Details for: CLIP2

Gene ID: 7461

Symbol: CLIP2

Ensembl ID: ENSG00000106665

Description: CAP-Gly domain containing linker protein 2

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 2.74
    Marker Score: 1227
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.19
    Marker Score: 32684.5
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 2.17
    Marker Score: 1268
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 2.16
    Marker Score: 16563
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.01
    Marker Score: 8350
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2
    Marker Score: 7731
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.99
    Marker Score: 18749
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.99
    Marker Score: 39622
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.94
    Marker Score: 71672
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.93
    Marker Score: 118975
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.93
    Marker Score: 73455
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.85
    Marker Score: 1080
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 1.81
    Marker Score: 573
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.76
    Marker Score: 16700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.74
    Marker Score: 14912
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.7
    Marker Score: 3269
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.66
    Marker Score: 35438.5
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 1.64
    Marker Score: 7604.5
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.62
    Marker Score: 938
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.58
    Marker Score: 2438
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.58
    Marker Score: 660
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.56
    Marker Score: 1790
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.53
    Marker Score: 2571
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.47
    Marker Score: 826
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.47
    Marker Score: 169020
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.36
    Marker Score: 2771
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.34
    Marker Score: 3205
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.27
    Marker Score: 489
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.22
    Marker Score: 1353
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 1.22
    Marker Score: 1281
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.2
    Marker Score: 329
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 1.19
    Marker Score: 570
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.11
    Marker Score: 730
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.1
    Marker Score: 17262
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.08
    Marker Score: 1221
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.07
    Marker Score: 1016
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 1.05
    Marker Score: 1275
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.04
    Marker Score: 300
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 1.01
    Marker Score: 2883
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1
    Marker Score: 557.5
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71788
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48013
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.99
    Marker Score: 358
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30405
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.97
    Marker Score: 2275
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.96
    Marker Score: 496
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.95
    Marker Score: 450
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2410
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2732
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.9
    Marker Score: 5136
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 316
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5296
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.87
    Marker Score: 5249
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.87
    Marker Score: 254
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.87
    Marker Score: 432
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.86
    Marker Score: 409
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.85
    Marker Score: 677
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.83
    Marker Score: 3458
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.82
    Marker Score: 257
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.82
    Marker Score: 491
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.8
    Marker Score: 10613.5
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 0.8
    Marker Score: 993
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.79
    Marker Score: 8041
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1262
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.77
    Marker Score: 461.5
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.77
    Marker Score: 1033
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.76
    Marker Score: 580.5
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.75
    Marker Score: 808
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 0.75
    Marker Score: 406
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.75
    Marker Score: 3138
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.75
    Marker Score: 2348
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 386
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.73
    Marker Score: 663
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 0.73
    Marker Score: 815
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.72
    Marker Score: 287
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 0.71
    Marker Score: 877
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.7
    Marker Score: 225
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.68
    Marker Score: 174
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.67
    Marker Score: 1466
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.65
    Marker Score: 245
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 0.65
    Marker Score: 206
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.63
    Marker Score: 281
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.6
    Marker Score: 604
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.58
    Marker Score: 2371
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.58
    Marker Score: 444
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.56
    Marker Score: 2345
  • Cell Name: early lymphoid progenitor (CL0000936)
    Fold Change: 0.55
    Marker Score: 269
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.55
    Marker Score: 1159
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.55
    Marker Score: 435
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.53
    Marker Score: 531
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.52
    Marker Score: 654
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 0.52
    Marker Score: 527
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 0.52
    Marker Score: 174
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.52
    Marker Score: 134
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: 0.51
    Marker Score: 324
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.51
    Marker Score: 3231
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 0.5
    Marker Score: 443
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 0.5
    Marker Score: 339
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.5
    Marker Score: 516
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.49
    Marker Score: 155

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Other Information

**Key Characteristics:** CLIP2 is a small protein encoded by the CLIP2 gene, with a conserved CAP-Gly domain that enables its interaction with microtubules. This domain is essential for its role in regulating cytoskeletal dynamics, particularly at the plus-end of microtubules. The protein's ability to bind microtubules and other cytoskeletal components positions it as a key regulator of cellular morphology and movement. **Pathways and Functions:** CLIP2 is involved in several key cellular pathways, including: 1. **Cell Cortex:** CLIP2 plays a crucial role in maintaining the structural integrity of the cell cortex, which is essential for cell shape, movement, and division. 2. **Cytoplasmic Microtubule Organization:** CLIP2 regulates the dynamics of microtubules, ensuring proper organization and function of the cytoskeleton. 3. **Microtubule Associated Complex:** CLIP2 interacts with other microtubule-associated proteins to form complexes that regulate microtubule function and stability. 4. **Microtubule Binding:** CLIP2's CAP-Gly domain enables its binding to microtubules, which is essential for its role in regulating cytoskeletal dynamics. In addition to its role in regulating cytoskeletal dynamics, CLIP2 has been implicated in various cellular processes, including: * Cell migration and adhesion * Cell division and mitosis * Axonal growth and guidance * Cytoskeletal remodeling **Clinical Significance:** Dysregulation of CLIP2 has been implicated in various disease states, including: 1. **Neurodegenerative Disorders:** CLIP2 has been linked to neurodegenerative diseases such as Alzheimer's and Parkinson's, where dysregulation of the cytoskeleton and microtubules can lead to neuronal dysfunction and death. 2. **Cancer:** CLIP2's role in regulating cell migration and adhesion has made it a potential target for cancer therapy. 3. **Neurodevelopmental Disorders:** CLIP2 has been implicated in neurodevelopmental disorders such as autism and schizophrenia, where dysregulation of the cytoskeleton and microtubules can contribute to cognitive and behavioral deficits. In conclusion, CLIP2 is a multifunctional gene that plays a crucial role in maintaining cellular organization and function. Its dysregulation has been implicated in various disease states, highlighting the need for further research into the mechanisms underlying its function and its potential therapeutic applications. As an expert immunologist, I hope this review has provided a comprehensive understanding of the enigmatic role of CLIP2 in cellular biology and its potential implications for human health.

Genular Protein ID: 2952260555

Symbol: CLIP2_HUMAN

Name: CAP-Gly domain-containing linker protein 2

UniProtKB Accession Codes:

Q9UDT6 O14527 O43611

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 CarbonylDB 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 7 EPD 1 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 RefSeq 2 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9179496

Title: Construction and characterization of human brain cDNA libraries suitable for analysis of cDNA clones encoding relatively large proteins.

PubMed ID: 9179496

DOI: 10.1093/dnares/4.1.53

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 8812460

Title: Identification of genes from a 500-kb region at 7q11.23 that is commonly deleted in Williams syndrome patients.

PubMed ID: 8812460

DOI: 10.1006/geno.1996.0469

PubMed ID: 9799601

Title: The murine CYLN2 gene: genomic organization, chromosome localization, and comparison to the human gene that is located within the 7q11.23 Williams syndrome critical region.

PubMed ID: 9799601

DOI: 10.1006/geno.1998.5529

PubMed ID: 11290329

Title: Clasps are CLIP-115 and -170 associating proteins involved in the regional regulation of microtubule dynamics in motile fibroblasts.

PubMed ID: 11290329

DOI: 10.1016/s0092-8674(01)00288-4

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 22608712

Title: The contribution of CLIP2 haploinsufficiency to the clinical manifestations of the Williams-Beuren syndrome.

PubMed ID: 22608712

DOI: 10.1016/j.ajhg.2012.04.020

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 1046
  • Mass: 115837
  • Checksum: 7A0B3C796E1C6E25
  • Sequence:
    • MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG PSSSPAAAAA 
PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN 
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDAHS VESLTAQNLS LHSGTATPPL 
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE 
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK 
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA 
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL 
VESVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE TQTQLEHARI GELEQSLLLE 
KAQAERLLRE LADNRLTTVA EKSRVLQLEE ELTLRRGEIE ELQQCLLHSG PPPPDHPDAA 
EILRLRERLL SASKEHQRES GVLRDKYEKA LKAYQAEVDK LRAANEKYAQ EVAGLKDKVQ 
QATSENMGLM DNWKSKLDSL ASDHQKSLED LKATLNSGPG AQQKEIGELK AVMEGIKMEH 
QLELGNLQAK HDLETAMHVK EKEALREKLQ EAQEELAGLQ RHWRAQLEVQ ASQHRLELQE 
AQDQRRDAEL RVHELEKLDV EYRGQAQAIE FLKEQISLAE KKMLDYERLQ RAEAQGKQEV 
ESLREKLLVA ENRLQAVEAL CSSQHTHMIE SNDISEETIR TKETVEGLQD KLNKRDKEVT 
ALTSQTEMLR AQVSALESKC KSGEKKVDAL LKEKRRLEAE LETVSRKTHD ASGQLVLISQ 
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI RGLREKLTGL 
DKEKSLSDQR RYSLIDRSSA PELLRLQHQL MSTEDALRDA LDQAQQVEKL MEAMRSCPDK 
AQTIGNSGSA NGIHQQDKAQ KQEDKH

Genular Protein ID: 490495042

Symbol: A0A140VJG6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A140VJG6

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Gene3D 1 GenomeRNAi 1 InterPro 2 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 1046
  • Mass: 115778
  • Checksum: 7883B6796E1F0D45
  • Sequence:
    • MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG PSSSPAAAAA 
PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN 
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDAHS VESLTAQNLS LHSGTATPPL 
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE 
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK 
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA 
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL 
VESVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE TQTQLEHARI GELEQSLLLE 
KAQAERLLRE LADNRLTTVA EKSRVLQLEE ELTLRRGEIE ELQQCLLHSG PPPPDHPDAA 
EILRLRERLL SASKEHQRES GVLRDKYEKA LKAYQAEVDK LRAANEKYAQ EVAGLKDKVQ 
QATSENMGLM DNWKSKLDSL ASDHQKSLED LKATLNSGPG AQQKEIGELK AVMEGIKMEH 
QLELGNLQAK HDLETAMHVK EKEALREKLQ EAQEELAGLQ RHWRAQLEVQ ASQHRLELQE 
AQDQRRDAEL RVHELEKLDV EYRGQAQAIE FLKEQISLAE KKMLDYERLQ RAEAQGKQEV 
ESLREKLLVA ENRLQAVEAL CSSQHTHMIE SNDISEETIR TKETVEGLQD KLNKRDKEVT 
ALTSQTEMLR AQVSALESKC KSGEKKVDAL LKEKRRLEAE LETVSRKTHD ASGQLVLISQ 
ELLRKERSLN ELRVLLLEAN RHSPGPERDL SREVHKAEWR IKEQKLKDDI RGLREKLTGL 
DKEKSLSDQR RYSLIDPSSA PELLRLQHQL MSTEDALRDA LDQAQQVEKL MEAMRSCPDK 
AQTIGNSGSA NGIHQQDKAQ KQEDKH

Genular Protein ID: 1012478381

Symbol: A7E2F7_HUMAN

Name: N/A

UniProtKB Accession Codes:

A7E2F7

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Gene3D 1 GenomeRNAi 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1011
  • Mass: 111723
  • Checksum: 2E745BB10115487C
  • Sequence:
    • MQKPSGLKPP GRGGKHSSPM GRTSTGSASS SAAVAASSKE GSPLHKQSSG PSSSPAAAAA 
PEKPGPKAAE VGDDFLGDFV VGERVWVNGV KPGVVQYLGE TQFAPGQWAG VVLDDPVGKN 
DGAVGGVRYF ECPALQGIFT RPSKLTRQPT AEGSGSDAHS VESLTAQNLS LHSGTATPPL 
TSRVIPLRES VLNSSVKTGN ESGSNLSDSG SVKRGEKDLR LGDRVLVGGT KTGVVRYVGE 
TDFAKGEWCG VELDEPLGKN DGAVAGTRYF QCPPKFGLFA PIHKVIRIGF PSTSPAKAKK 
TKRMAMGVSA LTHSPSSSSI SSVSSVASSV GGRPSRSGLL TETSSRYARK ISGTTALQEA 
LKEKQQHIEQ LLAERDLERA EVAKATSHIC EVEKEIALLK AQHEQYVAEA EEKLQRARLL 
VESVRKEKVD LSNQLEEERR KVEDLQFRVE EESITKGDLE LTTVAEKSRV LQLEEELTLR 
RGEIEELQQC LLHSGPPPPD HPDAAEILRL RERLLSASKE HQRESGVLRD KYEKALKAYQ 
AEVDKLRAAN EKYAQEVAGL KDKVQQATSE NMGLMDNWKS KLDSLASDHQ KSLEDLKATL 
NSGPGAQQKE IGELKAVMEG IKMEHQLELG NLQAKHDLET AMHVKEKEAL REKLQEAQEE 
LAGLQRHWRA QLEVQASQHR LELQEAQDQR RDAELRVHEL EKLDVEYRGQ AQAIEFLKEQ 
ISLAEKKMLD YERLQRAEAQ GKQEVESLRE KLLVAENRLQ AVEALCSSQH THMIESNDIS 
EETIRTKETV EGLQDKLNKR DKEVTALTSQ TEMLRAQVSA LESKCKSGEK KVDALLKEKR 
RLEAELETVS RKTHDASGQL VLISQELLRK ERSLNELRVL LLEANRHSPG PERDLSREVH 
KAEWRIKEQK LKDDIRGLRE KLTGLDKEKS LSDQRRYSLI DPSSAPELLR LQHQLMSTED 
ALRDALDQAQ QVEKLMEAMR SCPDKAQTIG NSGSANGIHQ QDKAQKQEDK H

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.