Details for: ZMYM2
Gene ID: 7750
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: ZMYM2
Ensembl ID: ENSG00000121741
Description: zinc finger MYM-type containing 2
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
-
CSI 49.92rCSI 83.79%PRS 12.53
-
CSI 48.67rCSI 60.54%PRS 11.7
-
CSI 46.23rCSI 74.35%PRS 13.67
-
CSI 41.67rCSI 53.72%PRS 13.1
-
CSI 38.75rCSI 46.28%PRS 12.33
-
CSI 35.38rCSI 85.98%PRS 12.25
-
CSI 32.79rCSI 57.9%PRS 12.43
-
CSI 29.88rCSI 42.35%PRS 19.56
-
CSI 28rCSI 60.74%PRS 15.23
-
CSI 27.66rCSI 86.43%PRS 13.35
-
CSI 25.7rCSI 68.43%PRS 18.37
-
CSI 25.06rCSI 78.37%PRS 14.36
-
CSI 22.75rCSI 81.86%PRS 11.76
-
CSI 22.13rCSI 83.65%PRS 12.91
-
CSI 22.03rCSI 40.04%PRS 18.01
-
CSI 19.66rCSI 28.21%PRS 16.39
-
CSI 18.13rCSI 43.36%PRS 14
-
CSI 17.06rCSI 19.7%PRS 18.45
-
CSI 16.94rCSI 58.04%PRS 18.48
-
CSI 16rCSI 70.32%PRS 19.44
-
CSI 15.42rCSI 34.07%PRS 15.1
-
CSI 15.09rCSI 49.58%PRS 13.81
-
CSI 14.03rCSI 82.6%PRS 13.11
-
CSI 13.85rCSI 35.14%PRS 16.02
-
CSI 13.11rCSI 16.83%PRS 20.55
-
CSI 12.7rCSI 19.4%PRS 21.3
-
CSI 12.62rCSI 85.9%PRS 22.52
-
CSI 12.43rCSI 22.24%PRS 19.54
-
CSI 12.18rCSI 15.63%PRS 20.39
-
CSI 12.06rCSI 26.55%PRS 17.75
-
CSI 11.75rCSI 44.03%PRS 17.79
-
CSI 11.43rCSI 15.28%PRS 27.33
-
CSI 11.35rCSI 67.06%PRS 23
-
CSI 11.3rCSI 83.09%PRS 12.63
-
CSI 11.23rCSI 55.83%PRS 22.91
-
CSI 11.1rCSI 17.87%PRS 16.14
-
CSI 10.91rCSI 72.45%PRS 22.93
-
CSI 10.56rCSI 55.55%PRS 25.35
-
CSI 10.49rCSI 31.14%PRS 29.57
-
CSI 10.35rCSI 21.48%PRS 21.07
-
CSI 10.11rCSI 15.25%PRS 21.49
-
CSI 10.02rCSI 10.38%PRS 24.91
-
CSI 9.93rCSI 46.72%PRS 23.31
-
CSI 9.9rCSI 17.8%PRS 17.48
-
CSI 9.88rCSI 39.13%PRS 28.49
-
CSI 9.73rCSI 21.53%PRS 19.6
-
CSI 9.6rCSI 15.72%PRS 16.23
-
CSI 9.53rCSI 20.97%PRS 31.92
-
CSI 8.8rCSI 12.94%PRS 19.52
-
CSI 8.8rCSI 68.16%PRS 23.31
-
CSI 8.75rCSI 23.57%PRS 27.4
-
CSI 8.36rCSI 17.68%PRS 41.78
-
CSI 8.35rCSI 16.52%PRS 49.75
-
CSI 8.32rCSI 71.72%PRS 10.98
-
CSI 8.32rCSI 11.56%PRS 21.55
-
CSI 8.17rCSI 58.37%PRS 22.43
-
CSI 8.15rCSI 61.27%PRS 22.21
-
CSI 7.82rCSI 17.14%PRS 28.22
-
CSI 7.77rCSI 20.77%PRS 17.62
-
CSI 7.7rCSI 6.48%PRS 33.27
-
CSI 7.4rCSI 11.81%PRS 18.08
-
CSI 7.4rCSI 6.83%PRS 22
-
CSI 7.34rCSI 11.67%PRS 17.84
-
CSI 7.33rCSI 12.07%PRS 24.97
-
CSI 7.25rCSI 6.21%PRS 34.27
-
CSI 7.13rCSI 57.98%PRS 21.15
-
CSI 7.11rCSI 13.42%PRS 26.76
-
CSI 7.01rCSI 16.32%PRS 41.27
-
CSI 7rCSI 14.38%PRS 20.91
-
CSI 6.81rCSI 57.35%PRS 23.22
-
CSI 6.79rCSI 17.72%PRS 32.21
-
CSI 6.67rCSI 13.39%PRS 15.65
-
CSI 6.28rCSI 18.56%PRS 20.14
-
CSI 6.15rCSI 30.33%PRS 28.52
-
CSI 5.93rCSI 15.44%PRS 21.31
-
CSI 5.81rCSI 7.45%PRS 24.46
-
CSI 5.75rCSI 13.14%PRS 20.6
-
CSI 5.66rCSI 36.26%PRS 32.46
-
CSI 5.65rCSI 7.09%PRS 27.42
-
CSI 5.53rCSI 18.73%PRS 21.98
-
CSI 5.46rCSI 3.63%PRS 25.3
-
CSI 5.44rCSI 4.3%PRS 14.53
-
CSI 5.4rCSI 76.68%PRS 16.34
-
CSI 5.21rCSI 3.74%PRS 29.17
-
CSI 5.15rCSI 9.91%PRS 47.03
-
CSI 4.96rCSI 9.29%PRS 15.19
-
CSI 4.88rCSI 15.04%PRS 31.42
-
CSI 4.88rCSI 11.13%PRS 18.17
-
CSI 4.8rCSI 7.66%PRS 23.14
-
CSI 4.79rCSI 4.61%PRS 21.87
-
CSI 4.7rCSI 15.3%PRS 25.87
-
CSI 4.65rCSI 8.2%PRS 20.64
-
CSI 4.53rCSI 5.64%PRS 29.97
-
CSI 4.53rCSI 11.06%PRS 20.77
-
CSI 4.45rCSI 3.09%PRS 25.4
-
CSI 4.45rCSI 70.14%PRS 19.57
-
CSI 4.42rCSI 3.36%PRS 27.99
-
CSI 4.21rCSI 3.53%PRS 25.08
-
CSI 4.19rCSI 3.68%PRS 15.39
-
CSI 4.17rCSI 5.19%PRS 22.52
-
CSI -2.9rCSI -2.2%PRS 35.4%
-
CSI -2.3rCSI -2.3%PRS 32.8%
-
CSI -0.2rCSI -0.2%PRS 42.3%
-
CSI -0.2rCSI -0.4%PRS 21.2%
-
CSI 0.0rCSI 0.2%PRS 37.2%
-
CSI 0.1rCSI 2.1%PRS 73.9%
-
CSI 0.2rCSI 1.0%PRS 31.0%
-
CSI 0.2rCSI 2.7%PRS 48.4%
-
CSI 0.2rCSI 1.2%PRS 31.5%
-
CSI 0.2rCSI 2.6%PRS 40.0%
-
CSI 0.2rCSI 0.4%PRS 50.4%
-
CSI 0.3rCSI 1.0%PRS 30.1%
-
CSI 0.3rCSI 1.0%PRS 34.2%
-
CSI 0.3rCSI 1.2%PRS 38.3%
-
CSI 0.3rCSI 1.7%PRS 31.2%
-
CSI 0.3rCSI 5.0%PRS 49.6%
-
CSI 0.3rCSI 1.8%PRS 36.9%
-
CSI 0.3rCSI 2.1%PRS 45.8%
-
CSI 0.3rCSI 0.9%PRS 33.2%
-
CSI 0.4rCSI 0.9%PRS 40.6%
-
CSI 0.4rCSI 1.7%PRS 36.5%
-
CSI 0.4rCSI 1.7%PRS 49.7%
-
CSI 0.4rCSI 0.8%PRS 44.0%
-
CSI 0.5rCSI 0.6%PRS 23.2%
-
CSI 0.5rCSI 0.4%PRS 37.7%
-
CSI 0.5rCSI 0.8%PRS 21.2%
-
CSI 0.5rCSI 2.4%PRS 14.3%
-
CSI 0.5rCSI 2.5%PRS 51.0%
-
CSI 0.5rCSI 0.7%PRS 18.5%
-
CSI 0.6rCSI 2.9%PRS 28.0%
-
CSI 0.6rCSI 1.2%PRS 22.2%
-
CSI 0.6rCSI 2.3%PRS 35.9%
-
CSI 0.6rCSI 0.7%PRS 15.6%
-
CSI 0.6rCSI 4.0%PRS 44.8%
-
CSI 0.6rCSI 2.9%PRS 43.5%
-
CSI 0.6rCSI 2.4%PRS 40.9%
-
CSI 0.7rCSI 1.0%PRS 19.7%
-
CSI 0.7rCSI 3.5%PRS 35.2%
-
CSI 0.7rCSI 0.9%PRS 29.3%
-
CSI 0.7rCSI 0.7%PRS 19.5%
-
CSI 0.7rCSI 4.3%PRS 60.6%
-
CSI 0.7rCSI 1.7%PRS 33.5%
-
CSI 0.7rCSI 4.4%PRS 16.5%
-
CSI 0.7rCSI 2.7%PRS 36.3%
-
CSI 0.7rCSI 0.8%PRS 22.0%
-
CSI 0.8rCSI 0.5%PRS 29.6%
-
CSI 0.8rCSI 1.2%PRS 24.1%
-
CSI 0.8rCSI 1.0%PRS 25.4%
-
CSI 0.8rCSI 2.8%PRS 60.3%
-
CSI 0.8rCSI 0.8%PRS 22.2%
-
CSI 0.8rCSI 7.2%PRS 15.4%
-
CSI 0.8rCSI 5.9%PRS 23.9%
-
CSI 0.8rCSI 2.7%PRS 53.9%
-
CSI 0.9rCSI 4.0%PRS 41.8%
-
CSI 0.9rCSI 0.7%PRS 26.6%
-
CSI 0.9rCSI 0.8%PRS 19.1%
-
CSI 0.9rCSI 1.5%PRS 27.6%
-
CSI 0.9rCSI 0.9%PRS 22.5%
-
CSI 0.9rCSI 1.1%PRS 36.5%
-
CSI 0.9rCSI 2.6%PRS 35.3%
-
CSI 0.9rCSI 0.6%PRS 26.1%
-
CSI 0.9rCSI 5.6%PRS 36.9%
-
CSI 0.9rCSI 1.8%PRS 21.7%
-
CSI 0.9rCSI 2.6%PRS 19.8%
-
CSI 1.0rCSI 0.8%PRS 23.9%
-
CSI 1.0rCSI 1.1%PRS 36.7%
-
CSI 1.0rCSI 1.2%PRS 32.4%
-
CSI 1.0rCSI 2.0%PRS 31.4%
-
CSI 1.0rCSI 2.6%PRS 27.1%
-
CSI 1.0rCSI 1.0%PRS 22.8%
-
CSI 1.0rCSI 4.8%PRS 45.4%
-
CSI 1.0rCSI 1.6%PRS 27.2%
-
CSI 1.0rCSI 5.6%PRS 47.6%
-
CSI 1.0rCSI 9.0%PRS 32.3%
-
CSI 1.1rCSI 1.4%PRS 32.5%
-
CSI 1.1rCSI 2.1%PRS 35.2%
-
CSI 1.1rCSI 2.5%PRS 26.1%
-
CSI 1.1rCSI 1.5%PRS 30.2%
-
CSI 1.1rCSI 8.4%PRS 38.3%
-
CSI 1.1rCSI 4.4%PRS 34.7%
-
CSI 1.2rCSI 1.2%PRS 19.7%
-
CSI 1.2rCSI 2.2%PRS 40.8%
-
CSI 1.2rCSI 2.5%PRS 32.4%
-
CSI 1.2rCSI 3.3%PRS 31.6%
-
CSI 1.2rCSI 4.0%PRS 15.2%
-
CSI 1.2rCSI 2.9%PRS 37.5%
-
CSI 1.2rCSI 1.2%PRS 18.1%
-
CSI 1.2rCSI 1.5%PRS 24.5%
-
CSI 1.2rCSI 1.0%PRS 21.2%
-
CSI 1.2rCSI 6.9%PRS 12.0%
-
CSI 1.2rCSI 6.8%PRS 51.3%
-
CSI 1.2rCSI 1.9%PRS 24.1%
-
CSI 1.2rCSI 2.6%PRS 33.4%
-
CSI 1.3rCSI 3.7%PRS 20.3%
-
CSI 1.3rCSI 1.8%PRS 31.9%
-
CSI 1.3rCSI 1.3%PRS 35.9%
-
CSI 1.3rCSI 1.0%PRS 22.3%
-
CSI 1.3rCSI 1.8%PRS 23.9%
-
CSI 1.3rCSI 1.7%PRS 23.2%
-
CSI 1.3rCSI 6.8%PRS 36.0%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 623713671
Symbol: ZMYM2_HUMAN
Name: Zinc finger MYM-type protein 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9576949
Title: Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)(p12;q12).
PubMed ID: 9576949
PubMed ID: 9716603
Title: Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome.
PubMed ID: 9716603
PubMed ID: 9889006
Title: The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome.
PubMed ID: 9889006
PubMed ID: 11230166
Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.
PubMed ID: 11230166
DOI: 10.1101/gr.gr1547r
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9694738
Title: The t(8;13) atypical myeloproliferative disorder: further analysis of the ZNF198 gene and lack of evidence for multiple genes disrupted on chromosome 13.
PubMed ID: 9694738
PubMed ID: 9499416
Title: The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP.
PubMed ID: 9499416
DOI: 10.1093/hmg/7.4.637
PubMed ID: 9425908
Title: FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome.
PubMed ID: 9425908
DOI: 10.1038/ng0198-84
PubMed ID: 12493763
Title: A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.
PubMed ID: 12493763
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 25218447
Title: Uncovering global SUMOylation signaling networks in a site-specific manner.
PubMed ID: 25218447
DOI: 10.1038/nsmb.2890
PubMed ID: 25772364
Title: SUMO-2 orchestrates chromatin modifiers in response to DNA damage.
PubMed ID: 25772364
PubMed ID: 25755297
Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
PubMed ID: 25755297
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 32891193
Title: Mutations of the transcriptional corepressor ZMYM2 cause syndromic urinary tract malformations.
PubMed ID: 32891193
Sequence Information:
- Length: 1377
- Mass: 154911
- Checksum: 2652D4C766492FF9
- Sequence:
MDTSSVGGLE LTDQTPVLLG STAMATSLTN VGNSFSGPAN PLVSRSNKFQ NSSVEDDDDV VFIEPVQPPP PSVPVVADQR TITFTSSKNE ELQGNDSKIT PSSKELASQK GSVSETIVID DEEDMETNQG QEKNSSNFIE RRPPETKNRT NDVDFSTSSF SRSKVNAGMG NSGITTEPDS EIQIANVTTL ETGVSSVNDG QLENTDGRDM NLMITHVTSL QNTNLGDVSN GLQSSNFGVN IQTYTPSLTS QTKTGVGPFN PGRMNVAGDV FQNGESATHH NPDSWISQSA SFPRNQKQPG VDSLSPVASL PKQIFQPSVQ QQPTKPVKVT CANCKKPLQK GQTAYQRKGS AHLFCSTTCL SSFSHKPAPK KLCVMCKKDI TTMKGTIVAQ VDSSESFQEF CSTSCLSLYE DKQNPTKGAL NKSRCTICGK LTEIRHEVSF KNMTHKLCSD HCFNRYRMAN GLIMNCCEQC GEYLPSKGAG NNVLVIDGQQ KRFCCQSCVS EYKQVGSHPS FLKEVRDHMQ DSFLMQPEKY GKLTTCTGCR TQCRFFDMTQ CIGPNGYMEP YCSTACMNSH KTKYAKSQSL GIICHFCKRN SLPQYQATMP DGKLYNFCNS SCVAKFQALS MQSSPNGQFV APSDIQLKCN YCKNSFCSKP EILEWENKVH QFCSKTCSDD YKKLHCIVTY CEYCQEEKTL HETVNFSGVK RPFCSEGCKL LYKQDFARRL GLRCVTCNYC SQLCKKGATK ELDGVVRDFC SEDCCKKFQD WYYKAARCDC CKSQGTLKER VQWRGEMKHF CDQHCLLRFY CQQNEPNMTT QKGPENLHYD QGCQTSRTKM TGSAPPPSPT PNKEMKNKAV LCKPLTMTKA TYCKPHMQTK SCQTDDTWRT EYVPVPIPVP VYIPVPMHMY SQNIPVPTTV PVPVPVPVFL PAPLDSSEKI PAAIEELKSK VSSDALDTEL LTMTDMMSED EGKTETTNIN SVIIETDIIG SDLLKNSDPE TQSSMPDVPY EPDLDIEIDF PRAAEELDME NEFLLPPVFG EEYEEQPRPR SKKKGAKRKA VSGYQSHDDS SDNSECSFPF KYTYGVNAWK HWVKTRQLDE DLLVLDELKS SKSVKLKEDL LSHTTAELNY GLAHFVNEIR RPNGENYAPD SIYYLCLGIQ EYLCGSNRKD NIFIDPGYQT FEQELNKILR SWQPSILPDG SIFSRVEEDY LWRIKQLGSH SPVALLNTLF YFNTKYFGLK TVEQHLRLSF GTVFRHWKKN PLTMENKACL RYQVSSLCGT DNEDKITTGK RKHEDDEPVF EQIENTANPS RCPVKMFECY LSKSPQNLNQ RMDVFYLQPE CSSSTDSPVW YTSTSLDRNT LENMLVRVLL VKDIYDKDNY ELDEDTD
Genular Protein ID: 2763408984
Symbol: A8K126_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1247
- Mass: 139732
- Checksum: E7F36D42D7477F45
- Sequence:
MDTSSVGGLE LTDQTPVLLG STAMATSLTN VGNSLSGPAN PLVSRSNKFQ NSSVEDDDDV VFIEPVQPPP PSVPVVADQR TITFTSSKNE ELQGNDSKIT PSSKELASQK GSVSETIVID DEEDMETNQG QEKNSSNFIE RRPPETKNRT NDVDFSTSSF SRSKVNAGMG NSGITTEPDS EIQIANVTTL ETGVSSVNDG QLENTDGRDM NLMITHVTSL QNTNLGDVSN GLQSSNFGVN IQTYTPSLTS QTKTGVGPFN PGRMNVAGDV FQNGESATHH NPDSWISQSA SFPRNQKQPG VDSLSPVASL PKQIFQPSVQ QQPTKPVKVT CANCKKPLQK GQTAYQRKGS AHLFCSTTCL SSFSHKPAPK KLCVMCKKDI TTMKGTIVAQ VDSSESFQEF CSTSCLSLYE DKQNPTKGAL NKSRCTICGK LTEIRHEVSF KNMTHKLCSD HCFNRYRMAN GLIMNCCEQC GEYLPSKGAG NNVLVIDGQQ KRFCCQSCVS EYKQVGSHPS FLKEVRDHMQ DSFLMQPDKY GKLTTCTGCR TQCRFFDMTQ CIGPNGYMEP YCSTACMNSH KTKYAKSQSL GIICHFCKRN SLPQYQATMP DGKLYNFCNS SCVAKFQALS MQSSPNGQFV APSDIQLKCN YCKNSFCSKP EILEWENKVH QFCSKTCSDD YKKLHCIVTY CEYCQEEKTL HETVNFSGVK RPFCSEGCKL LYKQDFARRL GLRCVTCNYC SQLCKKGATK ELDGVVRDFC SEDCCKKFQD WYYKAARCDC CKSQGTLKER VQWRGEMKHF CDQHCLLRLY CQQNEPNMTT QKGPENLHYD QGCQTSRTKM TGSAPPPSPT PNKEMKNKAV LCKPLTMTKA TYCKPHMQTK SCQTDDTWRT EYVPVPIPVP VYIPVPMHMY SQNIPVPTTV PVPVPVPVFL PAPLDSSEKI PAAIEELKSK VSSDALDTEL LTMTDMMSED EGKTETTNIN SVIIETDIIG SDLLKNSDPE TQSSMPDVPY EPDLDIEIDF PRAAEELDME NEFLLPPVFG EEYEEQPRPR SKKKGAKRKA VSGYQSHDDS SDNSECSFPF KYTYGVNAWK HWVKTRQLDE DLLVLDELKS SKSVKLKEDL LSHTTAELNY GLAHFVNEIR RPNGENYAPD SIYYLCLGIQ EYLCGSNRKD NIFIDPGYQT FEQELNKILR SWQPSILPDG SIFSRVEEDY LWRIKQLGSH SPVALLNTLF YFNTKYFGLK TVEQHLRLSF GTVFRHW