Details for: IFT88
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 245.4592
Cell Significance Index: -38.1800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 150.8811
Cell Significance Index: -38.2700 - Cell Name: embryonic stem cell (CL0002322)
Fold Change: 91.2252
Cell Significance Index: -37.5800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 84.4272
Cell Significance Index: -39.8600 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 79.6540
Cell Significance Index: -32.3600 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 33.8416
Cell Significance Index: -32.3100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 32.2153
Cell Significance Index: -39.7200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 14.1403
Cell Significance Index: -37.8800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 10.1272
Cell Significance Index: -39.9600 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 8.6723
Cell Significance Index: -18.9800 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 3.9277
Cell Significance Index: 46.8200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.0329
Cell Significance Index: 128.1300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 1.5969
Cell Significance Index: 316.9200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.4066
Cell Significance Index: 282.1600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.2245
Cell Significance Index: 1105.6200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.2092
Cell Significance Index: 53.4900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 1.1387
Cell Significance Index: 43.1200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.9764
Cell Significance Index: 54.7900 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.9707
Cell Significance Index: 348.1600 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.8356
Cell Significance Index: 90.8900 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.7708
Cell Significance Index: 125.3600 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.7457
Cell Significance Index: 44.7700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7124
Cell Significance Index: 492.6900 - Cell Name: preadipocyte (CL0002334)
Fold Change: 0.7014
Cell Significance Index: 13.6900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.6182
Cell Significance Index: 61.1500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.6049
Cell Significance Index: 330.3400 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.5935
Cell Significance Index: 36.4800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.5485
Cell Significance Index: 13.7100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.5396
Cell Significance Index: 11.6900 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4899
Cell Significance Index: 22.2100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.4381
Cell Significance Index: 7.3800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.4070
Cell Significance Index: 55.8900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3978
Cell Significance Index: 27.5100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.3539
Cell Significance Index: 27.1600 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.3359
Cell Significance Index: 632.3700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.3174
Cell Significance Index: 8.8700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.2793
Cell Significance Index: 5.9700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2569
Cell Significance Index: 6.1600 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2532
Cell Significance Index: 45.6500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2122
Cell Significance Index: 391.4000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.2037
Cell Significance Index: 313.6000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1713
Cell Significance Index: 11.5200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1708
Cell Significance Index: 108.4800 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1530
Cell Significance Index: 67.6400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1318
Cell Significance Index: 179.2300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.1126
Cell Significance Index: 14.4300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1082
Cell Significance Index: 20.5900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0868
Cell Significance Index: 3.0500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0800
Cell Significance Index: 9.8400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0754
Cell Significance Index: 34.2200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0175
Cell Significance Index: 0.3000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0004
Cell Significance Index: -0.0100 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0040
Cell Significance Index: -2.9500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0122
Cell Significance Index: -1.7800 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0400
Cell Significance Index: -29.6400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0452
Cell Significance Index: -34.2300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0641
Cell Significance Index: -36.1700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0719
Cell Significance Index: -44.9100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.1011
Cell Significance Index: -2.6000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1202
Cell Significance Index: -34.5900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1242
Cell Significance Index: -21.2000 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1359
Cell Significance Index: -15.8400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1713
Cell Significance Index: -17.5000 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1822
Cell Significance Index: -21.4900 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1822
Cell Significance Index: -3.8800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.1960
Cell Significance Index: -10.2100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2022
Cell Significance Index: -21.0600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.2038
Cell Significance Index: -42.9200 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2068
Cell Significance Index: -9.7200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.2144
Cell Significance Index: -27.7000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2209
Cell Significance Index: -10.3000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2242
Cell Significance Index: -16.7100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.2299
Cell Significance Index: -6.6300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2350
Cell Significance Index: -15.1600 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2428
Cell Significance Index: -27.8200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2555
Cell Significance Index: -18.0700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.2694
Cell Significance Index: -8.6300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.2764
Cell Significance Index: -4.0800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2970
Cell Significance Index: -15.4300 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.3520
Cell Significance Index: -5.0600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.3580
Cell Significance Index: -9.5600 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.3785
Cell Significance Index: -10.8000 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.3797
Cell Significance Index: -4.7100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.3812
Cell Significance Index: -30.2000 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.3924
Cell Significance Index: -6.5700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4556
Cell Significance Index: -23.9200 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: -0.4741
Cell Significance Index: -4.0300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.4891
Cell Significance Index: -10.3800 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.4910
Cell Significance Index: -13.3700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.5345
Cell Significance Index: -32.7700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.5891
Cell Significance Index: -12.9000 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.5922
Cell Significance Index: -20.5800 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.6191
Cell Significance Index: -7.7200 - Cell Name: peg cell (CL4033014)
Fold Change: -0.6272
Cell Significance Index: -14.4900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6634
Cell Significance Index: -21.1300 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.6858
Cell Significance Index: -13.5600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6979
Cell Significance Index: -18.3500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6988
Cell Significance Index: -22.8800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.7187
Cell Significance Index: -10.6100 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.7212
Cell Significance Index: -14.4800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1160417290
Symbol: IFT88_HUMAN
Name: Intraflagellar transport protein 88 homolog
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7633404
Title: Characterization of the human homologue of the mouse Tg737 candidate polycystic kidney disease gene.
PubMed ID: 7633404
DOI: 10.1093/hmg/4.4.559
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17604723
Title: HEF1-dependent Aurora A activation induces disassembly of the primary cilium.
PubMed ID: 17604723
PubMed ID: 28625565
Title: The CEP19-RABL2 GTPase complex binds IFT-B to initiate intraflagellar transport at the ciliary base.
PubMed ID: 28625565
PubMed ID: 28428259
Title: RABL2 interacts with the intraflagellar transport-B complex and CEP19 and participates in ciliary assembly.
PubMed ID: 28428259
PubMed ID: 27767179
Title: The serologically defined colon cancer antigen-3 (SDCCAG3) is involved in the regulation of ciliogenesis.
PubMed ID: 27767179
DOI: 10.1038/srep35399
PubMed ID: 30388400
Title: Biallelic mutations in LRRC56, encoding a protein associated with intraflagellar transport, cause mucociliary clearance and laterality defects.
PubMed ID: 30388400
Sequence Information:
- Length: 824
- Mass: 93192
- Checksum: 12E30169CFC5476B
- Sequence:
MMQNVHLAPE TDEDDLYSGY NDYNPIYDIE ELENDAAFQQ AVRTSHGRRP PITAKISSTA VTRPIATGYG SKTSLASSIG RPMTGAIQDG VTRPMTAVRA AGFTKAALRG SAFDPLSQSR GPASPLEAKK KDSPEEKIKQ LEKEVNELVE ESCIANSCGD LKLALEKAKD AGRKERVLVR QREQVTTPEN INLDLTYSVL FNLASQYSVN EMYAEALNTY QVIVKNKMFS NAGILKMNMG NIYLKQRNYS KAIKFYRMAL DQVPSVNKQM RIKIMQNIGV TFIQAGQYSD AINSYEHIMS MAPNLKAGYN LTICYFAIGD REKMKKAFQK LITVPLEIDE DKYISPSDDP HTNLVTEAIK NDHLRQMERE RKAMAEKYIM TSAKLIAPVI ETSFAAGYDW CVEVVKASQY VELANDLEIN KAVTYLRQKD YNQAVEILKV LEKKDSRVKS AAATNLSALY YMGKDFAQAS SYADIAVNSD RYNPAALTNK GNTVFANGDY EKAAEFYKEA LRNDSSCTEA LYNIGLTYEK LNRLDEALDC FLKLHAILRN SAEVLYQIAN IYELMENPSQ AIEWLMQVVS VIPTDPQVLS KLGELYDREG DKSQAFQYYY ESYRYFPCNI EVIEWLGAYY IDTQFWEKAI QYFERASLIQ PTQVKWQLMV ASCFRRSGNY QKALDTYKDT HRKFPENVEC LRFLVRLCTD LGLKDAQEYA RKLKRLEKMK EIREQRIKSG RDGSGGSRGK REGSASGDSG QNYSASSKGE RLSARLRALP GTNEPYESSS NKEIDASYVD PLGPQIERPK TAAKKRIDED DFADEELGDD LLPE
Genular Protein ID: 810550981
Symbol: B3KX42_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 795
- Mass: 90800
- Checksum: 341FE49A2472A610
- Sequence:
MKFTNTKVQM MQNVHLAPET DEDDLYSGYN DYNPIYDIEE LENDAAFQQA VRTSHGRRPP ITAKISSTAV TRPIATGYGS KTSLASSIGR PMTGAIQDGV TRPMTAVRAA GFTKAALRGS AFDPLSQSRG PASPLEAKKK DSPEEKIKQL EKEVNELVEE SCIANSCGDL KLALEKAKDA GRKERVLVRQ REQVTTPENI NLDLTYSVLF NLASQYSVNE MYAEALNTYQ VIVKNKMFSN AGILKMNMGN IYLKQRNYSK AIKFYRMALD QVPSVNKQMR IKIMQNIGVT FIQAGQYSDA INSYEHIMSM APNLKAGYNL TICYFAIGDR EKMKKAFQKL ITVPLEIDED KYISPSDDPH TNLVTEAIKN DHLRQMERER KAMAEKYIMT SAKLIAPVIE TSFAAGYDWC VEVVKASQYV ELANDLEINK AVTYLRQKDY NQAVEFLKVL EKKDNRVKSA AATNLSALYY MGKDFAQASS YADIAVNSDR YNLAALTNKG NTVFANGDYE KAAEFYKEAL RNDSSCTEAL YNIGLTYEKL NRLDEALDCF LKLHAILRNS AEVLYQIANI YELMENPSQA IEWLMQVVSV IPTDPQVLSK LGELYDREGD KSQAFQYYYE SYRYFPCNIE VIEWLGAYYI DTQFWEKAIQ YFERASLIQP TQVKWQLMVA SCFRRSGNYQ KALDTYKDTH RKFPENVECS GSVRTGHMER DPLNLLPRKS VLPGPEIAKR NYFSGEKYYL SAFLSSSLHR SWIKRCSRIC QKTEEVGKNE RNKGTAHKVR QRWQWGLPWQ KRRKC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.