Details for: ZNF79

Gene ID: 7633

Symbol: ZNF79

Ensembl ID: ENSG00000196152

Description: zinc finger protein 79

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.48
    Marker Score: 169639
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71816
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48041
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30408
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 501
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 454
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2412
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 0.92
    Marker Score: 1879
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.92
    Marker Score: 5232
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2735
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.88
    Marker Score: 598.5
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.88
    Marker Score: 318
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5282
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.77
    Marker Score: 1254
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 701
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.75
    Marker Score: 389
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.74
    Marker Score: 11642
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.73
    Marker Score: 559
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.7
    Marker Score: 282
  • Cell Name: choroid plexus epithelial cell (CL0000706)
    Fold Change: 0.69
    Marker Score: 637
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.69
    Marker Score: 1314
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.69
    Marker Score: 1203
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.68
    Marker Score: 2856.5
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.67
    Marker Score: 172
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.64
    Marker Score: 288
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.56
    Marker Score: 2175
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 444
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.53
    Marker Score: 1500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.53
    Marker Score: 337
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 0.51
    Marker Score: 1212
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.41
    Marker Score: 637
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.4
    Marker Score: 130
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.39
    Marker Score: 123
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.39
    Marker Score: 2321
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.38
    Marker Score: 180
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.38
    Marker Score: 226
  • Cell Name: primordial germ cell (CL0000670)
    Fold Change: 0.34
    Marker Score: 430
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 0.34
    Marker Score: 139
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.34
    Marker Score: 3511
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 0.34
    Marker Score: 576.5
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.33
    Marker Score: 2834
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.32
    Marker Score: 134
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.32
    Marker Score: 3027
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.31
    Marker Score: 19160
  • Cell Name: oogonial cell (CL0000024)
    Fold Change: 0.3
    Marker Score: 433
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 0.29
    Marker Score: 2742
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.27
    Marker Score: 120
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 0.26
    Marker Score: 1094
  • Cell Name: natural killer cell (CL0000623)
    Fold Change: 0.26
    Marker Score: 334
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 0.25
    Marker Score: 461
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.25
    Marker Score: 249
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.25
    Marker Score: 9134
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 0.24
    Marker Score: 118
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.24
    Marker Score: 193
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.24
    Marker Score: 159
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 0.23
    Marker Score: 74
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.23
    Marker Score: 504
  • Cell Name: oocyte (CL0000023)
    Fold Change: 0.22
    Marker Score: 54
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.22
    Marker Score: 62
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.22
    Marker Score: 56
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 0.21
    Marker Score: 74
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: 0.21
    Marker Score: 106
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.21
    Marker Score: 811
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.21
    Marker Score: 71
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.21
    Marker Score: 4451
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.21
    Marker Score: 142
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.21
    Marker Score: 149
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.2
    Marker Score: 54
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.2
    Marker Score: 4029
  • Cell Name: neuron (CL0000540)
    Fold Change: 0.2
    Marker Score: 803
  • Cell Name: T-helper 17 cell (CL0000899)
    Fold Change: 0.2
    Marker Score: 128
  • Cell Name: retinal pigment epithelial cell (CL0002586)
    Fold Change: 0.19
    Marker Score: 55
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 0.18
    Marker Score: 2756
  • Cell Name: male germ cell (CL0000015)
    Fold Change: 0.18
    Marker Score: 53
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.18
    Marker Score: 6759
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.18
    Marker Score: 603
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.17
    Marker Score: 720
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.17
    Marker Score: 78
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.17
    Marker Score: 328
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.17
    Marker Score: 206
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 0.16
    Marker Score: 1246
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.16
    Marker Score: 171
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 0.16
    Marker Score: 141
  • Cell Name: progenitor cell of endocrine pancreas (CL0002351)
    Fold Change: 0.16
    Marker Score: 34
  • Cell Name: melanocyte (CL0000148)
    Fold Change: 0.16
    Marker Score: 63
  • Cell Name: B cell (CL0000236)
    Fold Change: 0.15
    Marker Score: 147
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 0.15
    Marker Score: 64
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 0.15
    Marker Score: 86
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.15
    Marker Score: 103
  • Cell Name: PP cell (CL0000696)
    Fold Change: 0.15
    Marker Score: 34
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.15
    Marker Score: 33
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.15
    Marker Score: 69
  • Cell Name: NKp44-negative group 3 innate lymphoid cell, human (CL0001080)
    Fold Change: 0.15
    Marker Score: 33
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.15
    Marker Score: 622
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.15
    Marker Score: 37
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 0.15
    Marker Score: 74
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 0.15
    Marker Score: 171
  • Cell Name: stromal cell of lamina propria of small intestine (CL0009022)
    Fold Change: 0.15
    Marker Score: 33
  • Cell Name: activated CD8-positive, alpha-beta T cell, human (CL0001049)
    Fold Change: 0.15
    Marker Score: 33
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: 0.14
    Marker Score: 146

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Other Information

**Key Characteristics:** 1. **Transcriptional Regulation**: ZNF79 is a transcription factor that regulates gene expression by interacting with RNA polymerase II, a crucial enzyme in the transcriptional machinery. 2. **DNA Binding**: The protein is predicted to bind to specific DNA sequences, allowing it to regulate transcriptional activity. 3. **Cellular Expression**: ZNF79 is significantly expressed in cells of the nervous system, immune cells, and epithelial tissues, including mural cells, cerebral cortex GABAergic interneurons, and intestinal epithelial cells. 4. **Multiple Biological Processes**: The protein's expression is associated with various biological processes, including immune response, development, and tissue homeostasis. **Pathways and Functions:** 1. **DNA-Binding Transcription Factor Activity**: ZNF79 regulates transcription by binding to specific DNA sequences, interacting with RNA polymerase II, and influencing gene expression. 2. **RNA Polymerase II-Specific Transcription**: The protein interacts with RNA polymerase II, a key enzyme in the transcriptional machinery, to regulate transcriptional activity. 3. **Gene Expression (Transcription)**: ZNF79 regulates gene expression by controlling the transcription of specific genes, influencing cellular differentiation, development, and tissue homeostasis. 4. **Metal Ion Binding**: The protein is predicted to bind to metal ions, which may influence its transcriptional activity and interactions with other proteins. **Clinical Significance:** 1. **Immune Response**: ZNF79's expression in immune cells, including immature innate lymphoid cells, suggests its involvement in immune response and regulation. 2. **Neurological Disorders**: The protein's expression in cerebral cortex GABAergic interneurons and other nervous system cells may be associated with neurological disorders, such as epilepsy and schizophrenia. 3. **Cancer**: ZNF79's expression in epithelial tissues, including intestinal epithelial cells, may be linked to cancer development and progression. 4. **Developmental Disorders**: The protein's expression in embryonic cells, including forebrain radial glial cells, suggests its involvement in developmental processes and may be associated with developmental disorders, such as autism spectrum disorder. In conclusion, ZNF79 is a transcriptional regulator that plays a crucial role in regulating gene expression in various cell types, including immune cells, nervous system cells, and epithelial tissues. Its expression is associated with multiple biological processes, including immune response, development, and tissue homeostasis. Further studies are needed to elucidate the protein's mechanisms of action, its role in disease, and its potential as a therapeutic target.

Genular Protein ID: 2832289137

Symbol: ZNF79_HUMAN

Name: Zinc finger protein 79

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8478004

Title: Chromosomal localization of four human zinc finger cDNAs.

PubMed ID: 8478004

DOI: 10.1007/bf00218259

Sequence Information:

  • Length: 498
  • Mass: 55350
  • Checksum: 6E4A9F5AE680BF0C
  • Sequence:
  • MLEEGVLPSP GPALPQEENT GEEGMAAGLL TAGPRGSTFF SSVTVAFAQE RWRCLVSTPR 
    DRFKEGIPGK SRSLVLLGLP VSQPGMNSQL EQREGAWMLE GEDLRSPSPG WKIISGSPPE 
    QALSEASFQD PCVEMPPGDS DHGTSDLEKS FNLRPVLSPQ QRVPVEARPR KCETHTESFK 
    NSEILKPHRA KPYACNECGK AFSYCSSLSQ HQKSHTGEKP YECSECGKAF SQSSSLIQHQ 
    RIHTGEKPYK CSECGRAFSQ NANLTKHQRT HTGEKPYRCS ECEKAFSDCS ALVQHQRIHT 
    GEKPYECSDC GKAFRHSANL TNHQRTHTGE KPYKCSECGK AFSYCAAFIQ HQRIHTGEKP 
    YRCAACGKAF SQSANLTNHQ RTHTGEKPYK CSECGKAFSQ STNLIIHQKT HTGEKPYKCN 
    ECGKFFSESS ALIRHHIIHT GEKPYECNEC GKAFNQSSSL SQHQRIHTGV KPYECSECGK 
    AFRCSSAFVR HQRLHAGE

Genular Protein ID: 1213866582

Symbol: B7ZAB8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 474
  • Mass: 52970
  • Checksum: 32753F64152AAAA8
  • Sequence:
  • MAAGLLTAGP RGSTFFSSVT VAFAQERWRC LVSTPRDRFK EGIPGKSRSL VLLGLPVSQP 
    GMNSQLEQRE GAWMLEGEDL RSPSPGWKII SGSPPEQALS EASFQDPCVE MPPGDSDHGT 
    SDLEKSFNLR PVLSPQQRVP VEARPRKCET HTESFKNSEI LKPHRAKPYA CNECGKAFSY 
    CSSLSQHQKS HTGEKPYECS ECGKAFSQSS SLIQHQRIHT GEKPYKCSEC GRAFSQNANL 
    TKHQRTHTGE KPYRCSECEK AFSDCSALVQ HQRIHTGEKP YECSDWGKAF RHSANLTNHQ 
    RTHTGEKPYK CSECGKAFSY CAAFIQHQRI HTGEKPYRCA ACGKAFSQSA NLTNHQRTHT 
    GEKPYKCSEC GKAFSQSTNL IIHQKTHTGE KPYKCNECGK FFSESSALIR HHIIHTGEKP 
    YECNECGKAF NQSSSLSQHQ RIHTGVKPYE CSECGKAFRC SSAFVRHQRL HAGE

Genular Protein ID: 3226498728

Symbol: A0A087X2B0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

Sequence Information:

  • Length: 364
  • Mass: 40999
  • Checksum: 12CDAC94ADE81EF5
  • Sequence:
  • MPPGDSDHGT SDLEKSFNLR PVLSPQQRVP VEARPRKCET HTESFKNSEI LKPHRAKPYA 
    CNECGKAFSY CSSLSQHQKS HTGEKPYECS ECGKAFSQSS SLIQHQRIHT GEKPYKCSEC 
    GRAFSQNANL TKHQRTHTGE KPYRCSECEK AFSDCSALVQ HQRIHTGEKP YECSDCGKAF 
    RHSANLTNHQ RTHTGEKPYK CSECGKAFSY CAAFIQHQRI HTGEKPYRCA ACGKAFSQSA 
    NLTNHQRTHT GEKPYKCSEC GKAFSQSTNL IIHQKTHTGE KPYKCNECGK FFSESSALIR 
    HHIIHTGEKP YECNECGKAF NQSSSLSQHQ RIHTGVKPYE CSECGKAFRC SSAFVRHQRL 
    HAGE

Genular Protein ID: 1863963270

Symbol: F5H032_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

Sequence Information:

  • Length: 474
  • Mass: 52887
  • Checksum: 8AECFF79DCFEA375
  • Sequence:
  • MAAGLLTAGP RGSTFFSSVT VAFAQERWRC LVSTPRDRFK EGIPGKSRSL VLLGLPVSQP 
    GMNSQLEQRE GAWMLEGEDL RSPSPGWKII SGSPPEQALS EASFQDPCVE MPPGDSDHGT 
    SDLEKSFNLR PVLSPQQRVP VEARPRKCET HTESFKNSEI LKPHRAKPYA CNECGKAFSY 
    CSSLSQHQKS HTGEKPYECS ECGKAFSQSS SLIQHQRIHT GEKPYKCSEC GRAFSQNANL 
    TKHQRTHTGE KPYRCSECEK AFSDCSALVQ HQRIHTGEKP YECSDCGKAF RHSANLTNHQ 
    RTHTGEKPYK CSECGKAFSY CAAFIQHQRI HTGEKPYRCA ACGKAFSQSA NLTNHQRTHT 
    GEKPYKCSEC GKAFSQSTNL IIHQKTHTGE KPYKCNECGK FFSESSALIR HHIIHTGEKP 
    YECNECGKAF NQSSSLSQHQ RIHTGVKPYE CSECGKAFRC SSAFVRHQRL HAGE

Genular Protein ID: 3145024691

Symbol: B4DY65_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 474
  • Mass: 52800
  • Checksum: A768197E357B0709
  • Sequence:
  • MAAGLLIAGP RGSTFFSSVT VAFAQEGWRC LVSTPRDRFK EGIPGKSRSL VLLGLPVSQP 
    GMNSQLEQRE GAWMLEGEDL RSPSPGWKII SGSPPEQALS EASFQDPCVE MPPGDSDHGT 
    SDLEKSFNLR PVLSPQQRVP VEARPRKCET HTESFKNSEI LKPHRAKPYA CNECGKAFSY 
    CSSLSQHQKS HTGEKPYECS ECGKAFSQSS SLIQHQRIHT GEKPYKCSEC GRAFSQNANL 
    TKHQRTHTGE KPYRCSECEK AFSDCSALVQ HQRIHTGEKP YECSDCGKAF RHSANLTNHQ 
    RTHTGEKPYK CSECGKAFSY CAAFIQHQRI HTGEKPYRCA ACGKAFSQSA NLTNHQRTHT 
    GEKPYKCSEC GKAFSQSTNL IIHQKTHTGE KPYKCNECGK FFSESSALIR HHIIHTGEKP 
    YECNECGKAF NQSSSLSQHQ RIHTGVKPYE CSECGKAFRC SSAFVRHQRL HAGE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.