Details for: NRIP1

Gene ID: 8204

Symbol: NRIP1

Ensembl ID: ENSG00000180530

Description: nuclear receptor interacting protein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 343.7585
    Cell Significance Index: -53.4700
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 169.3322
    Cell Significance Index: -42.9500
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 113.0003
    Cell Significance Index: -53.3500
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 99.4974
    Cell Significance Index: -51.1800
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 79.5056
    Cell Significance Index: -53.3500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 43.7810
    Cell Significance Index: -53.9800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 19.0641
    Cell Significance Index: -51.0700
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 17.6008
    Cell Significance Index: -54.0600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 13.7099
    Cell Significance Index: -54.1000
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.6670
    Cell Significance Index: -16.7800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 4.8417
    Cell Significance Index: 111.8600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 3.8052
    Cell Significance Index: 213.5300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.9532
    Cell Significance Index: 79.1300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.3931
    Cell Significance Index: 32.6500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.2142
    Cell Significance Index: 439.4100
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.1584
    Cell Significance Index: 129.5800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 2.1538
    Cell Significance Index: 13.2600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 2.0529
    Cell Significance Index: 132.4400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.0127
    Cell Significance Index: 403.7400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.5826
    Cell Significance Index: 71.7400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.5206
    Cell Significance Index: 1372.9500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 1.4504
    Cell Significance Index: 17.2900
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.4131
    Cell Significance Index: 8.7800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.3241
    Cell Significance Index: 22.3100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.2677
    Cell Significance Index: 36.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.1919
    Cell Significance Index: 31.8300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.0282
    Cell Significance Index: 29.6300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.9312
    Cell Significance Index: 18.1800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.9279
    Cell Significance Index: 58.4800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9266
    Cell Significance Index: 332.3400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.8913
    Cell Significance Index: 68.4000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.8696
    Cell Significance Index: 94.5900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.8348
    Cell Significance Index: 455.8900
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: 0.8293
    Cell Significance Index: 10.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.8207
    Cell Significance Index: 147.9400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.7996
    Cell Significance Index: 109.8100
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7567
    Cell Significance Index: 123.0700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.7374
    Cell Significance Index: 90.6700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.6889
    Cell Significance Index: 18.7500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.6116
    Cell Significance Index: 37.5900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.5629
    Cell Significance Index: 14.4700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4726
    Cell Significance Index: 46.7500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4709
    Cell Significance Index: 24.4600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.3926
    Cell Significance Index: 29.2600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.3226
    Cell Significance Index: 41.3500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3179
    Cell Significance Index: 60.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2943
    Cell Significance Index: 50.2600
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2346
    Cell Significance Index: 6.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2065
    Cell Significance Index: 91.2900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1985
    Cell Significance Index: 4.7600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.1916
    Cell Significance Index: 121.6900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1542
    Cell Significance Index: 5.4200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.1265
    Cell Significance Index: 238.2000
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.1124
    Cell Significance Index: 3.1400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.1108
    Cell Significance Index: 1.0200
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.0745
    Cell Significance Index: 0.4500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0624
    Cell Significance Index: 2.9400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0232
    Cell Significance Index: 1.0800
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0012
    Cell Significance Index: 0.0100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0043
    Cell Significance Index: -3.1600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0073
    Cell Significance Index: -3.2900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0084
    Cell Significance Index: -15.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0121
    Cell Significance Index: -8.9300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0127
    Cell Significance Index: -19.6200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0143
    Cell Significance Index: -19.4000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0151
    Cell Significance Index: -2.1900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0359
    Cell Significance Index: -22.4200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0390
    Cell Significance Index: -0.8100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0572
    Cell Significance Index: -43.3200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0659
    Cell Significance Index: -37.1600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1186
    Cell Significance Index: -15.3300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1207
    Cell Significance Index: -5.3400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1217
    Cell Significance Index: -13.8900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1233
    Cell Significance Index: -4.6700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1319
    Cell Significance Index: -27.7800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1439
    Cell Significance Index: -3.8500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1522
    Cell Significance Index: -15.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1622
    Cell Significance Index: -46.6600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2070
    Cell Significance Index: -4.4300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.2156
    Cell Significance Index: -24.7100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2195
    Cell Significance Index: -14.7600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2659
    Cell Significance Index: -31.3600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2667
    Cell Significance Index: -4.5700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2772
    Cell Significance Index: -6.9300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.3031
    Cell Significance Index: -35.3200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3286
    Cell Significance Index: -7.1200
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: -0.4025
    Cell Significance Index: -4.0600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4727
    Cell Significance Index: -13.4900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.4727
    Cell Significance Index: -49.2200
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.4810
    Cell Significance Index: -7.1000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.4832
    Cell Significance Index: -10.2900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.5146
    Cell Significance Index: -40.7600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.5383
    Cell Significance Index: -17.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5732
    Cell Significance Index: -40.5400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5826
    Cell Significance Index: -35.7200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6453
    Cell Significance Index: -33.8800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.6720
    Cell Significance Index: -10.0700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.7197
    Cell Significance Index: -14.2300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7708
    Cell Significance Index: -24.5500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7859
    Cell Significance Index: -25.7300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** NRIP1 is a 251-kDa protein that belongs to the NRIP family of nuclear receptor-interacting proteins. It contains a unique combination of protein-protein interaction domains, including a nuclear receptor-binding domain, a histone deacetylase-binding domain, and a sumoylation domain. These domains enable NRIP1 to interact with various nuclear receptors, histone deacetylases, and sumoylation enzymes, thereby modulating gene expression and cellular processes. NRIP1 is also characterized by its ability to bind to specific DNA sequences, including those involved in the regulation of gluconeogenesis and lipogenesis. Its expression is regulated by various transcription factors, including estrogen receptors, glucocorticoid receptors, and retinoid X receptors. **Pathways and Functions** NRIP1 is involved in several cellular pathways, including: 1. **Circadian rhythm regulation**: NRIP1 interacts with the circadian clock protein BMAL1 to regulate the expression of genes involved in gluconeogenesis and lipogenesis. 2. **Estrogen-dependent gene expression**: NRIP1 binds to estrogen receptors to regulate the expression of genes involved in metabolism and cell growth. 3. **Heme signaling**: NRIP1 interacts with heme oxygenase-1 (HO-1) to regulate the expression of genes involved in oxidative stress response. 4. **Histone deacetylase activity**: NRIP1 binds to histone deacetylases to regulate chromatin structure and gene expression. 5. **Sumoylation**: NRIP1 is a sumoylation enzyme that modifies transcription cofactors and regulates gene expression. **Clinical Significance** NRIP1 has been implicated in various diseases, including: 1. **Metabolic disorders**: NRIP1 regulates gluconeogenesis and lipogenesis, making it a potential target for the treatment of metabolic disorders, such as type 2 diabetes and obesity. 2. **Cancer**: NRIP1 has been shown to regulate the expression of genes involved in cancer progression and metastasis. 3. **Neurological disorders**: NRIP1 has been implicated in the regulation of gene expression in neurons and glial cells, making it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 4. **Inflammatory diseases**: NRIP1 has been shown to regulate the expression of genes involved in inflammation, making it a potential target for the treatment of inflammatory diseases, such as arthritis and asthma. In conclusion, NRIP1 is a multifunctional protein that plays a crucial role in various cellular processes, including gene regulation, metabolism, and stress response. Its dysregulation has been implicated in various diseases, making it a potential target for the treatment of metabolic disorders, cancer, neurological disorders, and inflammatory diseases.

Genular Protein ID: 3361490176

Symbol: NRIP1_HUMAN

Name: Nuclear receptor-interacting protein 1

UniProtKB Accession Codes:

P48552 Q8IWE8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 1 EMBL 5 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 11 PDBsum 11 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 6 RefSeq 12 SIGNOR 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7641693

Title: Nuclear factor RIP140 modulates transcriptional activation by the estrogen receptor.

PubMed ID: 7641693

DOI: 10.1002/j.1460-2075.1995.tb00044.x

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9556573

Title: Regulation of peroxisome proliferator-activated receptor alpha-induced transactivation by the nuclear orphan receptor TAK1/TR4.

PubMed ID: 9556573

DOI: 10.1074/jbc.273.18.10948

PubMed ID: 10364267

Title: Receptor interacting protein RIP140 inhibits both positive and negative gene regulation by glucocorticoids.

PubMed ID: 10364267

DOI: 10.1074/jbc.274.25.18121

PubMed ID: 11509661

Title: Acetylation of nuclear hormone receptor-interacting protein RIP140 regulates binding of the transcriptional corepressor CtBP.

PubMed ID: 11509661

DOI: 10.1128/mcb.21.18.6181-6188.2001

PubMed ID: 11266503

Title: Regulation of glucocorticoid receptor activity by 14-3-3-dependent intracellular relocalization of the corepressor RIP140.

PubMed ID: 11266503

DOI: 10.1210/mend.15.4.0624

PubMed ID: 11518808

Title: A new human MR splice variant is a ligand-independent transactivator modulating corticosteroid action.

PubMed ID: 11518808

DOI: 10.1210/mend.15.9.0689

PubMed ID: 12773562

Title: Regulation of subnuclear localization is associated with a mechanism for nuclear receptor corepression by RIP140.

PubMed ID: 12773562

DOI: 10.1128/mcb.23.12.4187-4198.2003

PubMed ID: 12554755

Title: Receptor-interacting protein 140 binds c-Jun and inhibits estradiol-induced activator protein-1 activity by reversing glucocorticoid receptor-interacting protein 1 effect.

PubMed ID: 12554755

DOI: 10.1210/me.2002-0324

PubMed ID: 14736873

Title: Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140.

PubMed ID: 14736873

DOI: 10.1074/jbc.m313906200

PubMed ID: 15060175

Title: Multiple domains of the receptor-interacting protein 140 contribute to transcription inhibition.

PubMed ID: 15060175

DOI: 10.1093/nar/gkh524

PubMed ID: 16887930

Title: Modulation of testicular receptor 4 activity by mitogen-activated protein kinase-mediated phosphorylation.

PubMed ID: 16887930

DOI: 10.1074/mcp.m600180-mcp200

PubMed ID: 17085477

Title: ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases.

PubMed ID: 17085477

DOI: 10.1093/nar/gkl875

PubMed ID: 21628546

Title: Modulation of clock gene expression by the transcriptional coregulator receptor interacting protein 140 (RIP140).

PubMed ID: 21628546

DOI: 10.1177/0748730411401579

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25218447

Title: Uncovering global SUMOylation signaling networks in a site-specific manner.

PubMed ID: 25218447

DOI: 10.1038/nsmb.2890

PubMed ID: 28381549

Title: A dominant mutation in nuclear receptor interacting protein 1 causes urinary tract malformations via dysregulation of retinoic acid signaling.

PubMed ID: 28381549

DOI: 10.1681/asn.2016060694

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 30143558

Title: Whole-exome sequencing identifies causative mutations in families with congenital anomalies of the kidney and urinary tract.

PubMed ID: 30143558

DOI: 10.1681/asn.2017121265

PubMed ID: 16990259

Title: X-ray crystal structures of the estrogen-related receptor-gamma ligand binding domain in three functional states reveal the molecular basis of small molecule regulation.

PubMed ID: 16990259

DOI: 10.1074/jbc.m608410200

PubMed ID: 16131398

Title: Preliminary molecular genetic analysis of the receptor interacting protein 140 (RIP140) in women affected by endometriosis.

PubMed ID: 16131398

DOI: 10.1186/1743-1050-2-11

Sequence Information:

  • Length: 1158
  • Mass: 126942
  • Checksum: 81FC424968E9A5F6
  • Sequence:
    • MTHGEELGSD VHQDSIVLTY LEGLLMHQAA GGSGTAVDKK SAGHNEEDQN FNISGSAFPT 
CQSNGPVLNT HTYQGSGMLH LKKARLLQSS EDWNAAKRKR LSDSIMNLNV KKEALLAGMV 
DSVPKGKQDS TLLASLLQSF SSRLQTVALS QQIRQSLKEQ GYALSHDSLK VEKDLRCYGV 
ASSHLKTLLK KSKVKDQKPD TNLPDVTKNL IRDRFAESPH HVGQSGTKVM SEPLSCAARL 
QAVASMVEKR ASPATSPKPS VACSQLALLL SSEAHLQQYS REHALKTQNA NQAASERLAA 
MARLQENGQK DVGSYQLPKG MSSHLNGQAR TSSSKLMASK SSATVFQNPM GIIPSSPKNA 
GYKNSLERNN IKQAANNSLL LHLLKSQTIP KPMNGHSHSE RGSIFEESST PTTIDEYSDN 
NPSFTDDSSG DESSYSNCVP IDLSCKHRTE KSESDQPVSL DNFTQSLLNT WDPKVPDVDI 
KEDQDTSKNS KLNSHQKVTL LQLLLGHKNE ENVEKNTSPQ GVHNDVSKFN TQNYARTSVI 
ESPSTNRTTP VSTPPLLTSS KAGSPINLSQ HSLVIKWNSP PYVCSTQSEK LTNTASNHSM 
DLTKSKDPPG EKPAQNEGAQ NSATFSASKL LQNLAQCGMQ SSMSVEEQRP SKQLLTGNTD 
KPIGMIDRLN SPLLSNKTNA VEENKAFSSQ PTGPEPGLSG SEIENLLERR TVLQLLLGNP 
NKGKSEKKEK TPLRDESTQE HSERALSEQI LMVKIKSEPC DDLQIPNTNV HLSHDAKSAP 
FLGMAPAVQR SAPALPVSED FKSEPVSPQD FSFSKNGLLS RLLRQNQDSY LADDSDRSHR 
NNEMALLESK NLCMVPKKRK LYTEPLENPF KKMKNNIVDA ANNHSAPEVL YGSLLNQEEL 
KFSRNDLEFK YPAGHGSASE SEHRSWARES KSFNVLKQLL LSENCVRDLS PHRSNSVADS 
KKKGHKNNVT NSKPEFSISS LNGLMYSSTQ PSSCMDNRTF SYPGVVKTPV SPTFPEHLGC 
AGSRPESGLL NGCSMPSEKG PIKWVITDAE KNEYEKDSPR LTKTNPILYY MLQKGGNSVT 
SRETQDKDIW REASSAESVS QVTAKEELLP TAETKASFFN LRSPYNSHMG NNASRPHSAN 
GEVYGLLGSV LTIKKESE

Genular Protein ID: 3741089316

Symbol: A8K171_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K171

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 Pfam 7 PharmGKB 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 1158
  • Mass: 126832
  • Checksum: C11FEB82EE5A09D4
  • Sequence:
    • MTHGEELGSD VHQDSIVLTY LEGLLMHQAA GGSGTAVDKK SAGHNEEDQN FNISGSAFPT 
CQSNVPVLNT HTYQGSGMLH LKKARLLQSS EDWNAAKRKR LSDSIMNLNV KKEALLAGMV 
DSVPKGKQDS TLLASLLQSF SSRLQTVALS QQIRQSLKEQ GYALSHDSLK VEKDLRCYGV 
ASSHLKTLLK KSKVKDQKPD TNLPDVTKNL IRDRFAESPH HVGQSGTKVM SEPLSCAARL 
QAVASMVEKR ASPATSPKPS VACSQLALLL SSEAHLQQYS REHALKTQNA NQAASERLAA 
MARLQENGQK DVGSYQLPKG MSSHLNGQAR TSSSKLMASK SSATVFQNPM GIIPSSPKNA 
GYKNSLERNN IKQAANNSLL LHLLKSQTIP KPMNGHSHSE RGSIFEESST PTTIDEYSDN 
NPSFTDDSSG DESSYSNCVP IDLSCKHGTE KSESDQPVSL DNFTQSLLNT WDPKVPDVDI 
KEDQDTSKNS KLNSHQKVTL LQLLLGHKNE ENVEKNTSPQ GVHNDVSKFN TQNYARTSVI 
ESPSTNRTTP VSTPPLLTSS KAGSPINLSQ HSLVIKWNSP PYVCSTQSEK LTNTASNHSM 
DLTKSKDPPG EKPAQNEGAQ NSATFSASKL LQNLAQCGMQ SSMSVEEQRP SKQLLTGNTD 
KPIGMIDRLN SPLLSNKTNA VEENKAFSSQ PTGPEPGLSG SEIENLLERR TVLQLLLGNP 
NKGKSEKKEK TPLRDESTQE HSERALSEQI LMVKIKSEPC DDLQIPNTNV HLSHDAKSAP 
FLGMAPAVQR SAPALPVSED FKSEPVSPQD FSFSKNGLLS RLLRQNQDSY LADDSDRSHR 
NNEMALLESK NLCMVPKKRK LYTEPLENPF KKMKNNIVDA ANNHSAPEVL YGSLLNQEEL 
KFSRNDLEFK YPAGHGSASE SEHRSWARES KSFNVLKQLL LSENCVRDLS PHRSNSVADS 
KKKGHKNNVT NSKPEFSISS LNGLMYSSTQ PSSCMDNRTF SYPGVVKTPV SPTFPEHLGC 
AGSRPESGLL NGCSMPSEKG PIKWVITDAE KNEYEKDSPR LTKTNPILYY MLQKGGNSVT 
SRETQDKDIW REASSAESVS QVTAKEELLP TAETKASFFN LRSPYNSHMG NNASCPHSAN 
GEVYGLLGSV LTIKKESE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.