Details for: PDHX

Gene ID: 8050

Symbol: PDHX

Ensembl ID: ENSG00000110435

Description: pyruvate dehydrogenase complex component X

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 213.8928
    Cell Significance Index: -33.2700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 131.4050
    Cell Significance Index: -33.3300
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 71.7716
    Cell Significance Index: -33.8900
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 70.2757
    Cell Significance Index: -28.5500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 62.7351
    Cell Significance Index: -32.2700
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 29.9767
    Cell Significance Index: -28.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 28.7602
    Cell Significance Index: -35.4600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 11.7326
    Cell Significance Index: -31.4300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.6306
    Cell Significance Index: -29.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 9.1522
    Cell Significance Index: -36.1200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 5.4784
    Cell Significance Index: -11.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.9474
    Cell Significance Index: 390.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.5638
    Cell Significance Index: 310.3400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.5480
    Cell Significance Index: 21.1200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.4320
    Cell Significance Index: 513.6500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.2578
    Cell Significance Index: 96.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.2164
    Cell Significance Index: 81.7900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.2120
    Cell Significance Index: 68.0100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 1.1099
    Cell Significance Index: 28.5300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 1.0405
    Cell Significance Index: 39.4000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.0247
    Cell Significance Index: 27.3600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.0219
    Cell Significance Index: 45.2000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.8817
    Cell Significance Index: 25.1600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8466
    Cell Significance Index: 22.6900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.7825
    Cell Significance Index: 9.7100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.6837
    Cell Significance Index: 17.0900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5821
    Cell Significance Index: 35.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5745
    Cell Significance Index: 39.7300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4662
    Cell Significance Index: 420.9300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4637
    Cell Significance Index: 12.9600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.4406
    Cell Significance Index: 27.7700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.4120
    Cell Significance Index: 9.8800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.3653
    Cell Significance Index: 16.5600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.3319
    Cell Significance Index: 7.1900
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.3271
    Cell Significance Index: 7.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3196
    Cell Significance Index: 57.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2986
    Cell Significance Index: 36.7200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.2811
    Cell Significance Index: 4.1500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2271
    Cell Significance Index: 124.0300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1969
    Cell Significance Index: 9.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1890
    Cell Significance Index: 355.7900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1855
    Cell Significance Index: 117.8200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1789
    Cell Significance Index: 34.0500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.1719
    Cell Significance Index: 27.9700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1501
    Cell Significance Index: 68.1200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1400
    Cell Significance Index: 7.3500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1241
    Cell Significance Index: 12.2800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1136
    Cell Significance Index: 50.2100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.1130
    Cell Significance Index: 5.8700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1039
    Cell Significance Index: 3.6500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0897
    Cell Significance Index: 165.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0895
    Cell Significance Index: 137.7800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0807
    Cell Significance Index: 11.0800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0775
    Cell Significance Index: 1.6500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0437
    Cell Significance Index: 1.1900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0318
    Cell Significance Index: 43.1800
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0309
    Cell Significance Index: 0.5300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.0284
    Cell Significance Index: 3.6700
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.0192
    Cell Significance Index: 0.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0149
    Cell Significance Index: 1.1100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0112
    Cell Significance Index: 1.3200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0021
    Cell Significance Index: 0.3600
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0106
    Cell Significance Index: -7.7700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0247
    Cell Significance Index: -18.6600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0253
    Cell Significance Index: -18.7600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0485
    Cell Significance Index: -2.2800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0502
    Cell Significance Index: -28.3300
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.0594
    Cell Significance Index: -0.7500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0594
    Cell Significance Index: -37.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0623
    Cell Significance Index: -7.9900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0681
    Cell Significance Index: -1.3300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0859
    Cell Significance Index: -8.7800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0954
    Cell Significance Index: -2.0900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.1018
    Cell Significance Index: -0.8300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1022
    Cell Significance Index: -1.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1036
    Cell Significance Index: -29.8000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1058
    Cell Significance Index: -15.3800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1146
    Cell Significance Index: -3.6700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1221
    Cell Significance Index: -6.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1391
    Cell Significance Index: -14.4800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1469
    Cell Significance Index: -9.4800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1691
    Cell Significance Index: -19.7100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1696
    Cell Significance Index: -35.7300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1911
    Cell Significance Index: -21.9000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2157
    Cell Significance Index: -4.6100
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.2282
    Cell Significance Index: -16.1400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2903
    Cell Significance Index: -4.8900
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: -0.3009
    Cell Significance Index: -1.3100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3159
    Cell Significance Index: -25.0200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3388
    Cell Significance Index: -7.1900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3629
    Cell Significance Index: -10.6900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3881
    Cell Significance Index: -4.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3908
    Cell Significance Index: -13.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3956
    Cell Significance Index: -24.2600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4732
    Cell Significance Index: -15.0700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4734
    Cell Significance Index: -9.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.4991
    Cell Significance Index: -16.3400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5161
    Cell Significance Index: -13.5700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.5245
    Cell Significance Index: -4.8300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.5311
    Cell Significance Index: -7.5600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The PDHX gene is a mitochondrial gene, which means that it is encoded by DNA within the mitochondria, rather than the nucleus. This is in contrast to nuclear-encoded genes, which are located in the cell's nucleus. The PDHX gene has been shown to be significantly expressed in specific cell types, including germ cells, ciliary muscle cells, and various types of neurons, particularly those involved in the regulation of neurotransmitter release. The protein encoded by the PDHX gene is also known as pyruvate dehydrogenase protein X component, mitochondrial (ODPX_HUMAN). **Pathways and Functions** The PDHX gene is involved in several key metabolic pathways, including: 1. **Acetyl-CoA biosynthetic process from pyruvate**: The PDHX gene plays a critical role in the conversion of pyruvate into acetyl-CoA, a molecule that can be fed into the citric acid cycle to produce energy. 2. **Glyoxylate metabolism and glycine degradation**: The PDHX gene is also involved in the metabolism of glyoxylate, a molecule that is produced during the breakdown of certain amino acids. 3. **Metabolism of amino acids and derivatives**: The PDHX gene is involved in the regulation of amino acid metabolism, including the breakdown and synthesis of certain amino acids. 4. **Mitochondrial pyruvate dehydrogenase complex**: The PDHX gene is specifically localized to the mitochondrial matrix, where it is involved in the regulation of the PDC activity. **Clinical Significance** Mutations or alterations in the expression of the PDHX gene have been associated with various neurological disorders, including: 1. **Neurodegenerative diseases**: Mutations in the PDHX gene have been linked to neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. 2. **Neurodevelopmental disorders**: The PDHX gene has also been implicated in neurodevelopmental disorders, such as epilepsy and autism spectrum disorder. 3. **Mitochondrial disorders**: The PDHX gene is involved in mitochondrial function, and mutations in the gene have been associated with mitochondrial disorders, such as mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS). In summary, the PDHX gene plays a critical role in the regulation of the pyruvate dehydrogenase complex, a key enzyme complex involved in the metabolism of pyruvate. Mutations or alterations in the expression of the PDHX gene have been associated with various neurological disorders, highlighting its importance in brain development and function.

Genular Protein ID: 3740217736

Symbol: ODPX_HUMAN

Name: Pyruvate dehydrogenase protein X component, mitochondrial

UniProtKB Accession Codes:

O00330 B4DW62 D3DR11 E9PB14 E9PBP7 O60221 Q96FV8 Q99783

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChiTaRS 1 ComplexPortal 2 DIP 1 DNASU 1 DisGeNET 1 EMBL 12 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 5 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 3 RefSeq 3 SIGNOR 1 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9242632

Title: Dihydrolipoamide dehydrogenase-binding protein of the human pyruvate dehydrogenase complex. DNA-derived amino acid sequence, expression, and reconstitution of the pyruvate dehydrogenase complex.

PubMed ID: 9242632

DOI: 10.1074/jbc.272.32.19746

PubMed ID: 9399911

Title: Mutations in PDX1, the human lipoyl-containing component X of the pyruvate dehydrogenase-complex gene on chromosome 11p1, in congenital lactic acidosis.

PubMed ID: 9399911

DOI: 10.1086/301653

PubMed ID: 9467010

Title: Detection of a homozygous four base pair deletion in the protein X gene in a case of pyruvate dehydrogenase complex deficiency.

PubMed ID: 9467010

DOI: 10.1093/hmg/7.3.501

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9110174

Title: Large-scale concatenation cDNA sequencing.

PubMed ID: 9110174

DOI: 10.1101/gr.7.4.353

PubMed ID: 14638692

Title: Organization of the cores of the mammalian pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and their capacities to bind the E1 and E3 components.

PubMed ID: 14638692

DOI: 10.1074/jbc.m308172200

PubMed ID: 20160912

Title: Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex.

PubMed ID: 20160912

DOI: 10.1016/j.molcatb.2009.05.001

PubMed ID: 19608861

Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.

PubMed ID: 19608861

DOI: 10.1126/science.1175371

PubMed ID: 20385101

Title: Characterization of interactions of dihydrolipoamide dehydrogenase with its binding protein in the human pyruvate dehydrogenase complex.

PubMed ID: 20385101

DOI: 10.1016/j.bbrc.2010.04.038

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25525879

Title: Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity.

PubMed ID: 25525879

DOI: 10.1016/j.cell.2014.11.046

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 16263718

Title: How dihydrolipoamide dehydrogenase-binding protein binds dihydrolipoamide dehydrogenase in the human pyruvate dehydrogenase complex.

PubMed ID: 16263718

DOI: 10.1074/jbc.m507850200

PubMed ID: 16442803

Title: Structural insight into interactions between dihydrolipoamide dehydrogenase (E3) and E3 binding protein of human pyruvate dehydrogenase complex.

PubMed ID: 16442803

DOI: 10.1016/j.str.2006.01.001

PubMed ID: 20361979

Title: Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly.

PubMed ID: 20361979

DOI: 10.1016/j.jmb.2010.03.043

Sequence Information:

  • Length: 501
  • Mass: 54122
  • Checksum: 9CF0C1DAE9E12EF9
  • Sequence:
    • MAASWRLGCD PRLLRYLVGF PGRRSVGLVK GALGWSVSRG ANWRWFHSTQ WLRGDPIKIL 
MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK 
NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL 
RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT 
PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH 
AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF 
IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL 
GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD 
ELATRFLKSF KANLENPIRL A

Genular Protein ID: 2723545161

Symbol: A0A8C8MSB2_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A8C8MSB2

Database IDs:

ARBA 4 CDD 1 CTD 1 ChEBI 1 DisGeNET 1 EMBL 4 Ensembl 2 GO 4 Gene3D 3 GeneTree 1 HGNC 1 InterPro 8 NCBI Taxonomy 1 PANTHER 2 PROSITE 5 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 441
  • Mass: 47287
  • Checksum: 7D8BF29B2ED17CDA
  • Sequence:
    • MPSLSPTMEE GNIVKWLKKE GEAVSAGDAL CEIETDKAVV TLDASDDGIL AKIVVEEGSK 
NIRLGSLIGL IVEEGEDWKH VEIPKDVGPP PPVSKPSEPR PSPEPQISIP VKKEHIPGTL 
RFRLSPAARN ILEKHSLDAS QGTATGPRGI FTKEDALKLV QLKQTGKITE SRPTPAPTAT 
PTAPSPLQAT AGPSYPRPVI PPVSTPGQPN AVGTFTEIPA SNIRRVIAKR LTESKSTVPH 
AYATADCDLG AVLKVRQDLV KDDIKVSVND FIIKAAAVTL KQMPDVNVSW DGEGPKQLPF 
IDISVAVATD KGLLTPIIKD AAAKGIQEIA DSVKALSKKA RDGKLLPEEY QGGSFSISNL 
GMFGIDEFTA VINPPQACIL AVGRFRPVLK LTEDEEGNAK LQQRQLITVT MSSDSRVVDD 
ELATRFLKSF KANLENPIRL A

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.