Details for: SPOCK1
Gene ID: 6695
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: SPOCK1
Ensembl ID: ENSG00000152377
Description: SPARC (osteonectin), cwcv and kazal like domains proteoglycan 1
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 39.07rCSI 57.43%PRS 71.42
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CSI 37.74rCSI 48.66%PRS 61.41
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CSI 36.75rCSI 45.72%PRS 58.2
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CSI 34.33rCSI 57.62%PRS 60.33
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CSI 32.42rCSI 52.14%PRS 61.98
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CSI 29.28rCSI 51.71%PRS 59.58
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CSI 25.31rCSI 30.24%PRS 60.33
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CSI 22.84rCSI 54.63%PRS 65.53
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CSI 22.05rCSI 53.58%PRS 58.34
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CSI 21.22rCSI 38.55%PRS 69.9
-
CSI 20.76rCSI 41.69%PRS 68.45
-
CSI 19.48rCSI 46.82%PRS 81.97
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CSI 18.88rCSI 59.05%PRS 64.38
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CSI 17.9rCSI 39.38%PRS 61.11
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CSI 17.43rCSI 37.81%PRS 66.31
-
CSI 16.1rCSI 37.16%PRS 66.44
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CSI 16.03rCSI 36.59%PRS 69.95
-
CSI 16rCSI 52.6%PRS 64.96
-
CSI 15.89rCSI 54.42%PRS 65.06
-
CSI 15.65rCSI 41.66%PRS 66.39
-
CSI 15.62rCSI 24%PRS 68.37
-
CSI 15.07rCSI 56.97%PRS 60.8
-
CSI 15.01rCSI 42.68%PRS 74.64
-
CSI 14.85rCSI 38.68%PRS 73.53
-
CSI 13.94rCSI 52.6%PRS 61.25
-
CSI 13.58rCSI 23.48%PRS 69.81
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CSI 13.39rCSI 17.19%PRS 68.82
-
CSI 13.38rCSI 10.87%PRS 77.7
-
CSI 13.31rCSI 38.57%PRS 67.91
-
CSI 13.03rCSI 46.88%PRS 58.27
-
CSI 12.87rCSI 18.46%PRS 68.24
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CSI 12.44rCSI 11.58%PRS 79
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CSI 12.39rCSI 23.21%PRS 66.74
-
CSI 12.06rCSI 35.65%PRS 69.54
-
CSI 11.88rCSI 24.12%PRS 56.81
-
CSI 11.23rCSI 23.07%PRS 66.2
-
CSI 11.18rCSI 49.7%PRS 78.98
-
CSI 11.09rCSI 16.9%PRS 75.34
-
CSI 11.01rCSI 12.74%PRS 70.55
-
CSI 10.94rCSI 15.51%PRS 75.17
-
CSI 10.51rCSI 42.81%PRS 70.8
-
CSI 10.41rCSI 14.42%PRS 75.78
-
CSI 10.17rCSI 24.83%PRS 70.99
-
CSI 9.93rCSI 10.65%PRS 79.59
-
CSI 9.69rCSI 15.87%PRS 67.91
-
CSI 9.69rCSI 8.35%PRS 79.52
-
CSI 9.53rCSI 12.23%PRS 74.55
-
CSI 9.45rCSI 16.57%PRS 71.91
-
CSI 9.03rCSI 12.31%PRS 69.95
-
CSI 8.51rCSI 50.13%PRS 61.09
-
CSI 7.87rCSI 17.64%PRS 61.16
-
CSI 7.78rCSI 26.07%PRS 62.57
-
CSI 7.47rCSI 24.29%PRS 76.31
-
CSI 7.3rCSI 11.15%PRS 78.72
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CSI 7.29rCSI 11.51%PRS 80.04
-
CSI 7.26rCSI 53.33%PRS 65.79
-
CSI 6.87rCSI 38.32%PRS 81.95
-
CSI 6.66rCSI 17.8%PRS 70.05
-
CSI 6.56rCSI 15.67%PRS 82.66
-
CSI 6.55rCSI 55.16%PRS 66.54
-
CSI 6.29rCSI 26.74%PRS 70.91
-
CSI 6.16rCSI 29.48%PRS 74.97
-
CSI 5.92rCSI 22.53%PRS 69.27
-
CSI 5.91rCSI 15.37%PRS 85.79
-
CSI 5.81rCSI 27.82%PRS 78.36
-
CSI 5.59rCSI 17.99%PRS 75.47
-
CSI 5.51rCSI 33.91%PRS 84.67
-
CSI 5.5rCSI 31.99%PRS 82.38
-
CSI 5.49rCSI 31.03%PRS 64.4
-
CSI 5.33rCSI 13.7%PRS 75.58
-
CSI 4.93rCSI 22.01%PRS 62.95
-
CSI 4.85rCSI 9.63%PRS 74.33
-
CSI 4.78rCSI 13.18%PRS 73.57
-
CSI 4.49rCSI 4.41%PRS 81.2
-
CSI 4.23rCSI 9.33%PRS 64.24
-
CSI 3.76rCSI 12.03%PRS 75.62
-
CSI 3.74rCSI 5%PRS 77.32
-
CSI 3.69rCSI 5.06%PRS 70.4
-
CSI 3.48rCSI 13.86%PRS 86.19
-
CSI 3.45rCSI 15.16%PRS 67.07
-
CSI 3.23rCSI 10.1%PRS 61.96
-
CSI 3.17rCSI 8.92%PRS 73.5
-
CSI 3.13rCSI 8.09%PRS 73.75
-
CSI 3.12rCSI 19.52%PRS 59.13
-
CSI 3.09rCSI 27.19%PRS 66.93
-
CSI 2.9rCSI 8.29%PRS 85.51
-
CSI 2.81rCSI 24.25%PRS 66.43
-
CSI 2.67rCSI 3.23%PRS 59.74
-
CSI 2.48rCSI 10.43%PRS 84.04
-
CSI 2.31rCSI 55.35%PRS 58.76
-
CSI 2.29rCSI 55.17%PRS 59.29
-
CSI 2.28rCSI 9.04%PRS 74.61
-
CSI 2.26rCSI 12.13%PRS 86.41
-
CSI 1.96rCSI 2.05%PRS 81.8
-
CSI 1.94rCSI 7.5%PRS 87.47
-
CSI 1.82rCSI 16.83%PRS 80.48
-
CSI 1.8rCSI 19.02%PRS 75.06
-
CSI 1.39rCSI 20.61%PRS 85.31
-
CSI 1.3rCSI 2.88%PRS 77.73
-
CSI 1.3rCSI 9.48%PRS 86.82
-
CSI 0.4rCSI 2.0%PRS 73.5%
-
CSI 1.2rCSI 7.8%PRS 70.1%
-
CSI 1.3rCSI 9.5%PRS 86.8%
-
CSI 1.3rCSI 2.9%PRS 77.7%
-
CSI 1.4rCSI 20.6%PRS 85.3%
-
CSI 1.8rCSI 19.0%PRS 75.1%
-
CSI 1.8rCSI 16.8%PRS 80.5%
-
CSI 1.9rCSI 7.5%PRS 87.5%
-
CSI 2.0rCSI 2.1%PRS 81.8%
-
CSI 2.3rCSI 12.1%PRS 86.4%
-
CSI 2.3rCSI 9.0%PRS 74.6%
-
CSI 2.3rCSI 55.2%PRS 59.3%
-
CSI 2.3rCSI 55.4%PRS 58.8%
-
CSI 2.5rCSI 10.4%PRS 84.0%
-
CSI 2.7rCSI 3.2%PRS 59.7%
-
CSI 2.8rCSI 24.3%PRS 66.4%
-
CSI 2.9rCSI 8.3%PRS 85.5%
-
CSI 3.1rCSI 27.2%PRS 66.9%
-
CSI 3.1rCSI 19.5%PRS 59.1%
-
CSI 3.1rCSI 8.1%PRS 73.8%
-
CSI 3.2rCSI 8.9%PRS 73.5%
-
CSI 3.2rCSI 10.1%PRS 62.0%
-
CSI 3.5rCSI 15.2%PRS 67.1%
-
CSI 3.5rCSI 13.9%PRS 86.2%
-
CSI 3.7rCSI 5.1%PRS 70.4%
-
CSI 3.7rCSI 5.0%PRS 77.3%
-
CSI 3.8rCSI 12.0%PRS 75.6%
-
CSI 4.2rCSI 9.3%PRS 64.2%
-
CSI 4.5rCSI 4.4%PRS 81.2%
-
CSI 4.8rCSI 13.2%PRS 73.6%
-
CSI 4.9rCSI 9.6%PRS 74.3%
-
CSI 4.9rCSI 22.0%PRS 63.0%
-
CSI 5.3rCSI 13.7%PRS 75.6%
-
CSI 5.5rCSI 31.0%PRS 64.4%
-
CSI 5.5rCSI 32.0%PRS 82.4%
-
CSI 5.5rCSI 33.9%PRS 84.7%
-
CSI 5.6rCSI 18.0%PRS 75.5%
-
CSI 5.8rCSI 27.8%PRS 78.4%
-
CSI 5.9rCSI 15.4%PRS 85.8%
-
CSI 5.9rCSI 22.5%PRS 69.3%
-
CSI 6.2rCSI 29.5%PRS 75.0%
-
CSI 6.3rCSI 26.7%PRS 70.9%
-
CSI 6.6rCSI 55.2%PRS 66.5%
-
CSI 6.6rCSI 15.7%PRS 82.7%
-
CSI 6.7rCSI 17.8%PRS 70.1%
-
CSI 6.9rCSI 38.3%PRS 82.0%
-
CSI 7.3rCSI 53.3%PRS 65.8%
-
CSI 7.3rCSI 11.5%PRS 80.0%
-
CSI 7.3rCSI 11.2%PRS 78.7%
-
CSI 7.5rCSI 24.3%PRS 76.3%
-
CSI 7.8rCSI 26.1%PRS 62.6%
-
CSI 7.9rCSI 17.6%PRS 61.2%
-
CSI 8.5rCSI 50.1%PRS 61.1%
-
CSI 9.0rCSI 12.3%PRS 70.0%
-
CSI 9.5rCSI 16.6%PRS 71.9%
-
CSI 9.5rCSI 12.2%PRS 74.6%
-
CSI 9.7rCSI 8.4%PRS 79.5%
-
CSI 9.7rCSI 15.9%PRS 67.9%
-
CSI 9.9rCSI 10.7%PRS 79.6%
-
CSI 10.2rCSI 24.8%PRS 71.0%
-
CSI 10.4rCSI 14.4%PRS 75.8%
-
CSI 10.5rCSI 42.8%PRS 70.8%
-
CSI 10.9rCSI 15.5%PRS 75.2%
-
CSI 11.0rCSI 12.7%PRS 70.6%
-
CSI 11.1rCSI 16.9%PRS 75.3%
-
CSI 11.2rCSI 49.7%PRS 79.0%
-
CSI 11.2rCSI 23.1%PRS 66.2%
-
CSI 11.9rCSI 24.1%PRS 56.8%
-
CSI 12.1rCSI 35.7%PRS 69.5%
-
CSI 12.4rCSI 23.2%PRS 66.7%
-
CSI 12.4rCSI 11.6%PRS 79.0%
-
CSI 12.9rCSI 18.5%PRS 68.2%
-
CSI 13.0rCSI 46.9%PRS 58.3%
-
CSI 13.3rCSI 38.6%PRS 67.9%
-
CSI 13.4rCSI 10.9%PRS 77.7%
-
CSI 13.4rCSI 17.2%PRS 68.8%
-
CSI 13.6rCSI 23.5%PRS 69.8%
-
CSI 13.9rCSI 52.6%PRS 61.3%
-
CSI 14.9rCSI 38.7%PRS 73.5%
-
CSI 15.0rCSI 42.7%PRS 74.6%
-
CSI 15.1rCSI 57.0%PRS 60.8%
-
CSI 15.6rCSI 24.0%PRS 68.4%
-
CSI 15.7rCSI 41.7%PRS 66.4%
-
CSI 15.9rCSI 54.4%PRS 65.1%
-
CSI 16.0rCSI 52.6%PRS 65.0%
-
CSI 16.0rCSI 36.6%PRS 70.0%
-
CSI 16.1rCSI 37.2%PRS 66.4%
-
CSI 17.4rCSI 37.8%PRS 66.3%
-
CSI 17.9rCSI 39.4%PRS 61.1%
-
CSI 18.9rCSI 59.1%PRS 64.4%
-
CSI 19.5rCSI 46.8%PRS 82.0%
-
CSI 20.8rCSI 41.7%PRS 68.5%
-
CSI 21.2rCSI 38.6%PRS 69.9%
-
CSI 22.1rCSI 53.6%PRS 58.3%
-
CSI 22.8rCSI 54.6%PRS 65.5%
-
CSI 25.3rCSI 30.2%PRS 60.3%
-
CSI 29.3rCSI 51.7%PRS 59.6%
-
CSI 32.4rCSI 52.1%PRS 62.0%
-
CSI 34.3rCSI 57.6%PRS 60.3%
-
CSI 36.8rCSI 45.7%PRS 58.2%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 2103839081
Symbol: TICN1_HUMAN
Name: Testican-1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8389704
Title: Testican, a multidomain testicular proteoglycan resembling modulators of cell social behaviour.
PubMed ID: 8389704
PubMed ID: 9272383
Title: Endothelial cell expression of testican mRNA.
PubMed ID: 9272383
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15372022
Title: The DNA sequence and comparative analysis of human chromosome 5.
PubMed ID: 15372022
DOI: 10.1038/nature02919
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1463459
Title: Characterization of a human seminal plasma glycosaminoglycan-bearing polypeptide.
PubMed ID: 1463459
DOI: 10.1042/bj2880565
PubMed ID: 23234360
Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.
PubMed ID: 23234360
DOI: 10.1021/pr300963h
Sequence Information:
- Length: 439
- Mass: 49124
- Checksum: 1971601D90F1D0AD
- Sequence:
MPAIAVLAAA AAAWCFLQVE SRHLDALAGG AGPNHGNFLD NDQWLSTVSQ YDRDKYWNRF RDDDYFRNWN PNKPFDQALD PSKDPCLKVK CSPHKVCVTQ DYQTALCVSR KHLLPRQKKG NVAQKHWVGP SNLVKCKPCP VAQSAMVCGS DGHSYTSKCK LEFHACSTGK SLATLCDGPC PCLPEPEPPK HKAERSACTD KELRNLASRL KDWFGALHED ANRVIKPTSS NTAQGRFDTS ILPICKDSLG WMFNKLDMNY DLLLDPSEIN AIYLDKYEPC IKPLFNSCDS FKDGKLSNNE WCYCFQKPGG LPCQNEMNRI QKLSKGKSLL GAFIPRCNEE GYYKATQCHG STGQCWCVDK YGNELAGSRK QGAVSCEEEQ ETSGDFGSGG SVVLLDDLEY ERELGPKDKE GKLRVHTRAV TEDDEDEDDD KEDEVGYIW