Details for: TAF2

Gene ID: 6873

Symbol: TAF2

Ensembl ID: ENSG00000064313

Description: TATA-box binding protein associated factor 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 217.9430
    Cell Significance Index: -33.9000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 138.5410
    Cell Significance Index: -35.1400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 79.5026
    Cell Significance Index: -37.5400
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 75.0510
    Cell Significance Index: -30.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 29.4252
    Cell Significance Index: -36.2800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.1063
    Cell Significance Index: -35.1100
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.8325
    Cell Significance Index: -30.2000
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.3334
    Cell Significance Index: -36.8300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 8.8413
    Cell Significance Index: -19.3500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7445
    Cell Significance Index: 349.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.6454
    Cell Significance Index: 326.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5618
    Cell Significance Index: 154.5000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.5099
    Cell Significance Index: 84.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1777
    Cell Significance Index: 1063.3900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.0327
    Cell Significance Index: 20.1600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9032
    Cell Significance Index: 323.9800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9031
    Cell Significance Index: 624.6100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.8759
    Cell Significance Index: 11.9500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8437
    Cell Significance Index: 137.2200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8274
    Cell Significance Index: 90.0000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.8069
    Cell Significance Index: 20.1700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.8022
    Cell Significance Index: 20.6200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.8005
    Cell Significance Index: 22.3700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.7475
    Cell Significance Index: 87.1100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.7161
    Cell Significance Index: 54.9600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6948
    Cell Significance Index: 41.7100
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6563
    Cell Significance Index: 17.5900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.6257
    Cell Significance Index: 13.3800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.5388
    Cell Significance Index: 15.5300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5289
    Cell Significance Index: 32.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4829
    Cell Significance Index: 21.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4827
    Cell Significance Index: 18.2800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.4658
    Cell Significance Index: 31.3200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3937
    Cell Significance Index: 70.9700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.3674
    Cell Significance Index: 45.1800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.3495
    Cell Significance Index: 24.1700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3208
    Cell Significance Index: 6.9500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2648
    Cell Significance Index: 36.3600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2326
    Cell Significance Index: 127.0500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1579
    Cell Significance Index: 69.7900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1528
    Cell Significance Index: 1.9000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1447
    Cell Significance Index: 3.4700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1295
    Cell Significance Index: 2.2200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1031
    Cell Significance Index: 19.6200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0951
    Cell Significance Index: 11.2200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0895
    Cell Significance Index: 168.5300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0821
    Cell Significance Index: 52.1700
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0808
    Cell Significance Index: 1.7700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0786
    Cell Significance Index: 2.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0779
    Cell Significance Index: 35.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0706
    Cell Significance Index: 3.6700
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0561
    Cell Significance Index: 1.6000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0476
    Cell Significance Index: 73.3100
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0413
    Cell Significance Index: 76.1100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0359
    Cell Significance Index: 1.2600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0281
    Cell Significance Index: 38.1800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0268
    Cell Significance Index: 1.2500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0057
    Cell Significance Index: -0.9800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0081
    Cell Significance Index: -1.0400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0128
    Cell Significance Index: -8.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0165
    Cell Significance Index: -12.1900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0263
    Cell Significance Index: -3.8200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0329
    Cell Significance Index: -24.1200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0366
    Cell Significance Index: -20.6400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0428
    Cell Significance Index: -32.4200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0989
    Cell Significance Index: -4.6500
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0991
    Cell Significance Index: -2.1100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1044
    Cell Significance Index: -21.9900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1057
    Cell Significance Index: -6.6600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1075
    Cell Significance Index: -30.9400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1176
    Cell Significance Index: -8.3200
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.1276
    Cell Significance Index: -1.8400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1342
    Cell Significance Index: -13.7100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1482
    Cell Significance Index: -19.1500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1757
    Cell Significance Index: -9.1500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1946
    Cell Significance Index: -8.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1951
    Cell Significance Index: -12.5900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2003
    Cell Significance Index: -22.9500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.2108
    Cell Significance Index: -5.7400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2211
    Cell Significance Index: -3.7000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2350
    Cell Significance Index: -26.8300
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.2493
    Cell Significance Index: -3.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2510
    Cell Significance Index: -18.7100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2705
    Cell Significance Index: -28.1700
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.3269
    Cell Significance Index: -1.9800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3759
    Cell Significance Index: -6.3300
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4140
    Cell Significance Index: -32.7900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4491
    Cell Significance Index: -23.5800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.4938
    Cell Significance Index: -7.2900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5156
    Cell Significance Index: -31.6100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5298
    Cell Significance Index: -13.9300
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.5313
    Cell Significance Index: -15.2300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.5436
    Cell Significance Index: -6.4800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.5516
    Cell Significance Index: -18.0600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.5605
    Cell Significance Index: -17.8500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5805
    Cell Significance Index: -12.3200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.5808
    Cell Significance Index: -11.4900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.5834
    Cell Significance Index: -4.7600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.5918
    Cell Significance Index: -17.3800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.6035
    Cell Significance Index: -20.9700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Subunit of TFIID complex**: TAF2 is a component of the TFIID complex, which is responsible for recruiting RNA polymerase II to specific promoters and initiating transcription. 2. **Chromatin binding**: TAF2 exhibits chromatin-binding properties, allowing it to regulate gene expression by modulating chromatin structure and accessibility. 3. **Transcriptional regulation**: TAF2 plays a crucial role in regulating transcription by interacting with various transcription factors, including TP53, and influencing the transcriptional landscape of target genes. 4. **Neuronal specificity**: TAF2 is predominantly expressed in neuronal cells, where it influences the development and function of various neural populations. **Pathways and Functions:** 1. **Chromatin binding and gene expression**: TAF2 regulates chromatin structure and accessibility, influencing the expression of target genes through its association with chromatin-binding proteins. 2. **Transcription initiation**: TAF2 collaborates with TBP to initiate transcription at specific promoters, facilitating the recruitment of RNA polymerase II. 3. **Immune response**: TAF2 modulates the response to viral infections, such as HIV, by regulating the expression of immune-related genes and influencing the activity of immune cells. 4. **TP53 regulation**: TAF2 interacts with TP53 to regulate its activity, influencing the transcriptional response to DNA damage and other cellular stresses. 5. **RNA polymerase II regulation**: TAF2 regulates the activity of RNA polymerase II, influencing the transcriptional output of various promoters. **Clinical Significance:** 1. **Immune-related diseases**: TAF2 dysregulation has been implicated in various immune-related diseases, including HIV-associated immunodeficiency and autoimmune disorders. 2. **Neurological disorders**: TAF2 expression is altered in neurological disorders, such as Alzheimer's disease and Parkinson's disease, highlighting its potential role in neurodegenerative diseases. 3. **Cancer**: TAF2 is overexpressed in certain types of cancer, suggesting its potential involvement in tumorigenesis and cancer progression. 4. **Viral infections**: TAF2 plays a critical role in regulating the response to viral infections, such as HIV, highlighting its potential as a therapeutic target for antiviral therapies. In conclusion, TAF2 is a multifunctional transcription factor that plays a critical role in regulating gene expression, particularly in the context of immune responses. Its dysregulation has been implicated in various immune-related diseases and neurological disorders, highlighting its potential as a therapeutic target for the treatment of these conditions. Further research is needed to fully elucidate the molecular mechanisms of TAF2 and its role in human disease.

Genular Protein ID: 416182364

Symbol: TAF2_HUMAN

Name: Transcription initiation factor TFIID subunit 2

UniProtKB Accession Codes:

Q6P1X5 B2RE82 O43487 O43604 O60668 Q86WW7 Q8IWK4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 3 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 9 EMDB 11 Ensembl 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MEROPS 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 28 PDBsum 28 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 9 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9418870

Title: CIF150, a human cofactor for transcription factor IID-dependent initiator function.

PubMed ID: 9418870

DOI: 10.1128/mcb.18.1.233

PubMed ID: 9774672

Title: Novel cofactors and TFIIA mediate functional core promoter selectivity by the human TAFII150-containing TFIID complex.

PubMed ID: 9774672

DOI: 10.1128/mcb.18.11.6571

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12601814

Title: Novel subunits of the TATA binding protein free TAFII-containing transcription complex identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry following one-dimensional gel electrophoresis.

PubMed ID: 12601814

DOI: 10.1002/pmic.200390030

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 33795473

Title: Structural insights into preinitiation complex assembly on core promoters.

PubMed ID: 33795473

DOI: 10.1126/science.aba8490

PubMed ID: 21937992

Title: Deep sequencing reveals 50 novel genes for recessive cognitive disorders.

PubMed ID: 21937992

DOI: 10.1038/nature10423

PubMed ID: 24084144

Title: Microcephaly thin corpus callosum intellectual disability syndrome caused by mutated TAF2.

PubMed ID: 24084144

DOI: 10.1016/j.pediatrneurol.2013.07.017

Sequence Information:

  • Length: 1199
  • Mass: 136971
  • Checksum: 169DA4A3878CFD59
  • Sequence:
    • MPLTGVEPAR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE LTIFPTVANL 
NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ RNLNYFSNAY AAAVSAVDPD 
AGNGELCIKV PSELWKHVDE LKVLKIHINF SLDQPKGGLH FVVPSVEGSM AERGAHVFSC 
GYQNSTRFWF PCVDSYSELC TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI 
PTAASNISLA IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYLHEVFEF YEEILTCRYP 
YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQSL AQQFFGCFIS 
RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YRHWIKEELD KIVAYELKTG GVLLHPIFGG 
GKEKDNPASH LHFSIKHPHT LSWEYYSMFQ CKAHLVMRLI ENRISMEFML QVFNKLLSLA 
STASSQKFQS HMWSQMLVST SGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK 
RNVLELEIKQ DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK 
KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ YQLRYERDVV 
AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF CLAKIANSMV STWTGPPAMK 
SLFTRMFCCK SCPNIVKTNN FMSFQSYFLQ KTMPVAMALL RDVHNLCPKE VLTFILDLIK 
YNDNRKNKFS DNYYRAEMID ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME 
KLLPSYRHTI TVSCLRAIRV LQKNGHVPSD PALFKSYAEY GHFVDIRIAA LEAVVDYTKV 
DRSYEELQWL LNMIQNDPVP YVRHKILNML TKNPPFTKNM ESPLCNEALV DQLWKLMNSG 
TSHDWRLRCG AVDLYFTLFG LSRPSCLPLP ELGLVLNLKE KKAVLNPTII PESVAGNQEA 
ANNPSSHPQL VGFQNPFSSS QDEEEIDMDT VHDSQAFISH HLNMLERPST PGLSKYRPAS 
SRSALIPQHS AGCDSTPTTK PQWSLELARK GTGKEQAPLE MSMHPAASAP LSVFTKESTA 
SKHSDHHHHH HHEHKKKKKK HKHKHKHKHK HDSKEKDKEP FTFSSPASGR SIRSPSLSD

Genular Protein ID: 80589545

Symbol: A0A8I5KV60_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8I5KV60

Database IDs:

ARBA 7 CDD 1 CTD 1 DisGeNET 1 EMBL 2 Ensembl 2 GO 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1251
  • Mass: 142680
  • Checksum: 749C93170E8A0443
  • Sequence:
    • MPLTGVEPAR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE LTIFPTVANL 
NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ RNLNYFSNAY AAAVSAVDPD 
AGNGELCIKV PSELWKHVDE LKVLKIHINF SLDQPKGGLH FVVPSVEGSM AERGAHVFSC 
GYQNSTRFWF PCVDSYSELC TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI 
PTAASNISLA IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYLHEVFEF YEEILTCRYP 
YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQSL AQQFFGCFIS 
RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YRHWIKEELD KIVAYELKTG GVLLHPIFGG 
GKEKDNPASH LHFSIKHPHT LSWEYYSMFQ CKAHLVMRLI ENRISMEFML QVFNKLLSLA 
STASSQKFQS HMWSQMLVST SGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK 
RNVLELEIKQ DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK 
KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ YQLRYERDVV 
AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF CLAKIANSMV STWTGPPAMK 
SLFTRMFCCK SCPNIVKTNN FMSFQSYFLQ KTMPVAMALL RDVHNLCPKE VLTFILDLIK 
YNDNRKNKFS DNYYRAEMID ALANSVTPAV SVNNEVRTLD NLNPDVRLIL EEITRFLNME 
KLLPSYRHTI TVSCLRAIRV LQKNGHVPSD PALFKSYAEY GHFVDIRIAA LEAVVDYTKV 
DRSYEELQWL LNMIQNDPVP YVRHKILNML TKNPPFTKNM ESPLCNEALV DQLWKLMNSG 
TSHDWRLRCG AVDLYFTLFG LSRPSCLPLP ELGLVLNLKE KKAVLNPTII PESVAGNQEA 
ANNPSSHPQL VGFQNPEDDH LAKEASCNIS AHQQGVKRKS DTPLGSPLEP GQILEKNEDS 
SKVKLKIRFS SSQDEEEIDM DTVHDSQAFI SHHLNMLERP STPGLSKYRP ASSRSALIPQ 
HSAGCDSTPT TKPQWSLELA RKGTGKEQAP LEMSMHPAAS APLSVFTKES TASKHSDHHH 
HHHHEHKKKK KKHKHKHKHK HKHDSKEKDK EPFTFSSPAS GRSIRSPSLS D

Genular Protein ID: 210423589

Symbol: A0A8I5KSY6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8I5KSY6

Database IDs:

ARBA 7 CDD 1 CTD 1 DisGeNET 1 EMBL 2 Ensembl 2 GO 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1162
  • Mass: 132661
  • Checksum: 88F167E75DA85429
  • Sequence:
    • MPLTGVEPAR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE LTIFPTVANL 
NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ RNLNYFSNAY AAAVSAVDPD 
AGNGELCIKV PSELWKHVDE LKVLKIHINF SLDQPKGGLH FVVPSVEGSM AERGAHVFSC 
GYQNSTRFWF PCVDSYSELC TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI 
PTAASNISLA IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYLHEVFEF YEEILTCRYP 
YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQSL AQQFFGCFIS 
RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YRHWIKEELD KIVAYELKTG GVLLHPIFGG 
GKEKDNPASH LHFSIKHPHT LSWEYYSMFQ CKAHLVMRLI ENRISMEFML QVFNKLLSLA 
STASSQKFQS HMWSQMLVST SGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK 
RNVLELEIKQ DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK 
KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ YQLRYERDVV 
AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF CLAKIANSMV STWTGPPAMK 
SLFTRMFCCK SCPNIVKTNN FMSFQSYFLQ KFSDNYYRAE MIDALANSVT PAVSVNNEVR 
TLDNLNPDVR LILEEITRFL NMEKLLPSYR HTITVSCLRA IRVLQKNGHV PSDPALFKSY 
AEYGHFVDIR IAALEAVVDY TKVDRSYEEL QWLLNMIQND PVPYVRHKIL NMLTKNPPFT 
KNMESPLCNE ALVDQLWKLM NSGTSHDWRL RCGAVDLYFT LFGLSRPSCL PLPELGLVLN 
LKEKKAVLNP TIIPESVAGN QEAANNPSSH PQLVGFQNPF SSSQDEEEID MDTVHDSQAF 
ISHHLNMLER PSTPGLSKYR PASSRSALIP QHSAGCDSTP TTKPQWSLEL ARKGTGKEQA 
PLEMSMHPAA SAPLSVFTKE STASKHSDHH HHHHHEHKKK KKKHKHKHKH KHKHDSKEKD 
KEPFTFSSPA SGRSIRSPSL SD

Genular Protein ID: 1721854319

Symbol: A0A8I5QJR0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8I5QJR0

Database IDs:

ARBA 7 CDD 1 CTD 1 DisGeNET 1 EMBL 2 Ensembl 2 GO 1 Gene3D 2 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1214
  • Mass: 138370
  • Checksum: FAC80C9C3A5985CF
  • Sequence:
    • MPLTGVEPAR MNRKKGDKGF ESPRPYKLTH QVVCINNINF QRKSVVGFVE LTIFPTVANL 
NRIKLNSKQC RIYRVRINDL EAAFIYNDPT LEVCHSESKQ RNLNYFSNAY AAAVSAVDPD 
AGNGELCIKV PSELWKHVDE LKVLKIHINF SLDQPKGGLH FVVPSVEGSM AERGAHVFSC 
GYQNSTRFWF PCVDSYSELC TWKLEFTVDA AMVAVSNGDL VETVYTHDMR KKTFHYMLTI 
PTAASNISLA IGPFEILVDP YMHEVTHFCL PQLLPLLKHT TSYLHEVFEF YEEILTCRYP 
YSCFKTVFID EAYVEVAAYA SMSIFSTNLL HSAMIIDETP LTRRCLAQSL AQQFFGCFIS 
RMSWSDEWVL KGISGYIYGL WMKKTFGVNE YRHWIKEELD KIVAYELKTG GVLLHPIFGG 
GKEKDNPASH LHFSIKHPHT LSWEYYSMFQ CKAHLVMRLI ENRISMEFML QVFNKLLSLA 
STASSQKFQS HMWSQMLVST SGFLKSISNV SGKDIQPLIK QWVDQSGVVK FYGSFAFNRK 
RNVLELEIKQ DYTSPGTQKY VGPLKVTVQE LDGSFNHTLQ IEENSLKHDI PCHSKSRRNK 
KKKIPLMNGE EVDMDLSAMD ADSPLLWIRI DPDMSVLRKV EFEQADFMWQ YQLRYERDVV 
AQQESILALE KFPTPASRLA LTDILEQEQC FYRVRMSACF CLAKIANSMV STWTGPPAMK 
SLFTRMFCCK SCPNIVKTNN FMSFQSYFLQ KFSDNYYRAE MIDALANSVT PAVSVNNEVR 
TLDNLNPDVR LILEEITRFL NMEKLLPSYR HTITVSCLRA IRVLQKNGHV PSDPALFKSY 
AEYGHFVDIR IAALEAVVDY TKVDRSYEEL QWLLNMIQND PVPYVRHKIL NMLTKNPPFT 
KNMESPLCNE ALVDQLWKLM NSGTSHDWRL RCGAVDLYFT LFGLSRPSCL PLPELGLVLN 
LKEKKAVLNP TIIPESVAGN QEAANNPSSH PQLVGFQNPE DDHLAKEASC NISAHQQGVK 
RKSDTPLGSP LEPGQILEKN EDSSKVKLKI RFSSSQDEEE IDMDTVHDSQ AFISHHLNML 
ERPSTPGLSK YRPASSRSAL IPQHSAGCDS TPTTKPQWSL ELARKGTGKE QAPLEMSMHP 
AASAPLSVFT KESTASKHSD HHHHHHHEHK KKKKKHKHKH KHKHKHDSKE KDKEPFTFSS 
PASGRSIRSP SLSD

Genular Protein ID: 17954622

Symbol: B3KMD8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KMD8

Database IDs:

ARBA 1 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 PharmGKB 1 RefSeq 1 SAM 1 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 504
  • Mass: 57037
  • Checksum: 8F19AD6E0764BECC
  • Sequence:
    • MSACFCLAKI ANSMVSTWTG PPAMKSLFTR MFCCKSCPNI VKTNNFKSFQ SYFLQKTTPV 
AMALLRDVHN LCPKEVLTFI LDLIKYNDNR KNKFSDNYYR AEMIDALANS VTPAVSVNNE 
VRTLDNLNPD VRLILEEITR FLNMEKLLPS YRHTITVSCL RAIRVLQKNG HVPSDPALFK 
SYAEYGHFVD IRIAALEAVV DYTKVDRSYE ELQWLLNMIQ NDPVPYVRHK ILNMLTKNPP 
FTKNMESPLC NEALVDQLWK LMNSGTSHDW RLRCGAVDLY FTLFGLSRPS CLPLPELGLV 
LNLKEKKAVL NPTIIPESVA GNQEAANNPS SHPQLVGFQN PFSSSQDEEE IDMDTVHDSQ 
AFISHHLNML ERPSTPGLSK YRPASSRSAL IPQHSAGCDS TPTTKPQWSL ELARKGTGKE 
QAPLEMSMHP AASAPLSVFT KESTASKHSD HHHHHHHEHK KKKKKHKHKH KHKHKHDSKE 
KDKEPFTFSS PASGRSIRSP SLSD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.