Details for: SNAPC3
Gene ID: 6619
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SNAPC3
Ensembl ID: ENSG00000164975
Description: small nuclear RNA activating complex polypeptide 3
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 6.84rCSI 11.71%PRS 71.29
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CSI 6.3rCSI 22.69%PRS 42.51
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CSI 6.14rCSI 16.28%PRS 73.61
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CSI 5.74rCSI 3.99%PRS 73.73
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CSI 4.95rCSI 3.69%PRS 78.86
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CSI 4.95rCSI 7.56%PRS 66.65
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CSI 4.42rCSI 17.83%PRS 61.11
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CSI 4.21rCSI 8.96%PRS 61.59
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CSI 3.75rCSI 9.77%PRS 62.18
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CSI 3.74rCSI 6.56%PRS 54.23
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CSI 3.65rCSI 2.81%PRS 62.96
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CSI 3.16rCSI 2.77%PRS 68.02
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CSI 3.15rCSI 2.84%PRS 59.35
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CSI 2.96rCSI 4.35%PRS 55.82
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CSI 2.96rCSI 5.12%PRS 52.53
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CSI 2.95rCSI 9.51%PRS 60.42
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CSI 2.85rCSI 2.8%PRS 65.11
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CSI 2.79rCSI 2.31%PRS 64.66
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CSI 2.75rCSI 3.18%PRS 52.59
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CSI 2.67rCSI 2.78%PRS 62.71
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CSI 2.66rCSI 1.97%PRS 54.94
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CSI 2.57rCSI 3.2%PRS 42.2
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CSI 2.55rCSI 2.11%PRS 61.83
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CSI 2.52rCSI 2.21%PRS 71.97
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CSI 2.48rCSI 3.69%PRS 63.8
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CSI 2.47rCSI 4.95%PRS 51.47
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CSI 2.41rCSI 5.5%PRS 54.14
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CSI 2.41rCSI 2.53%PRS 66.11
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CSI 2.38rCSI 1.88%PRS 49.25
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CSI 2.35rCSI 6.6%PRS 59.01
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CSI 2.33rCSI 2.99%PRS 67.32
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CSI 2.33rCSI 3.91%PRS 44.11
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CSI 2.33rCSI 5.22%PRS 44.83
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CSI 2.3rCSI 3.27%PRS 58.72
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CSI 2.27rCSI 2.82%PRS 64.1
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CSI 2.24rCSI 2.88%PRS 54.77
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CSI 2.23rCSI 5.43%PRS 42.73
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CSI 2.2rCSI 6.87%PRS 45.76
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CSI 2.17rCSI 8.15%PRS 54.35
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CSI 2.15rCSI 12.69%PRS 45.34
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CSI 2.14rCSI 3.77%PRS 43.2
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CSI 2.12rCSI 1.43%PRS 75.73
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CSI 2.12rCSI 2.7%PRS 68.91
-
CSI 2.08rCSI 3.31%PRS 54.78
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CSI 2.07rCSI 4.73%PRS 62.33
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CSI 2.06rCSI 49.37%PRS 43.13
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CSI 2.05rCSI 4.26%PRS 59.54
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CSI 2.05rCSI 2.5%PRS 70
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CSI 2.04rCSI 1.79%PRS 50.33
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CSI 2.04rCSI 3.65%PRS 61.43
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CSI 2.02rCSI 2.96%PRS 67.26
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CSI 2.02rCSI 4.15%PRS 52.62
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CSI 2.01rCSI 2.41%PRS 60.54
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CSI 2rCSI 48.35%PRS 43.97
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CSI 1.95rCSI 2.09%PRS 62.03
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CSI 1.95rCSI 4.49%PRS 51.47
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CSI 1.94rCSI 3.15%PRS 59.04
-
CSI 1.92rCSI 2.01%PRS 60.44
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CSI 1.9rCSI 9.08%PRS 62.32
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CSI 1.89rCSI 3.02%PRS 54.92
-
CSI 1.88rCSI 2.52%PRS 71.39
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CSI 1.88rCSI 1.97%PRS 58.87
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CSI 1.87rCSI 1.8%PRS 53.12
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CSI 1.86rCSI 3.28%PRS 70.56
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CSI 1.83rCSI 1.58%PRS 67.47
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CSI 1.8rCSI 3.65%PRS 41.71
-
CSI 1.79rCSI 3.35%PRS 50.69
-
CSI 1.78rCSI 2.2%PRS 59.09
-
CSI 1.77rCSI 5.22%PRS 65.55
-
CSI 1.75rCSI 2.56%PRS 58.45
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CSI 1.74rCSI 2.69%PRS 60.68
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CSI 1.72rCSI 2.39%PRS 60.97
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CSI 1.69rCSI 3.07%PRS 54.18
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CSI 1.67rCSI 3%PRS 55.55
-
CSI 1.65rCSI 1.91%PRS 55.5
-
CSI 1.65rCSI 2.44%PRS 67.73
-
CSI 1.61rCSI 2.06%PRS 59.63
-
CSI 1.6rCSI 1.6%PRS 55.78
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CSI 1.58rCSI 6.44%PRS 74.49
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CSI 1.57rCSI 4.15%PRS 71.22
-
CSI 1.56rCSI 2.75%PRS 59.26
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CSI 1.56rCSI 1.86%PRS 43.85
-
CSI 1.55rCSI 1.2%PRS 64.43
-
CSI 1.53rCSI 1.57%PRS 76.55
-
CSI 1.53rCSI 1.77%PRS 70.01
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CSI 1.52rCSI 3.84%PRS 51.91
-
CSI 1.41rCSI 5.32%PRS 44.84
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CSI 1.4rCSI 1.8%PRS 45.42
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CSI 1.39rCSI 1.89%PRS 64.13
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CSI 1.38rCSI 1.98%PRS 51.95
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CSI 1.36rCSI 3.51%PRS 57.37
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CSI 1.33rCSI 2.9%PRS 75.82
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CSI 1.32rCSI 10.71%PRS 55.64
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CSI 1.29rCSI 1.69%PRS 76.01
-
CSI 1.29rCSI 8.03%PRS 54.13
-
CSI 1.26rCSI 3.12%PRS 60.88
-
CSI 1.26rCSI 1.72%PRS 54.25
-
CSI 1.24rCSI 2.47%PRS 60.14
-
CSI 1.24rCSI 2.72%PRS 70.39
-
CSI 1.23rCSI 3.48%PRS 60.37
-
CSI 0.2rCSI 2.0%PRS 49.6%
-
CSI 0.4rCSI 2.6%PRS 49.0%
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CSI 0.5rCSI 1.3%PRS 56.6%
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CSI 0.6rCSI 1.9%PRS 48.3%
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CSI 0.7rCSI 2.4%PRS 47.5%
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CSI 0.8rCSI 15.6%PRS 54.5%
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CSI 0.8rCSI 2.1%PRS 53.4%
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CSI 0.8rCSI 1.2%PRS 58.7%
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CSI 0.8rCSI 2.6%PRS 67.4%
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CSI 0.8rCSI 1.9%PRS 49.6%
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CSI 0.8rCSI 1.8%PRS 48.6%
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CSI 0.8rCSI 2.8%PRS 51.1%
-
CSI 0.9rCSI 1.4%PRS 52.0%
-
CSI 0.9rCSI 2.5%PRS 73.7%
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CSI 0.9rCSI 3.6%PRS 76.7%
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CSI 0.9rCSI 13.3%PRS 53.4%
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CSI 1.0rCSI 2.6%PRS 69.4%
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CSI 1.0rCSI 5.6%PRS 47.5%
-
CSI 1.0rCSI 2.6%PRS 59.8%
-
CSI 1.0rCSI 2.3%PRS 60.4%
-
CSI 1.0rCSI 4.0%PRS 53.2%
-
CSI 1.1rCSI 1.8%PRS 51.7%
-
CSI 1.1rCSI 21.9%PRS 53.2%
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CSI 1.1rCSI 2.5%PRS 66.4%
-
CSI 1.1rCSI 3.2%PRS 52.1%
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CSI 1.2rCSI 1.7%PRS 78.3%
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CSI 1.2rCSI 3.7%PRS 59.5%
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CSI 1.2rCSI 5.1%PRS 62.0%
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CSI 1.2rCSI 1.9%PRS 46.1%
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CSI 1.2rCSI 3.5%PRS 60.4%
-
CSI 1.2rCSI 2.7%PRS 70.4%
-
CSI 1.2rCSI 2.5%PRS 60.1%
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CSI 1.3rCSI 1.7%PRS 54.3%
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CSI 1.3rCSI 3.1%PRS 60.9%
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CSI 1.3rCSI 8.0%PRS 54.1%
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CSI 1.3rCSI 1.7%PRS 76.0%
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CSI 1.3rCSI 10.7%PRS 55.6%
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CSI 1.3rCSI 2.9%PRS 75.8%
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CSI 1.4rCSI 3.5%PRS 57.4%
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CSI 1.4rCSI 2.0%PRS 52.0%
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CSI 1.4rCSI 1.9%PRS 64.1%
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CSI 1.4rCSI 1.8%PRS 45.4%
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CSI 1.4rCSI 5.3%PRS 44.8%
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CSI 1.5rCSI 3.8%PRS 51.9%
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CSI 1.5rCSI 1.8%PRS 70.0%
-
CSI 1.5rCSI 1.6%PRS 76.6%
-
CSI 1.6rCSI 1.2%PRS 64.4%
-
CSI 1.6rCSI 1.9%PRS 43.9%
-
CSI 1.6rCSI 2.8%PRS 59.3%
-
CSI 1.6rCSI 4.2%PRS 71.2%
-
CSI 1.6rCSI 6.4%PRS 74.5%
-
CSI 1.6rCSI 1.6%PRS 55.8%
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CSI 1.6rCSI 2.1%PRS 59.6%
-
CSI 1.7rCSI 2.4%PRS 67.7%
-
CSI 1.7rCSI 1.9%PRS 55.5%
-
CSI 1.7rCSI 3.0%PRS 55.6%
-
CSI 1.7rCSI 3.1%PRS 54.2%
-
CSI 1.7rCSI 2.4%PRS 61.0%
-
CSI 1.7rCSI 2.7%PRS 60.7%
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CSI 1.8rCSI 2.6%PRS 58.5%
-
CSI 1.8rCSI 5.2%PRS 65.6%
-
CSI 1.8rCSI 2.2%PRS 59.1%
-
CSI 1.8rCSI 3.4%PRS 50.7%
-
CSI 1.8rCSI 3.7%PRS 41.7%
-
CSI 1.8rCSI 1.6%PRS 67.5%
-
CSI 1.9rCSI 3.3%PRS 70.6%
-
CSI 1.9rCSI 1.8%PRS 53.1%
-
CSI 1.9rCSI 2.0%PRS 58.9%
-
CSI 1.9rCSI 2.5%PRS 71.4%
-
CSI 1.9rCSI 3.0%PRS 54.9%
-
CSI 1.9rCSI 9.1%PRS 62.3%
-
CSI 1.9rCSI 2.0%PRS 60.4%
-
CSI 1.9rCSI 3.2%PRS 59.0%
-
CSI 2.0rCSI 4.5%PRS 51.5%
-
CSI 2.0rCSI 2.1%PRS 62.0%
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CSI 2.0rCSI 48.4%PRS 44.0%
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CSI 2.0rCSI 2.4%PRS 60.5%
-
CSI 2.0rCSI 4.2%PRS 52.6%
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CSI 2.0rCSI 3.0%PRS 67.3%
-
CSI 2.0rCSI 3.7%PRS 61.4%
-
CSI 2.0rCSI 1.8%PRS 50.3%
-
CSI 2.1rCSI 2.5%PRS 70.0%
-
CSI 2.1rCSI 4.3%PRS 59.5%
-
CSI 2.1rCSI 49.4%PRS 43.1%
-
CSI 2.1rCSI 4.7%PRS 62.3%
-
CSI 2.1rCSI 3.3%PRS 54.8%
-
CSI 2.1rCSI 2.7%PRS 68.9%
-
CSI 2.1rCSI 1.4%PRS 75.7%
-
CSI 2.1rCSI 3.8%PRS 43.2%
-
CSI 2.2rCSI 12.7%PRS 45.3%
-
CSI 2.2rCSI 8.2%PRS 54.4%
-
CSI 2.2rCSI 6.9%PRS 45.8%
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CSI 2.2rCSI 5.4%PRS 42.7%
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CSI 2.2rCSI 2.9%PRS 54.8%
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CSI 2.3rCSI 2.8%PRS 64.1%
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CSI 2.3rCSI 3.3%PRS 58.7%
-
CSI 2.3rCSI 5.2%PRS 44.8%
-
CSI 2.3rCSI 3.9%PRS 44.1%
-
CSI 2.3rCSI 3.0%PRS 67.3%
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CSI 2.4rCSI 6.6%PRS 59.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 1191183903
Symbol: SNPC3_HUMAN
Name: snRNA-activating protein complex subunit 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9003788
Title: Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc.
PubMed ID: 9003788
PubMed ID: 8816454
Title: Cloning and characterization of the beta subunit of human proximal sequence element-binding transcription factor and its involvement in transcription of small nuclear RNA genes by RNA polymerases II and III.
PubMed ID: 8816454
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11056176
Title: A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.
PubMed ID: 11056176
PubMed ID: 12621023
Title: The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.
PubMed ID: 12621023
PubMed ID: 17525332
Title: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.
PubMed ID: 17525332
Sequence Information:
- Length: 411
- Mass: 46753
- Checksum: 920584BE4CFA366A
- Sequence:
MAEGSRGGPT CSGVGGRQDP VSGSGGCNFP EYELPELNTR AFHVGAFGEL WRGRLRGAGD LSLREPPASA LPGSQAADSD REDAAVARDL DCSLEAAAEL RAVCGLDKLK CLEDGEDPEV IPENTDLVTL GVRKRFLEHR EETITIDRAC RQETFVYEME SHAIGKKPEN SADMIEEGEL ILSVNILYPV IFHKHKEHKP YQTMLVLGSQ KLTQLRDSIR CVSDLQIGGE FSNTPDQAPE HISKDLYKSA FFYFEGTFYN DKRYPECRDL SRTIIEWSES HDRGYGKFQT ARMEDFTFND LCIKLGFPYL YCHQGDCEHV IVITDIRLVH HDDCLDRTLY PLLIKKHWLW TRKCFVCKMY TARWVTNNDS FAPEDPCFFC DVCFRMLHYD SEGNKLGEFL AYPYVDPGTF N