Details for: PRDM2

Gene ID: 7799

Symbol: PRDM2

Ensembl ID: ENSG00000116731

Description: PR/SET domain 2

Associated with

  • Chromatin remodeling
    (GO:0006338)
  • Determination of adult lifespan
    (GO:0008340)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Golgi apparatus
    (GO:0005794)
  • Histone h3k9 trimethyltransferase activity
    (GO:0140949)
  • Methylation
    (GO:0032259)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Zinc ion binding
    (GO:0008270)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 421.0994
    Cell Significance Index: -65.5000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 254.9248
    Cell Significance Index: -64.6600
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 144.7929
    Cell Significance Index: -68.3600
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 134.1638
    Cell Significance Index: -54.5100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 125.1591
    Cell Significance Index: -64.3800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 57.1410
    Cell Significance Index: -54.5600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 54.5437
    Cell Significance Index: -67.2500
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 23.0938
    Cell Significance Index: -61.8700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.8450
    Cell Significance Index: -54.8100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 17.1235
    Cell Significance Index: -67.5700
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 14.3746
    Cell Significance Index: -31.4600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.3922
    Cell Significance Index: 479.8800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.2149
    Cell Significance Index: 30.2200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.9490
    Cell Significance Index: 125.7400
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 1.9035
    Cell Significance Index: 131.6400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.9001
    Cell Significance Index: 53.1000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.7487
    Cell Significance Index: 44.9500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.3225
    Cell Significance Index: 101.4900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.2986
    Cell Significance Index: 465.8000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.2267
    Cell Significance Index: 150.8300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.1828
    Cell Significance Index: 66.3700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1816
    Cell Significance Index: 213.0100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.1390
    Cell Significance Index: 22.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.8917
    Cell Significance Index: 54.8100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.8745
    Cell Significance Index: 604.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.8299
    Cell Significance Index: 36.7100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8013
    Cell Significance Index: 87.1600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.7418
    Cell Significance Index: 28.0900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7006
    Cell Significance Index: 139.0400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.6874
    Cell Significance Index: 94.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6778
    Cell Significance Index: 35.2100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6516
    Cell Significance Index: 39.1200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5167
    Cell Significance Index: 466.5700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4423
    Cell Significance Index: 43.7500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4369
    Cell Significance Index: 193.1900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.4146
    Cell Significance Index: 11.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.4134
    Cell Significance Index: 778.4700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4053
    Cell Significance Index: 221.3400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 0.3902
    Cell Significance Index: 20.3300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.3709
    Cell Significance Index: 43.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3361
    Cell Significance Index: 9.6900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.3356
    Cell Significance Index: 9.6200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2996
    Cell Significance Index: 6.4900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2743
    Cell Significance Index: 44.6200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2192
    Cell Significance Index: 9.9400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1896
    Cell Significance Index: 8.8400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1650
    Cell Significance Index: 7.7600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1190
    Cell Significance Index: 22.6400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1084
    Cell Significance Index: 2.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1014
    Cell Significance Index: 46.0100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0904
    Cell Significance Index: 1.5500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0819
    Cell Significance Index: 52.0500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0585
    Cell Significance Index: 0.7200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0469
    Cell Significance Index: 6.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0283
    Cell Significance Index: 43.5400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0277
    Cell Significance Index: 51.1000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0216
    Cell Significance Index: 29.3100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0213
    Cell Significance Index: 0.7500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0060
    Cell Significance Index: 0.1600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0048
    Cell Significance Index: 0.3200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0204
    Cell Significance Index: -3.4800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0246
    Cell Significance Index: -15.3600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0277
    Cell Significance Index: -20.5300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0390
    Cell Significance Index: -4.4500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0398
    Cell Significance Index: -5.7800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0400
    Cell Significance Index: -2.8300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0543
    Cell Significance Index: -39.8000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0783
    Cell Significance Index: -59.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0842
    Cell Significance Index: -47.4900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1503
    Cell Significance Index: -7.8900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1541
    Cell Significance Index: -17.6500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1781
    Cell Significance Index: -37.5100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1889
    Cell Significance Index: -24.4100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2008
    Cell Significance Index: -57.7900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2071
    Cell Significance Index: -13.0500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.2141
    Cell Significance Index: -24.9600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2205
    Cell Significance Index: -16.4400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.3064
    Cell Significance Index: -31.3000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.3426
    Cell Significance Index: -3.1600
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.4131
    Cell Significance Index: -10.0800
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.4436
    Cell Significance Index: -6.3700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5177
    Cell Significance Index: -53.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5929
    Cell Significance Index: -12.3000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.7177
    Cell Significance Index: -20.4800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7278
    Cell Significance Index: -57.6400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.7752
    Cell Significance Index: -24.8300
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.8503
    Cell Significance Index: -18.1800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.8638
    Cell Significance Index: -18.9200
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.8965
    Cell Significance Index: -23.9800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.9343
    Cell Significance Index: -5.6500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.9772
    Cell Significance Index: -20.7400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.9841
    Cell Significance Index: -60.3400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -1.0071
    Cell Significance Index: -12.0100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -1.0089
    Cell Significance Index: -16.8900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.0205
    Cell Significance Index: -33.4100
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -1.0282
    Cell Significance Index: -15.1800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.0354
    Cell Significance Index: -32.9800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.1903
    Cell Significance Index: -31.3000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.2259
    Cell Significance Index: -24.2400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.2570
    Cell Significance Index: -43.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PRDM2 is a member of the PR domain zinc finger protein family, characterized by its unique PR domain, which is essential for its transcriptional regulatory activity. The protein is highly conserved across species, suggesting its importance in fundamental biological processes. PRDM2 is primarily expressed in cells of the nervous system, immune cells, and epithelial tissues, underscoring its role in maintaining tissue homeostasis and immune function. **Pathways and Functions:** PRDM2 is involved in multiple signaling pathways, including: 1. **Chromatin remodeling**: PRDM2 interacts with histone-modifying enzymes to regulate chromatin structure and gene expression. 2. **RNA polymerase II-specific transcription**: PRDM2 acts as a transcriptional activator or repressor, modulating the expression of genes involved in various cellular processes. 3. **Histone H3K9 trimethyltransferase activity**: PRDM2 is a histone methyltransferase that marks histone H3K9, influencing chromatin structure and gene expression. 4. **Golgi apparatus regulation**: PRDM2 is involved in regulating the Golgi apparatus, which is essential for protein modification, sorting, and trafficking. PRDM2's functions include: 1. **Gene regulation**: PRDM2 modulates the expression of genes involved in cell differentiation, survival, and immune response. 2. **Immune function**: PRDM2 is expressed in immune cells, where it regulates the expression of genes involved in immune cell development, function, and homeostasis. 3. **Cell differentiation**: PRDM2 is involved in regulating the differentiation of neural progenitor cells and other cell types. **Clinical Significance:** PRDM2's involvement in immune function and gene regulation makes it a potential target for the treatment of various diseases, including: 1. **Autoimmune disorders**: PRDM2's role in regulating immune cell function and gene expression makes it a potential target for the treatment of autoimmune disorders, such as multiple sclerosis and rheumatoid arthritis. 2. **Cancer**: PRDM2's involvement in chromatin remodeling and gene regulation suggests its potential role in cancer development and progression. 3. **Neurodegenerative diseases**: PRDM2's expression in neural cells and its involvement in gene regulation make it a potential target for the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's. In conclusion, PRDM2 is a complex transcriptional regulator that plays a crucial role in various cellular processes, including gene expression, chromatin remodeling, and immune function. Further research is needed to fully elucidate PRDM2's functions and its potential as a therapeutic target for various diseases.

Genular Protein ID: 1162951212

Symbol: PRDM2_HUMAN

Name: PR domain zinc finger protein 2

UniProtKB Accession Codes:

Q13029 B1AJZ4 B5MC68 Q13149 Q14550 Q5THJ1 Q5VUL9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 5 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 EC 2 EMBL 8 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PIRSF 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 5 Pumba 1 RNAct 1 RefSeq 12 Rhea 3 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7538672

Title: The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein.

PubMed ID: 7538672

DOI: 10.1073/pnas.92.10.4467

PubMed ID: 9006946

Title: The retinoblastoma interacting zinc finger gene RIZ produces a PR domain-lacking product through an internal promoter.

PubMed ID: 9006946

DOI: 10.1074/jbc.272.5.2984

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7590293

Title: Identification and cloning of the G3B cDNA encoding a 3' segment of a protein binding to GATA-3.

PubMed ID: 7590293

DOI: 10.1016/0378-1119(95)00420-b

PubMed ID: 8654390

Title: cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene.

PubMed ID: 8654390

DOI: 10.1111/j.1432-1033.1996.00471.x

PubMed ID: 14633678

Title: Inactivation of a histone methyltransferase by mutations in human cancers.

PubMed ID: 14633678

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25755297

Title: System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.

PubMed ID: 25755297

DOI: 10.1074/mcp.o114.044792

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 18082620

Title: Structural studies of the SET domain from RIZ1 tumor suppressor.

PubMed ID: 18082620

DOI: 10.1016/j.bbrc.2007.12.034

PubMed ID: 20084102

Title: Structural biology of human H3K9 methyltransferases.

PubMed ID: 20084102

DOI: 10.1371/journal.pone.0008570

Sequence Information:

  • Length: 1718
  • Mass: 188915
  • Checksum: 536BD68667AFE433
  • Sequence:
    • MNQNTTEPVA ATETLAEVPE HVLRGLPEEV RLFPSAVDKT RIGVWATKPI LKGKKFGPFV 
GDKKKRSQVK NNVYMWEVYY PNLGWMCIDA TDPEKGNWLR YVNWACSGEE QNLFPLEINR 
AIYYKTLKPI APGEELLVWY NGEDNPEIAA AIEEERASAR SKRSSPKSRK GKKKSQENKN 
KGNKIQDIQL KTSEPDFTSA NMRDSAEGPK EDEEKPSASA LEQPATLQEV ASQEVPPELA 
TPAPAWEPQP EPDERLEAAA CEVNDLGEEE EEEEEEDEEE EEDDDDDELE DEGEEEASMP 
NENSVKEPEI RCDEKPEDLL EEPKTTSEET LEDCSEVTPA MQIPRTKEEA NGDVFETFMF 
PCQHCERKFT TKQGLERHMH IHISTVNHAF KCKYCGKAFG TQINRRRHER RHEAGLKRKP 
SQTLQPSEDL ADGKASGENV ASKDDSSPPS LGPDCLIMNS EKASQDTINS SVVEENGEVK 
ELHPCKYCKK VFGTHTNMRR HQRRVHERHL IPKGVRRKGG LEEPQPPAEQ AQATQNVYVP 
STEPEEEGEA DDVYIMDISS NISENLNYYI DGKIQTNNNT SNCDVIEMES ASADLYGINC 
LLTPVTVEIT QNIKTTQVPV TEDLPKEPLG STNSEAKKRR TASPPALPKI KAETDSDPMV 
PSCSLSLPLS ISTTEAVSFH KEKSVYLSSK LKQLLQTQDK LTPAGISATE IAKLGPVCVS 
APASMLPVTS SRFKRRTSSP PSSPQHSPAL RDFGKPSDGK AAWTDAGLTS KKSKLESHSD 
SPAWSLSGRD ERETVSPPCF DEYKMSKEWT ASSAFSSVCN QQPLDLSSGV KQKAEGTGKT 
PVQWESVLDL SVHKKHCSDS EGKEFKESHS VQPTCSAVKK RKPTTCMLQK VLLNEYNGID 
LPVENPADGT RSPSPCKSLE AQPDPDLGPG SGFPAPTVES TPDVCPSSPA LQTPSLSSGQ 
LPPLLIPTDP SSPPPCPPVL TVATPPPPLL PTVPLPAPSS SASPHPCPSP LSNATAQSPL 
PILSPTVSPS PSPIPPVEPL MSAASPGPPT LSSSSSSSSS SSSFSSSSSS SSPSPPPLSA 
ISSVVSSGDN LEASLPMISF KQEELENEGL KPREEPQSAA EQDVVVQETF NKNFVCNVCE 
SPFLSIKDLT KHLSIHAEEW PFKCEFCVQL FKDKTDLSEH RFLLHGVGNI FVCSVCKKEF 
AFLCNLQQHQ RDLHPDKVCT HHEFESGTLR PQNFTDPSKA HVEHMQSLPE DPLETSKEEE 
ELNDSSEELY TTIKIMASGI KTKDPDVRLG LNQHYPSFKP PPFQYHHRNP MGIGVTATNF 
TTHNIPQTFT TAIRCTKCGK GVDNMPELHK HILACASASD KKRYTPKKNP VPLKQTVQPK 
NGVVVLDNSG KNAFRRMGQP KRLNFSVELS KMSSNKLKLN ALKKKNQLVQ KAILQKNKSA 
KQKADLKNAC ESSSHICPYC NREFTYIGSL NKHAAFSCPK KPLSPPKKKV SHSSKKGGHS 
SPASSDKNSN SNHRRRTADA EIKMQSMQTP LGKTRARSSG PTQVPLPSSS FRSKQNVKFA 
ASVKSKKPSS SSLRNSSPIR MAKITHVEGK KPKAVAKNHS AQLSSKTSRS LHVRVQKSKA 
VLQSKSTLAS KKRTDRFNIK SRERSGGPVT RSLQLAAAAD LSENKREDGS AKQELKDFSY 
SLRLASRCSP PAAPYITRQY RKVKAPAAAQ FQGPFFKE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.