Details for: SHB

Gene ID: 6461

Symbol: SHB

Ensembl ID: ENSG00000107338

Description: SH2 domain containing adaptor protein B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 124.3368
    Cell Significance Index: -19.3400
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 76.8007
    Cell Significance Index: -19.4800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 37.6732
    Cell Significance Index: -15.3100
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 16.0933
    Cell Significance Index: -15.3700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.7345
    Cell Significance Index: -19.4000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.9480
    Cell Significance Index: -19.5300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.9784
    Cell Significance Index: 230.5600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 1.7449
    Cell Significance Index: 30.8400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.6822
    Cell Significance Index: 166.4100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.4929
    Cell Significance Index: 111.2700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.3597
    Cell Significance Index: 37.0100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1637
    Cell Significance Index: 60.4500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0332
    Cell Significance Index: 62.0300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8926
    Cell Significance Index: 145.1700
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.7276
    Cell Significance Index: 7.3400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.7153
    Cell Significance Index: 17.8800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.6670
    Cell Significance Index: 4.1100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6032
    Cell Significance Index: 27.3400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.6027
    Cell Significance Index: 17.3700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5971
    Cell Significance Index: 41.3000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.5040
    Cell Significance Index: 10.9200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4967
    Cell Significance Index: 18.8100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4416
    Cell Significance Index: 12.6600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4278
    Cell Significance Index: 32.8300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3427
    Cell Significance Index: 15.9800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2814
    Cell Significance Index: 153.6800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2806
    Cell Significance Index: 12.4100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.2276
    Cell Significance Index: 16.1000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2208
    Cell Significance Index: 37.7100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2128
    Cell Significance Index: 42.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2109
    Cell Significance Index: 7.4100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2045
    Cell Significance Index: 25.1400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.1789
    Cell Significance Index: 3.8100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1762
    Cell Significance Index: 77.9000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1556
    Cell Significance Index: 28.0600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1441
    Cell Significance Index: 18.6200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1227
    Cell Significance Index: 5.7700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.1089
    Cell Significance Index: 5.6800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0962
    Cell Significance Index: 5.4000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0889
    Cell Significance Index: 31.8700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0854
    Cell Significance Index: 5.2500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0571
    Cell Significance Index: 10.8600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0079
    Cell Significance Index: 2.2600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0060
    Cell Significance Index: -4.5200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0064
    Cell Significance Index: -0.1700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0101
    Cell Significance Index: -19.0800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0121
    Cell Significance Index: -0.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0132
    Cell Significance Index: -24.3400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0134
    Cell Significance Index: -9.8900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0146
    Cell Significance Index: -10.6900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0151
    Cell Significance Index: -23.2600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0154
    Cell Significance Index: -20.8800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0267
    Cell Significance Index: -16.9800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0274
    Cell Significance Index: -15.4500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0416
    Cell Significance Index: -25.9500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0431
    Cell Significance Index: -19.5700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0480
    Cell Significance Index: -0.2900
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: -0.0529
    Cell Significance Index: -0.3800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0539
    Cell Significance Index: -6.1800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0568
    Cell Significance Index: -5.8000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0647
    Cell Significance Index: -8.2900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0857
    Cell Significance Index: -11.7700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0908
    Cell Significance Index: -18.0200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1043
    Cell Significance Index: -21.9600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1106
    Cell Significance Index: -1.8600
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1109
    Cell Significance Index: -2.3000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1251
    Cell Significance Index: -18.1900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1386
    Cell Significance Index: -1.9900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1555
    Cell Significance Index: -4.9800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1567
    Cell Significance Index: -4.2000
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1624
    Cell Significance Index: -19.1500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.1712
    Cell Significance Index: -3.6600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.1752
    Cell Significance Index: -2.5100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1893
    Cell Significance Index: -19.7100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1963
    Cell Significance Index: -15.5500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.2280
    Cell Significance Index: -2.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2297
    Cell Significance Index: -7.5200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2408
    Cell Significance Index: -7.6700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2458
    Cell Significance Index: -15.0700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2526
    Cell Significance Index: -15.9200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2711
    Cell Significance Index: -17.4900
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2742
    Cell Significance Index: -2.5300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.3029
    Cell Significance Index: -2.4700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3618
    Cell Significance Index: -18.2800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3740
    Cell Significance Index: -13.7300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3765
    Cell Significance Index: -19.7700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3774
    Cell Significance Index: -13.1200
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4141
    Cell Significance Index: -14.5100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4233
    Cell Significance Index: -10.5600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4372
    Cell Significance Index: -11.7000
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.4621
    Cell Significance Index: -7.9900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4675
    Cell Significance Index: -13.7700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4782
    Cell Significance Index: -10.1500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4791
    Cell Significance Index: -7.2200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.4872
    Cell Significance Index: -7.3000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.5108
    Cell Significance Index: -12.2500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.5257
    Cell Significance Index: -13.1300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.5304
    Cell Significance Index: -8.7400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5336
    Cell Significance Index: -11.1700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5342
    Cell Significance Index: -11.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** SHB is a 65-kDa protein that contains a SH2 domain, which is a highly conserved domain that binds to phosphotyrosine residues. This domain is essential for SHB's ability to interact with various signaling molecules and regulate downstream pathways. SHB is a member of the SH2-containing tyrosine phosphatase (SHPTP) family, which also includes SHP-1 and SHP-2. SHB is primarily expressed in the cytoplasm and is involved in the regulation of signaling pathways that control cell growth, survival, and migration. **Pathways and Functions:** SHB is involved in multiple signaling pathways that regulate cellular processes, including: 1. **Angiogenesis:** SHB is a key regulator of angiogenesis, a process essential for tumor growth and metastasis. SHB interacts with VEGFR2, a receptor tyrosine kinase that regulates angiogenesis, and modulates the activity of this receptor. 2. **T-cell receptor signaling pathway:** SHB is involved in the regulation of T-cell receptor signaling, which is essential for immune responses. SHB interacts with signaling molecules such as CD28 and CD40, and modulates the activity of these receptors. 3. **Vegfa-Vegfr2 pathway:** SHB is a key regulator of the Vegfa-Vegfr2 pathway, which is essential for angiogenesis and tumor growth. SHB interacts with Vegfr2 and modulates the activity of this receptor. 4. **Hematopoietic stem cell proliferation:** SHB is involved in the regulation of hematopoietic stem cell proliferation, which is essential for the development of blood cells. 5. **Cancer development:** SHB is overexpressed in various types of cancer, including breast, lung, and colon cancer. SHB promotes cancer development by regulating angiogenesis, immune evasion, and tumor growth. **Clinical Significance:** SHB has significant clinical implications, including: 1. **Cancer therapy:** SHB is a potential target for cancer therapy, as its overexpression is associated with poor prognosis and increased tumor growth. 2. **Angiogenesis:** SHB is a key regulator of angiogenesis, and its inhibition may provide a new therapeutic strategy for cancer treatment. 3. **Immunotherapy:** SHB is involved in the regulation of T-cell receptor signaling, and its inhibition may provide a new therapeutic strategy for immune-related disorders. 4. **Hematological disorders:** SHB is involved in the regulation of hematopoietic stem cell proliferation, and its dysregulation may contribute to hematological disorders such as leukemia and lymphoma. In conclusion, SHB is a multifaceted regulator of cellular processes that plays a significant role in angiogenesis, immune responses, and cancer development. Its dysregulation has significant clinical implications, including cancer therapy, angiogenesis inhibition, and immunotherapy. Further research is needed to fully understand the role of SHB in human disease and to develop effective therapeutic strategies targeting this protein.

Genular Protein ID: 966089715

Symbol: SHB_HUMAN

Name: SH2 domain-containing adapter protein B

UniProtKB Accession Codes:

Q15464 B9EGM0 D3DRQ5 Q504U5 Q5VUM8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 1 GO 15 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8302579

Title: Shb is a ubiquitously expressed Src homology 2 protein.

PubMed ID: 8302579

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7537362

Title: Molecular interactions of the Src homology 2 domain protein Shb with phosphotyrosine residues, tyrosine kinase receptors and Src homology 3 domain proteins.

PubMed ID: 7537362

PubMed ID: 8806685

Title: Apoptosis of NIH3T3 cells overexpressing the Src homology 2 domain protein Shb.

PubMed ID: 8806685

PubMed ID: 9751119

Title: The Src homology 2 domain protein Shb transmits basic fibroblast growth factor- and nerve growth factor-dependent differentiation signals in PC12 cells.

PubMed ID: 9751119

PubMed ID: 9484780

Title: Stimulation through the T cell receptor leads to interactions between SHB and several signaling proteins.

PubMed ID: 9484780

DOI: 10.1038/sj.onc.1201607

PubMed ID: 10488157

Title: Requirement of the Src homology 2 domain protein Shb for T cell receptor-dependent activation of the interleukin-2 gene nuclear factor for activation of T cells element in Jurkat T cells.

PubMed ID: 10488157

DOI: 10.1074/jbc.274.39.28050

PubMed ID: 10828022

Title: Endostatin-induced tyrosine kinase signaling through the Shb adaptor protein regulates endothelial cell apoptosis.

PubMed ID: 10828022

PubMed ID: 10837138

Title: Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization.

PubMed ID: 10837138

DOI: 10.1006/excr.2000.4896

PubMed ID: 10964504

Title: NGF-dependent neurite outgrowth in PC12 cells overexpressing the Src homology 2-domain protein shb requires activation of the Rap1 pathway.

PubMed ID: 10964504

DOI: 10.1006/excr.2000.4984

PubMed ID: 12200137

Title: IL-2 receptor signaling through the Shb adapter protein in T and NK cells.

PubMed ID: 12200137

DOI: 10.1016/s0006-291x(02)02016-8

PubMed ID: 12084069

Title: Shb links SLP-76 and Vav with the CD3 complex in Jurkat T cells.

PubMed ID: 12084069

DOI: 10.1046/j.1432-1033.2002.03008.x

PubMed ID: 12181353

Title: The Shb adaptor protein binds to tyrosine 766 in the FGFR-1 and regulates the Ras/MEK/MAPK pathway via FRS2 phosphorylation in endothelial cells.

PubMed ID: 12181353

DOI: 10.1091/mbc.e02-02-0103

PubMed ID: 12520086

Title: Overexpression of the Shb SH2 domain-protein in insulin-producing cells leads to altered signaling through the IRS-1 and IRS-2 proteins.

PubMed ID: 12520086

DOI: 10.1007/bf03402033

PubMed ID: 12464388

Title: The Shb adaptor protein causes Src-dependent cell spreading and activation of focal adhesion kinase in murine brain endothelial cells.

PubMed ID: 12464388

DOI: 10.1016/s0898-6568(02)00076-1

PubMed ID: 15026417

Title: The adaptor protein shb binds to tyrosine 1175 in vascular endothelial growth factor (VEGF) receptor-2 and regulates VEGF-dependent cellular migration.

PubMed ID: 15026417

DOI: 10.1074/jbc.m312729200

PubMed ID: 15919073

Title: Shb promotes blood vessel formation in embryoid bodies by augmenting vascular endothelial growth factor receptor-2 and platelet-derived growth factor receptor-beta signaling.

PubMed ID: 15919073

DOI: 10.1016/j.yexcr.2005.04.020

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

Sequence Information:

  • Length: 509
  • Mass: 55042
  • Checksum: 15C392A6EEB761D6
  • Sequence:
    • MAKWLNKYFS LGNSKTKSPP QPPRPDYREQ RRRGERPSQP PQAVPQASSA ASASCGPATA 
SCFSASSGSL PDDSGSTSDL IRAYRAQKER DFEDPYNGPG SSLRKLRAMC RLDYCGGSGE 
PGGVQRAFSA SSASGAAGCC CASSGAGAAA SSSSSSGSPH LYRSSSERRP ATPAEVRYIS 
PKHRLIKVES AAGGGAGDPL GGACAGGRTW SPTACGGKKL LNKCAASAAE ESGAGKKDKV 
TIADDYSDPF DAKNDLKSKA GKGESAGYME PYEAQRIMTE FQRQESVRSQ HKGIQLYDTP 
YEPEGQSVDS DSESTVSPRL RESKLPQDDD RPADEYDQPW EWNRVTIPAL AAQFNGNEKR 
QSSPSPSRDR RRQLRAPGGG FKPIKHGSPE FCGILGERVD PAVPLEKQIW YHGAISRGDA 
ENLLRLCKEC SYLVRNSQTS KHDYSLSLRS NQGFMHMKLA KTKEKYVLGQ NSPPFDSVPE 
VIHYYTTRKL PIKGAEHLSL LYPVAVRTL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.