Details for: NRIP1

Gene ID: 8204

Symbol: NRIP1

Ensembl ID: ENSG00000180530

Description: nuclear receptor interacting protein 1

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: granule cell (CL0000120)
    Fold Change: 4.11
    Marker Score: 30990
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 3.99
    Marker Score: 20931
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 3.78
    Marker Score: 67078
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 3.57
    Marker Score: 8206
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 3.08
    Marker Score: 16571
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: 2.86
    Marker Score: 1420
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 2.78
    Marker Score: 2112
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 2.57
    Marker Score: 2219
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 2.47
    Marker Score: 2639
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.42
    Marker Score: 1824
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.29
    Marker Score: 2634
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.09
    Marker Score: 41623
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 2.08
    Marker Score: 6962
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.89
    Marker Score: 7694
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: 1.86
    Marker Score: 4566
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.86
    Marker Score: 63126
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 1.84
    Marker Score: 1507
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 1.8
    Marker Score: 18226
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.8
    Marker Score: 1385
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.79
    Marker Score: 110287
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.79
    Marker Score: 66102
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: 1.79
    Marker Score: 1217.5
  • Cell Name: fat cell (CL0000136)
    Fold Change: 1.79
    Marker Score: 998
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.77
    Marker Score: 15170
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.76
    Marker Score: 16679
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 1.75
    Marker Score: 26218
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 1.75
    Marker Score: 6483
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: 1.74
    Marker Score: 1484
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: 1.74
    Marker Score: 1391
  • Cell Name: CD34-positive, CD38-negative hematopoietic stem cell (CL0001024)
    Fold Change: 1.73
    Marker Score: 1252
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.7
    Marker Score: 1794
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 1.66
    Marker Score: 15618
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.66
    Marker Score: 35434
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 1.64
    Marker Score: 6826.5
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 1.61
    Marker Score: 6686
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.6
    Marker Score: 957
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.59
    Marker Score: 587
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.54
    Marker Score: 11792
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.51
    Marker Score: 442
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 1.5
    Marker Score: 56958
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 1.49
    Marker Score: 429.5
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.48
    Marker Score: 2477
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 1.47
    Marker Score: 565
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.47
    Marker Score: 2820
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 1.46
    Marker Score: 8650
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.45
    Marker Score: 5154
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 1.45
    Marker Score: 431
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.44
    Marker Score: 2549
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 1.44
    Marker Score: 5559
  • Cell Name: megakaryocyte progenitor cell (CL0000553)
    Fold Change: 1.44
    Marker Score: 401
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.43
    Marker Score: 803
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 1.43
    Marker Score: 4683
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.42
    Marker Score: 2187
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 1.4
    Marker Score: 684
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.39
    Marker Score: 3281
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 1.39
    Marker Score: 667
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.37
    Marker Score: 2011
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 1.35
    Marker Score: 697
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 1.34
    Marker Score: 1449
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.34
    Marker Score: 487
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.32
    Marker Score: 45723
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 1.31
    Marker Score: 3134
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 1.31
    Marker Score: 1409
  • Cell Name: epicardial adipocyte (CL1000309)
    Fold Change: 1.3
    Marker Score: 632
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 1.3
    Marker Score: 5430
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 1.29
    Marker Score: 542
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.29
    Marker Score: 3153.5
  • Cell Name: hematopoietic precursor cell (CL0008001)
    Fold Change: 1.29
    Marker Score: 452
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.26
    Marker Score: 12716
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 1.26
    Marker Score: 14143
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.24
    Marker Score: 976
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.23
    Marker Score: 283
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.22
    Marker Score: 3263
  • Cell Name: germ cell (CL0000586)
    Fold Change: 1.21
    Marker Score: 2109.5
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.2
    Marker Score: 316.5
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.2
    Marker Score: 18794
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.19
    Marker Score: 691
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: 1.16
    Marker Score: 406
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.16
    Marker Score: 396
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.16
    Marker Score: 318
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.16
    Marker Score: 1156
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 1.15
    Marker Score: 422
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 1.15
    Marker Score: 809
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.15
    Marker Score: 1417
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.14
    Marker Score: 362
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.14
    Marker Score: 629
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.14
    Marker Score: 684
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.13
    Marker Score: 11715
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.11
    Marker Score: 2030
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 1.11
    Marker Score: 359
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 1.11
    Marker Score: 635
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.11
    Marker Score: 615
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.1
    Marker Score: 7104
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.1
    Marker Score: 579
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 1.1
    Marker Score: 28136
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 1.09
    Marker Score: 1088
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.08
    Marker Score: 1197
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.08
    Marker Score: 535
  • Cell Name: late pro-B cell (CL0002048)
    Fold Change: 1.08
    Marker Score: 1272
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 1.07
    Marker Score: 620

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Other Information

**Key Characteristics** NRIP1 is a 251-kDa protein that belongs to the NRIP family of nuclear receptor-interacting proteins. It contains a unique combination of protein-protein interaction domains, including a nuclear receptor-binding domain, a histone deacetylase-binding domain, and a sumoylation domain. These domains enable NRIP1 to interact with various nuclear receptors, histone deacetylases, and sumoylation enzymes, thereby modulating gene expression and cellular processes. NRIP1 is also characterized by its ability to bind to specific DNA sequences, including those involved in the regulation of gluconeogenesis and lipogenesis. Its expression is regulated by various transcription factors, including estrogen receptors, glucocorticoid receptors, and retinoid X receptors. **Pathways and Functions** NRIP1 is involved in several cellular pathways, including: 1. **Circadian rhythm regulation**: NRIP1 interacts with the circadian clock protein BMAL1 to regulate the expression of genes involved in gluconeogenesis and lipogenesis. 2. **Estrogen-dependent gene expression**: NRIP1 binds to estrogen receptors to regulate the expression of genes involved in metabolism and cell growth. 3. **Heme signaling**: NRIP1 interacts with heme oxygenase-1 (HO-1) to regulate the expression of genes involved in oxidative stress response. 4. **Histone deacetylase activity**: NRIP1 binds to histone deacetylases to regulate chromatin structure and gene expression. 5. **Sumoylation**: NRIP1 is a sumoylation enzyme that modifies transcription cofactors and regulates gene expression. **Clinical Significance** NRIP1 has been implicated in various diseases, including: 1. **Metabolic disorders**: NRIP1 regulates gluconeogenesis and lipogenesis, making it a potential target for the treatment of metabolic disorders, such as type 2 diabetes and obesity. 2. **Cancer**: NRIP1 has been shown to regulate the expression of genes involved in cancer progression and metastasis. 3. **Neurological disorders**: NRIP1 has been implicated in the regulation of gene expression in neurons and glial cells, making it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Inflammatory diseases**: NRIP1 has been shown to regulate the expression of genes involved in inflammation, making it a potential target for the treatment of inflammatory diseases, such as arthritis and asthma. In conclusion, NRIP1 is a multifunctional protein that plays a crucial role in various cellular processes, including gene regulation, metabolism, and stress response. Its dysregulation has been implicated in various diseases, making it a potential target for the treatment of metabolic disorders, cancer, neurological disorders, and inflammatory diseases.

Genular Protein ID: 3361490176

Symbol: NRIP1_HUMAN

Name: Nuclear receptor-interacting protein 1

UniProtKB Accession Codes:

P48552 Q8IWE8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 5 EPD 1 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 13 PDBsum 11 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 6 RefSeq 12 SAM 1 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7641693

Title: Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

PubMed ID: 7641693

DOI: 10.1002/j.1460-2075.1995.tb00044.x

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9556573

Title: Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4.

PubMed ID: 9556573

DOI: 10.1074/jbc.273.18.10948

PubMed ID: 10364267

Title: Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids.

PubMed ID: 10364267

DOI: 10.1074/jbc.274.25.18121

PubMed ID: 11509661

Title: Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP.

PubMed ID: 11509661

DOI: 10.1128/mcb.21.18.6181-6188.2001

PubMed ID: 11266503

Title: Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140.

PubMed ID: 11266503

DOI: 10.1210/mend.15.4.0624

PubMed ID: 11518808

Title: A new human MR splice variant is a ligand-independent transactivator modulating corticosteroid action.

PubMed ID: 11518808

DOI: 10.1210/mend.15.9.0689

PubMed ID: 12773562

Title: Regulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140.

PubMed ID: 12773562

DOI: 10.1128/mcb.23.12.4187-4198.2003

PubMed ID: 12554755

Title: Receptor-interacting protein 140 binds c-Jun and inhibits estradiol-induced activator protein-1 activity by reversing glucocorticoid receptor-interacting protein 1 effect.

PubMed ID: 12554755

DOI: 10.1210/me.2002-0324

PubMed ID: 14736873

Title: Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.

PubMed ID: 14736873

DOI: 10.1074/jbc.m313906200

PubMed ID: 15060175

Title: Multiple domains of the receptor-interacting protein 140 contribute to transcription inhibition.

PubMed ID: 15060175

DOI: 10.1093/nar/gkh524

PubMed ID: 16887930

Title: Modulation of testicular receptor 4 activity by mitogen-activated protein kinase-mediated phosphorylation.

PubMed ID: 16887930

DOI: 10.1074/mcp.m600180-mcp200

PubMed ID: 17085477

Title: ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.

PubMed ID: 17085477

DOI: 10.1093/nar/gkl875

PubMed ID: 21628546

Title: Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140).

PubMed ID: 21628546

DOI: 10.1177/0748730411401579

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28381549

Title: A dominant mutation in nuclear receptor interacting protein 1 causes urinary tract malformations via dysregulation of retinoic acid signaling.

PubMed ID: 28381549

DOI: 10.1681/asn.2016060694

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30143558

Title: Whole-exome sequencing identifies causative mutations in families with congenital anomalies of the kidney and urinary tract.

PubMed ID: 30143558

DOI: 10.1681/asn.2017121265

PubMed ID: 16990259

Title: X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

PubMed ID: 16990259

DOI: 10.1074/jbc.m608410200

PubMed ID: 16131398

Title: Preliminary molecular genetic analysis of the receptor interacting protein 140 (RIP140) in women affected by endometriosis.

PubMed ID: 16131398

DOI: 10.1186/1743-1050-2-11

Sequence Information:

  • Length: 1158
  • Mass: 126942
  • Checksum: 81FC424968E9A5F6
  • Sequence:
    • MTHGEELGSD VHQDSIVLTY LEGLLMHQAA GGSGTAVDKK SAGHNEEDQN FNISGSAFPT 
CQSNGPVLNT HTYQGSGMLH LKKARLLQSS EDWNAAKRKR LSDSIMNLNV KKEALLAGMV 
DSVPKGKQDS TLLASLLQSF SSRLQTVALS QQIRQSLKEQ GYALSHDSLK VEKDLRCYGV 
ASSHLKTLLK KSKVKDQKPD TNLPDVTKNL IRDRFAESPH HVGQSGTKVM SEPLSCAARL 
QAVASMVEKR ASPATSPKPS VACSQLALLL SSEAHLQQYS REHALKTQNA NQAASERLAA 
MARLQENGQK DVGSYQLPKG MSSHLNGQAR TSSSKLMASK SSATVFQNPM GIIPSSPKNA 
GYKNSLERNN IKQAANNSLL LHLLKSQTIP KPMNGHSHSE RGSIFEESST PTTIDEYSDN 
NPSFTDDSSG DESSYSNCVP IDLSCKHRTE KSESDQPVSL DNFTQSLLNT WDPKVPDVDI 
KEDQDTSKNS KLNSHQKVTL LQLLLGHKNE ENVEKNTSPQ GVHNDVSKFN TQNYARTSVI 
ESPSTNRTTP VSTPPLLTSS KAGSPINLSQ HSLVIKWNSP PYVCSTQSEK LTNTASNHSM 
DLTKSKDPPG EKPAQNEGAQ NSATFSASKL LQNLAQCGMQ SSMSVEEQRP SKQLLTGNTD 
KPIGMIDRLN SPLLSNKTNA VEENKAFSSQ PTGPEPGLSG SEIENLLERR TVLQLLLGNP 
NKGKSEKKEK TPLRDESTQE HSERALSEQI LMVKIKSEPC DDLQIPNTNV HLSHDAKSAP 
FLGMAPAVQR SAPALPVSED FKSEPVSPQD FSFSKNGLLS RLLRQNQDSY LADDSDRSHR 
NNEMALLESK NLCMVPKKRK LYTEPLENPF KKMKNNIVDA ANNHSAPEVL YGSLLNQEEL 
KFSRNDLEFK YPAGHGSASE SEHRSWARES KSFNVLKQLL LSENCVRDLS PHRSNSVADS 
KKKGHKNNVT NSKPEFSISS LNGLMYSSTQ PSSCMDNRTF SYPGVVKTPV SPTFPEHLGC 
AGSRPESGLL NGCSMPSEKG PIKWVITDAE KNEYEKDSPR LTKTNPILYY MLQKGGNSVT 
SRETQDKDIW REASSAESVS QVTAKEELLP TAETKASFFN LRSPYNSHMG NNASRPHSAN 
GEVYGLLGSV LTIKKESE

Genular Protein ID: 3741089316

Symbol: A8K171_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K171

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 4 Genevisible 1 GenomeRNAi 1 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 7 PharmGKB 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 1158
  • Mass: 126832
  • Checksum: C11FEB82EE5A09D4
  • Sequence:
    • MTHGEELGSD VHQDSIVLTY LEGLLMHQAA GGSGTAVDKK SAGHNEEDQN FNISGSAFPT 
CQSNVPVLNT HTYQGSGMLH LKKARLLQSS EDWNAAKRKR LSDSIMNLNV KKEALLAGMV 
DSVPKGKQDS TLLASLLQSF SSRLQTVALS QQIRQSLKEQ GYALSHDSLK VEKDLRCYGV 
ASSHLKTLLK KSKVKDQKPD TNLPDVTKNL IRDRFAESPH HVGQSGTKVM SEPLSCAARL 
QAVASMVEKR ASPATSPKPS VACSQLALLL SSEAHLQQYS REHALKTQNA NQAASERLAA 
MARLQENGQK DVGSYQLPKG MSSHLNGQAR TSSSKLMASK SSATVFQNPM GIIPSSPKNA 
GYKNSLERNN IKQAANNSLL LHLLKSQTIP KPMNGHSHSE RGSIFEESST PTTIDEYSDN 
NPSFTDDSSG DESSYSNCVP IDLSCKHGTE KSESDQPVSL DNFTQSLLNT WDPKVPDVDI 
KEDQDTSKNS KLNSHQKVTL LQLLLGHKNE ENVEKNTSPQ GVHNDVSKFN TQNYARTSVI 
ESPSTNRTTP VSTPPLLTSS KAGSPINLSQ HSLVIKWNSP PYVCSTQSEK LTNTASNHSM 
DLTKSKDPPG EKPAQNEGAQ NSATFSASKL LQNLAQCGMQ SSMSVEEQRP SKQLLTGNTD 
KPIGMIDRLN SPLLSNKTNA VEENKAFSSQ PTGPEPGLSG SEIENLLERR TVLQLLLGNP 
NKGKSEKKEK TPLRDESTQE HSERALSEQI LMVKIKSEPC DDLQIPNTNV HLSHDAKSAP 
FLGMAPAVQR SAPALPVSED FKSEPVSPQD FSFSKNGLLS RLLRQNQDSY LADDSDRSHR 
NNEMALLESK NLCMVPKKRK LYTEPLENPF KKMKNNIVDA ANNHSAPEVL YGSLLNQEEL 
KFSRNDLEFK YPAGHGSASE SEHRSWARES KSFNVLKQLL LSENCVRDLS PHRSNSVADS 
KKKGHKNNVT NSKPEFSISS LNGLMYSSTQ PSSCMDNRTF SYPGVVKTPV SPTFPEHLGC 
AGSRPESGLL NGCSMPSEKG PIKWVITDAE KNEYEKDSPR LTKTNPILYY MLQKGGNSVT 
SRETQDKDIW REASSAESVS QVTAKEELLP TAETKASFFN LRSPYNSHMG NNASCPHSAN 
GEVYGLLGSV LTIKKESE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.