Details for: INPP4B
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 278.1185
Cell Significance Index: -43.2600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 164.9954
Cell Significance Index: -41.8500 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 91.5922
Cell Significance Index: -37.2100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 35.1189
Cell Significance Index: -43.3000 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 17.8808
Cell Significance Index: -54.9200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 11.4412
Cell Significance Index: -25.0400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 5.8602
Cell Significance Index: 449.7100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 5.6471
Cell Significance Index: 379.7100 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: 5.0892
Cell Significance Index: 31.3200 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 4.9081
Cell Significance Index: 63.6500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 4.8124
Cell Significance Index: 123.7000 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 4.6608
Cell Significance Index: 1671.7500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 3.6310
Cell Significance Index: 160.6100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 3.3593
Cell Significance Index: 127.2100 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: 3.1369
Cell Significance Index: 43.8700 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 2.6431
Cell Significance Index: 64.4900 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.5558
Cell Significance Index: 1767.6700 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 2.4878
Cell Significance Index: 66.6600 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: 2.3280
Cell Significance Index: 31.0600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 2.2871
Cell Significance Index: 57.1700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 2.2641
Cell Significance Index: 454.1800 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 2.0896
Cell Significance Index: 59.6300 - Cell Name: chandelier cell (CL4023083)
Fold Change: 1.9692
Cell Significance Index: 15.9000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 1.8410
Cell Significance Index: 3466.3900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 1.7685
Cell Significance Index: 26.6500 - Cell Name: corneal endothelial cell (CL0000132)
Fold Change: 1.3942
Cell Significance Index: 21.2100 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 1.3303
Cell Significance Index: 844.8900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.0276
Cell Significance Index: 101.6500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.9443
Cell Significance Index: 852.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: 0.9288
Cell Significance Index: 96.7100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.9181
Cell Significance Index: 47.6900 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: 0.7720
Cell Significance Index: 9.5800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.7397
Cell Significance Index: 10.9200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6627
Cell Significance Index: 40.7300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.5368
Cell Significance Index: 40.0100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.4988
Cell Significance Index: 54.2500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3831
Cell Significance Index: 23.0000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.3637
Cell Significance Index: 59.1600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.2327
Cell Significance Index: 5.5800 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.2030
Cell Significance Index: 92.1300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1999
Cell Significance Index: 36.0300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.1882
Cell Significance Index: 23.1500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1726
Cell Significance Index: 11.9400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.1402
Cell Significance Index: 215.8200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1158
Cell Significance Index: 3.3400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1013
Cell Significance Index: 3.5600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0684
Cell Significance Index: 93.0200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0649
Cell Significance Index: 35.4300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0645
Cell Significance Index: 118.9100 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: 0.0274
Cell Significance Index: 0.5500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0137
Cell Significance Index: -10.0700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0186
Cell Significance Index: -11.6000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0187
Cell Significance Index: -2.5700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0293
Cell Significance Index: -21.7100 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0329
Cell Significance Index: -0.4100 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0341
Cell Significance Index: -4.9600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0341
Cell Significance Index: -19.2400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0363
Cell Significance Index: -0.7700 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.0548
Cell Significance Index: -0.5100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0634
Cell Significance Index: -47.9600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0729
Cell Significance Index: -32.2500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0756
Cell Significance Index: -12.9100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.1099
Cell Significance Index: -4.9800 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.1277
Cell Significance Index: -3.7500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1292
Cell Significance Index: -37.1800 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1404
Cell Significance Index: -29.5700 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: -0.1507
Cell Significance Index: -0.9300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1526
Cell Significance Index: -30.2800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.2317
Cell Significance Index: -3.9700 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2391
Cell Significance Index: -27.3900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.2409
Cell Significance Index: -28.0800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2444
Cell Significance Index: -24.9700 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2630
Cell Significance Index: -3.3200 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2786
Cell Significance Index: -3.9900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.2848
Cell Significance Index: -6.1700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.3082
Cell Significance Index: -39.8200 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.3238
Cell Significance Index: -2.7200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3384
Cell Significance Index: -18.9900 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.3532
Cell Significance Index: -41.6500 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.4043
Cell Significance Index: -46.1500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.4253
Cell Significance Index: -54.5200 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4488
Cell Significance Index: -9.3100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.4506
Cell Significance Index: -35.6900 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.5287
Cell Significance Index: -5.0300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.5364
Cell Significance Index: -14.9900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.5378
Cell Significance Index: -28.0200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.5451
Cell Significance Index: -17.4600 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.5540
Cell Significance Index: -11.9700 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.5620
Cell Significance Index: -26.4200 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.5667
Cell Significance Index: -12.0700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.6059
Cell Significance Index: -11.9800 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.6233
Cell Significance Index: -19.8500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.6335
Cell Significance Index: -20.7400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.6378
Cell Significance Index: -17.0300 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.6631
Cell Significance Index: -7.9300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.6767
Cell Significance Index: -31.5500 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.6813
Cell Significance Index: -13.4100 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.6813
Cell Significance Index: -11.7800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.6815
Cell Significance Index: -43.9700 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.7216
Cell Significance Index: -37.8900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3826388075
Symbol: INP4B_HUMAN
Name: Inositol polyphosphate 4-phosphatase type II
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9295334
Title: The cDNA cloning and characterization of inositol polyphosphate 4-phosphatase type II. Evidence for conserved alternative splicing in the 4-phosphatase family.
PubMed ID: 9295334
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 19647222
Title: Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.
PubMed ID: 19647222
PubMed ID: 24070612
Title: Determinants of the tumor suppressor INPP4B protein and lipid phosphatase activities.
PubMed ID: 24070612
PubMed ID: 24591580
Title: Sequential breakdown of 3-phosphorylated phosphoinositides is essential for the completion of macropinocytosis.
PubMed ID: 24591580
Sequence Information:
- Length: 924
- Mass: 104738
- Checksum: 57DE9D98E0168D41
- Sequence:
MEIKEEGASE EGQHFLPTAQ ANDPGDCQFT SIQKTPNEPQ LEFILACKDL VAPVRDRKLN TLVQISVIHP VEQSLTRYSS TEIVEGTRDP LFLTGVTFPS EYPIYEETKI KLTVYDVKDK SHDTVRTSVL PEHKDPPPEV GRSFLGYASF KVGELLKSKE QLLVLSLRTS DGGKVVGTIE VSVVKMGEIE DGEADHITTD VQGQKCALVC ECTAPESVSG KDNLPFLNSV LKNPVCKLYR FPTSDNKWMR IREQMSESIL SFHIPKELIS LHIKEDLCRN QEIKELGELS PHWDNLRKNV LTHCDQMVNM YQDILTELSK ETGSSFKSSS SKGEKTLEFV PINLHLQRMQ VHSPHLKDAL YDVITVGAPA AHFQGFKNGG LRKLLHRFET ERRNTGYQFI YYSPENTAKA KEVLSNINQL QPLIATHADL LLNSASQHSP DSLKNSLKML SEKTELFVHA FKDQLVRSAL LALYTARPGG ILKKPPSPKS STEESSPQDQ PPVMRGQDSI PHHSDYDEEE WDRVWANVGK SLNCIIAMVD KLIERDGGSE GSGGNNDGEK EPSLTDAIPS HPREDWYEQL YPLILTLKDC MGEVVNRAKQ SLTFVLLQEL AYSLPQCLML TLRRDIVFSQ ALAGLVCGFI IKLQTSLYDP GFLQQLHTVG LIVQYEGLLS TYSDEIGMLE DMAVGISDLK KVAFKIIEAK SNDVLPVITG RREHYVVEVK LPARMFESLP LQIKEGQLLH VYPVLFNVGI NEQQTLAERF GDVSLQESIN QENFELLQEY YKIFMEKMPP DYISHFQEQN DLKALLENLL QNIQSKKRKN VEIMWLAATI CRKLNGIRFT CCKSAKDRTS MSVTLEQCSI LRDEHQLHKD FFIRALDCMR REGCRIENVL KNIKCRKYAF NMLQLMAFPK YYRPPEGTYG KADT
Genular Protein ID: 3726916394
Symbol: E7EQN9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 15815621
Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
PubMed ID: 15815621
DOI: 10.1038/nature03466
Sequence Information:
- Length: 938
- Mass: 105960
- Checksum: 2AF57FA2B7718330
- Sequence:
MEIKEEGASE EGQHFLPTAQ ANDPGDCQFT SIQKTPNEPQ LEFILACKDL VAPVRDRKLN TLVQISVIHP VEQSLTRYSS TEIVEGTRDP LFLTGVTFPS EYPIYEETKI KLTVYDVKDK SHDTVRTSVL PEHKDPPPEV GRSFLGYASF KVGELLKSKE QLLVLSLRTS DGGKVVGTIE VSVVKMGEIE DGEADHITTD VQGQKCALVC ECTAPESVSG KDNLPFLNSV LKNPVCKLYR FPTSDNKWMR IREQMSESIL SFHIPKELIS LHIKEDLCRN QEIKELGELS PHWDNLRKNV LTHCDQMVNM YQDILTELSK ETGSSFKSSS SKGEKTLEFV PINLHLQRMQ VHSPHLKDAL YDVITVGAPA AHFQGFKNGG LRKLLHRFET ERRNTGYQFI YYSPENTAKA KEVLSNINQL QPLIATHADL LLNSASQHSP DSLKNSLKML SEKTELFVHA FKDQLVRSAL LALYTARPGG ILKKPPSPKS STEESSPQDQ PPVMRGQDSI PHHSDYDEEE WDRVWANVGK SLNCIIAMVD KLIERDGGSE GSGGNNDGEK EPSLTDAIPS HPREDWYEQL YPLILTLKDC MGEVVNRAKQ SLTFVLLQEL AYSLPQCLML TLRRDIVFSQ ALAGLVCGFI IKLQTSLYDP GFLQQLHTVG LIVQYEGLLS TYSDEIGMLE DMAVGISDLK KVAFKIIEAK SNDVLPVITG RREHYVVEVK LPARMFESLP LQIKEGQLLH VYPVLFNVGI NEQQTLAERF GDVSLQESIN QENFELLQEY YKIFMEKMPP DYISHFQEQN DLKALLENLL QNIQSKKRKN VEIMWLAATI CRKLNGIRFT CCKSAKDRTS MSVTLEQCSI LRDEHQLHKD FFIRALDCMR SRQTQGALNE SDDPETGCLT DNKPTSRHFY PVALLLVSSH LLVVWLILSL ALLLAKYQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.