Details for: LGR5

Gene ID: 8549

Symbol: LGR5

Ensembl ID: ENSG00000139292

Description: leucine rich repeat containing G protein-coupled receptor 5

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.8931
    Cell Significance Index: 100.0700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 3.5997
    Cell Significance Index: 87.8300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.5029
    Cell Significance Index: 140.4500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 2.4915
    Cell Significance Index: 494.4500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 2.3966
    Cell Significance Index: 55.3700
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 1.7984
    Cell Significance Index: 24.9500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.3957
    Cell Significance Index: 34.8100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.3651
    Cell Significance Index: 36.4500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.0680
    Cell Significance Index: 964.3700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0096
    Cell Significance Index: 60.6100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.9946
    Cell Significance Index: 144.5800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8320
    Cell Significance Index: 135.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.5910
    Cell Significance Index: 322.7400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.4458
    Cell Significance Index: 12.8500
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.3987
    Cell Significance Index: 5.6000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.3414
    Cell Significance Index: 8.2700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.2980
    Cell Significance Index: 4.6100
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.2765
    Cell Significance Index: 4.6500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2665
    Cell Significance Index: 117.8400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2357
    Cell Significance Index: 5.0200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2306
    Cell Significance Index: 22.8100
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.2043
    Cell Significance Index: 2.3800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1976
    Cell Significance Index: 37.6000
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0755
    Cell Significance Index: 1.5800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0646
    Cell Significance Index: 44.6700
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0322
    Cell Significance Index: 1.4600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0154
    Cell Significance Index: 1.8000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0145
    Cell Significance Index: 0.5100
  • Cell Name: L5 intratelencephalic projecting glutamatergic neuron (CL4030064)
    Fold Change: 0.0093
    Cell Significance Index: 0.1000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0031
    Cell Significance Index: 1.1100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0028
    Cell Significance Index: 0.5600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0053
    Cell Significance Index: -9.9400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0079
    Cell Significance Index: -14.5400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0107
    Cell Significance Index: -16.4800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0124
    Cell Significance Index: -16.8400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0184
    Cell Significance Index: -11.6900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0212
    Cell Significance Index: -15.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0235
    Cell Significance Index: -14.6600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0246
    Cell Significance Index: -1.0700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0309
    Cell Significance Index: -17.4500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0310
    Cell Significance Index: -14.0800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0353
    Cell Significance Index: -10.1500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0367
    Cell Significance Index: -4.7100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0614
    Cell Significance Index: -11.0700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0739
    Cell Significance Index: -1.6000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0761
    Cell Significance Index: -16.0200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0787
    Cell Significance Index: -2.5200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0795
    Cell Significance Index: -10.9200
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0807
    Cell Significance Index: -4.0800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0898
    Cell Significance Index: -2.5100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0899
    Cell Significance Index: -5.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0903
    Cell Significance Index: -15.4200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1069
    Cell Significance Index: -13.1500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1172
    Cell Significance Index: -15.1400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1257
    Cell Significance Index: -14.4000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1266
    Cell Significance Index: -13.1800
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1275
    Cell Significance Index: -1.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1432
    Cell Significance Index: -3.5800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1438
    Cell Significance Index: -2.0600
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1459
    Cell Significance Index: -10.3200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1555
    Cell Significance Index: -6.3700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1572
    Cell Significance Index: -16.0600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1575
    Cell Significance Index: -4.2200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1725
    Cell Significance Index: -11.6000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1954
    Cell Significance Index: -2.9500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2034
    Cell Significance Index: -15.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2049
    Cell Significance Index: -15.7200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2161
    Cell Significance Index: -6.3700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2258
    Cell Significance Index: -14.5700
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.2322
    Cell Significance Index: -2.4900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2354
    Cell Significance Index: -14.4700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2360
    Cell Significance Index: -4.9000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2494
    Cell Significance Index: -6.2200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2525
    Cell Significance Index: -11.1700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2596
    Cell Significance Index: -13.5200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2610
    Cell Significance Index: -5.5400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2789
    Cell Significance Index: -1.8900
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2810
    Cell Significance Index: -9.2000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2881
    Cell Significance Index: -15.1300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3094
    Cell Significance Index: -14.5400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3130
    Cell Significance Index: -16.2600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.3168
    Cell Significance Index: -6.3600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3226
    Cell Significance Index: -11.3000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3280
    Cell Significance Index: -12.4200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3335
    Cell Significance Index: -15.5500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3363
    Cell Significance Index: -6.6500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3683
    Cell Significance Index: -13.5200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3724
    Cell Significance Index: -11.8600
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.3915
    Cell Significance Index: -4.3800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4195
    Cell Significance Index: -11.0300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4261
    Cell Significance Index: -12.1600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.4307
    Cell Significance Index: -8.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.4417
    Cell Significance Index: -7.5700
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4452
    Cell Significance Index: -15.4700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.4591
    Cell Significance Index: -14.5200
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.4834
    Cell Significance Index: -4.3700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4919
    Cell Significance Index: -14.1000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.4998
    Cell Significance Index: -13.3700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.5129
    Cell Significance Index: -12.8100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.5191
    Cell Significance Index: -10.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Leucine-rich repeat-containing G protein-coupled receptor**: LGR5 possesses a characteristic leucine-rich repeat domain, which is essential for its interaction with β-catenin and the Wnt signaling pathway. 2. **Wnt signaling pathway co-receptor**: LGR5 acts as a co-receptor to facilitate the activation of canonical Wnt/β-catenin signaling, promoting cell growth and survival. 3. **Epithelial cell proliferation and differentiation**: LGR5 plays a crucial role in regulating epithelial cell proliferation, differentiation, and development in various tissues, including the skin, hair follicles, and inner ear. 4. **Tissue-specific expression**: LGR5 is significantly expressed in syncytiotrophoblast cells, neuroendocrine cells, granulocyte-monocyte progenitor cells, and other epithelial cells, highlighting its diverse roles in different tissues. **Pathways and Functions:** 1. **Wnt/β-catenin signaling pathway**: LGR5 acts as a co-receptor to facilitate the activation of canonical Wnt/β-catenin signaling, promoting cell growth and survival. 2. **Epithelial cell proliferation and differentiation**: LGR5 regulates epithelial cell proliferation, differentiation, and development in various tissues, including the skin, hair follicles, and inner ear. 3. **G protein-coupled receptor activity**: LGR5 exhibits G protein-coupled receptor activity, allowing it to interact with G-proteins and modulate downstream signaling pathways. 4. **Transcriptional regulation**: LGR5 acts as a transcriptional regulator, influencing the expression of target genes involved in cell proliferation, differentiation, and survival. **Clinical Significance:** 1. **Cancer**: LGR5 has been implicated in the development and progression of various cancers, including colorectal, breast, and prostate cancers. Targeting LGR5 has emerged as a promising therapeutic strategy for cancer treatment. 2. **Gastrointestinal disorders**: LGR5 has been linked to gastrointestinal disorders, such as inflammatory bowel disease (IBD) and colorectal cancer. Understanding LGR5's role in these diseases may lead to the development of novel therapeutic approaches. 3. **Regenerative medicine**: LGR5's role in epithelial cell proliferation and differentiation makes it an attractive target for regenerative medicine applications, such as tissue engineering and wound healing. 4. **Neurological disorders**: LGR5 has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease. Further research is needed to elucidate its role in these diseases and explore potential therapeutic targets. In conclusion, LGR5 is a crucial G protein-coupled receptor that plays a vital role in regulating epithelial cell proliferation, differentiation, and development. Its involvement in various developmental processes and diseases highlights the importance of understanding its mechanisms and potential therapeutic applications.

Genular Protein ID: 1189951367

Symbol: LGR5_HUMAN

Name: Leucine-rich repeat-containing G-protein coupled receptor 5

UniProtKB Accession Codes:

O75473 D8MCT0 Q4VAM0 Q4VAM2 Q9UP75

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 9 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 1 PDB 7 PDBsum 7 PIR 1 PRINTS 2 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 1 RefSeq 3 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9642114

Title: Identification and cloning of an orphan G protein-coupled receptor of the glycoprotein hormone receptor subfamily.

PubMed ID: 9642114

DOI: 10.1006/bbrc.1998.8774

PubMed ID: 9849958

Title: Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region.

PubMed ID: 9849958

DOI: 10.1210/mend.12.12.0211

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12601349

Title: Overexpression of orphan G-protein-coupled receptor, Gpr49, in human hepatocellular carcinomas with beta-catenin mutations.

PubMed ID: 12601349

DOI: 10.1053/jhep.2003.50029

PubMed ID: 16575208

Title: Identification of overexpression of orphan G protein-coupled receptor GPR49 in human colon and ovarian primary tumors.

PubMed ID: 16575208

DOI: 10.4161/cbt.5.4.2521

PubMed ID: 19030762

Title: Immunostaining of Lgr5, an intestinal stem cell marker, in normal and premalignant human gastrointestinal tissue.

PubMed ID: 19030762

DOI: 10.1100/tsw.2008.148

PubMed ID: 21909076

Title: LGR4 and LGR5 are R-spondin receptors mediating Wnt/beta-catenin and Wnt/PCP signalling.

PubMed ID: 21909076

DOI: 10.1038/embor.2011.175

PubMed ID: 21727895

Title: Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.

PubMed ID: 21727895

DOI: 10.1038/nature10337

PubMed ID: 21693646

Title: R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling.

PubMed ID: 21693646

DOI: 10.1073/pnas.1106083108

PubMed ID: 22815884

Title: R-Spondin potentiates Wnt/beta-catenin signaling through orphan receptors LGR4 and LGR5.

PubMed ID: 22815884

DOI: 10.1371/journal.pone.0040976

PubMed ID: 23439653

Title: Constitutive Internalization of the Leucine-rich G Protein-coupled Receptor-5 (LGR5) to the Trans-Golgi Network.

PubMed ID: 23439653

DOI: 10.1074/jbc.m112.447540

PubMed ID: 29769720

Title: RSPO2 inhibition of RNF43 and ZNRF3 governs limb development independently of LGR4/5/6.

PubMed ID: 29769720

DOI: 10.1038/s41586-018-0118-y

PubMed ID: 23809763

Title: Structure of stem cell growth factor R-spondin 1 in complex with the ectodomain of its receptor LGR5.

PubMed ID: 23809763

DOI: 10.1016/j.celrep.2013.06.009

PubMed ID: 23756651

Title: The structural basis of R-spondin recognition by LGR5 and RNF43.

PubMed ID: 23756651

DOI: 10.1101/gad.219915.113

Sequence Information:

  • Length: 907
  • Mass: 99998
  • Checksum: 822D5C5E6F0D9092
  • Sequence:
    • MDTSRLGVLL SLPVLLQLAT GGSSPRSGVL LRGCPTHCHC EPDGRMLLRV DCSDLGLSEL 
PSNLSVFTSY LDLSMNNISQ LLPNPLPSLR FLEELRLAGN ALTYIPKGAF TGLYSLKVLM 
LQNNQLRHVP TEALQNLRSL QSLRLDANHI SYVPPSCFSG LHSLRHLWLD DNALTEIPVQ 
AFRSLSALQA MTLALNKIHH IPDYAFGNLS SLVVLHLHNN RIHSLGKKCF DGLHSLETLD 
LNYNNLDEFP TAIRTLSNLK ELGFHSNNIR SIPEKAFVGN PSLITIHFYD NPIQFVGRSA 
FQHLPELRTL TLNGASQITE FPDLTGTANL ESLTLTGAQI SSLPQTVCNQ LPNLQVLDLS 
YNLLEDLPSF SVCQKLQKID LRHNEIYEIK VDTFQQLLSL RSLNLAWNKI AIIHPNAFST 
LPSLIKLDLS SNLLSSFPIT GLHGLTHLKL TGNHALQSLI SSENFPELKV IEMPYAYQCC 
AFGVCENAYK ISNQWNKGDN SSMDDLHKKD AGMFQAQDER DLEDFLLDFE EDLKALHSVQ 
CSPSPGPFKP CEHLLDGWLI RIGVWTIAVL ALTCNALVTS TVFRSPLYIS PIKLLIGVIA 
AVNMLTGVSS AVLAGVDAFT FGSFARHGAW WENGVGCHVI GFLSIFASES SVFLLTLAAL 
ERGFSVKYSA KFETKAPFSS LKVIILLCAL LALTMAAVPL LGGSKYGASP LCLPLPFGEP 
STMGYMVALI LLNSLCFLMM TIAYTKLYCN LDKGDLENIW DCSMVKHIAL LLFTNCILNC 
PVAFLSFSSL INLTFISPEV IKFILLVVVP LPACLNPLLY ILFNPHFKED LVSLRKQTYV 
WTRSKHPSLM SINSDDVEKQ SCDSTQALVT FTSSSITYDL PPSSVPSPAY PVTESCHLSS 
VAFVPCL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.