Details for: RIMS2

Gene ID: 9699

Symbol: RIMS2

Ensembl ID: ENSG00000176406

Description: regulating synaptic membrane exocytosis 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 432.7359
    Cell Significance Index: -67.3100
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 268.1324
    Cell Significance Index: -68.0100
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 54.6086
    Cell Significance Index: -67.3300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 23.9652
    Cell Significance Index: 285.6800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 9.6940
    Cell Significance Index: 610.9900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 8.9723
    Cell Significance Index: 153.7600
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 8.9337
    Cell Significance Index: 68.8600
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: 7.7874
    Cell Significance Index: 81.1200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 7.5835
    Cell Significance Index: 2720.0800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 7.4129
    Cell Significance Index: 327.8900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 7.1344
    Cell Significance Index: 270.1600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 6.1674
    Cell Significance Index: 147.9100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 5.4948
    Cell Significance Index: 337.7400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 4.4331
    Cell Significance Index: 57.4900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 4.4190
    Cell Significance Index: 3056.3500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 4.4138
    Cell Significance Index: 118.2700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 4.3490
    Cell Significance Index: 58.0200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 4.1438
    Cell Significance Index: 118.2500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 3.9760
    Cell Significance Index: 127.3500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.6855
    Cell Significance Index: 739.3100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 3.4677
    Cell Significance Index: 75.9300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 3.2567
    Cell Significance Index: 218.9800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.4654
    Cell Significance Index: 82.2300
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: 1.4393
    Cell Significance Index: 15.8800
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.4253
    Cell Significance Index: 32.9300
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 1.1057
    Cell Significance Index: 13.4000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.0353
    Cell Significance Index: 25.8800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: 0.8990
    Cell Significance Index: 11.2100
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: 0.8099
    Cell Significance Index: 9.1500
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.8077
    Cell Significance Index: 17.2700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.7906
    Cell Significance Index: 41.0700
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.7293
    Cell Significance Index: 6.0200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7257
    Cell Significance Index: 71.7900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7162
    Cell Significance Index: 646.7200
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.5479
    Cell Significance Index: 6.8400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 0.4344
    Cell Significance Index: 8.5900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4283
    Cell Significance Index: 11.9700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2276
    Cell Significance Index: 37.0200
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: 0.1600
    Cell Significance Index: 2.0200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.1276
    Cell Significance Index: 1.3900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0668
    Cell Significance Index: 12.0400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0515
    Cell Significance Index: 1.8100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0482
    Cell Significance Index: 90.7700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0435
    Cell Significance Index: 5.3500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0331
    Cell Significance Index: 3.6000
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.0242
    Cell Significance Index: 0.2300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0221
    Cell Significance Index: 34.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0091
    Cell Significance Index: -16.7100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0175
    Cell Significance Index: -0.5100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0228
    Cell Significance Index: -16.8600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0243
    Cell Significance Index: -15.2000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0358
    Cell Significance Index: -48.7100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0418
    Cell Significance Index: -6.0800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0531
    Cell Significance Index: -1.7400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0640
    Cell Significance Index: -40.6200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0715
    Cell Significance Index: -40.3400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.0795
    Cell Significance Index: -15.1200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0803
    Cell Significance Index: -1.1500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0832
    Cell Significance Index: -60.9800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0838
    Cell Significance Index: -45.7900
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0916
    Cell Significance Index: -4.8100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0987
    Cell Significance Index: -74.6800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.1072
    Cell Significance Index: -48.6600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1277
    Cell Significance Index: -26.9000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1285
    Cell Significance Index: -2.5800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1335
    Cell Significance Index: -6.0500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1338
    Cell Significance Index: -59.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1601
    Cell Significance Index: -5.1000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1644
    Cell Significance Index: -3.4900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1956
    Cell Significance Index: -56.2800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.2537
    Cell Significance Index: -50.3500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2610
    Cell Significance Index: -44.5600
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2623
    Cell Significance Index: -3.3100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.2806
    Cell Significance Index: -6.0800
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.2868
    Cell Significance Index: -3.4300
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: -0.3468
    Cell Significance Index: -3.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4178
    Cell Significance Index: -57.3800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.4478
    Cell Significance Index: -30.9700
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.4518
    Cell Significance Index: -5.1800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.4790
    Cell Significance Index: -61.4100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.5069
    Cell Significance Index: -65.4900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.5139
    Cell Significance Index: -30.8500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.5698
    Cell Significance Index: -67.2000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.5760
    Cell Significance Index: -59.9800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5764
    Cell Significance Index: -66.0400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.5978
    Cell Significance Index: -12.4000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.6079
    Cell Significance Index: -7.5400
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.6124
    Cell Significance Index: -7.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6291
    Cell Significance Index: -73.3100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6322
    Cell Significance Index: -64.5800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.6424
    Cell Significance Index: -73.3300
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.7501
    Cell Significance Index: -7.1100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.7558
    Cell Significance Index: -16.3300
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.7707
    Cell Significance Index: -47.2500
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.7820
    Cell Significance Index: -9.7200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.7975
    Cell Significance Index: -63.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.8422
    Cell Significance Index: -64.6300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.8651
    Cell Significance Index: -21.5800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.8811
    Cell Significance Index: -65.6700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.8990
    Cell Significance Index: -63.5800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** RIMS2 is a protein that plays a pivotal role in regulating synaptic membrane exocytosis. It is a member of the RIM protein family, which has been implicated in the regulation of synaptic vesicle fusion and release. The RIMS2 protein is characterized by its ability to bind to and regulate the activity of small GTPases, such as RAB3 and RAB27A, which are essential for the regulation of synaptic vesicle exocytosis. RIMS2 also interacts with other proteins, including synaptotagmin and syntaxin, to regulate the fusion of synaptic vesicles with the presynaptic membrane. **Pathways and Functions:** RIMS2 is involved in several key pathways that regulate synaptic transmission, including: 1. **Calcium-ion regulated exocytosis**: RIMS2 plays a crucial role in regulating the release of neurotransmitters in response to calcium ion influx. 2. **Adenylate cyclase-modulating G protein-coupled receptor signaling pathway**: RIMS2 interacts with G protein-coupled receptors to regulate adenylate cyclase activity, which is essential for the regulation of synaptic transmission. 3. **Intracellular protein transport**: RIMS2 is involved in the regulation of intracellular protein transport, including the transport of synaptic vesicles and neurotransmitters. 4. **Regulation of synaptic plasticity**: RIMS2 plays a crucial role in regulating synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). **Clinical Significance:** Dysregulation of RIMS2 has been implicated in various neurological disorders, including: 1. **Neurodegenerative diseases**: RIMS2 has been implicated in the regulation of synaptic transmission in neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. 2. **Neuropsychiatric disorders**: RIMS2 has been implicated in the regulation of synaptic transmission in neuropsychiatric disorders, such as schizophrenia and bipolar disorder. 3. **Neurodevelopmental disorders**: RIMS2 has been implicated in the regulation of synaptic transmission in neurodevelopmental disorders, such as autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD). In conclusion, RIMS2 is a critical regulator of synaptic membrane exocytosis, and its dysregulation has been implicated in various neurological disorders. Further research is needed to fully understand the mechanisms by which RIMS2 regulates synaptic transmission and to develop novel therapeutic strategies for the treatment of these disorders.

Genular Protein ID: 4065423595

Symbol: RIMS2_HUMAN

Name: Regulating synaptic membrane exocytosis protein 2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9872452

Title: Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 9872452

DOI: 10.1093/dnares/5.5.277

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12620390

Title: Genomic definition of RIM proteins: evolutionary amplification of a family of synaptic regulatory proteins.

PubMed ID: 12620390

DOI: 10.1016/s0888-7543(02)00024-1

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23999003

Title: SYT14L, especially its C2 domain, is involved in regulating melanocyte differentiation.

PubMed ID: 23999003

DOI: 10.1016/j.jdermsci.2013.07.010

PubMed ID: 32470375

Title: Loss of Function of RIMS2 Causes a Syndromic Congenital Cone-Rod Synaptic Disease with Neurodevelopmental and Pancreatic Involvement.

PubMed ID: 32470375

DOI: 10.1016/j.ajhg.2020.04.018

Sequence Information:

  • Length: 1411
  • Mass: 160403
  • Checksum: 9D4E83F4CBE4A864
  • Sequence:
  • MSAPVGPRGR LAPIPAASQP PLQPEMPDLS HLTEEERKII LAVMDRQKKK VKEEHKPQLT 
    QWFPFSGITE LVNNVLQPQQ KQQNEKEPQT KLHQQFEMYK EQVKKMGEES QQQQEQKGDA 
    PTCGICHKTK FADGCGHNCS YCQTKFCARC GGRVSLRSNK VMWVCNLCRK QQEILTKSGA 
    WFYNSGSNTP QQPDQKVLRG LRNEEAPQEK KPKLHEQTQF QGPSGDLSVP AVEKSRSHGL 
    TRQHSIKNGS GVKHHIASDI ASDRKRSPSV SRDQNRRYDQ REEREEYSQY ATSDTAMPRS 
    PSDYADRRSQ HEPQFYEDSD HLSYRDSNRR SHRHSKEYIV DDEDVESRDE YERQRREEEY 
    QSRYRSDPNL ARYPVKPQPY EEQMRIHAEV SRARHERRHS DVSLANADLE DSRISMLRMD 
    RPSRQRSISE RRAAMENQRS YSMERTREAQ GPSSYAQRTT NHSPPTPRRS PLPIDRPDLR 
    RTDSLRKQHH LDPSSAVRKT KREKMETMLR NDSLSSDQSE SVRPPPPKPH KSKKGGKMRQ 
    ISLSSSEEEL ASTPEYTSCD DVEIESESVS EKGDSQKGKR KTSEQAVLSD SNTRSERQKE 
    MMYFGGHSLE EDLEWSEPQI KDSGVDTCSS TTLNEEHSHS DKHPVTWQPS KDGDRLIGRI 
    LLNKRLKDGS VPRDSGAMLG LKVVGGKMTE SGRLCAFITK VKKGSLADTV GHLRPGDEVL 
    EWNGRLLQGA TFEEVYNIIL ESKPEPQVEL VVSRPIGDIP RIPDSTHAQL ESSSSSFESQ 
    KMDRPSISVT SPMSPGMLRD VPQFLSGQLS IKLWFDKVGH QLIVTILGAK DLPSREDGRP 
    RNPYVKIYFL PDRSDKNKRR TKTVKKTLEP KWNQTFIYSP VHRREFRERM LEITLWDQAR 
    VREEESEFLG EILIELETAL LDDEPHWYKL QTHDVSSLPL PHPSPYMPRR QLHGESPTRR 
    LQRSKRISDS EVSDYDCDDG IGVVSDYRHD GRDLQSSTLS VPEQVMSSNH CSPSGSPHRV 
    DVIGRTRSWS PSVPPPQSRN VEQGLRGTRT MTGHYNTISR MDRHRVMDDH YSPDRDRDCE 
    AADRQPYHRS RSTEQRPLLE RTTTRSRSTE RPDTNLMRSM PSLMTGRSAP PSPALSRSHP 
    RTGSVQTSPS STPVAGRRGR QLPQLPPKGT LDRKAGGKKL RSTVQRSTET GLAVEMRNWM 
    TRQASRESTD GSMNSYSSEG NLIFPGVRLA SDSQFSDFLD GLGPAQLVGR QTLATPAMGD 
    IQVGMMDKKG QLEVEIIRAR GLVVKPGSKT LPAPYVKVYL LDNGVCIAKK KTKVARKTLE 
    PLYQQLLSFE ESPQGKVLQI IVWGDYGRMD HKSFMGVAQI LLDELELSNM VIGWFKLFPP 
    SSLVDPTLAP LTRRASQSSL ESSTGPSYSR S

Genular Protein ID: 3456988759

Symbol: A0A8Q3SIU4_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1607
  • Mass: 181913
  • Checksum: 3C2ACC1CF8422BB5
  • Sequence:
  • MSAPVGPRGR LAPIPAASQP PLQPEMPDLS HLTEEERKII LAVMDRQKKE EEKEQSVLKV 
    KEEHKPQLTQ WFPFSGITEL VNNVLQPQQK QQNEKEPQTK LHQQFEMYKE QVKKMGEESQ 
    QQQEQKGDAP TCGICHKTKF ADGCGHNCSY CQTKFCARCG GRVSLRSNKE DKVVMWVCNL 
    CRKQQEILTK SGAWFYNSGS NTPQQPDQKV LRGLRNEEAP QEKKPKLHEQ TQFQGPSGDL 
    SVPAVEKSRS HGLTRQHSIK NGSGVKHHIA SDIASDRKRS PSVSRDQNRR YDQREEREEY 
    SQYATSDTAM PRSPSDYADR RSQHEPQFYE DSDHLSYRDS NRRSHRHSKE YIVDDEDVES 
    RDEYERQRRE EEYQSRYRSD PNLARYPVKP QPYEEQMRIH AEVSRARHER RHSDVSLANA 
    DLEDSRISML RMDRPSRQRS ISERRAAMEN QRSYSMERTR EAQGPSSYAQ RTTNHSPPTP 
    RRSPLPIDRP DLRRTDSLRK QHHLDPSSAV RKTKREKMET MLRNDSLSSD QSESVRPPPP 
    KPHKSKKGGK MRQISLSSSE EELASTPEYT SCDDVEIESE SVSEKGDSQK GKRKTSEQAV 
    LSDSNTRSER QKEMMYFGGH SLEEDLEWSE PQIKDSGVDT CSSTTLNEEH SHSDKHPVTW 
    QPSKDGDRLI GRILLNKRLK DGSVPRDSGA MLGLKVVGGK MTESGRLCAF ITKVKKGSLA 
    DTVGHLRPGD EVLEWNGRLL QGATFEEVYN IILESKPEPQ VELVVSRPIG DIPRIPDSTH 
    AQLESSSSSF ESQKMDRPSI SVTSPMSPGM LRDVPQFLSG QLSIKLWFDK VGHQLIVTIL 
    GAKDLPSRED GRPRNPYVKI YFLPDRSDKN KRRTKTVKKT LEPKWNQTFI YSPVHRREFR 
    ERMLEITLWD QARVREEESE FLGEILIELE TALLDDEPHW YKLQTHDVSS LPLPHPSPYM 
    PRRQLHGESP TRRLQRSKRI SDSEVSDYDC DDGIGVVSDY RHDGRDLQSS TLSVPEQVMS 
    SNHCSPSGSP HRVDVIGRTR SWSPSVPPPQ SRNVEQGLRG TRTMTGHYNT ISRMDRHRVM 
    DDHYSPDRDR DCEAADRQPY HRSRSTEQRP LLERTTTRSR STERPDTNLM RSMPSLMTGR 
    SAPPSPALSR SHPRTGSVQT SPSSTPVAGR RGRQLPQLPP KGTLDRKELD STRRRYAGTM 
    DIEERNRQMK INKYKQVAGS DPRLEQDYHS KYRSGWDPHR GADNVSTKSS DSDVSDISAV 
    SRTSSASRFS STSYMSVQSE RPGGNKKISV FTSKMQSRQM GISGKNMTKS TSISGDMCSL 
    EKNDGSQSDT AVGTLGTSGK KRRSSLGAKM VAIVGLSRKS RSASQLSQTE AGGKKLRSTV 
    QRSTETGLAV EMRNWMTRQA SRESTDGSMN SYSSEGNLIF PGVRLASDSQ FSDFLDGLGP 
    AQLVGRQTLA TPAMGDIQVG MMDKKGQLEV EIIRARGLVV KPGSKTLPAP YVKVYLLDNG 
    VCIAKKKTKV ARKTLEPLYQ QLLSFEESPQ GKVLQIIVWG DYGRMDHKSF MGVAQILLDE 
    LELSNMVIGW FKLFPPSSLV DPTLAPLTRR ASQSSLESST GPSYSRS

Genular Protein ID: 1514271625

Symbol: A0A994J503_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1081
  • Mass: 123201
  • Checksum: 8BE3566D54572DB9
  • Sequence:
  • MQFETLRQVC NSVLSHFHGV FSSPPNILQN ELFGQTLNNA RKRSPSVSRD QNRRYDQREE 
    REEYSQYATS DTAMPRSPSD YADRRSQHEP QFYEDSDHLS YRDSNRRSHR HSKEYIVDDE 
    DVESRDEYER QRREEEYQSR YRSDPNLARY PVKPQPYEEQ MRIHAEVSRA RHERRHSDVS 
    LANADLEDSR ISMLRMDRPS RQRSISERRA AMENQRSYSM ERTREAQGPS SYAQRTTNHS 
    PPTPRRSPLP IDRPDLRRTD SLRKQHHLDP SSAVRKTKRE KMETMLRNDS LSSDQSESVR 
    PPPPKPHKSK KGGKMRQISL SSSEEELAST PEYTSCDDVE IESESVSEKG DMDYNWLDHT 
    SWHSSEASPM SLHPVTWQPS KDGDRLIGRI LLNKRLKDGS VPRDSGAMLG LKVVGGKMTE 
    SGRLCAFITK VKKGSLADTV GHLRPGDEVL EWNGRLLQGA TFEEVYNIIL ESKPEPQVEL 
    VVSRPIGDIP RIPDSTHAQL ESSSSSFESQ KMDRPSISVT SPMSPGMLRD VPQFLSGQLS 
    IKLWFDKVGH QLIVTILGAK DLPSREDGRP RNPYVKIYFL PDRSDKNKRR TKTVKKTLEP 
    KWNQTFIYSP VHRREFRERM LEITLWDQAR VREEESEFLG EILIELETAL LDDEPHWYKL 
    QTHDVSSLPL PHPSPYMPRR QLHGESPTRR LQRSKRISDS EVSDYDCDDG IGVVSDYRHD 
    GRDLQSSTLS VPEQVMSSNH CSPSGSPHRV DVIGRTRSWS PSVPPPQSRN VEQGLRGTRT 
    MTGHYNTISR MDRHRVMDDH YSPDRDRSHP RTGSVQTSPS STPVAGRRGR QLPQLPPKGT 
    LDRKAGGKKL RSTVQRSTET GLAVEMRNWM TRQASRESTD GSMNSYSSEG NLIFPGVRLA 
    SDSQFSDFLD GLGPAQLVGR QTLATPAMGD IQVGMMDKKG QLEVEIIRAR GLVVKPGSKT 
    LPAPYVKVYL LDNGVCIAKK KTKVARKTLE PLYQQLLSFE ESPQGKVLQI IVWGDYGRMD 
    HKSFMGVAQI LLDELELSNM VIGWFKLFPP SSLVDPTLAP LTRRASQSSL ESSTGPSYSR 
    S

Genular Protein ID: 1708216291

Symbol: A0A994J5M6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1402
  • Mass: 159389
  • Checksum: 77C31AD97F3F824C
  • Sequence:
  • MSAPVGPRGR LAPIPAASQP PLQPEMPDLS HLTEEERKII LAVMDRQKKE EEKEQSVLKK 
    LHQQFEMYKE QVKKMGEESQ QQQEQKGDAP TCGICHKTKF ADGCGHNCSY CQTKFCARCG 
    GRVSLRSNKV MWVCNLCRKQ QEILTKSGAW FYNSGSNTPQ QPDQKVLRGL RNEEAPQEKK 
    PKLHEQTQFQ GPSGDLSVPA VEKSRSHGLT RQHSIKNGSG VKHHIASDIA SDRKRSPSVS 
    RDQNRRYDQR EEREEYSQYA TSDTAMPRSP SDYADRRSQH EPQFYEDSDH LSYRDSNRRS 
    HRHSKEYIVD DEDVESRDEY ERQRREEEYQ SRYRSDPNLA RYPVKPQPYE EQMRIHAEVS 
    RARHERRHSD VSLANADLED SRISMLRMDR PSRQRSISER RAAMENQRSY SMERTREAQG 
    PSSYAQRTTN HSPPTPRRSP LPIDRPDLRR TDSLRKQHHL DPSSAVRKTK REKMETMLRN 
    DSLSSDQSES VRPPPPKPHK SKKGGKMRQI SLSSSEEELA STPEYTSCDD VEIESESVSE 
    KGDSQKGKRK TSEQAVLSDS NTRSERQKEM MYFGGHSLEE DLEWSEPQIK DSGVDTCSST 
    TLNEEHSHSD KHPVTWQPSK DGDRLIGRIL LNKRLKDGSV PRDSGAMLGL KVVGGKMTES 
    GRLCAFITKV KKGSLADTVG HLRPGDEVLE WNGRLLQGAT FEEVYNIILE SKPEPQVELV 
    VSRPIGDIPR IPDSTHAQLE SSSSSFESQK MDRPSISVTS PMSPGMLRDV PQFLSGQLSI 
    KLWFDKVGHQ LIVTILGAKD LPSREDGRPR NPYVKIYFLP DRSDKNKRRT KTVKKTLEPK 
    WNQTFIYSPV HRREFRERML EITLWDQARV REEESEFLGE ILIELETALL DDEPHWYKLQ 
    THDVSSLPLP HPSPYMPRRQ LHGESPTRRL QRSKRISDSE VSDYDCDDGI GVVSDYRHDG 
    RDLQSSTLSV PEQVMSSNHC SPSGSPHRVD VIGRTRSWSP SVPPPQSRNV EQGLRGTRTM 
    TGHYNTISRM DRHRVMDDHY SPDRDSHFLT LPRSRYSQTI DHHHRDGRDC EAADRQPYHR 
    SRSTEQRPLL ERTTTRSRST ERPDTNLMRS MPSLMTGRSA PPSPALSRSH PRTGSVQTSP 
    SSTPVAGRRG RQLPQLPPKG TLDRKAGGKK LRSTVQRSTE TGLAVEMRNW MTRQASREST 
    DGSMNSYSSE GNLIFPGVRL ASDSQFSDFL DGLGPAQLVG RQTLATPAMG DIQVGMMDKK 
    GQLEVEIIRA RGLVVKPGSK TLPAPYVKVY LLDNGVCIAK KKTKVARKTL EPLYQQLLSF 
    EESPQGKVLQ IIVWGDYGRM DHKSFMGVAQ ILLDELELSN MVIGWFKLFP PSSLVDPTLA 
    PLTRRASQSS LESSTGPSYS RS

Genular Protein ID: 3812064721

Symbol: A0A994J7W6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1103
  • Mass: 125844
  • Checksum: A4C8393C814C6930
  • Sequence:
  • MQFETLRQVC NSVLSHFHGV FSSPPNILQN ELFGQTLNNA RKRSPSVSRD QNRRYDQREE 
    REEYSQYATS DTAMPRSPSD YADRRSQHEP QFYEDSDHLS YRDSNRRSHR HSKEYIVDDE 
    DVESRDEYER QRREEEYQSR YRSDPNLARY PVKPQPYEEQ MRIHAEVSRA RHERRHSDVS 
    LANADLEDSR ISMLRMDRPS RQRSISERRA AMENQRSYSM ERTREAQGPS SYAQRTTNHS 
    PPTPRRSPLP IDRPDLRRTD SLRKQHHLDP SSAVRKTKRE KMETMLRNDS LSSDQSESVR 
    PPPPKPHKSK KGGKMRQISL SSSEEELAST PEYTSCDDVE IESESVSEKG DMDYNWLDHT 
    SWHSSEASPM SLHPVTWQPS KDGDRLIGRI LLNKRLKDGS VPRDSGAMLG LKVVGGKMTE 
    SGRLCAFITK VKKGSLADTV GHLRPGDEVL EWNGRLLQGA TFEEVYNIIL ESKPEPQVEL 
    VVSRPIGDIP RIPDSTHAQL ESSSSSFESQ KMDRPSISVT SPMSPGMLRD VPQFLSGQLS 
    IKLWFDKVGH QLIVTILGAK DLPSREDGRP RNPYVKIYFL PDRSDKNKRR TKTVKKTLEP 
    KWNQTFIYSP VHRREFRERM LEITLWDQAR VREEESEFLG EILIELETAL LDDEPHWYKL 
    QTHDVSSLPL PHPSPYMPRR QLHGESPTRR LQRSKRISDS EVSDYDCDDG IGVVSDYRHD 
    GRDLQSSTLS VPEQVMSSNH CSPSGSPHRV DVIGRTRSWS PSVPPPQSRN VEQGLRGTRT 
    MTGHYNTISR MDRHRVMDDH YSPDRDSHFL TLPRSRYSQT IDHHHRDGRS HPRTGSVQTS 
    PSSTPVAGRR GRQLPQLPPK GTLDRKAGGK KLRSTVQRST ETGLAVEMRN WMTRQASRES 
    TDGSMNSYSS EGNLIFPGVR LASDSQFSDF LDGLGPAQLV GRQTLATPAM GDIQVGMMDK 
    KGQLEVEIIR ARGLVVKPGS KTLPAPYVKV YLLDNGVCIA KKKTKVARKT LEPLYQQLLS 
    FEESPQGKVL QIIVWGDYGR MDHKSFMGVA QILLDELELS NMVIGWFKLF PPSSLVDPTL 
    APLTRRASQS SLESSTGPSY SRS

Genular Protein ID: 3719072220

Symbol: F8W6W8_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

Sequence Information:

  • Length: 1356
  • Mass: 153781
  • Checksum: 1560DF19A3372895
  • Sequence:
  • MQFETLRQVC NSVLSHFHGV FSSPPNILQN ELFGQTLNNA RKRSPSVSRD QNRRYDQREE 
    REEYSQYATS DTAMPRSPSD YADRRSQHEP QFYEDSDHLS YRDSNRRSHR HSKEYIVDDE 
    DVESRDEYER QRREEEYQSR YRSDPNLARY PVKPQPYEEQ MRIHAEVSRA RHERRHSDVS 
    LANADLEDSR ISMLRMDRPS RQRSISERRA AMENQRSYSM ERTREAQGPS SYAQRTTNHS 
    PPTPRRSPLP IDRPDLRRTD SLRKQHHLDP SSAVRKTKRE KMETMLRNDS LSSDQSESVR 
    PPPPKPHKSK KGGKMRQISL SSSEEELAST PEYTSCDDVE IESESVSEKG DMDYNWLDHT 
    SWHSSEASPM SLHPVTWQPS KDGDRLIGRI LLNKRLKDGS VPRDSGAMLG LKVVGGKMTE 
    SGRLCAFITK VKKGSLADTV GHLRPGDEVL EWNGRLLQGA TFEEVYNIIL ESKPEPQVEL 
    VVSRPIGDIP RIPDSTHAQL ESSSSSFESQ KMDRPSISVT SPMSPGMLRD VPQFLSGQLS 
    IKLWFDKVGH QLIVTILGAK DLPSREDGRP RNPYVKIYFL PDRSDKNKRR TKTVKKTLEP 
    KWNQTFIYSP VHRREFRERM LEITLWDQAR VREEESEFLG EILIELETAL LDDEPHWYKL 
    QTHDVSSLPL PHPSPYMPRR QLHGESPTRR LQRSKRISDS EVSDYDCDDG IGVVSDYRHD 
    GRDLQSSTLS VPEQVMSSNH CSPSGSPHRV DVIGRTRSWS PSVPPPQSRN VEQGLRGTRT 
    MTGHYNTISR MDRHRVMDDH YSPDRDSHFL TLPRSRYSQT IDHHHRDGRD CEAADRQPYH 
    RSRSTEQRPL LERTTTRSRS TERPDTNLMR SMPSLMTGRS APPSPALSRS HPRTGSVQTS 
    PSSTPVAGRR GRQLPQLPPK GTLDRNNGVK EIEPYEELDS TRRRYAGTMD IEERNRQMKI 
    NKYKQVAGSD PRLEQDYHSK YRSGWDPHRG ADNVSTKSSD SDVSDISAVS RTSSASRFSS 
    TSYMSVQSER PGGNKKISVF TSKMQSRQMG ISGKNMTKST SISGDMCSLE KNDGSQSDTA 
    VGTLGTSGKK RRSSLGAKMV AIVGLSRKSR SASQLSQTEA GGKKLRSTVQ RSTETGLAVE 
    MRNWMTRQAS RESTDGSMNS YSSEGNLIFP GVRLASDSQF SDFLDGLGPA QLVGRQTLAT 
    PAMGDIQVGM MDKKGQLEVE IIRARGLVVK PGSKTLPAPY VKVYLLDNGV CIAKKKTKVA 
    RKTLEPLYQQ LLSFEESPQG KVLQIIVWGD YGRMDHKSFM GVAQILLDEL ELSNMVIGWF 
    KLFPPSSLVD PTLAPLTRRA SQSSLESSTG PSYSRS

Genular Protein ID: 2449500785

Symbol: A0A8Q3SJ53_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16421571

Title: DNA sequence and analysis of human chromosome 8.

PubMed ID: 16421571

DOI: 10.1038/nature04406

Sequence Information:

  • Length: 1324
  • Mass: 149890
  • Checksum: D59850D39BD3DA71
  • Sequence:
  • MQFETLRQVC NSVLSHFHGV FSSPPNILQN ELFGQTLNNA RKRSPSVSRD QNRRYDQREE 
    REEYSQYATS DTAMPRSPSD YADRRSQHEP QFYEDSDHLS YRDSNRRSHR HSKEYIVDDE 
    DVESRDEYER QRREEEYQSR YRSDPNLARY PVKPQPYEEQ MRIHAEVSRA RHERRHSDVS 
    LANADLEDSR ISMLRMDRPS RQRSISERRA AMENQRSYSM ERTREAQGPS SYAQRTTNHS 
    PPTPRRSPLP IDRPDLRRTD SLRKQHHLDP SSAVRKTKRE KMETMLRNDS LSSDQSESVR 
    PPPPKPHKSK KGGKMRQISL SSSEEELAST PEYTSCDDVE IESESVSEKG DMDYNWLDHT 
    SWHSSEASPM SLHPVTWQPS KDGDRLIGRI LLNKRLKDGS VPRDSGAMLG LKVVGGKMTE 
    SGRLCAFITK VKKGSLADTV GHLRPGDEVL EWNGRLLQGA TFEEVYNIIL ESKPEPQVEL 
    VVSRPIGDIP RIPDSTHAQL ESSSSSFESQ KMDRPSISVT SPMSPGMLRD VPQFLSGQLS 
    IKLWFDKVGH QLIVTILGAK DLPSREDGRP RNPYVKIYFL PDRSDKNKRR TKTVKKTLEP 
    KWNQTFIYSP VHRREFRERM LEITLWDQAR VREEESEFLG EILIELETAL LDDEPHWYKL 
    QTHDVSSLPL PHPSPYMPRR QLHGESPTRR LQRSKRISDS EVSDYDCDDG IGVVSDYRHD 
    GRDLQSSTLS VPEQVMSSNH CSPSGSPHRV DVIGRTRSWS PSVPPPQSRN VEQGLRGTRT 
    MTGHYNTISR MDRHRVMDDH YSPDRDRDCE AADRQPYHRS RSTEQRPLLE RTTTRSRSTE 
    RPDTNLMRSM PSLMTGRSAP PSPALSRSHP RTGSVQTSPS STPVAGRRGR QLPQLPPKGT 
    LDRNNGVKEI EPYEGTMDIE ERNRQMKINK YKQVAGSDPR LEQDYHSKYR SGWDPHRGAD 
    NVSTKSSDSD VSDISAVSRT SSASRFSSTS YMSVQSERPG GNKKISVFTS KMQSRQMGIS 
    GKNMTKSTSI SGDMCSLEKN DGSQSDTAVG TLGTSGKKRR SSLGAKMVAI VGLSRKSRSA 
    SQLSQTEAGG KKLRSTVQRS TETGLAVEMR NWMTRQASRE STDGSMNSYS SEGNLIFPGV 
    RLASDSQFSD FLDGLGPAQL VGRQTLATPA MGDIQVGMMD KKGQLEVEII RARGLVVKPG 
    SKTLPAPYVK VYLLDNGVCI AKKKTKVARK TLEPLYQQLL SFEESPQGKV LQIIVWGDYG 
    RMDHKSFMGV AQILLDELEL SNMVIGWFKL FPPSSLVDPT LAPLTRRASQ SSLESSTGPS 
    YSRS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.