAR 
    SGGYLWTQTQ ATVVSGGRGP QSESIVCVHF LISQVEETGV VLSLEQTEQH SRRPIQRGAP 
    SQKDTPNPGD SLDTPGPRIL AFLHPPSLSE AALAADPRRF CSPDLRRLLG PILDGASVAA 
    TPSTPLATRH PQSPLSADLP DELPVGTENV HRLFTSGKDT EAVETDLDIA QDADALDLEM 
    LAPYISMDDD FQLNASEQLP RAYHRPLGAV PRPRARSFHG LSPPALEPSL LPRWGSDPRL 
    SCSSPSRGDP SASSPMAGAR KRTLAQSSED EDEGVELLGV RPPKRSPSPE HENFLLFPLS 
    LSFLLTGGPA PGSLQDPSTP LLNLNEPLGF HFVTQSGVQW HKHSSPQPRP PGLK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.