Details for: CLIP2

Gene ID: 7461

Symbol: CLIP2

Ensembl ID: ENSG00000106665

Description: CAP-Gly domain containing linker protein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 223.0220
    Cell Significance Index: -34.6900
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 131.2473
    Cell Significance Index: -33.2900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 74.9402
    Cell Significance Index: -30.4500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 31.9772
    Cell Significance Index: -30.5300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.1356
    Cell Significance Index: -34.6900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 13.5617
    Cell Significance Index: -36.3300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 13.1941
    Cell Significance Index: -40.5300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.4993
    Cell Significance Index: -20.7900
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 8.8037
    Cell Significance Index: -34.7400
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 3.9016
    Cell Significance Index: 123.4000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.3864
    Cell Significance Index: 74.1500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.6540
    Cell Significance Index: 36.2100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0726
    Cell Significance Index: 415.7600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.7321
    Cell Significance Index: 201.8600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.6982
    Cell Significance Index: 609.1300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1778
    Cell Significance Index: 1063.5000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.1205
    Cell Significance Index: 28.0100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0697
    Cell Significance Index: 212.2900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.0406
    Cell Significance Index: 29.0800
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.9928
    Cell Significance Index: 61.0200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.9861
    Cell Significance Index: 23.6500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.8842
    Cell Significance Index: 25.4800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.8281
    Cell Significance Index: 17.9400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8280
    Cell Significance Index: 572.7000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.8088
    Cell Significance Index: 23.0800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.7934
    Cell Significance Index: 35.9600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6837
    Cell Significance Index: 111.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5819
    Cell Significance Index: 25.7400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.5711
    Cell Significance Index: 38.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4557
    Cell Significance Index: 25.5700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4312
    Cell Significance Index: 16.3300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3774
    Cell Significance Index: 24.3500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3308
    Cell Significance Index: 32.7200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3226
    Cell Significance Index: 61.3900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2658
    Cell Significance Index: 18.3800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2440
    Cell Significance Index: 8.5800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.2137
    Cell Significance Index: 290.5600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1896
    Cell Significance Index: 23.3100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1190
    Cell Significance Index: 2.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0752
    Cell Significance Index: 13.5500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0667
    Cell Significance Index: 102.6200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0578
    Cell Significance Index: 36.7200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0521
    Cell Significance Index: 98.0800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0316
    Cell Significance Index: 58.3700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0060
    Cell Significance Index: 3.2800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0045
    Cell Significance Index: -0.7600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0059
    Cell Significance Index: -2.6000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0208
    Cell Significance Index: -2.8500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0228
    Cell Significance Index: -10.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0269
    Cell Significance Index: -3.9100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0393
    Cell Significance Index: -28.8100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0472
    Cell Significance Index: -35.0000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0494
    Cell Significance Index: -37.3600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0613
    Cell Significance Index: -38.3100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0644
    Cell Significance Index: -36.3000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.0662
    Cell Significance Index: -0.6100
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.0795
    Cell Significance Index: -1.0600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1048
    Cell Significance Index: -12.3700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.1123
    Cell Significance Index: -1.1700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1225
    Cell Significance Index: -35.2400
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.1418
    Cell Significance Index: -1.4300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1423
    Cell Significance Index: -3.0300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1483
    Cell Significance Index: -16.9900
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1544
    Cell Significance Index: -8.0400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1767
    Cell Significance Index: -3.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1890
    Cell Significance Index: -39.8100
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2004
    Cell Significance Index: -15.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.2237
    Cell Significance Index: -28.6800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2357
    Cell Significance Index: -30.4500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2535
    Cell Significance Index: -25.8900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2967
    Cell Significance Index: -30.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3581
    Cell Significance Index: -22.5700
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3589
    Cell Significance Index: -3.9100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3953
    Cell Significance Index: -12.5900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4100
    Cell Significance Index: -32.4700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4322
    Cell Significance Index: -14.1500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.4463
    Cell Significance Index: -33.2600
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.4496
    Cell Significance Index: -6.4000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.4567
    Cell Significance Index: -32.3000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4653
    Cell Significance Index: -9.2000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4659
    Cell Significance Index: -24.4600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.4668
    Cell Significance Index: -28.6200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.4985
    Cell Significance Index: -10.5800
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5005
    Cell Significance Index: -26.0000
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.5035
    Cell Significance Index: -7.2100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.5100
    Cell Significance Index: -6.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.5243
    Cell Significance Index: -24.6400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5873
    Cell Significance Index: -11.7900
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.5983
    Cell Significance Index: -7.5500
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.6513
    Cell Significance Index: -8.2200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.6623
    Cell Significance Index: -14.3100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6656
    Cell Significance Index: -17.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.6737
    Cell Significance Index: -23.6000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.6815
    Cell Significance Index: -17.0000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.7085
    Cell Significance Index: -33.0400
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.7284
    Cell Significance Index: -7.8100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.7847
    Cell Significance Index: -20.9900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.8037
    Cell Significance Index: -23.0400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.8159
    Cell Significance Index: -13.6600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.8176
    Cell Significance Index: -21.5000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** CLIP2 is a small protein encoded by the CLIP2 gene, with a conserved CAP-Gly domain that enables its interaction with microtubules. This domain is essential for its role in regulating cytoskeletal dynamics, particularly at the plus-end of microtubules. The protein's ability to bind microtubules and other cytoskeletal components positions it as a key regulator of cellular morphology and movement. **Pathways and Functions:** CLIP2 is involved in several key cellular pathways, including: 1. **Cell Cortex:** CLIP2 plays a crucial role in maintaining the structural integrity of the cell cortex, which is essential for cell shape, movement, and division. 2. **Cytoplasmic Microtubule Organization:** CLIP2 regulates the dynamics of microtubules, ensuring proper organization and function of the cytoskeleton. 3. **Microtubule Associated Complex:** CLIP2 interacts with other microtubule-associated proteins to form complexes that regulate microtubule function and stability. 4. **Microtubule Binding:** CLIP2's CAP-Gly domain enables its binding to microtubules, which is essential for its role in regulating cytoskeletal dynamics. In addition to its role in regulating cytoskeletal dynamics, CLIP2 has been implicated in various cellular processes, including: * Cell migration and adhesion * Cell division and mitosis * Axonal growth and guidance * Cytoskeletal remodeling **Clinical Significance:** Dysregulation of CLIP2 has been implicated in various disease states, including: 1. **Neurodegenerative Disorders:** CLIP2 has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's, where dysregulation of the cytoskeleton and microtubules can lead to neuronal dysfunction and death. 2. **Cancer:** CLIP2's role in regulating cell migration and adhesion has made it a potential target for cancer therapy. 3. **Neurodevelopmental Disorders:** CLIP2 has been implicated in neurodevelopmental disorders such as autism and schizophrenia, where dysregulation of the cytoskeleton and microtubules can contribute to cognitive and behavioral deficits. In conclusion, CLIP2 is a multifunctional gene that plays a crucial role in maintaining cellular organization and function. Its dysregulation has been implicated in various disease states, highlighting the need for further research into the mechanisms underlying its function and its potential therapeutic applications. As an expert immunologist, I hope this review has provided a comprehensive understanding of the enigmatic role of CLIP2 in cellular biology and its potential implications for human health.

Genular Protein ID: 2952260555

Symbol: CLIP2_HUMAN

Name: CAP-Gly domain-containing linker protein 2

UniProtKB Accession Codes:

Q9UDT6 O14527 O43611

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 CarbonylDB 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9179496

Title: Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.

PubMed ID: 9179496

DOI: 10.1093/dnares/4.1.53

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 8812460

Title: Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients.

PubMed ID: 8812460

DOI: 10.1006/geno.1996.0469

PubMed ID: 9799601

Title: The murine CYLN2 gene: genomic organization, chromosome localization, and comparison to the human gene that is located within the 7q11.23 Williams syndrome critical region.

PubMed ID: 9799601

DOI: 10.1006/geno.1998.5529

PubMed ID: 11290329

Title: Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

PubMed ID: 11290329

DOI: 10.1016/s0092-8674(01)00288-4

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22608712

Title: The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

PubMed ID: 22608712

DOI: 10.1016/j.ajhg.2012.04.020

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1046
  • Mass: 115837
  • Checksum: 7A0B3C796E1C6E25
  • Sequence:
    • MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG PSSSPAAAAA 
PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN 
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDAHS VESLTAQNLS LHSGTATPPL 
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE 
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK 
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA 
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL 
VESVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE TQTQLEHARI GELEQSLLLE 
KAQAERLLRE LADNRLTTVA EKSRVLQLEE ELTLRRGEIE ELQQCLLHSG PPPPDHPDAA 
EILRLRERLL SASKEHQRES GVLRDKYEKA LKAYQAEVDK LRAANEKYAQ EVAGLKDKVQ 
QATSENMGLM DNWKSKLDSL ASDHQKSLED LKATLNSGPG AQQKEIGELK AVMEGIKMEH 
QLELGNLQAK HDLETAMHVK EKEALREKLQ EAQEELAGLQ RHWRAQLEVQ ASQHRLELQE 
AQDQRRDAEL RVHELEKLDV EYRGQAQAIE FLKEQISLAE KKMLDYERLQ RAEAQGKQEV 
ESLREKLLVA ENRLQAVEAL CSSQHTHMIE SNDISEETIR TKETVEGLQD KLNKRDKEVT 
ALTSQTEMLR AQVSALESKC KSGEKKVDAL LKEKRRLEAE LETVSRKTHD ASGQLVLISQ 
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI RGLREKLTGL 
DKEKSLSDQR RYSLIDRSSA PELLRLQHQL MSTEDALRDA LDQAQQVEKL MEAMRSCPDK 
AQTIGNSGSA NGIHQQDKAQ KQEDKH

Genular Protein ID: 490495042

Symbol: A0A140VJG6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A140VJG6

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 5 Gene3D 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 1046
  • Mass: 115778
  • Checksum: 7883B6796E1F0D45
  • Sequence:
    • MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG PSSSPAAAAA 
PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN 
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDAHS VESLTAQNLS LHSGTATPPL 
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE 
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK 
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA 
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL 
VESVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE TQTQLEHARI GELEQSLLLE 
KAQAERLLRE LADNRLTTVA EKSRVLQLEE ELTLRRGEIE ELQQCLLHSG PPPPDHPDAA 
EILRLRERLL SASKEHQRES GVLRDKYEKA LKAYQAEVDK LRAANEKYAQ EVAGLKDKVQ 
QATSENMGLM DNWKSKLDSL ASDHQKSLED LKATLNSGPG AQQKEIGELK AVMEGIKMEH 
QLELGNLQAK HDLETAMHVK EKEALREKLQ EAQEELAGLQ RHWRAQLEVQ ASQHRLELQE 
AQDQRRDAEL RVHELEKLDV EYRGQAQAIE FLKEQISLAE KKMLDYERLQ RAEAQGKQEV 
ESLREKLLVA ENRLQAVEAL CSSQHTHMIE SNDISEETIR TKETVEGLQD KLNKRDKEVT 
ALTSQTEMLR AQVSALESKC KSGEKKVDAL LKEKRRLEAE LETVSRKTHD ASGQLVLISQ 
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI RGLREKLTGL 
DKEKSLSDQR RYSLIDPSSA PELLRLQHQL MSTEDALRDA LDQAQQVEKL MEAMRSCPDK 
AQTIGNSGSA NGIHQQDKAQ KQEDKH

Genular Protein ID: 1012478381

Symbol: A7E2F7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A7E2F7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 5 Gene3D 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1011
  • Mass: 111723
  • Checksum: 2E745BB10115487C
  • Sequence:
    • MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG PSSSPAAAAA 
PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN 
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDAHS VESLTAQNLS LHSGTATPPL 
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE 
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK 
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA 
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL 
VESVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE LTTVAEKSRV LQLEEELTLR 
RGEIEELQQC LLHSGPPPPD HPDAAEILRL RERLLSASKE HQRESGVLRD KYEKALKAYQ 
AEVDKLRAAN EKYAQEVAGL KDKVQQATSE NMGLMDNWKS KLDSLASDHQ KSLEDLKATL 
NSGPGAQQKE IGELKAVMEG IKMEHQLELG NLQAKHDLET AMHVKEKEAL REKLQEAQEE 
LAGLQRHWRA QLEVQASQHR LELQEAQDQR RDAELRVHEL EKLDVEYRGQ AQAIEFLKEQ 
ISLAEKKMLD YERLQRAEAQ GKQEVESLRE KLLVAENRLQ AVEALCSSQH THMIESNDIS 
EETIRTKETV EGLQDKLNKR DKEVTALTSQ TEMLRAQVSA LESKCKSGEK KVDALLKEKR 
RLEAELETVS RKTHDASGQL VLISQELLRK ERSLNELRVL LLEANRHSPG PERDLSREVH 
KAEWRIKEQK LKDDIRGLRE KLTGLDKEKS LSDQRRYSLI DPSSAPELLR LQHQLMSTED 
ALRDALDQAQ QVEKLMEAMR SCPDKAQTIG NSGSANGIHQ QDKAQKQEDK H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.